Experiment set2IT071 for Escherichia coli BW25113

Compare to:

LB with 2-Furfuraldehyde 0.125 vol%

200 most important genes:

  gene name fitness t score description  
b3792 wzxE -3.2 -6.1 O-antigen translocase (NCBI) compare
b0145 dksA -3.2 -3.1 DNA-binding transcriptional regulator of rRNA transcription, DnaK suppressor protein (NCBI) compare
b0142 folK -3.1 -1.9 2-amino-4-hydroxy-6-hydroxymethyldihyropteridine pyrophosphokinase (NCBI) compare
b1085 b1085 -3.0 -2.5 orf, hypothetical protein (VIMSS) compare
b2808 gcvA -2.9 -4.7 DNA-binding transcriptional dual regulator (NCBI) compare
b2938 speA -2.7 -10.3 arginine decarboxylase (NCBI) compare
b0630 lipB -2.5 -2.3 protein of lipoate biosynthesis (VIMSS) compare
b2784 relA -2.5 -8.6 (p)ppGpp synthetase I/GTP pyrophosphokinase (NCBI) compare
b0082 mraW -2.5 -4.0 S-adenosyl-methyltransferase (NCBI) compare
b2937 speB -2.4 -7.0 agmatinase (NCBI) compare
b2567 rnc -2.4 -2.2 ribonuclease III (NCBI) compare
b1861 ruvA -2.4 -3.0 Holliday junction DNA helicase motor protein (NCBI) compare
b1984 asnW -2.4 -2.0 tRNA-Asn (NCBI) compare
b3341 rpsG -2.3 -1.5 30S ribosomal protein S7 (NCBI) compare
b2911 ssrS -2.3 -1.5 6S regulatory RNA (NCBI) compare
b0386 proC -2.3 -6.4 pyrroline-5-carboxylate reductase (NCBI) compare
b3778 rep -2.3 -7.9 DNA helicase and single-stranded DNA-dependent ATPase (NCBI) compare
b2330 yfcB -2.2 -2.9 putative adenine-specific methylase (VIMSS) compare
b2830 nudH -2.2 -2.0 dinucleoside polyphosphate hydrolase (NCBI) compare
b3741 gidA -2.0 -6.3 glucose-inhibited division protein A (NCBI) compare
b3183 obgE -2.0 -1.9 GTPase involved in cell partioning and DNA repair (NCBI) compare
b2820 recB -2.0 -1.4 exonuclease V (RecBCD complex), beta subunit (NCBI) compare
b1286 rnb -2.0 -3.8 exoribonuclease II (NCBI) compare
b0059 hepA -2.0 -12.6 ATP-dependent helicase HepA (NCBI) compare
b2829 ptsP -2.0 -10.9 fused PTS enzyme: PEP-protein phosphotransferase (enzyme I)/GAF domain containing protein (NCBI) compare
b3871 bipA -1.9 -9.1 GTP-binding protein (NCBI) compare
b3706 trmE -1.8 -5.0 tRNA modification GTPase (NCBI) compare
b3609 secB -1.8 -4.2 export protein SecB (NCBI) compare
b4171 miaA -1.8 -5.1 tRNA delta(2)-isopentenylpyrophosphate transferase (NCBI) compare
b1576 ydfD -1.8 -3.1 Qin prophage; predicted protein (NCBI) compare
b3781 trxA -1.8 -3.7 thioredoxin 1 (VIMSS) compare
b0739 tolA -1.8 -4.3 cell envelope integrity inner membrane protein TolA (NCBI) compare
b2894 xerD -1.7 -1.6 site-specific tyrosine recombinase XerD (NCBI) compare
b2912 ygfA -1.7 -2.7 putative ligase (VIMSS) compare
b4239 treC -1.7 -4.3 trehalose-6-P hydrolase (NCBI) compare
b3472 b3472 -1.7 -6.7 orf, hypothetical protein (VIMSS) compare
b1865 nudB -1.7 -1.4 dATP pyrophosphohydrolase (NCBI) compare
b2904 gcvH -1.6 -2.1 glycine cleavage system protein H (NCBI) compare
b3387 dam -1.6 -9.2 DNA adenine methylase (NCBI) compare
b0849 grxA -1.6 -2.3 glutaredoxin 1, redox coenzyme for ribonucleotide reductase (RNR1a) (NCBI) compare
b1613 manA -1.6 -2.6 mannose-6-phosphate isomerase (VIMSS) compare
b3811 xerC -1.6 -1.1 site-specific tyrosine recombinase XerC (NCBI) compare
b1804 rnd -1.6 -3.2 ribonuclease D (NCBI) compare
b0890 ftsK -1.5 -6.2 DNA-binding membrane protein required for chromosome resolution and partitioning (NCBI) compare
b2236 yfaE -1.5 -2.8 predicted 2Fe-2S cluster-containing protein (NCBI) compare
b3181 greA -1.5 -3.8 transcription elongation factor: cleaves 3' nucleotide of paused mRNA (VIMSS) compare
b2903 gcvP -1.5 -8.2 glycine dehydrogenase (NCBI) compare
b0767 ybhE -1.5 -3.7 6-phosphogluconolactonase (NCBI) compare
b2699 recA -1.5 -1.9 recombinase A (NCBI) compare
b1192 ldcA -1.5 -4.2 L,D-carboxypeptidase A (NCBI) compare
b4177 purA -1.5 -2.0 adenylosuccinate synthetase (NCBI) compare
b2175 spr -1.5 -3.4 predicted peptidase, outer membrane lipoprotein (NCBI) compare
b0149 mrcB -1.5 -9.0 penicillin-binding protein 1b (NCBI) compare
b3206 npr -1.5 -4.2 phosphohistidinoprotein-hexose phosphotransferase component of N-regulated PTS system (Npr) (NCBI) compare
b2935 tktA -1.5 -2.1 transketolase 1, thiamin-binding (NCBI) compare
b0741 pal -1.5 -4.1 peptidoglycan-associated outer membrane lipoprotein (NCBI) compare
b2905 gcvT -1.5 -4.9 glycine cleavage system aminomethyltransferase T (NCBI) compare
b1150 ymfR -1.5 -1.4 e14 prophage; predicted protein (NCBI) compare
b3033 yqiB -1.4 -3.5 predicted dehydrogenase (NCBI) compare
b1831 proQ -1.4 -3.8 putative solute/DNA competence effector (NCBI) compare
b0726 sucA -1.4 -3.0 alpha-ketoglutarate decarboxylase (NCBI) compare
b1551 b1551 -1.4 -2.4 orf, hypothetical protein (VIMSS) compare
b3806 cyaA -1.4 -4.6 adenylate cyclase (NCBI) compare
b1685 ydiH -1.4 -1.6 predicted protein (RefSeq) compare
b1942 fliJ -1.4 -1.5 flagellar biosynthesis chaperone (NCBI) compare
b2287 nuoB -1.3 -3.3 NADH dehydrogenase subunit B (NCBI) compare
b3493 pitA -1.3 -6.2 phosphate transporter, low-affinity (NCBI) compare
b1279 yciS -1.3 -1.6 conserved inner membrane protein (NCBI) compare
b1863 ruvC -1.3 -3.1 Holliday junction resolvase (NCBI) compare
b0957 ompA -1.3 -3.5 outer membrane protein A (3a;II*;G;d) (NCBI) compare
b2576 srmB -1.3 -3.0 ATP-dependent RNA helicase (NCBI) compare
b4655 ythA -1.3 -1.1 expressed protein (RefSeq) compare
b4515 ybgT -1.2 -1.6 hypothetical protein (NCBI) compare
b2285 nuoE -1.2 -2.0 NADH dehydrogenase subunit E (NCBI) compare
b0738 tolR -1.2 -2.9 membrane spanning protein in TolA-TolQ-TolR complex (NCBI) compare
b0580 ybdJ -1.2 -1.5 predicted inner membrane protein (NCBI) compare
b0737 tolQ -1.2 -2.5 membrane spanning protein in TolA-TolQ-TolR complex (NCBI) compare
b2642 yfjW -1.2 -2.5 CP4-57 prophage; predicted inner membrane protein (NCBI) compare
b4000 hupA -1.2 -3.4 HU, DNA-binding transcriptional regulator, alpha subunit (NCBI) compare
b3261 fis -1.2 -2.6 DNA-binding protein Fis (NCBI) compare
b3791 rffA -1.1 -5.1 TDP-4-oxo-6-deoxy-D-glucose transaminase (NCBI) compare
b3613 yibP -1.1 -4.0 putative membrane protein (VIMSS) compare
b2055 wcaE -1.1 -1.8 predicted glycosyl transferase (NCBI) compare
b4451 ryhB -1.1 -1.1 Regulatory sRNA mediating positive Fur regulon response; requires Hfq for function; global iron regulator; degraded by RNase E when bound to target (RefSeq) compare
b2822 recC -1.1 -3.4 exonuclease V (RecBCD complex), gamma chain (NCBI) compare
b1358 ydaT -1.1 -1.3 Rac prophage; predicted protein (NCBI) compare
b1058 yceO -1.1 -1.2 hypothetical protein (NCBI) compare
b2659 b2659 -1.0 -1.6 orf, hypothetical protein (VIMSS) compare
b0118 acnB -1.0 -2.4 aconitate hydratase (NCBI) compare
b2297 pta -1.0 -1.4 phosphate acetyltransferase (NCBI) compare
b2288 nuoA -1.0 -2.4 NADH dehydrogenase I chain A (VIMSS) compare
b4529 ydbJ -1.0 -1.1 hypothetical protein (NCBI) compare
b3784 rfe -1.0 -6.8 UDP-GlcNAc:undecaprenylphosphate GlcNAc-1-phosphate transferase (NCBI) compare
b3121 yhaC -1.0 -1.8 hypothetical protein (NCBI) compare
b0127 yadG -1.0 -3.4 predicted transporter subunit: ATP-binding component of ABC superfamily (NCBI) compare
b4201 priB -1.0 -1.4 primosomal replication protein N (NCBI) compare
b0028 fkpB -1.0 -3.5 FKBP-type peptidyl-prolyl cis-trans isomerase (rotamase) (NCBI) compare
b4503 yafF -1.0 -1.1 no description compare
b4505 insX -0.9 -1.2 predicted IS protein (RefSeq) compare
b1147 ymfL -0.9 -2.2 e14 prophage; predicted DNA-binding transcriptional regulator (RefSeq) compare
b4613 dinQ -0.9 -1.2 Damage inducible, function unknown (RefSeq) compare
b4558 yifL -0.9 -2.8 predicted lipoprotein (NCBI) compare
b4647 mokA -0.9 -1.2 no description compare
b1530 marR -0.9 -2.8 multiple antibiotic resistance protein; repressor of mar operon (VIMSS) compare
b1730 ydjO -0.9 -2.3 predicted protein (RefSeq) compare
b1259 yciG -0.9 -1.9 orf, hypothetical protein (VIMSS) compare
b0053 surA -0.9 -3.0 peptidyl-prolyl cis-trans isomerase (PPIase) (NCBI) compare
b4375 prfC -0.9 -4.0 peptide chain release factor 3 (NCBI) compare
b3290 trkA -0.9 -2.4 potassium transporter peripheral membrane component (NCBI) compare
b3199 yrbK -0.9 -1.8 hypothetical protein (NCBI) compare
b2282 nuoH -0.9 -2.1 NADH dehydrogenase subunit H (NCBI) compare
b1853 yebK -0.9 -1.8 predicted DNA-binding transcriptional regulator (NCBI) compare
b4172 hfq -0.9 -1.4 RNA-binding protein Hfq (NCBI) compare
b1850 eda -0.9 -1.6 keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase (NCBI) compare
b0705 ybfL -0.9 -2.0 putative receptor protein (VIMSS) compare
b3935 priA -0.9 -1.9 primosome assembly protein PriA (NCBI) compare
b2625 yfjI -0.9 -3.7 CP4-57 prophage; predicted protein (NCBI) compare
b3790 rffC -0.9 -3.1 TDP-fucosamine acetyltransferase (RefSeq) compare
b2569 lepA -0.9 -2.6 GTP-binding protein LepA (NCBI) compare
b3725 pstB -0.9 -1.7 phosphate transporter subunit (NCBI) compare
b1086 rluC -0.9 -3.4 23S rRNA pseudouridylate synthase (NCBI) compare
b3131 agaR -0.9 -2.5 DNA-binding transcriptional dual regulator (NCBI) compare
b1179 ycgL -0.8 -1.7 conserved protein (NCBI) compare
b3160 yhbW -0.8 -4.4 predicted enzyme (NCBI) compare
b3120 yhaB -0.8 -2.2 orf, hypothetical protein (VIMSS) compare
b0125 hpt -0.8 -2.8 hypoxanthine phosphoribosyltransferase (VIMSS) compare
b2318 truA -0.8 -2.4 tRNA pseudouridine synthase A (NCBI) compare
b3961 oxyR -0.8 -5.0 DNA-binding transcriptional dual regulator (NCBI) compare
b0889 lrp -0.8 -1.7 DNA-binding transcriptional dual regulator, leucine-binding (NCBI) compare
b3035 tolC -0.8 -4.2 outer membrane channel; specific tolerance to colicin E1; segregation of daughter chromosomes (VIMSS) compare
b2393 nupC -0.8 -3.3 nucleoside (except guanosine) transporter (NCBI) compare
b1361 ydaW -0.8 -1.0 orf, hypothetical protein (VIMSS) compare
b4685 yrbN -0.8 -1.5 expressed protein (RefSeq) compare
b4426 isrA -0.8 -1.8 unknown RNA (NCBI) compare
b0436 tig -0.8 -4.2 trigger factor (NCBI) compare
b2014 yeeF -0.8 -4.4 putative amino acid/amine transport protein (VIMSS) compare
b1726 yniB -0.8 -1.6 predicted inner membrane protein (NCBI) compare
b1591 b1591 -0.8 -1.3 putative oxidoreductase component (VIMSS) compare
b3405 ompR -0.8 -2.7 osmolarity response regulator (NCBI) compare
b4227 ytfQ -0.8 -2.5 predicted sugar transporter subunit: periplasmic-binding component of ABC superfamily (NCBI) compare
b3163 nlpI -0.8 -2.6 hypothetical protein (NCBI) compare
b2617 smpA -0.8 -1.9 small membrane protein A (VIMSS) compare
b3463 ftsE -0.8 -2.5 predicted transporter subunit: ATP-binding component of ABC superfamily (NCBI) compare
b3414 gntY -0.8 -3.2 predicted gluconate transport associated protein (NCBI) compare
b2276 nuoN -0.8 -2.8 NADH:ubiquinone oxidoreductase, membrane subunit N (RefSeq) compare
b3026 qseC -0.8 -2.6 sensory histidine kinase in two-component regulatory system with QseB (NCBI) compare
b4481 rffT -0.8 -3.3 4-alpha-L-fucosyltransferase (NCBI) compare
b1480 sra -0.8 -1.6 30S ribosomal subunit protein S22 (NCBI) compare
b0471 ybaB -0.8 -2.0 hypothetical protein (NCBI) compare
b3184 yhbE -0.8 -4.0 conserved inner membrane protein (NCBI) compare
b1273 yciN -0.7 -1.3 hypothetical protein (NCBI) compare
b4146 yjeK -0.7 -1.8 predicted lysine aminomutase (NCBI) compare
b1363 trkG -0.7 -2.9 Rac prophage; potassium transporter subunit (NCBI) compare
b1926 fliT -0.7 -1.9 predicted chaperone (NCBI) compare
b1304 pspA -0.7 -2.4 regulatory protein for phage-shock-protein operon (NCBI) compare
b3029 ygiN -0.7 -1.6 quinol monooxygenase (NCBI) compare
b4443 gcvB -0.7 -0.7 GcvB sRNA gene divergent from gcvA (RefSeq) compare
b2038 rfbC -0.7 -3.9 dTDP-4-deoxyrhamnose-3,5-epimerase (NCBI) compare
b2277 nuoM -0.7 -3.1 NADH dehydrogenase subunit M (NCBI) compare
b2352 yfdI -0.7 -2.4 CPS-53 (KpLE1) prophage; predicted inner membrane protein (NCBI) compare
b0219 yafV -0.7 -1.7 predicted C-N hydrolase family amidase, NAD(P)-binding (NCBI) compare
b1257 yciE -0.7 -1.6 hypothetical protein (NCBI) compare
b1129 phoQ -0.7 -3.6 sensory histidine kinase in two-compoent regulatory system with PhoP (NCBI) compare
b0406 tgt -0.7 -3.3 queuine tRNA-ribosyltransferase (NCBI) compare
b3652 recG -0.7 -4.1 ATP-dependent DNA helicase (NCBI) compare
b3443 yrhA -0.7 -1.8 orf, hypothetical protein (VIMSS) compare
b1724 ydiZ -0.7 -1.2 hypothetical protein (NCBI) compare
b0407 yajC -0.7 -1.7 preprotein translocase subunit YajC (NCBI) compare
b3740 gidB -0.7 -4.3 glucose-inhibited division protein B (NCBI) compare
b2532 yfhQ -0.7 -2.0 predicted methyltransferase (NCBI) compare
b1238 tdk -0.7 -3.5 thymidine kinase (NCBI) compare
b2279 nuoK -0.7 -1.2 NADH dehydrogenase subunit K (NCBI) compare
b1642 slyA -0.7 -1.1 transcriptional regulator for cryptic hemolysin (VIMSS) compare
b0487 cueR -0.7 -1.9 DNA-binding transcriptional activator of copper-responsive regulon genes (NCBI) compare
b0603 ybdO -0.7 -1.6 predicted DNA-binding transcriptional regulator (NCBI) compare
b2513 yfgM -0.7 -2.8 hypothetical protein (NCBI) compare
b4240 treB -0.7 -4.2 fused trehalose(maltose)-specific PTS enzyme: IIB component/IIC component (NCBI) compare
b1954 dsrA -0.7 -1.1 regulatory antisense RNA (NCBI) compare
b1849 purT -0.7 -2.3 phosphoribosylglycinamide formyltransferase 2 (NCBI) compare
b2278 nuoL -0.7 -3.8 NADH dehydrogenase subunit L (NCBI) compare
b3870 glnA -0.6 -1.4 glutamine synthetase (NCBI) compare
b1484 ddpD -0.6 -2.8 D-ala-D-ala transporter subunit (NCBI) compare
b2195 ccmG -0.6 -1.3 periplasmic thioredoxin of cytochrome c-type biogenesis (NCBI) compare
b1088 yceD -0.6 -1.9 hypothetical protein (NCBI) compare
b2531 iscR -0.6 -1.0 DNA-binding transcriptional repressor (NCBI) compare
b1307 pspD -0.6 -1.1 peripheral inner membrane phage-shock protein (NCBI) compare
b2209 eco -0.6 -1.4 ecotin precursor (NCBI) compare
b3462 ftsX -0.6 -2.5 predicted transporter subunit: membrane component of ABC superfamily (NCBI) compare
b0326 yahL -0.6 -3.6 hypothetical protein (NCBI) compare
b1383 ydbL -0.6 -1.6 orf, hypothetical protein (VIMSS) compare
b2343 b2343 -0.6 -0.9 orf, hypothetical protein (VIMSS) compare
b1603 pntA -0.6 -1.6 NAD(P) transhydrogenase subunit alpha (NCBI) compare
b3146 yraL -0.6 -2.9 predicted methyltransferase (NCBI) compare
b2021 hisC -0.6 -2.1 histidinol-phosphate aminotransferase (NCBI) compare
b1497 b1497 -0.6 -1.9 putative enzyme (VIMSS) compare
b1731 cedA -0.6 -1.4 cell division modulator (RefSeq) compare
b2847 yqeI -0.6 -3.1 predicted transcriptional regulator (NCBI) compare
b1919 yedO -0.6 -1.7 putative 1-aminocyclopropane-1-carboxylate deaminase (VIMSS) compare
b3916 pfkA -0.6 -1.6 6-phosphofructokinase (NCBI) compare
b2951 yggS -0.6 -1.6 predicted enzyme (NCBI) compare


Specific Phenotypes

For 1 genes in this experiment

For stress 2-Furfuraldehyde in Escherichia coli BW25113

For stress 2-Furfuraldehyde across organisms