Experiment set2IT037 for Pseudomonas sp. RS175

Compare to:

Citric Acid carbon source 10 mM

200 most important genes:

  gene name fitness t score description  
PFR28_00683 -6.7 -4.6 Transcriptional regulatory protein tctD compare
PFR28_05016 -6.3 -14.6 Glutamate synthase [NADPH] small chain compare
PFR28_05015 -5.4 -30.2 Glutamate synthase [NADPH] large chain compare
PFR28_00681 -5.3 -16.3 hypothetical protein compare
PFR28_02821 -5.3 -22.3 3-isopropylmalate dehydrogenase compare
PFR28_02603 -5.0 -9.6 Siroheme synthase compare
PFR28_02811 -4.9 -5.8 Amidophosphoribosyltransferase compare
PFR28_05105 -4.8 -13.7 Phosphoserine phosphatase SerB2 compare
PFR28_03363 -4.8 -21.7 Ornithine carbamoyltransferase 1, anabolic compare
PFR28_04308 -4.7 -3.2 Amino-acid acetyltransferase compare
PFR28_04832 -4.6 -15.9 putative phosphatase compare
PFR28_02823 -4.6 -4.5 3-isopropylmalate dehydratase small subunit 1 compare
PFR28_01365 -4.6 -8.8 hypothetical protein compare
PFR28_00684 -4.6 -21.0 Sensor protein QseC compare
PFR28_02824 -4.5 -8.2 3-isopropylmalate dehydratase large subunit compare
PFR28_04834 -4.5 -21.0 L-threonine dehydratase biosynthetic IlvA compare
PFR28_04930 -4.5 -12.9 Imidazole glycerol phosphate synthase subunit HisH compare
PFR28_03697 -4.3 -16.4 Ketol-acid reductoisomerase (NADP(+)) compare
PFR28_04202 -4.2 -8.0 5,10-methylenetetrahydrofolate reductase compare
PFR28_04278 -4.2 -16.7 Dihydroxy-acid dehydratase compare
PFR28_00188 -4.0 -14.9 Histidinol-phosphate aminotransferase compare
PFR28_03860 -3.8 -5.8 putative murein peptide carboxypeptidase compare
PFR28_04933 -3.8 -4.9 Imidazole glycerol phosphate synthase subunit HisF compare
PFR28_00187 -3.8 -14.3 Histidinol dehydrogenase compare
PFR28_04246 -3.8 -15.1 Bifunctional methionine biosynthesis protein MetXA/MetW compare
PFR28_03699 -3.7 -11.9 Acetolactate synthase isozyme 3 large subunit compare
PFR28_03698 -3.7 -13.2 Acetolactate synthase isozyme 3 small subunit compare
PFR28_03718 -3.6 -6.9 Transcriptional regulatory protein ZraR compare
PFR28_00186 -3.6 -6.6 ATP phosphoribosyltransferase compare
PFR28_01366 -3.6 -11.2 Sulfite reductase [ferredoxin] compare
PFR28_04985 -3.4 -7.3 Phosphoribosyl-ATP pyrophosphatase compare
PFR28_05125 -3.4 -10.4 ATP phosphoribosyltransferase regulatory subunit compare
PFR28_03217 -3.4 -4.0 Phosphoribosylformylglycinamidine cyclo-ligase compare
PFR28_04929 -3.4 -8.5 Histidine biosynthesis bifunctional protein HisB compare
PFR28_04245 -3.4 -16.4 Homoserine O-succinyltransferase compare
PFR28_02810 -3.3 -17.5 O-succinylhomoserine sulfhydrylase compare
PFR28_03218 -3.2 -8.5 Phosphoribosylglycinamide formyltransferase compare
PFR28_04842 -3.2 -7.5 D-3-phosphoglycerate dehydrogenase compare
PFR28_04932 -3.1 -6.5 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase compare
PFR28_00193 -3.1 -13.2 Sulfate adenylyltransferase subunit 2 compare
PFR28_00305 -3.0 -10.6 2-isopropylmalate synthase compare
PFR28_00194 -3.0 -12.3 Bifunctional enzyme CysN/CysC compare
PFR28_00966 -3.0 -18.5 HTH-type transcriptional regulator CysB compare
PFR28_04986 -2.9 -6.1 Phosphoribosyl-AMP cyclohydrolase compare
PFR28_01040 -2.9 -12.9 Putative 4-hydroxy-4-methyl-2-oxoglutarate aldolase compare
PFR28_03012 -2.8 -8.3 Phosphate acyltransferase compare
PFR28_04945 -2.7 -6.9 Sensory histidine kinase/phosphatase NtrB compare
PFR28_03282 -2.7 -12.1 Arginine N-succinyltransferase subunit alpha compare
PFR28_04874 -2.6 -12.4 Phosphoenolpyruvate carboxykinase (ATP) compare
PFR28_04565 -2.5 -14.3 Protein RarD compare
PFR28_00679 -2.4 -13.2 hypothetical protein conserved
PFR28_04944 -2.4 -6.8 DNA-binding transcriptional regulator NtrC compare
PFR28_01114 -2.2 -8.9 hypothetical protein compare
PFR28_01156 -2.2 -6.6 hypothetical protein compare
PFR28_03420 -2.2 -6.5 hypothetical protein compare
PFR28_03427 -2.1 -9.7 Sensor histidine kinase RcsC compare
PFR28_00680 -2.1 -11.9 hypothetical protein compare
PFR28_04344 -2.1 -4.8 Exopolyphosphatase compare
PFR28_00839 -2.1 -6.1 hypothetical protein compare
PFR28_04425 -2.1 -9.2 2-iminobutanoate/2-iminopropanoate deaminase compare
PFR28_04628 -1.9 -3.5 Thiol:disulfide interchange protein DsbA compare
PFR28_05212 -1.9 -11.1 Sensor histidine kinase RcsC compare
PFR28_03664 -1.8 -3.5 Ribosome-binding ATPase YchF compare
PFR28_03182 -1.7 -5.0 Recombination-associated protein RdgC compare
PFR28_03612 -1.7 -5.1 Cell division protein ZapE compare
PFR28_03209 -1.7 -4.8 Corrinoid adenosyltransferase compare
PFR28_04648 -1.6 -13.7 Citrate transporter conserved
PFR28_05204 -1.6 -3.0 Sulfite reductase [ferredoxin] compare
PFR28_03721 -1.6 -5.7 3-methyl-2-oxobutanoate hydroxymethyltransferase compare
PFR28_03169 -1.6 -10.5 Tail-specific protease compare
PFR28_05201 -1.6 -4.3 Precorrin-6Y C(5,15)-methyltransferase [decarboxylating] compare
PFR28_01113 -1.6 -5.1 DNA topoisomerase 1 compare
PFR28_04103 -1.5 -8.8 Biotin synthase compare
PFR28_03635 -1.5 -6.1 Malate:quinone oxidoreductase compare
PFR28_04936 -1.5 -5.3 Carboxy-terminal processing protease CtpB compare
PFR28_01154 -1.4 -2.3 hypothetical protein compare
PFR28_05071 -1.4 -5.4 D-inositol-3-phosphate glycosyltransferase compare
PFR28_02484 -1.4 -9.2 UTP--glucose-1-phosphate uridylyltransferase compare
PFR28_05207 -1.4 -7.4 Siroheme synthase compare
PFR28_00988 -1.4 -8.6 Sensor histidine kinase RcsC compare
PFR28_01230 -1.4 -4.6 Lon protease compare
PFR28_01378 -1.4 -4.9 Magnesium-chelatase 38 kDa subunit compare
PFR28_03130 -1.4 -3.9 Streptothricin hydrolase compare
PFR28_02838 -1.4 -8.6 Aromatic-amino-acid aminotransferase compare
PFR28_01572 -1.4 -3.5 hypothetical protein compare
PFR28_04633 -1.4 -4.3 Alginate biosynthesis sensor protein KinB compare
PFR28_05078 -1.3 -2.9 hypothetical protein compare
PFR28_04072 -1.3 -3.3 Bifunctional folate synthesis protein compare
PFR28_04064 -1.3 -3.6 Ribosomal RNA small subunit methyltransferase A compare
PFR28_02608 -1.3 -3.0 DNA translocase FtsK compare
PFR28_04030 -1.3 -9.7 hypothetical protein compare
PFR28_03204 -1.2 -7.8 Cobyric acid synthase compare
PFR28_01118 -1.2 -3.0 hypothetical protein compare
PFR28_03203 -1.2 -5.0 Bifunctional adenosylcobalamin biosynthesis protein CobP compare
PFR28_04566 -1.2 -7.8 4-chloro-allylglycine synthase compare
PFR28_04110 -1.2 -9.3 Malate synthase G compare
PFR28_03266 -1.2 -3.1 hypothetical protein compare
PFR28_00098 -1.1 -6.6 Nicotinate-nucleotide pyrophosphorylase [carboxylating] compare
PFR28_03206 -1.1 -7.4 Cobalamin biosynthesis protein CobD compare
PFR28_01083 -1.1 -4.9 putative copper-importing P-type ATPase A compare
PFR28_01060 -1.1 -5.6 HTH-type transcriptional repressor NanR compare
PFR28_03151 -1.1 -1.5 Septum site-determining protein MinC compare
PFR28_03200 -1.1 -4.1 Adenosylcobinamide-GDP ribazoletransferase compare
PFR28_03281 -1.1 -5.3 Arginine N-succinyltransferase subunit beta compare
PFR28_04564 -1.1 -7.7 Aspartate-semialdehyde dehydrogenase compare
PFR28_05139 -1.1 -2.1 hypothetical protein compare
PFR28_03463 -1.1 -2.6 hypothetical protein compare
PFR28_03202 -1.1 -2.6 Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase compare
PFR28_05206 -1.1 -7.4 Precorrin-2 C(20)-methyltransferase compare
PFR28_05006 -1.0 -9.6 Penicillin-binding protein 1A compare
PFR28_04486 -1.0 -6.4 Phosphate import ATP-binding protein PstB compare
PFR28_04113 -1.0 -1.9 DNA polymerase III PolC-type compare
PFR28_03205 -1.0 -4.7 Histidinol-phosphate aminotransferase compare
PFR28_05005 -1.0 -5.9 NADP-dependent malic enzyme compare
PFR28_03837 -1.0 -4.8 Leucine-responsive regulatory protein compare
PFR28_01372 -1.0 -1.7 Precorrin-4 C(11)-methyltransferase compare
PFR28_03208 -1.0 -6.3 Cobyrinate a,c-diamide synthase compare
PFR28_03530 -0.9 -2.0 hypothetical protein compare
PFR28_00425 -0.9 -7.3 Protein-L-isoaspartate O-methyltransferase compare
PFR28_01377 -0.9 -6.0 Aerobic cobaltochelatase subunit CobN compare
PFR28_03627 -0.9 -2.6 SOS response-associated protein YedK compare
PFR28_01081 -0.9 -3.9 hypothetical protein compare
PFR28_04100 -0.9 -5.1 Malonyl-[acyl-carrier protein] O-methyltransferase compare
PFR28_03388 -0.9 -6.5 Quinolinate synthase A compare
PFR28_01003 -0.9 -2.6 hypothetical protein compare
PFR28_04489 -0.9 -5.9 Phosphate-binding protein PstS compare
PFR28_04102 -0.9 -5.5 8-amino-7-oxononanoate synthase compare
PFR28_03625 -0.9 -6.9 Metalloprotease LoiP compare
PFR28_04865 -0.9 -4.7 Glutamate--cysteine ligase compare
PFR28_04521 -0.9 -3.6 HTH-type transcriptional regulator HexR compare
PFR28_05200 -0.9 -3.6 Cobalt-precorrin-5B C(1)-methyltransferase compare
PFR28_00968 -0.9 -1.5 hypothetical protein compare
PFR28_04585 -0.9 -4.0 Chromosome partitioning protein ParA compare
PFR28_04377 -0.9 -4.6 hypothetical protein compare
PFR28_00918 -0.9 -4.4 UDP-N-acetylglucosamine 4,6-dehydratase (inverting) compare
PFR28_00480 -0.8 -3.0 HTH-type transcriptional activator CmpR compare
PFR28_04325 -0.8 -4.1 5-formyltetrahydrofolate cyclo-ligase compare
PFR28_01109 -0.8 -2.7 hypothetical protein compare
PFR28_01616 -0.8 -2.8 HTH-type transcriptional regulator YofA compare
PFR28_05205 -0.8 -3.1 Precorrin-8X methylmutase compare
PFR28_02210 -0.8 -1.4 cAMP-activated global transcriptional regulator CRP compare
PFR28_00276 -0.8 -4.2 S-adenosylmethionine:tRNA ribosyltransferase-isomerase compare
PFR28_04120 -0.8 -1.6 hypothetical protein compare
PFR28_00424 -0.8 -4.6 '5'-nucleotidase SurE' transl_table=11 compare
PFR28_04567 -0.8 -5.8 hypothetical protein compare
PFR28_00525 -0.8 -2.7 Outer membrane lipoprotein SlyB compare
PFR28_05199 -0.8 -2.9 Precorrin-6A reductase compare
PFR28_04903 -0.8 -3.6 hypothetical protein compare
PFR28_05244 -0.8 -6.2 Copper-exporting P-type ATPase compare
PFR28_00271 -0.8 -3.5 hypothetical protein compare
PFR28_01184 -0.8 -5.0 hypothetical protein compare
PFR28_00500 -0.7 -1.6 hypothetical protein compare
PFR28_02613 -0.7 -5.6 ATP-dependent Clp protease ATP-binding subunit ClpA compare
PFR28_03856 -0.7 -1.9 LPS-assembly lipoprotein LptE compare
PFR28_00304 -0.7 -1.5 hypothetical protein compare
PFR28_01376 -0.7 -1.8 hypothetical protein compare
PFR28_00780 -0.7 -1.0 hypothetical protein compare
PFR28_03430 -0.7 -3.8 Arginine biosynthesis bifunctional protein ArgJ compare
PFR28_03657 -0.7 -3.1 Beta-barrel assembly-enhancing protease compare
PFR28_00393 -0.7 -5.5 LL-diaminopimelate aminotransferase compare
PFR28_03412 -0.7 -2.7 Holliday junction ATP-dependent DNA helicase RuvB compare
PFR28_00277 -0.7 -2.1 Queuine tRNA-ribosyltransferase compare
PFR28_03877 -0.7 -3.7 Holin-like protein CidA compare
PFR28_04488 -0.7 -5.7 hypothetical protein compare
PFR28_03598 -0.7 -4.6 Penicillin-binding protein activator LpoA compare
PFR28_03875 -0.7 -0.9 hypothetical protein compare
PFR28_00688 -0.7 -1.0 hypothetical protein compare
PFR28_01313 -0.7 -2.5 hypothetical protein compare
PFR28_00356 -0.7 -3.4 Protein-glutamate methylesterase/protein-glutamine glutaminase compare
PFR28_04569 -0.7 -3.3 HTH-type transcriptional regulator CdhR compare
PFR28_02822 -0.7 -3.5 putative methyltransferase YcgJ compare
PFR28_03244 -0.6 -3.4 Transcriptional regulatory protein PhoP compare
PFR28_04813 -0.6 -1.5 hypothetical protein compare
PFR28_02812 -0.6 -1.9 hypothetical protein compare
PFR28_04230 -0.6 -3.0 Response regulator PleD compare
PFR28_03865 -0.6 -3.8 Endolytic peptidoglycan transglycosylase RlpA compare
PFR28_01369 -0.6 -4.5 Methionine synthase compare
PFR28_03156 -0.6 -4.7 putative M18 family aminopeptidase 2 compare
PFR28_04607 -0.6 -1.2 Organic hydroperoxide resistance protein OhrB compare
PFR28_01265 -0.6 -3.6 (R)-benzylsuccinyl-CoA dehydrogenase compare
PFR28_04262 -0.6 -3.0 Ribosomal RNA small subunit methyltransferase D compare
PFR28_02057 -0.6 -1.4 2-oxo-tetronate isomerase compare
PFR28_00960 -0.6 -5.6 hypothetical protein compare
PFR28_03478 -0.6 -4.5 HTH-type transcriptional regulator MetR compare
PFR28_01933 -0.6 -1.1 Putative tartrate transporter compare
PFR28_00473 -0.6 -1.5 Regulatory protein RecX compare
PFR28_01312 -0.6 -2.0 HTH-type transcriptional regulator NorG compare
PFR28_04931 -0.6 -1.2 hypothetical protein compare
PFR28_01084 -0.6 -2.5 hypothetical protein compare
PFR28_03951 -0.6 -0.9 hypothetical protein compare
PFR28_00503 -0.6 -1.7 Histidine transport ATP-binding protein HisP compare
PFR28_00980 -0.6 -1.1 ATP-dependent RNA helicase DeaD compare
PFR28_02298 -0.6 -1.7 hypothetical protein compare
PFR28_04208 -0.6 -3.1 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase compare
PFR28_02683 -0.6 -2.8 hypothetical protein compare
PFR28_01362 -0.6 -1.5 hypothetical protein compare
PFR28_00837 -0.6 -2.6 hypothetical protein compare
PFR28_04071 -0.6 -0.8 Multifunctional CCA protein compare
PFR28_01375 -0.6 -1.1 hypothetical protein compare
PFR28_04335 -0.6 -3.3 CDP-6-deoxy-L-threo-D-glycero-4-hexulose-3- dehydrase reductase compare


Specific Phenotypes

For 4 genes in this experiment

For carbon source Citric Acid in Pseudomonas sp. RS175

For carbon source Citric Acid across organisms