Experiment set2IT032 for Shewanella loihica PV-4

Compare to:

LB with Paraquat dichloride 10 mg/ml

200 most detrimental genes:

  gene name fitness t score description  
Shew_2049 +5.0 13.1 DNA-binding transcriptional regulator HexR (RefSeq) compare
Shew_3377 +4.5 1.8 twin-arginine translocation protein, TatB subunit (RefSeq) compare
Shew_1298 guaA +3.8 22.5 bifunctional GMP synthase/glutamine amidotransferase protein (RefSeq) compare
Shew_1819 +3.4 6.6 GntR family transcriptional regulator (RefSeq) compare
Shew_1341 +3.2 7.0 anti-sigma-28 factor, FlgM (RefSeq) compare
Shew_3378 +3.1 2.8 Sec-independent protein translocase, TatC subunit (RefSeq) compare
Shew_0570 +3.0 2.4 ubiquinol-cytochrome c reductase, iron-sulfur subunit (RefSeq) compare
Shew_3432 pdhR +2.9 6.0 transcriptional regulator PdhR (RefSeq) compare
Shew_1224 +2.9 19.1 sodium:dicarboxylate symporter (RefSeq) compare
Shew_1058 +2.8 9.7 holo-acyl-carrier-protein synthase (RefSeq) compare
Shew_2000 +2.7 2.9 glyceraldehyde-3-phosphate dehydrogenase (RefSeq) compare
Shew_2572 +2.7 9.6 enoyl-CoA hydratase/isomerase (RefSeq) compare
Shew_1992 +2.7 5.7 hypothetical protein (RefSeq) compare
Shew_1011 +2.6 9.9 citrate transporter (RefSeq) compare
Shew_2642 +2.6 4.7 flavodoxin (RefSeq) compare
Shew_3273 +2.4 9.2 hypothetical protein (RefSeq) compare
Shew_3431 aceE +2.3 14.9 pyruvate dehydrogenase subunit E1 (RefSeq) compare
Shew_1092 +2.3 12.5 amino acid carrier protein (RefSeq) compare
Shew_3681 +2.3 15.6 integral membrane sensor signal transduction histidine kinase (RefSeq) compare
Shew_3682 +2.2 12.0 two component, sigma54 specific, Fis family transcriptional regulator (RefSeq) compare
Shew_1865 +2.2 6.1 phosphoenolpyruvate-protein phosphotransferase (RefSeq) compare
Shew_1078 +2.1 12.5 peptidylprolyl isomerase, FKBP-type (RefSeq) compare
Shew_3498 rpoZ +2.0 2.8 DNA-directed RNA polymerase subunit omega (RefSeq) compare
Shew_1990 +2.0 3.6 heavy metal translocating P-type ATPase (RefSeq) compare
Shew_1657 sucC +2.0 2.2 succinyl-CoA synthetase subunit beta (RefSeq) compare
Shew_1926 +1.9 3.2 transketolase, central region (RefSeq) compare
Shew_3664 +1.9 16.0 alpha-L-glutamate ligase (RefSeq) compare
Shew_1563 +1.9 9.1 isocitrate dehydrogenase, NADP-dependent (RefSeq) compare
Shew_2320 +1.9 7.7 RNA methyltransferase (RefSeq) compare
Shew_3295 +1.9 12.0 AFG1 family ATPase (RefSeq) compare
Shew_3261 +1.8 2.5 thiopurine S-methyltransferase (RefSeq) compare
Shew_0755 +1.7 2.9 fructose-1,6-bisphosphate aldolase (RefSeq) compare
Shew_1987 +1.7 4.1 Cbb3-type cytochrome oxidase component (RefSeq) compare
Shew_0086 +1.7 12.3 electron-transferring-flavoproteindehydrogenase (RefSeq) compare
Shew_1186 +1.7 3.3 transcriptional regulator NrdR (RefSeq) compare
Shew_1985 +1.7 3.2 cytochrome c oxidase, cbb3-type, subunit I (RefSeq) compare
Shew_2584 +1.7 10.4 electron transfer flavoprotein beta-subunit (RefSeq) compare
Shew_1782 +1.6 8.6 MarR family transcriptional regulator (RefSeq) compare
Shew_0220 +1.6 4.7 phosphoglycolate phosphatase (RefSeq) compare
Shew_3710 tdh +1.6 11.9 L-threonine 3-dehydrogenase (RefSeq) compare
Shew_0728 +1.6 10.6 dihydroorotase (RefSeq) compare
Shew_0421 +1.6 1.5 phage shock protein C, PspC (RefSeq) compare
Shew_3487 pyrE +1.6 6.7 orotate phosphoribosyltransferase (RefSeq) compare
Shew_1223 +1.6 1.4 hypothetical protein (RefSeq) compare
Shew_2406 +1.6 2.4 AraC family transcriptional regulator (RefSeq) compare
Shew_3064 gcvT +1.6 10.7 glycine cleavage system aminomethyltransferase T (RefSeq) compare
Shew_0296 +1.6 1.0 heat shock protein Hsp20 (RefSeq) compare
Shew_3383 +1.6 2.7 hypothetical protein (RefSeq) compare
Shew_1437 +1.6 7.4 transcriptional regulator, TyrR (RefSeq) compare
Shew_3716 +1.5 6.1 cytochrome c, class I (RefSeq) compare
Shew_2573 +1.5 9.2 carbamoyl-phosphate synthase L chain, ATP-binding (RefSeq) compare
Shew_3131 +1.5 5.7 poly(A) polymerase (RefSeq) compare
Shew_3063 +1.5 1.9 glycine cleavage system protein H (RefSeq) compare
Shew_2409 +1.5 3.6 short chain dehydrogenase (RefSeq) compare
Shew_1287 +1.5 3.0 hypothetical protein (RefSeq) compare
Shew_0057 +1.5 4.0 cytoplasmic chaperone TorD family protein (RefSeq) compare
Shew_1555 +1.5 2.5 Glu/Leu/Phe/Val dehydrogenase, dimerisation region (RefSeq) compare
Shew_0799 +1.5 2.4 MarR family transcriptional regulator (RefSeq) compare
Shew_3262 +1.4 1.1 hypothetical protein (RefSeq) compare
Shew_1202 +1.4 8.2 (p)ppGpp synthetase I, SpoT/RelA (RefSeq) compare
Shew_1812 +1.4 7.4 23S rRNA m(2)G2445 methyltransferase (RefSeq) compare
Shew_0618 +1.4 1.8 hypothetical protein (RefSeq) compare
Shew_3271 +1.4 8.7 galactokinase (RefSeq) compare
Shew_3709 +1.4 8.7 2-amino-3-ketobutyrate coenzyme A ligase (RefSeq) compare
Shew_0571 +1.3 1.6 cytochrome b/b6 domain-containing protein (RefSeq) compare
Shew_0390 +1.3 1.3 MSHA biogenesis protein MshM (RefSeq) compare
Shew_1925 +1.3 5.1 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) (RefSeq) compare
Shew_3442 +1.3 2.2 hypothetical protein (RefSeq) compare
Shew_2910 +1.3 1.4 hypothetical protein (RefSeq) compare
Shew_2211 +1.3 3.7 phosphoribosylaminoimidazole-succinocarboxamidesynthase (RefSeq) compare
Shew_1810 +1.3 4.4 dihydroorotate dehydrogenase 2 (RefSeq) compare
Shew_0115 +1.3 1.5 hypothetical protein (RefSeq) compare
Shew_1013 +1.3 10.4 aspartate carbamoyltransferase (RefSeq) compare
Shew_3267 +1.3 4.2 sodium/hydrogen exchanger (RefSeq) compare
Shew_1518 +1.3 1.2 hypothetical protein (RefSeq) compare
Shew_2838 carB +1.3 7.9 carbamoyl phosphate synthase large subunit (RefSeq) compare
Shew_0795 +1.3 1.5 hypothetical protein (RefSeq) compare
Shew_0833 +1.3 1.2 hypoxanthine-guanine phosphoribosyltransferase (RefSeq) compare
Shew_2241 +1.2 1.5 hypothetical protein (RefSeq) compare
Shew_2453 +1.2 1.2 hypothetical protein (RefSeq) compare
Shew_0613 +1.2 4.1 cysteine/glutathione ABC transporter membrane/ATP-binding component (RefSeq) compare
Shew_1920 +1.2 4.6 alpha/beta hydrolase fold (RefSeq) compare
Shew_R0076 +1.2 1.1 tRNA-Asn (RefSeq) compare
Shew_2785 +1.2 0.8 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein (RefSeq) compare
Shew_2403 +1.2 1.3 arylesterase (RefSeq) compare
Shew_2389 +1.2 3.2 hypothetical protein (RefSeq) compare
Shew_1714 +1.1 1.7 alpha/beta hydrolase fold (RefSeq) compare
Shew_0854 +1.1 4.0 hypothetical protein (RefSeq) compare
Shew_1867 +1.1 2.8 hypothetical protein (RefSeq) compare
Shew_0782 +1.1 3.0 DNA-binding transcriptional regulator AsnC (RefSeq) compare
Shew_2589 +1.1 1.4 hypothetical protein (RefSeq) compare
Shew_0261 +1.1 0.7 hypothetical protein (RefSeq) compare
Shew_0462 +1.1 0.9 hypothetical protein (RefSeq) compare
Shew_1510 +1.1 1.8 peptidase M28 (RefSeq) compare
Shew_2232 +1.1 2.1 heat shock protein 90 (RefSeq) compare
Shew_2571 +1.1 3.9 propionyl-CoA carboxylase (RefSeq) compare
Shew_3499 +1.1 4.0 bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase (RefSeq) compare
Shew_2236 +1.1 3.2 adenine phosphoribosyltransferase (RefSeq) compare
Shew_0620 +1.1 1.4 ion transport 2 domain-containing protein (RefSeq) compare
Shew_2668 +1.1 4.0 2-nitropropane dioxygenase, NPD (RefSeq) compare
Shew_2666 +1.1 6.5 omega-3 polyunsaturated fatty acid synthase PfaB (RefSeq) compare
Shew_1133 +1.1 4.8 hypothetical protein (RefSeq) compare
Shew_2839 +1.1 7.2 carbamoyl phosphate synthase small subunit (RefSeq) compare
Shew_3311 +1.1 4.6 RNA polymerase factor sigma-54 (RefSeq) compare
Shew_0127 +1.0 2.9 LexA repressor (RefSeq) compare
Shew_3065 +1.0 4.1 UbiH/UbiF/VisC/COQ6 family ubiquinone biosynthesis hydroxylase (RefSeq) compare
Shew_1159 +1.0 2.7 thioesterase superfamily protein (RefSeq) compare
Shew_3537 +1.0 1.7 hypothetical protein (RefSeq) compare
Shew_3683 +1.0 2.4 extracellular solute-binding protein (RefSeq) compare
Shew_1188 +1.0 2.3 riboflavin synthase subunit alpha (RefSeq) compare
Shew_2121 +1.0 1.1 diguanylate cyclase (RefSeq) compare
Shew_2481 +1.0 3.4 porin (RefSeq) compare
Shew_3443 +1.0 1.7 hypothetical protein (RefSeq) compare
Shew_2643 +1.0 1.0 pseudouridylate synthase (RefSeq) compare
Shew_1396 +1.0 2.0 response regulator receiver protein (RefSeq) compare
Shew_1428 +0.9 1.5 fructokinase (RefSeq) compare
Shew_1514 upp +0.9 2.3 uracil phosphoribosyltransferase (RefSeq) compare
Shew_2795 +0.9 3.9 xanthine/uracil/vitamin C permease (RefSeq) compare
Shew_3685 +0.9 3.5 ABC transporter-related protein (RefSeq) compare
Shew_2414 +0.9 2.8 ATP-NAD/AcoX kinase (RefSeq) compare
Shew_2892 +0.9 2.0 major facilitator transporter (RefSeq) compare
Shew_0054 +0.9 3.7 hypothetical protein (RefSeq) compare
Shew_0359 fre +0.9 3.4 FMN reductase (RefSeq) compare
Shew_2639 +0.9 1.6 hypothetical protein (RefSeq) compare
Shew_1210 +0.9 1.9 stationary-phase survival protein SurE (RefSeq) compare
Shew_1357 +0.9 5.3 flagellin domain-containing protein (RefSeq) compare
Shew_1531 grxA +0.9 1.6 glutaredoxin 1 (RefSeq) compare
Shew_0640 +0.9 1.2 TPR repeat-containing protein (RefSeq) compare
Shew_2026 +0.9 1.7 alanine dehydrogenase (RefSeq) compare
Shew_1473 +0.9 2.3 hypothetical protein (RefSeq) compare
Shew_1995 +0.9 0.9 PP-loop domain-containing protein (RefSeq) compare
Shew_0827 +0.9 0.7 peptidyl-prolyl cis-trans isomerase, cyclophilin type (RefSeq) compare
Shew_0843 +0.9 5.6 nitrate/nitrite sensor protein NarQ (RefSeq) compare
Shew_1453 +0.8 2.8 methylated-DNA--protein-cysteinemethyltransferase (RefSeq) compare
Shew_3500 +0.8 1.0 putative endoribonuclease L-PSP (RefSeq) compare
Shew_0678 +0.8 1.8 protoporphyrinogen oxidase (RefSeq) compare
Shew_3786 +0.8 0.7 hypothetical protein (RefSeq) compare
Shew_3622 hslO +0.8 3.8 Hsp33-like chaperonin (RefSeq) compare
Shew_2667 +0.8 5.6 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase, FabA/FabZ (RefSeq) compare
Shew_3693 +0.8 6.0 ADP-heptose--lipooligosaccharide heptosyltransferase III (RefSeq) compare
Shew_2147 +0.8 0.8 hypothetical protein (RefSeq) compare
Shew_2803 +0.8 1.5 DNA-binding transcriptional regulator TorR (RefSeq) compare
Shew_0343 +0.8 0.8 hypothetical protein (RefSeq) compare
Shew_2665 +0.8 5.6 beta-ketoacyl synthase (RefSeq) compare
Shew_2646 +0.8 0.5 hypothetical protein (RefSeq) compare
Shew_1994 +0.8 1.2 universal stress protein UspE (RefSeq) compare
Shew_2664 +0.8 3.8 transcriptional regulator, putative (RefSeq) compare
Shew_1644 +0.8 0.5 DSBA oxidoreductase (RefSeq) compare
Shew_1542 +0.8 2.4 major facilitator transporter (RefSeq) compare
Shew_0136 +0.8 4.0 stearoyl-CoA 9-desaturase (RefSeq) compare
Shew_3069 +0.8 0.8 5-formyltetrahydrofolate cyclo-ligase (RefSeq) compare
Shew_0860 +0.8 0.9 hypothetical protein (RefSeq) compare
Shew_0932 +0.8 0.9 radical SAM domain-containing protein (RefSeq) compare
Shew_3404 +0.8 0.7 NosL family protein (RefSeq) compare
Shew_2903 +0.8 2.1 hypothetical protein (RefSeq) compare
Shew_0616 +0.8 2.0 SH3 domain-containing protein (RefSeq) compare
Shew_0942 +0.8 2.9 RDD domain-containing protein (RefSeq) compare
Shew_3430 +0.8 1.2 pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase (RefSeq) compare
Shew_2890 +0.8 0.8 peptidyl-prolyl cis-trans isomerase, cyclophilin type (RefSeq) compare
Shew_1968 +0.8 0.9 beta-lactamase (RefSeq) compare
Shew_0433 +0.8 1.7 hypothetical protein (RefSeq) compare
Shew_0450 +0.8 3.4 1-acyl-sn-glycerol-3-phosphate acyltransferase (RefSeq) compare
Shew_2395 +0.8 1.3 hypothetical protein (RefSeq) compare
Shew_0056 +0.8 6.1 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein (RefSeq) compare
Shew_2116 +0.8 1.7 AsmA family protein (RefSeq) compare
Shew_3605 +0.8 0.8 cell division ATP-binding protein FtsE (RefSeq) compare
Shew_3188 +0.8 4.1 aromatic amino acid permease (RefSeq) compare
Shew_0580 +0.7 3.4 succinylglutamic semialdehyde dehydrogenase (RefSeq) compare
Shew_1713 +0.7 0.9 3-oxoacyl-(acyl carrier protein) synthase III (RefSeq) compare
Shew_3742 +0.7 1.8 flagellar basal body-associated protein FliL-like protein (RefSeq) compare
Shew_1264 +0.7 0.9 UvrD/REP helicase (RefSeq) compare
Shew_1962 +0.7 1.3 D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase (RefSeq) compare
Shew_2537 +0.7 1.2 AraC family transcriptional regulator (RefSeq) compare
Shew_3568 +0.7 3.1 cation diffusion facilitator family transporter (RefSeq) compare
Shew_0938 +0.7 1.7 TonB-dependent receptor (RefSeq) compare
Shew_0584 +0.7 0.7 hypothetical protein (RefSeq) compare
Shew_2400 +0.7 2.2 hypothetical protein (RefSeq) compare
Shew_3625 +0.7 1.1 sodium:dicarboxylate symporter (RefSeq) compare
Shew_0581 +0.7 3.6 hypothetical protein (RefSeq) compare
Shew_3247 +0.7 0.5 hypothetical protein (RefSeq) compare
Shew_3268 +0.7 1.4 hypothetical protein (RefSeq) compare
Shew_3686 +0.7 4.9 molybdopterin-guanine dinucleotide biosynthesis protein A (RefSeq) compare
Shew_3598 +0.7 0.5 AsnC family transcriptional regulator (RefSeq) compare
Shew_2531 +0.7 2.9 LysR family transcriptional regulator (RefSeq) compare
Shew_1705 +0.7 0.9 hypothetical protein (RefSeq) compare
Shew_1575 +0.7 2.0 uridine kinase (RefSeq) compare
Shew_2559 +0.7 1.9 malate synthase (RefSeq) compare
Shew_2059 +0.7 2.5 hypothetical protein (RefSeq) compare
Shew_1678 +0.7 0.8 hypothetical protein (RefSeq) compare
Shew_1898 +0.7 0.8 ApbE family lipoprotein (RefSeq) compare
Shew_2073 +0.7 0.5 lactoylglutathione lyase (RefSeq) compare
Shew_0396 +0.7 0.7 methylation site containing protein (RefSeq) compare
Shew_0846 +0.7 1.0 nitrogen regulatory protein P-II (RefSeq) compare
Shew_2570 +0.7 5.1 acyl-CoA dehydrogenase domain-containing protein (RefSeq) compare
Shew_R0049 +0.7 3.6 tRNA-Pro (RefSeq) compare
Shew_1181 +0.7 1.6 PepSY-associated TM helix domain-containing protein (RefSeq) compare
Shew_1535 +0.7 2.0 fumarylacetoacetate (FAA) hydrolase (RefSeq) compare
Shew_1878 +0.7 2.3 2-nitropropane dioxygenase, NPD (RefSeq) compare
Shew_0388 +0.7 2.1 MSHA biogenesis protein MshK (RefSeq) compare
Shew_1015 +0.7 2.4 Cl- channel, voltage-gated family protein (RefSeq) compare


Specific Phenotypes

For 1 genes in this experiment

For stress Paraquat dichloride in Shewanella loihica PV-4

For stress Paraquat dichloride across organisms