Experiment set1S415 for Escherichia coli ECRC62

Compare to:

Bas61

200 most detrimental genes:

  gene name fitness t score description  
BNILDI_19355 flgD +2.5 5.4 flagellar hook assembly protein FlgD conserved
BNILDI_19345 flgF +2.1 4.0 flagellar basal-body rod protein FlgF compare
BNILDI_15130 fliG +2.0 5.6 flagellar motor switch protein FliG compare
BNILDI_15135 fliF +1.9 5.1 flagellar M-ring protein FliF compare
BNILDI_15335 flhC +1.8 4.7 flagellar transcriptional regulator FlhC compare
BNILDI_15125 fliH +1.7 2.2 flagellar assembly protein FliH compare
BNILDI_15120 fliI +1.7 1.7 flagellum-specific ATP synthase FliI compare
BNILDI_19035 bluR +1.7 2.3 DNA-binding transcriptional repressor BluR compare
BNILDI_15075 fliR +1.6 2.2 flagellar type III secretion system protein FliR compare
BNILDI_19340 flgG +1.6 5.8 flagellar basal-body rod protein FlgG compare
BNILDI_19350 flgE +1.6 6.1 flagellar hook protein FlgE compare
BNILDI_19370 flgA +1.6 5.3 flagellar basal body P-ring formation protein FlgA compare
BNILDI_15100 fliM +1.5 2.7 flagellar motor switch protein FliM compare
BNILDI_15115 fliJ +1.5 4.0 flagella biosynthesis chaperone FliJ compare
BNILDI_15080 fliQ +1.5 2.8 flagellar biosynthesis protein FliQ compare
BNILDI_19360 flgC +1.4 2.7 flagellar basal body rod protein FlgC compare
BNILDI_19325 flgJ +1.4 4.5 flagellar assembly peptidoglycan hydrolase FlgJ compare
BNILDI_15770 prc +1.4 10.5 carboxy terminal-processing peptidase compare
BNILDI_15400 flhA +1.4 6.1 flagellar biosynthesis protein FlhA compare
BNILDI_03595 cspA +1.4 1.5 Major cold shock protein compare
BNILDI_13595 yfaH +1.3 1.6 Putative protein YfaH compare
BNILDI_15395 flhB +1.3 4.5 flagellar biosynthesis protein FlhB compare
BNILDI_15140 fliE +1.3 2.0 flagellar hook-basal body complex protein FliE compare
BNILDI_03100 mngR +1.2 2.0 GntR family transcriptional regulator compare
BNILDI_19545 cgsF +1.2 2.3 curli production assembly/transport protein CsgF compare
BNILDI_15090 fliO +1.2 4.1 flagellar type III secretion system protein FliO compare
BNILDI_18870 ldcA +1.2 3.4 muramoyltetrapeptide carboxypeptidase compare
BNILDI_11900 pdxJ +1.1 1.1 pyridoxine 5'-phosphate synthase compare
BNILDI_15065 dsrB +1.1 2.1 protein DsrB compare
BNILDI_17385 ydeO +1.1 3.5 acid stress response transcriptional regulator YdeO compare
BNILDI_07870 hpcD +1.0 0.9 5-carboxymethyl-2-hydroxymuconate Delta-isomerase compare
BNILDI_03430 bcsR +1.0 1.6 cellulose biosynthesis protein BcsR compare
BNILDI_19330 flgI +1.0 3.1 flagellar basal body P-ring protein FlgI compare
BNILDI_19900 yccX +1.0 0.9 acylphosphatase compare
BNILDI_19365 flgB +1.0 0.9 flagellar basal body rod protein FlgB compare
BNILDI_05220 yihD +1.0 2.1 Protein YihD compare
BNILDI_12780 +1.0 1.2 flxA-like family protein compare
BNILDI_18575 +1.0 1.3 hypothetical protein compare
BNILDI_08575 fruL +1.0 1.7 Putative fruR/shl operon leader peptide compare
BNILDI_15095 fliN +0.9 2.7 flagellar motor switch protein FliN compare
BNILDI_07660 fimE +0.9 2.8 type 1 fimbria switch DNA invertase FimE compare
BNILDI_19315 flgL +0.9 3.8 flagellar hook-associated protein FlgL compare
BNILDI_11265 ygaP +0.9 0.7 thiosulfate sulfurtransferase YgaP compare
BNILDI_00030 ykgH +0.9 2.3 Uncharacterized protein YkgH compare
BNILDI_15110 fliK +0.9 3.0 flagellar hook length control protein FliK compare
BNILDI_07580 +0.9 1.1 biofilm development YmgB/AriR family protein compare
BNILDI_15085 fliP +0.9 3.4 flagellar type III secretion system pore protein FliP compare
BNILDI_14525 dcd +0.9 2.8 dCTP deaminase compare
BNILDI_18165 ycjW +0.9 1.7 Uncharacterized HTH-type transcriptional regulator YcjW compare
BNILDI_23145 cynS +0.9 2.6 cyanase compare
BNILDI_07560 +0.9 4.4 PfkB family carbohydrate kinase compare
BNILDI_07020 yjfJ +0.8 2.2 Uncharacterized protein YjfJ compare
BNILDI_22615 glnK +0.8 2.9 P-II family nitrogen regulator compare
BNILDI_01925 zapG +0.8 1.3 Z-ring associated protein ZapG compare
BNILDI_09160 skp +0.8 0.8 molecular chaperone Skp compare
BNILDI_13765 napB +0.8 1.3 nitrate reductase cytochrome c-type subunit compare
BNILDI_13680 rcsB +0.8 1.2 transcriptional regulator RcsB compare
BNILDI_10860 rpoS +0.8 4.5 RNA polymerase sigma factor RpoS compare
BNILDI_09505 +0.8 1.5 hypothetical protein compare
BNILDI_13510 arnT +0.8 0.7 lipid IV(A) 4-amino-4-deoxy-L-arabinosyltransferase compare
BNILDI_06360 +0.8 1.0 hypothetical protein compare
BNILDI_20450 cspD +0.8 1.8 cold shock-like protein CspD compare
BNILDI_13310 yfcF +0.8 2.2 glutathione transferase compare
BNILDI_03695 hycB +0.8 1.4 electron transporter compare
BNILDI_12940 frc +0.8 1.9 formyl-CoA transferase compare
BNILDI_12200 +0.7 2.8 Protein compare
BNILDI_06545 phnO +0.7 1.2 aminoalkylphosphonate N-acetyltransferase compare
BNILDI_15145 yedK +0.7 1.5 Abasic site processing protein YedK compare
BNILDI_05680 +0.7 1.2 DsORF-f3 compare
BNILDI_07140 +0.7 1.2 TRAP transporter small permease compare
BNILDI_08525 sgrT +0.7 1.1 Putative inhibitor of glucose uptake transporter SgrT compare
BNILDI_10200 +0.7 1.6 hypothetical protein compare
BNILDI_08555 leuL +0.7 1.0 leu operon leader peptide compare
BNILDI_13685 rcsD +0.7 3.9 phosphotransferase RcsD compare
BNILDI_10895 otnC +0.7 2.4 aldolase compare
BNILDI_17900 paaJ +0.7 1.5 bifunctional 3-oxoadipyl-CoA/3-oxo-5,6-dehydrosuberyl-CoA thiolase compare
BNILDI_02910 yrhB +0.7 1.7 Uncharacterized protein YrhB compare
BNILDI_16270 chbA +0.7 2.1 PTS N,N'-diacetylchitobiose transporter subunit IIA compare
BNILDI_15705 yobA +0.7 0.7 CopC domain-containing protein YobA compare
BNILDI_18880 +0.7 0.8 hypothetical protein compare
BNILDI_15190 fliA +0.7 2.4 RNA polymerase sigma factor FliA compare
BNILDI_11455 +0.7 1.0 sporadically distributed , TIGR04141 family protein compare
BNILDI_13665 rcsC +0.7 3.2 two-component system sensor histidine kinase RcsC compare
BNILDI_16560 sufA +0.7 1.1 Fe-S cluster assembly scaffold SufA compare
BNILDI_11430 +0.7 0.8 hypothetical protein compare
BNILDI_04205 ivbL +0.7 0.7 ilvB operon leader peptide IvbL compare
BNILDI_10545 fucA +0.7 1.4 L-fuculose-phosphate aldolase compare
BNILDI_00275 prfH +0.7 2.0 peptide chain release factor H compare
BNILDI_22235 ybcI +0.7 2.5 Inner membrane protein YbcI compare
BNILDI_07720 yjiC +0.6 1.7 Uncharacterized protein YjiC compare
BNILDI_04030 slmA +0.6 1.8 nucleoid occlusion factor SlmA compare
BNILDI_00495 tnpB +0.6 0.8 IS66 family insertion sequence element accessory protein TnpB compare
BNILDI_19745 cbpM +0.6 2.4 chaperone modulator CbpM compare
BNILDI_07730 iraD +0.6 2.2 anti-adapter protein IraD compare
BNILDI_21000 moaB +0.6 1.3 molybdenum cofactor biosynthesis protein B compare
BNILDI_21905 ybdO +0.6 1.7 Uncharacterized HTH-type transcriptional regulator YbdO compare
BNILDI_04350 yidB +0.6 1.6 Uncharacterized protein YidB compare
BNILDI_03335 gadX +0.6 2.5 acid resistance transcriptional activator GadX compare
BNILDI_07735 hypT +0.6 1.2 hypochlorite stress DNA-binding transcriptional regulator HypT compare
BNILDI_21835 +0.6 0.7 citrate lyase acyl carrier protein 1 compare
BNILDI_11975 glnB +0.6 1.5 nitrogen regulatory protein P-II compare
BNILDI_05030 yigI +0.6 1.3 thioesterase family protein compare
BNILDI_10270 yqeH +0.6 0.5 Uncharacterized protein YqeH compare
BNILDI_00320 dinJ +0.6 0.9 type II toxin-antitoxin system antitoxin DinJ compare
BNILDI_07595 +0.6 1.6 hypothetical protein compare
BNILDI_03840 yibL +0.6 0.6 YibL family ribosome-associated protein compare
BNILDI_16970 folM +0.6 1.7 dihydromonapterin reductase compare
BNILDI_16000 yeaL +0.6 0.6 UPF0756 membrane protein CKO_01811 compare
BNILDI_21470 speFL +0.6 0.6 Leader peptide SpeFL compare
BNILDI_12615 +0.6 1.0 Ethanolamine ammonia lyase large subunit compare
BNILDI_12450 arsC +0.6 0.7 ArsC family reductase compare
BNILDI_11275 yqaE +0.6 1.4 UPF0057 membrane protein YqaE compare
BNILDI_00535 +0.6 2.2 type II toxin-antitoxin system RelE/ParE family toxin compare
BNILDI_09525 zorB +0.6 2.7 Zorya protein ZorB compare
BNILDI_22145 essD +0.6 1.9 phage lysis protein EssD compare
BNILDI_10580 syd +0.6 2.8 SecY-interacting protein compare
BNILDI_12320 hyfI +0.6 1.1 hydrogenase 4 catalytic subunit HyfI compare
BNILDI_18235 pspC +0.6 2.2 envelope stress response membrane protein PspC compare
BNILDI_12660 yfeY +0.6 1.3 RpoE-regulated lipoprotein compare
BNILDI_21420 ybfC +0.6 1.1 Uncharacterized protein YbfC compare
BNILDI_01540 yhbQ +0.6 1.1 DNA damage response exodeoxyribonuclease YhbQ compare
BNILDI_19175 comR +0.6 1.7 TetR family copper-responsive transcriptional repressor ComR compare
BNILDI_10915 pphB +0.6 1.5 protein-serine/threonine phosphatase compare
BNILDI_15735 yebW +0.6 1.2 Uncharacterized protein YebW compare
BNILDI_03960 rfaY +0.5 2.6 lipopolysaccharide core heptose(II) kinase RfaY compare
BNILDI_10925 +0.5 1.7 hypothetical protein compare
BNILDI_09645 mutY +0.5 2.1 A/G-specific adenine glycosylase compare
BNILDI_18105 ynaI +0.5 1.7 low conductance mechanosensitive channel YnaI compare
BNILDI_20635 rcdA +0.5 0.8 DNA-binding transcriptional regulator RcdA compare
BNILDI_09580 +0.5 2.4 hypothetical protein compare
BNILDI_21805 cspE +0.5 0.9 transcription antiterminator/RNA stability regulator CspE compare
BNILDI_00405 +0.5 3.0 contractile injection system protein, VgrG/Pvc8 family compare
BNILDI_08035 deoC +0.5 0.6 deoxyribose-phosphate aldolase compare
BNILDI_02500 pabA +0.5 2.1 aminodeoxychorismate synthase component 2 compare
BNILDI_10930 ygbA +0.5 1.4 nitrous oxide-stimulated promoter family protein compare
BNILDI_15765 proQ +0.5 1.9 RNA chaperone ProQ compare
BNILDI_01275 yhaH +0.5 1.6 Inner membrane protein YhaH compare
BNILDI_08125 creA +0.5 2.2 protein CreA compare
BNILDI_10100 ssnA +0.5 2.8 putative aminohydrolase SsnA compare
BNILDI_12930 ypdI +0.5 0.9 colanic acid biosynthesis lipoprotein YpdI compare
BNILDI_03235 arsR +0.5 1.6 As(III)-sensing metalloregulatory transcriptional repressor ArsR compare
BNILDI_14980 hiuH +0.5 1.5 hydroxyisourate hydrolase compare
BNILDI_05005 corA +0.5 0.8 magnesium/cobalt transporter CorA compare
BNILDI_21670 rihA +0.5 2.6 pyrimidine-specific ribonucleoside hydrolase RihA compare
BNILDI_01780 lptC +0.5 1.4 LPS export ABC transporter periplasmic protein LptC compare
BNILDI_15330 flhD +0.5 1.2 flagellar transcriptional regulator FlhD compare
BNILDI_00865 ygiZ +0.5 0.9 Inner membrane protein YgiZ compare
BNILDI_16845 rsxG +0.5 1.3 electron transport complex subunit RsxG compare
BNILDI_06480 nrfF +0.5 1.2 heme lyase NrfEFG subunit NrfF compare
BNILDI_12965 evgA +0.5 1.2 acid-sensing system DNA-binding response regulator EvgA compare
BNILDI_08920 panC +0.5 1.1 pantoate--beta-alanine ligase compare
BNILDI_11270 ygaV +0.5 1.2 putative HTH-type transcriptional regulator YgaV compare
BNILDI_06200 yjbF +0.5 2.4 Uncharacterized lipoprotein YjbF compare
BNILDI_00875 ygiN +0.5 1.1 putative quinol monooxygenase YgiN compare
BNILDI_08940 yadL +0.5 1.7 fimbrial-like protein YadL compare
BNILDI_13540 ais +0.5 1.9 Lipopolysaccharide core heptose(II)-phosphate phosphatase compare
BNILDI_11405 +0.5 0.7 Cell wall-binding protein compare
BNILDI_06185 pgi +0.5 3.2 glucose-6-phosphate isomerase compare
BNILDI_17270 tam +0.5 1.5 trans-aconitate 2-methyltransferase compare
BNILDI_07330 cybC +0.5 1.3 cytochrome b562 compare
BNILDI_13775 ccmA +0.5 1.2 cytochrome c biogenesis heme-transporting ATPase CcmA compare
BNILDI_11780 yfiM +0.5 1.0 YfiM family lipoprotein compare
BNILDI_20850 glnQ +0.5 0.7 glutamine ABC transporter ATP-binding protein GlnQ compare
BNILDI_12635 eutR +0.5 2.7 HTH-type transcriptional regulator EutR compare
BNILDI_13300 folX +0.5 1.0 dihydroneopterin triphosphate 2'-epimerase compare
BNILDI_18930 hlyE +0.5 1.1 hemolysin HlyE compare
BNILDI_10870 ecdB +0.5 1.4 putative UbiX-like flavin prenyltransferase compare
BNILDI_08175 yaaX +0.5 1.9 Uncharacterized protein YaaX compare
BNILDI_16490 ydiP +0.5 1.1 Uncharacterized HTH-type transcriptional regulator YdiP compare
BNILDI_22130 bor +0.5 1.7 serum resistance lipoprotein Bor compare
BNILDI_16620 ydhW +0.5 2.2 YdhW family putative oxidoreductase system protein compare
BNILDI_22755 yajQ +0.5 1.5 nucleotide binding protein YajQ compare
BNILDI_21160 gpmA +0.5 1.0 2,3-diphosphoglycerate-dependent phosphoglycerate mutase compare
BNILDI_12710 cysA +0.5 1.0 sulfate/thiosulfate ABC transporter ATP-binding protein CysA compare
BNILDI_09465 +0.5 2.1 AlpA family transcriptional regulator compare
BNILDI_15175 fliS +0.5 1.9 flagellar export chaperone FliS compare
BNILDI_19525 csgB +0.5 1.4 curlin minor subunit CsgB compare
BNILDI_11805 trxC +0.5 2.3 thioredoxin TrxC compare
BNILDI_21185 nadA +0.5 2.1 quinolinate synthase NadA compare
BNILDI_10905 ltnD +0.5 1.2 L-threonate dehydrogenase compare
BNILDI_08235 mokC +0.5 1.1 type I toxin-antitoxin system toxin MokC compare
BNILDI_21260 ybgE +0.5 1.1 cyd operon protein YbgE compare
BNILDI_00255 crl +0.5 2.1 sigma factor-binding protein Crl compare
BNILDI_16890 malY +0.5 2.5 bifunctional maltose regulon transcriptional repressor/cystathionine beta-lyase MalY compare
BNILDI_21740 rsfS +0.5 1.7 ribosome silencing factor compare
BNILDI_19505 ymdB +0.5 1.4 O-acetyl-ADP-ribose deacetylase compare
BNILDI_16665 ydhQ +0.5 1.8 Uncharacterized protein YdhQ compare
BNILDI_17210 marA +0.5 1.6 MDR efflux pump AcrAB transcriptional activator MarA compare
BNILDI_17490 +0.4 2.1 3-hydroxybutyryl-CoA dehydrogenase compare
BNILDI_20165 ssuB +0.4 1.5 aliphatic sulfonates ABC transporter ATP-binding protein compare
BNILDI_19000 ymgF +0.4 0.9 Inner membrane protein YmgF compare
BNILDI_20025 fimA +0.4 2.1 fimbrial protein compare
BNILDI_10850 pcm +0.4 2.1 protein-L-isoaspartate O-methyltransferase compare
BNILDI_03365 yhjD +0.4 2.2 inner membrane protein YhjD compare
BNILDI_04050 yicC +0.4 1.4 UPF0701 protein YicC compare
BNILDI_13720 mqo +0.4 2.6 malate dehydrogenase (quinone) compare
BNILDI_14120 yohF +0.4 1.4 SDR family oxidoreductase compare
BNILDI_12550 eutH +0.4 1.9 ethanolamine utilization protein EutH compare
BNILDI_04260 yidL +0.4 2.0 Uncharacterized HTH-type transcriptional regulator YidL compare
BNILDI_15410 yecT +0.4 1.4 Uncharacterized protein YecT compare


Specific Phenotypes

For 7 genes in this experiment

For phage MOI 10 in Escherichia coli ECRC62

For phage MOI 10 across organisms