Experiment set1IT027 for Cupriavidus basilensis FW507-4G11

Compare to:

R2A with Doxycycline hyclate 0.0001 mg/ml

200 most important genes:

  gene name fitness t score description  
RR42_RS01255 -6.6 -6.4 lauroyl acyltransferase compare
RR42_RS06255 -5.9 -3.7 lipoprotein compare
RR42_RS04325 -5.6 -3.8 membrane protein compare
RR42_RS09015 -5.3 -3.7 trigger factor compare
RR42_RS13125 -4.9 -4.7 pyrrolo-quinoline quinone compare
RR42_RS18970 -4.9 -13.1 toluene ABC transporter ATP-binding protein compare
RR42_RS32250 -4.8 -16.0 ABC transporter compare
RR42_RS01260 -4.8 -6.0 lauroyl acyltransferase compare
RR42_RS18945 -4.8 -6.6 toluene tolerance protein compare
RR42_RS18965 -4.7 -13.2 ABC transporter permease compare
RR42_RS18960 -4.7 -12.1 ABC transporter substrate-binding protein compare
RR42_RS17565 -4.6 -15.8 LysR family transcriptional regulator compare
RR42_RS20650 -4.5 -11.6 multidrug efflux RND transporter permease subunit compare
RR42_RS07555 -4.4 -3.0 potassium transporter Kup compare
RR42_RS17560 -4.4 -5.1 Fur family transcriptional regulator compare
RR42_RS06345 -4.3 -4.8 hypothetical protein compare
RR42_RS04405 -4.3 -9.9 cyanophycin synthetase compare
RR42_RS18270 -4.3 -5.0 murein transglycosylase compare
RR42_RS01785 -4.2 -3.6 PTS fructose transporter subunit IIA compare
RR42_RS18855 -4.2 -2.9 preprotein translocase compare
RR42_RS36270 -4.1 -13.8 patatin conserved
RR42_RS20450 -4.1 -9.5 16S rRNA methyltransferase conserved
RR42_RS18850 -4.0 -3.8 preprotein translocase subunit TatC compare
RR42_RS01795 -3.9 -11.8 phosphoenolpyruvate-protein phosphotransferase compare
RR42_RS02500 -3.8 -2.3 TetR family transcriptional regulator compare
RR42_RS36665 -3.8 -9.6 hypothetical protein conserved
RR42_RS04895 -3.8 -10.9 serine/threonine protein phosphatase compare
RR42_RS17105 -3.7 -12.1 Clp protease ClpX compare
RR42_RS06585 -3.7 -18.8 GTP pyrophosphokinase compare
RR42_RS02775 -3.7 -2.8 molecular chaperone SurA compare
RR42_RS02705 -3.6 -2.3 Holliday junction DNA helicase RuvA compare
RR42_RS01820 -3.6 -6.8 peptidase S41 compare
RR42_RS15795 -3.6 -6.4 spore coat protein compare
RR42_RS13030 -3.6 -16.8 ATP-dependent helicase conserved
RR42_RS04970 -3.6 -12.2 aspartyl beta-hydroxylase compare
RR42_RS18950 -3.6 -8.7 hypothetical protein compare
RR42_RS14055 -3.5 -3.4 elongation factor 4 compare
RR42_RS16950 -3.5 -7.3 CDP-6-deoxy-delta-3,4-glucoseen reductase compare
RR42_RS15020 -3.4 -7.8 (2Fe-2S)-binding protein compare
RR42_RS32235 -3.4 -7.5 hopanoid biosynthesis associated radical SAM protein HpnH compare
RR42_RS32240 -3.2 -8.2 ABC transporter compare
RR42_RS32245 -3.2 -11.7 RND transporter compare
RR42_RS15895 -3.2 -7.9 uroporphyrinogen III methyltransferase compare
RR42_RS04420 -3.2 -7.2 required for efflux of an amino acid polymer (from data) compare
RR42_RS18420 -3.2 -7.8 hypothetical protein compare
RR42_RS04700 -3.2 -1.6 ribonuclease G compare
RR42_RS04415 -3.2 -9.8 ABC transporter compare
RR42_RS00445 -3.1 -12.2 membrane protein compare
RR42_RS19885 -3.1 -1.9 aminoglycoside transporter compare
RR42_RS04410 -3.0 -7.2 cyanophycin synthetase compare
RR42_RS06580 -3.0 -6.5 aminoacrylate peracid reductase compare
RR42_RS14790 -2.9 -7.3 cobalamin biosynthesis protein CobD compare
RR42_RS02045 -2.9 -10.6 GTPase compare
RR42_RS02785 -2.9 -3.9 dimethyladenosine transferase compare
RR42_RS33475 -2.9 -3.8 CopG family transcriptional regulator compare
RR42_RS13935 -2.9 -3.6 hemin transporter compare
RR42_RS15890 -2.8 -6.3 heme biosynthesis protein HemY compare
RR42_RS22585 -2.8 -2.5 MarR family transcriptional regulator compare
RR42_RS25785 -2.8 -3.4 TetR family transcriptional regulator compare
RR42_RS14965 -2.8 -5.4 hypothetical protein compare
RR42_RS21040 -2.7 -1.4 hypothetical protein compare
RR42_RS18310 -2.6 -2.2 indole-3-glycerol-phosphate synthase compare
RR42_RS35900 -2.5 -8.8 hypothetical protein compare
RR42_RS32260 -2.5 -8.0 squalene--hopene cyclase compare
RR42_RS17055 -2.5 -7.2 LuxR family transcriptional regulator compare
RR42_RS03170 -2.5 -2.7 hypothetical protein compare
RR42_RS15640 -2.4 -1.2 hypothetical protein compare
RR42_RS14365 -2.4 -2.3 N-(5'-phosphoribosyl)anthranilate isomerase compare
RR42_RS12590 -2.3 -1.2 50S ribosomal protein L9 compare
RR42_RS01270 -2.3 -10.6 3-deoxy-D-manno-oct-2-ulosonic acid (Kdo) hydroxylase compare
RR42_RS28935 -2.3 -7.6 hypothetical protein compare
RR42_RS17060 -2.3 -14.0 histidine kinase compare
RR42_RS15790 -2.3 -6.7 aminotransferase class III compare
RR42_RS07590 -2.2 -4.3 pseudouridine synthase compare
RR42_RS03565 -2.2 -2.5 hypothetical protein compare
RR42_RS03095 -2.2 -1.9 succinyl-CoA synthetase subunit beta compare
RR42_RS00115 -2.2 -1.7 hypothetical protein compare
RR42_RS00830 -2.2 -6.6 cell division protein FtsN compare
RR42_RS02035 -2.2 -8.0 hypothetical protein compare
RR42_RS22455 -2.2 -11.3 2-aminoethylphosphonate aminotransferase compare
RR42_RS15465 -2.1 -2.5 TonB-dependent receptor compare
RR42_RS03560 -2.1 -2.0 hypothetical protein compare
RR42_RS20655 -2.1 -3.8 multidrug transporter compare
RR42_RS24510 -2.1 -1.4 hypothetical protein compare
RR42_RS32740 -2.1 -1.3 enoyl-CoA hydratase compare
RR42_RS16240 -2.1 -1.3 cobalamin biosynthesis protein CbiX compare
RR42_RS32520 -2.1 -2.8 cytochrome C compare
RR42_RS14495 -2.1 -7.4 hypothetical protein compare
RR42_RS09300 -2.1 -2.0 aromatic ring-opening dioxygenase LigB compare
RR42_RS18985 -2.1 -6.7 glutamate synthase compare
RR42_RS17865 -2.0 -6.6 N-acetyl-anhydromuranmyl-L-alanine amidase compare
RR42_RS12015 -2.0 -2.5 dihydrolipoamide acyltransferase compare
RR42_RS21220 -2.0 -2.5 iron transporter FeoB compare
RR42_RS28595 -2.0 -12.1 squalene--hopene cyclase compare
RR42_RS22425 -2.0 -4.6 CDP-alcohol phosphatidyltransferase compare
RR42_RS11770 -2.0 -1.3 cyclase compare
RR42_RS13065 -2.0 -7.5 ribonuclease R compare
RR42_RS34535 -1.9 -2.1 membrane protein compare
RR42_RS17235 -1.9 -6.3 poly(A) polymerase compare
RR42_RS22450 -1.9 -5.0 phosphonopyruvate decarboxylase compare
RR42_RS32225 -1.9 -7.9 NAD-dependent dehydratase compare
RR42_RS07310 -1.9 -5.2 hypothetical protein compare
RR42_RS23565 -1.9 -1.1 flagellar motor switch protein G compare
RR42_RS05905 -1.8 -2.2 hypothetical protein compare
RR42_RS15470 -1.8 -1.6 biopolymer transporter ExbD compare
RR42_RS15475 -1.8 -6.2 protein tolQ compare
RR42_RS01990 -1.8 -2.0 methyltransferase compare
RR42_RS20440 -1.8 -1.5 histidine kinase compare
RR42_RS22445 -1.8 -9.1 phosphoenolpyruvate phosphomutase compare
RR42_RS36265 -1.8 -3.9 esterase compare
RR42_RS15460 -1.8 -4.5 translocation protein TolB compare
RR42_RS09085 -1.8 -1.5 C4-dicarboxylate ABC transporter permease compare
RR42_RS06355 -1.8 -4.7 Fe-S cluster assembly protein HesB compare
RR42_RS29335 -1.8 -1.5 integrase compare
RR42_RS22435 -1.8 -6.8 membrane protein compare
RR42_RS29490 -1.7 -2.6 toxin HipA compare
RR42_RS28955 -1.7 -5.5 transcriptional regulator compare
RR42_RS18140 -1.7 -1.4 MarR family transcriptional regulator compare
RR42_RS06575 -1.7 -3.8 alpha/beta hydrolase compare
RR42_RS37240 -1.7 -1.5 hypothetical protein compare
RR42_RS15525 -1.7 -1.3 hypothetical protein compare
RR42_RS03570 -1.7 -3.0 membrane protein compare
RR42_RS14355 -1.7 -5.7 DNA methylase N-4 compare
RR42_RS06740 -1.6 -2.0 hypothetical protein compare
RR42_RS10415 -1.6 -1.2 hypothetical protein compare
RR42_RS15775 -1.6 -4.6 N-acetylneuraminate synthase compare
RR42_RS20205 -1.6 -2.7 chromosome partitioning protein compare
RR42_RS15770 -1.6 -4.0 hypothetical protein compare
RR42_RS34610 -1.6 -2.7 hydroxyacid dehydrogenase compare
RR42_RS19555 -1.6 -1.7 hypothetical protein compare
RR42_RS25530 -1.6 -5.4 TetR family transcriptional regulator compare
RR42_RS06250 -1.6 -2.2 dihydrodipicolinate synthase compare
RR42_RS31900 -1.6 -3.4 short-chain dehydrogenase compare
RR42_RS01210 -1.6 -3.8 n-acetyl-gamma-glutamyl-phosphate reductase compare
RR42_RS05420 -1.6 -5.4 membrane protein compare
RR42_RS15015 -1.6 -0.9 exodeoxyribonuclease VII small subunit compare
RR42_RS05485 -1.6 -1.2 polynucleotide phosphorylase/polyadenylase compare
RR42_RS15800 -1.6 -4.2 aldo/keto reductase compare
RR42_RS06630 -1.5 -1.6 integration host factor subunit alpha compare
RR42_RS08000 -1.5 -1.3 hypothetical protein compare
RR42_RS02310 -1.5 -2.8 NADPH-dependent 7-cyano-7-deazaguanine reductase compare
RR42_RS07150 -1.5 -1.3 hypothetical protein compare
RR42_RS04890 -1.5 -3.4 ribonuclease PH compare
RR42_RS18955 -1.5 -5.0 ABC transporter compare
RR42_RS34215 -1.5 -1.2 ferredoxin compare
RR42_RS26350 -1.5 -2.1 bleomycin resistance protein compare
RR42_RS15710 -1.5 -6.0 LPS biosynthesis protein compare
RR42_RS22440 -1.5 -4.1 ADP-glucose pyrophosphorylase compare
RR42_RS17390 -1.5 -5.1 ATP-dependent DNA helicase RecG compare
RR42_RS15455 -1.4 -3.2 membrane protein compare
RR42_RS05775 -1.4 -2.8 hypothetical protein compare
RR42_RS33180 -1.4 -5.9 hypothetical protein compare
RR42_RS20855 -1.4 -5.0 cold-shock protein compare
RR42_RS20385 -1.4 -7.2 methyltransferase compare
RR42_RS32230 -1.4 -4.7 4-hydroxy-3-methylbut-2-enyl diphosphate reductase compare
RR42_RS10400 -1.4 -2.2 hypothetical protein compare
RR42_RS03890 -1.4 -3.2 paraquat-inducible protein A compare
RR42_RS03555 -1.3 -2.0 hypothetical protein compare
RR42_RS15445 -1.3 -4.4 7-cyano-7-deazaguanine synthase compare
RR42_RS21150 -1.3 -1.7 hypothetical protein compare
RR42_RS27120 -1.3 -1.4 amino acid ABC transporter permease compare
RR42_RS25645 -1.3 -1.7 hypothetical protein compare
RR42_RS19010 -1.3 -4.7 shikimate kinase compare
RR42_RS32975 -1.3 -1.7 LysR family transcriptional regulator compare
RR42_RS29315 -1.3 -4.6 AcrR family transcriptional regulator compare
RR42_RS02430 -1.3 -6.1 sodium:solute symporter compare
RR42_RS17735 -1.3 -2.3 hypothetical protein compare
RR42_RS07615 -1.3 -1.7 3-ketoacyl-ACP reductase compare
RR42_RS11370 -1.3 -6.0 ABC transporter ATP-binding protein compare
RR42_RS31615 -1.3 -3.6 phosphate ABC transporter ATP-binding protein compare
RR42_RS14360 -1.2 -1.4 tryptophan synthase subunit alpha compare
RR42_RS05115 -1.2 -2.1 LysR family transcriptional regulator compare
RR42_RS09580 -1.2 -1.0 hypothetical protein compare
RR42_RS34715 -1.2 -3.1 hypothetical protein compare
RR42_RS31495 -1.2 -0.9 Cro/Cl family transcriptional regulator compare
RR42_RS36495 -1.2 -2.7 enoyl-CoA hydratase compare
RR42_RS03530 -1.2 -1.1 hypothetical protein compare
RR42_RS15785 -1.2 -3.5 glycosyl transferase family 28 compare
RR42_RS14625 -1.2 -2.8 formimidoylglutamase compare
RR42_RS06875 -1.2 -0.9 hypothetical protein compare
RR42_RS07455 -1.2 -5.7 ABC transporter substrate-binding protein compare
RR42_RS15410 -1.2 -3.5 membrane protein compare
RR42_RS16360 -1.2 -1.3 transposase compare
RR42_RS05500 -1.2 -1.0 preprotein translocase subunit SecG compare
RR42_RS15695 -1.1 -2.7 glycosyl transferase compare
RR42_RS01095 -1.1 -1.3 membrane protein compare
RR42_RS07570 -1.1 -4.1 hypothetical protein compare
RR42_RS05430 -1.1 -1.8 DNA-directed RNA polymerase sigma-70 factor compare
RR42_RS26235 -1.1 -3.4 GntR family transcriptional regulator compare
RR42_RS37110 -1.1 -2.0 hypothetical protein compare
RR42_RS06245 -1.1 -1.9 SAM-dependent methyltransferase compare
RR42_RS04475 -1.1 -5.5 3-phosphoshikimate 1-carboxyvinyltransferase compare
RR42_RS31960 -1.1 -1.2 biphenyl 2,3-dioxygenase compare
RR42_RS17400 -1.1 -3.2 queuine tRNA-ribosyltransferase compare
RR42_RS37320 -1.1 -1.9 hypothetical protein compare
RR42_RS14755 -1.1 -2.4 hypothetical protein compare
RR42_RS12055 -1.1 -3.1 acyltransferase compare
RR42_RS22180 -1.1 -2.1 hypothetical protein compare
RR42_RS19655 -1.1 -1.2 tRNA-Ala compare
RR42_RS18365 -1.1 -1.4 GTP-binding protein compare


Specific Phenotypes

For 32 genes in this experiment

For stress Doxycycline hyclate in Cupriavidus basilensis FW507-4G11

For stress Doxycycline hyclate across organisms