Experiment set14S724 for Methanococcus maripaludis S2

Compare to:

McCas_formate_complete Rifampicin 0.5 mM

200 most detrimental genes:

  gene name fitness t score description  
MMP_RS06165 +4.1 24.9 ABC transporter permease compare
MMP_RS01370 +3.7 15.3 acetate--CoA ligase family protein compare
MMP_RS06170 +3.7 16.0 ABC transporter ATP-binding protein compare
MMP_RS08370 +2.8 1.8 cation:proton antiporter subunit C compare
MMP_RS02605 +2.4 2.3 MotA/TolQ/ExbB proton channel family protein compare
MMP_RS08360 +2.1 8.9 hypothetical protein compare
MMP_RS06540 +2.1 5.2 3-methyl-2-oxobutanoate dehydrogenase subunit VorB compare
MMP_RS02790 +2.0 2.4 class III signal peptide-containing protein compare
MMP_RS06715 +1.9 12.4 cache domain-containing protein compare
MMP_RS08275 +1.9 8.6 hypothetical protein compare
MMP_RS06720 +1.8 5.7 response regulator transcription factor compare
MMP_RS02780 +1.8 8.5 hypothetical protein compare
MMP_RS04605 +1.8 5.2 cobalt ECF transporter T component CbiQ compare
MMP_RS08340 +1.8 4.5 4Fe-4S binding protein compare
MMP_RS07860 +1.7 1.0 hypothetical protein compare
MMP_RS08215 +1.6 2.9 DUF483 domain-containing protein compare
MMP_RS07725 +1.6 4.1 4Fe-4S dicluster domain-containing protein compare
MMP_RS07415 +1.6 3.8 molybdopterin-guanine dinucleotide biosynthesis protein MobB compare
MMP_RS08320 +1.6 7.2 molybdopterin molybdotransferase MoeA compare
MMP_RS06705 +1.6 3.2 formate/nitrite transporter family protein compare
MMP_RS04695 +1.5 5.0 selenide water dikinase SelD compare
MMP_RS06515 +1.5 3.1 UPF0489 family protein compare
MMP_RS00740 +1.4 2.7 cyclase family protein compare
MMP_RS02885 +1.4 10.6 molybdopterin biosynthesis protein compare
MMP_RS06545 +1.4 3.0 ferredoxin family protein compare
MMP_RS05825 +1.4 2.3 peptidyl-prolyl cis-trans isomerase compare
MMP_RS07705 +1.4 4.2 transcriptional regulator compare
MMP_RS06310 +1.3 2.4 NAD(P)/FAD-dependent oxidoreductase compare
MMP_RS08335 +1.3 2.6 NADH-quinone oxidoreductase subunit B family protein compare
MMP_RS08235 +1.3 4.8 hypothetical protein compare
MMP_RS05435 +1.3 4.5 5'/3'-nucleotidase SurE compare
MMP_RS06555 +1.2 3.1 cupin domain-containing protein compare
MMP_RS00345 +1.2 3.9 DUF2666 domain-containing protein compare
MMP_RS06990 +1.2 2.9 CatB-related O-acetyltransferase compare
MMP_RS08380 +1.2 4.6 phosphatase PAP2 family protein compare
MMP_RS08315 +1.2 1.6 S-methyl-5-thioribose-1-phosphate isomerase compare
MMP_RS05675 +1.2 2.3 phosphate ABC transporter ATP-binding protein PstB compare
MMP_RS06745 +1.2 2.0 DUF2119 domain-containing protein compare
MMP_RS01545 +1.2 1.0 CBS domain-containing protein compare
MMP_RS02045 +1.2 1.6 tRNA-Met compare
MMP_RS03320 +1.2 1.2 metal-dependent transcriptional regulator compare
MMP_RS06385 +1.1 3.1 hypothetical protein compare
MMP_RS08365 +1.1 2.5 energy conserving hydrogenase EhbF compare
MMP_RS04620 +1.1 3.6 cobalt transporter CbiM compare
MMP_RS07910 +1.1 4.3 NAD(P)H-hydrate dehydratase compare
MMP_RS01420 +1.1 1.6 hypothetical protein compare
MMP_RS07770 +1.1 2.9 alanine racemase compare
MMP_RS00670 +1.1 1.8 TIM barrel protein compare
MMP_RS07960 +1.1 5.6 sugar phosphate isomerase/epimerase compare
MMP_RS08345 +1.0 4.4 4Fe-4S binding protein compare
MMP_RS06325 +1.0 1.1 hypothetical protein compare
MMP_RS06550 +0.9 4.4 AMP-binding protein compare
MMP_RS01210 +0.9 3.2 sodium:solute symporter compare
MMP_RS01320 +0.9 3.3 hypothetical protein compare
MMP_RS07085 +0.9 3.4 ribonuclease HII compare
MMP_RS04145 +0.9 1.3 hypothetical protein compare
MMP_RS08670 +0.9 2.6 metallophosphoesterase compare
MMP_RS06860 +0.9 1.2 4Fe-4S binding protein compare
MMP_RS05460 +0.9 3.9 YcaO-related McrA-glycine thioamidation protein compare
MMP_RS03220 +0.9 1.3 RNA 2' 3'-cyclic phosphodiesterase compare
MMP_RS07335 +0.9 2.4 tRNA (cytidine(56)-2'-O)-methyltransferase compare
MMP_RS07835 +0.9 2.6 TldD/PmbA family protein compare
MMP_RS00125 +0.9 0.9 DUF2798 domain-containing protein compare
MMP_RS07905 +0.9 1.6 DUF3343 domain-containing protein compare
MMP_RS02300 +0.8 2.6 NAD(P)H-dependent oxidoreductase compare
MMP_RS03430 +0.8 3.5 bile acid:sodium symporter family protein compare
MMP_RS06335 +0.8 1.4 HAD family hydrolase compare
MMP_RS01645 +0.8 2.2 SWIM zinc finger family protein compare
MMP_RS03270 +0.8 2.8 ADP-ribosylglycohydrolase family protein compare
MMP_RS08555 +0.8 2.4 hypothetical protein compare
MMP_RS04615 +0.8 1.6 PDGLE domain-containing protein compare
MMP_RS03675 +0.8 4.3 RimK family alpha-L-glutamate ligase compare
MMP_RS06735 +0.8 2.8 class I SAM-dependent rRNA methyltransferase compare
MMP_RS05715 +0.8 2.3 hypothetical protein compare
MMP_RS06480 +0.8 2.0 ABC transporter substrate-binding protein compare
MMP_RS00990 +0.8 2.4 hypothetical protein compare
MMP_RS05065 +0.8 1.3 CooT family nickel-binding protein compare
MMP_RS05315 +0.8 0.7 hypothetical protein compare
MMP_RS03250 +0.8 1.0 MJ1244 family protein compare
MMP_RS02880 +0.8 2.2 AmmeMemoRadiSam system radical SAM enzyme compare
MMP_RS05780 +0.8 3.1 multidrug resistance efflux transporter family protein compare
MMP_RS01430 +0.7 2.1 mechanosensitive ion channel family protein compare
MMP_RS06075 +0.7 2.2 class I SAM-dependent methyltransferase compare
MMP_RS08750 +0.7 1.1 hypothetical protein compare
MMP_RS08075 +0.7 2.7 DUF749 domain-containing protein compare
MMP_RS01805 +0.7 1.5 NUDIX hydrolase compare
MMP_RS06665 +0.7 2.4 glycogen/starch synthase compare
MMP_RS00705 +0.7 0.8 hypothetical protein compare
MMP_RS06495 +0.7 1.8 YkgJ family cysteine cluster protein compare
MMP_RS01200 +0.7 1.3 hypothetical protein compare
MMP_RS00905 +0.7 2.3 phenylacetate--CoA ligase compare
MMP_RS00975 +0.7 2.5 HD domain-containing protein compare
MMP_RS06660 +0.7 2.3 glycosyltransferase family 4 protein compare
MMP_RS06225 +0.7 2.1 DNA double-strand break repair nuclease NurA compare
MMP_RS07970 +0.7 1.3 hypothetical protein compare
MMP_RS05895 +0.7 2.4 metallophosphoesterase compare
MMP_RS07125 +0.7 1.3 coenzyme F420-reducing hydrogenase FrhD protein compare
MMP_RS08090 +0.7 1.2 hypothetical protein compare
MMP_RS03685 +0.7 3.4 Mrp/NBP35 family ATP-binding protein compare
MMP_RS02015 +0.7 1.7 amidohydrolase compare
MMP_RS06710 +0.7 1.5 selenium-binding protein compare
MMP_RS07720 +0.6 3.5 4Fe-4S binding protein compare
MMP_RS05955 +0.6 0.8 CoB--CoM heterodisulfide reductase subunit C compare
MMP_RS05665 +0.6 2.0 phosphate ABC transporter permease subunit PstC compare
MMP_RS07715 +0.6 2.6 YfcE family phosphodiesterase compare
MMP_RS08845 +0.6 2.2 archaellum operon transcriptional activator EarA family protein compare
MMP_RS06100 +0.6 3.4 GNAT family N-acetyltransferase compare
MMP_RS06065 +0.6 3.9 iron ABC transporter substrate-binding protein compare
MMP_RS09025 +0.6 0.5 hypothetical protein compare
MMP_RS07925 +0.6 1.7 haloacid dehalogenase compare
MMP_RS03490 +0.6 0.8 DUF2115 domain-containing protein compare
MMP_RS06280 +0.6 2.1 alpha-glucan family phosphorylase compare
MMP_RS08490 +0.6 3.4 hypothetical protein compare
MMP_RS08245 +0.6 1.6 DUF4013 domain-containing protein compare
MMP_RS01540 +0.6 0.9 DUF504 domain-containing protein compare
MMP_RS07150 +0.6 1.5 MTH895/ArsE family thioredoxin-like protein compare
MMP_RS08690 +0.6 2.6 RNA-guided pseudouridylation complex pseudouridine synthase subunit Cbf5 compare
MMP_RS08390 +0.6 2.1 DUF5400 domain-containing protein compare
MMP_RS01675 +0.6 0.7 hypothetical protein compare
MMP_RS09035 +0.6 1.1 hypothetical protein compare
MMP_RS05945 +0.6 1.0 CBS domain-containing protein compare
MMP_RS05950 +0.6 2.1 nickel-dependent hydrogenase large subunit compare
MMP_RS02735 +0.6 1.8 MBL fold metallo-hydrolase compare
MMP_RS08700 +0.6 1.6 hypothetical protein compare
MMP_RS08350 +0.6 0.4 hypothetical protein compare
MMP_RS08405 +0.6 1.9 MFS transporter compare
MMP_RS04945 +0.6 1.1 hypothetical protein compare
MMP_RS01660 +0.6 0.9 hypothetical protein compare
MMP_RS08480 +0.5 1.9 molybdate ABC transporter substrate-binding protein compare
MMP_RS06910 +0.5 2.1 RlmF-related methyltransferase compare
MMP_RS06185 +0.5 1.5 thermonuclease family protein compare
MMP_RS01850 +0.5 1.9 phosphate ABC transporter substrate-binding protein compare
MMP_RS03740 +0.5 1.1 indolepyruvate oxidoreductase subunit beta compare
MMP_RS05695 +0.5 1.9 phospholipase D-like domain-containing protein compare
MMP_RS02170 +0.5 1.5 CBS domain-containing protein compare
MMP_RS08325 +0.5 2.3 hypothetical protein compare
MMP_RS06585 +0.5 0.6 DMT family protein compare
MMP_RS03420 +0.5 0.8 acetolactate synthase small subunit compare
MMP_RS00770 +0.5 1.3 hypothetical protein compare
MMP_RS06520 +0.5 1.0 DUF1786 domain-containing protein compare
MMP_RS08080 +0.5 1.8 YchF/TatD family DNA exonuclease compare
MMP_RS00635 +0.5 1.3 energy-coupling factor transporter transmembrane protein EcfT compare
MMP_RS08685 +0.5 2.7 hypothetical protein compare
MMP_RS04035 +0.5 1.1 hypothetical protein compare
MMP_RS00960 +0.5 1.2 iron export ABC transporter permease subunit FetB compare
MMP_RS00655 +0.5 0.5 hypothetical protein compare
MMP_RS03150 +0.5 1.5 phosphoglycerate mutase compare
MMP_RS08310 +0.5 0.6 TMEM165/GDT1 family protein compare
MMP_RS08355 +0.5 1.1 Na(+)/H(+) antiporter subunit B compare
MMP_RS02835 +0.5 0.9 CGGC domain-containing protein compare
MMP_RS04995 +0.5 2.1 hypothetical protein compare
MMP_RS00700 +0.5 1.6 OB-fold nucleic acid binding domain-containing protein compare
MMP_RS01605 +0.5 1.5 hypothetical protein compare
MMP_RS07850 +0.5 0.9 prephenate dehydratase compare
MMP_RS08070 +0.5 1.3 DUF2096 domain-containing protein compare
MMP_RS07550 +0.5 1.5 L-serine ammonia-lyase iron-sulfur-dependent subunit alpha compare
MMP_RS00530 +0.5 1.3 tRNA pseudouridine(54/55) synthase Pus10 compare
MMP_RS00845 +0.5 2.2 acetate--CoA ligase compare
MMP_RS08400 +0.5 0.8 MJ0307 family thioredoxin compare
MMP_RS01765 +0.5 1.9 HIT family protein compare
MMP_RS05325 +0.5 1.7 hypothetical protein compare
MMP_RS04625 +0.5 2.2 DEAD/DEAH box helicase compare
MMP_RS04310 +0.5 1.2 hypothetical protein compare
MMP_RS07140 +0.5 2.4 TIGR00341 family protein compare
MMP_RS01640 +0.5 1.5 2-oxoacid:acceptor oxidoreductase subunit alpha compare
MMP_RS06575 +0.5 0.8 fluoride efflux transporter CrcB compare
MMP_RS08755 +0.5 1.7 sodium:solute symporter family protein compare
MMP_RS01855 +0.5 1.3 2-hydroxyacyl-CoA dehydratase family protein compare
MMP_RS01870 +0.4 1.8 acyl-CoA dehydratase activase compare
MMP_RS02805 +0.4 0.4 HEPN domain-containing protein compare
MMP_RS03980 +0.4 1.8 hypothetical protein compare
MMP_RS05595 +0.4 2.2 imidazole glycerol phosphate synthase subunit HisH compare
MMP_RS04815 +0.4 1.3 chemotaxis protein CheD compare
MMP_RS08665 +0.4 2.4 hypothetical protein compare
MMP_RS08850 +0.4 2.6 hypothetical protein compare
MMP_RS03215 +0.4 1.9 MBL fold metallo-hydrolase compare
MMP_RS06965 +0.4 1.3 TIGR04014 family B12-binding domain/radical SAM domain-containing protein compare
MMP_RS05485 +0.4 2.1 cysteine--tRNA ligase compare
MMP_RS00100 +0.4 2.2 tRNA pseudouridine(13) synthase TruD compare
MMP_RS07955 +0.4 1.0 FumA C-terminus/TtdB family hydratase beta subunit compare
MMP_RS06560 +0.4 1.9 hypothetical protein compare
MMP_RS02645 +0.4 1.6 ArsR family transcriptional regulator compare
MMP_RS00760 +0.4 1.3 branched-chain-amino-acid transaminase compare
MMP_RS06535 +0.4 0.8 2-oxoacid:acceptor oxidoreductase family protein compare
MMP_RS05900 +0.4 1.9 tetratricopeptide repeat protein compare
MMP_RS06060 +0.4 1.5 hypothetical protein compare
MMP_RS07855 +0.4 1.7 class I SAM-dependent methyltransferase compare
MMP_RS08775 +0.4 1.4 methanogenesis marker 9 domain-containing protein compare
MMP_RS00090 +0.4 1.2 CoA-binding protein compare
MMP_RS01680 +0.4 1.8 phenylacetate--CoA ligase compare
MMP_RS03750 +0.4 1.2 ACT domain-containing protein compare
MMP_RS06655 +0.4 1.9 glycoside hydrolase family 15 protein compare
MMP_RS00120 +0.4 1.0 LysR family transcriptional regulator compare
MMP_RS03275 +0.4 1.4 TIGR00266 family protein compare
MMP_RS00285 +0.4 1.3 TIGR04013 family B12-binding domain/radical SAM domain-containing protein compare
MMP_RS07560 +0.4 0.9 prefoldin subunit alpha compare
MMP_RS05820 +0.4 1.0 RNA-binding transcriptional accessory protein compare
MMP_RS08415 +0.4 0.4 radical SAM protein compare
MMP_RS04840 +0.4 1.8 response regulator compare
MMP_RS02595 +0.4 0.4 putative zinc-binding protein compare


Specific Phenotypes

For 2 genes in this experiment

For stress Rifampicin in Methanococcus maripaludis S2

For stress Rifampicin across organisms