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Experiment set13IT093 for
Sinorhizobium meliloti 1021
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Parafilmed volatile agar plate with no fungus
200 most detrimental genes:
gene
name
fitness
t score
description
SMc04001
+2.8
3.4
phosphoribosylaminoimidazole carboxylase catalytic subunit protein
compare
SMc00150
+2.7
23.4
hypothetical protein
compare
SMc01595
+2.6
7.7
sensor histidine kinase transmembrane protein
compare
SMc01907
+2.4
17.7
hypothetical protein
compare
SMc02719
+2.3
1.3
transposase
compare
SMc01099
+2.3
4.0
tRNA pseudouridine synthase A
compare
SMc03900
+2.2
15.3
cyclic beta-1,2-glucan ABc transporter
compare
SMc04094
+2.1
5.0
hypothetical protein
compare
SMc04382
+2.1
18.6
beta-(1,2)-glucan production associated transmembrane protein
compare
SMc01222
+2.1
8.0
lipopolysaccharide core biosynthesis glycosyl transferase
compare
SMc00247
+1.9
9.6
phosphatidylcholine synthase
compare
SMc02367
+1.9
8.4
sensor histidine kinase transmembrane protein
compare
SMc00838
+1.8
5.1
hypothetical protein
compare
SMc00131
+1.8
11.8
transcriptional regulator
compare
SMc02497
+1.8
2.8
hypothetical protein
compare
SM
_b20613
+1.7
7.8
C4-dicarboxylate transport transcriptional regulator
compare
SMa0753
+1.7
0.9
hypothetical protein
compare
SMc01120
+1.7
4.9
hypothetical protein
compare
SMc02084
+1.7
1.3
biopolymer transport transmembrane protein
compare
SM
_b20043
+1.6
7.0
hypothetical protein
compare
SMc03123
+1.6
11.9
transcriptional regulator
compare
SMc00761
+1.6
10.3
oxidoreductase
compare
SMc00337
+1.5
1.5
hypothetical protein
compare
SMc02485
+1.5
2.1
signal peptide protein
compare
SMc02366
+1.5
8.8
transcriptional regulator
compare
SMc00129
+1.4
6.3
sensor histidine kinase
compare
SM
_b20293
+1.4
1.5
hypothetical protein
compare
SMc04220
+1.4
1.5
transcriptional regulator
compare
SMc00458
+1.4
10.4
transcriptional regulator
compare
SM
_b20387
+1.4
1.7
transcriptional regulator
compare
SM
_b21374
+1.4
2.0
tagatose kinase (EC 2.7.1.101)
(from data)
compare
SMc00352
+1.4
2.5
acetyltransferase
compare
SMc01223
+1.4
3.1
transcriptional regulator
compare
SMa5010
+1.4
1.3
hypothetical protein
compare
SMc00619
+1.4
0.9
hypothetical protein
compare
SMc00239
+1.3
0.9
hypothetical protein
compare
SMc01991
+1.3
1.7
short chain dehydrogenase
compare
SMc01858
+1.3
1.3
S-adenosyl-methyltransferase MraW
compare
SMc02449
+1.3
3.3
acetyltransferase
compare
SMc00431
+1.3
4.0
hypothetical protein
compare
SM
_b21491
+1.3
8.5
hypothetical protein
compare
SM
_b20935
+1.2
3.2
transcriptional regulator
compare
SMc02269
+1.2
6.2
capsular polysaccharide biosynthesis/export protein
compare
SMc02273
+1.2
10.6
fatty acid synthase transmembrane protein
compare
SMc01216
+1.2
0.9
hypothetical protein
compare
SMc03153
+1.2
3.4
keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase
compare
SMa1779
+1.2
2.1
hypothetical protein
compare
SMc02684
+1.2
6.4
hydrolase/peptidase
compare
SMc01769
+1.2
7.3
hypothetical protein
compare
SMa1570
+1.2
1.6
PilA2 pilus assembly protein
compare
SM
_b21192
+1.2
6.6
fructose-1,6-bisphosphate aldolase
compare
SMa1658
+1.2
2.1
hypothetical protein
compare
SMc01364
+1.2
1.2
DNA topoisomerase I
compare
SM
_b21170
+1.2
3.1
guanylate kinase
compare
SMa0748
+1.2
1.9
MucR family transcriptional regulator
compare
SMc00540
+1.1
2.2
hypothetical protein
compare
SM
_b21266
+1.1
4.6
hypothetical protein
compare
SMc04000
+1.1
4.3
hypothetical protein
compare
SMc03836
+1.1
1.4
acyl-CoA thioesterase i protein
compare
SMc00522
+1.1
7.5
ATP-dependent RNA helicase
compare
SMc00403
+1.1
4.3
NOL1/NOP2/SUN family signature protein
compare
SMc03855
+1.1
2.6
hypothetical protein
compare
SMc04297
+1.1
2.2
transcriptional regulator
compare
SM
_b20746
+1.1
1.3
hypothetical protein
compare
SMc00075
+1.1
3.7
ribosomal-protein-alanine acetyltransferase
compare
SMa5036
+1.1
2.7
hypothetical protein
compare
SMc01613
+1.1
2.7
ribose-5-phosphate isomerase B
compare
SMc00495
+1.1
5.0
phosphoribosylaminoimidazolesuccinocarboxamide synthase
compare
SMc03963
+1.1
4.7
sulfolipid biosynthesis protein
compare
SMc00505
+1.1
1.8
hypothetical protein
compare
SMc03002
+1.1
2.7
hypothetical protein
compare
SMc04081
+1.1
6.1
glycosyl transferase (sulfolipid biosynthesis) protein
compare
SM
_b20960
+1.1
5.2
UDP-glucose pyrophosphorylase
compare
SMc00061
+1.0
2.8
hypothetical protein
compare
SMc00618
+1.0
7.3
polyphosphate kinase
compare
SMc01615
+1.0
3.0
transcriptional regulator
compare
SMc04211
+1.0
2.4
hypothetical protein
compare
SMc00361
+1.0
1.5
hypothetical protein
compare
SMc00494
+1.0
1.4
phosphoribosylformylglycinamidine synthase subunit PurS
compare
SMc02490
+1.0
5.1
hypothetical protein
compare
SMc02137
+1.0
2.0
ornithine carbamoyltransferase
compare
SMc02272
+1.0
4.8
acyl-transferase transferase
compare
SMc01131
+1.0
3.1
hypothetical protein
compare
SMc03111
+1.0
4.6
mannose 6-phosphate isomerase (EC 5.3.1.8)
(from data)
compare
SMc00349
+1.0
4.0
GTP-binding protein LepA
compare
SMc02041
+1.0
1.4
short chain dehydrogenase
compare
SM
_b21256
+1.0
5.6
nucleotide sugar oxidase
compare
SMc03842
+1.0
1.6
hypothetical protein
compare
SMc00455
+1.0
3.0
hypothetical protein
compare
SM
_b21397
+0.9
1.1
hypothetical protein
compare
SMc02434
+0.9
1.3
hypothetical protein
compare
SMa1702
+0.9
2.3
hypothetical protein
compare
SM
_b21252
+0.9
5.8
glycosyltransferase
compare
SMc02854
+0.9
5.0
signal peptide protein
compare
SMa0166
+0.9
2.3
hypothetical protein
compare
SMc02478
+0.9
5.1
hypothetical protein
compare
SMa2289
+0.9
0.8
hypothetical protein
compare
SMc01984
+0.9
1.1
cytochrome-C oxidase transmembrane protein
compare
SMa1894
+0.9
1.7
methionine sulfoxide reductase B
compare
SMc01351
+0.9
1.9
hypothetical protein
compare
SMc03072
+0.9
1.6
hypothetical protein
compare
SMc02799
+0.9
1.6
16S rRNA methyltransferase GidB
compare
SMc00973
+0.9
1.7
hypothetical protein
compare
SM
_b21372
+0.9
5.7
LacI family transcriptional regulator
compare
SMa0834
+0.9
3.9
FdxB ferredoxin III
compare
SMa0210
+0.9
2.2
hypothetical protein
compare
SMc03250
+0.9
2.1
hypothetical protein
compare
SMc04174
+0.9
0.7
signal peptide protein
compare
SM
_b20866
+0.9
2.6
hypothetical protein
compare
SMa0091
+0.9
2.1
hypothetical protein
compare
SMa0312
+0.9
1.6
hypothetical protein
compare
SMa1118
+0.9
1.1
HspC2 heat shock protein
compare
SMa0854
+0.9
1.9
3-ketoacyl-ACP reductase
compare
SMc00565
+0.9
1.1
50S ribosomal protein L9
compare
SM
_b21689
+0.9
1.7
hypothetical protein
compare
SMc00396
+0.9
1.8
hypothetical protein
compare
SMc00390
+0.9
1.5
hypothetical protein
compare
SMa1400
+0.8
1.7
acyl-CoA dehydrogenase
compare
SMa5033
+0.8
0.6
hypothetical protein
compare
SMc02173
+0.8
1.2
hypothetical protein
compare
SMc00286
+0.8
0.7
hemolysin-type calcium-binding protein
compare
SMc01107
+0.8
4.1
hypothetical protein
compare
SMa1547
+0.8
1.7
protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)
compare
SMc02697
+0.8
0.8
hypothetical protein
compare
SM
_b20577
+0.8
2.6
protocatechuate 3,4-dioxygenase subunit beta
compare
SMc04462
+0.8
1.9
glycerate dehydrogenase
compare
SM
_b20537
+0.8
3.4
transcriptional regulator
compare
SMc03961
+0.8
3.6
sulfolipid (UDP-sulfoquinovose) biosynthesis protein
compare
SM
_b20955
+0.8
1.7
endo-beta-1,3-1,4-glycanase
compare
SMc04213
+0.8
1.2
diacylglycerol kinase
compare
SM
_b21678
+0.8
1.1
hypothetical protein
compare
SM
_b20392
+0.8
3.3
transcriptional regulator NanR
compare
SMc02615
+0.8
1.5
signal peptide protein
compare
SMc00166
+0.8
0.9
oxidoreductase NAD protein
compare
SM
_b20347
+0.8
2.3
transcriptional regulator
compare
SMc02271
+0.8
3.8
ribitol type dehydrogenase
compare
SMa1100
+0.8
2.2
hypothetical protein
compare
SMa1002
+0.8
0.9
hypothetical protein
compare
SMc03179
+0.8
4.2
monovalent cation/H+ antiporter subunit A
compare
SMc02778
+0.8
0.8
hydroxyacid aldolase
compare
SMc00288
+0.8
2.4
signal peptide protein
compare
SMc00325
+0.8
3.7
hypothetical protein
compare
SMc01455
+0.8
2.3
D-lactate dehydrogenase (cytochrome) protein
compare
SMc04381
+0.8
3.4
hypothetical protein
compare
SMc03156
+0.8
3.0
hypothetical protein
compare
SMc02655
+0.8
1.8
hypothetical protein
compare
SM
_b20959
+0.8
4.3
glucosyltransferase
compare
SM
_b20750
+0.8
0.9
dehydrogenase
compare
SMc03831
+0.8
2.7
hypothetical protein
compare
SMa0126
+0.8
1.0
CspA8 Cold shock family protein
compare
SM
_b20326
+0.8
2.4
ABC transporter for D-trehalose/D-maltose/sucrose, permease component 1 (ThuF)
(from data)
compare
SMc00241
+0.8
1.4
transcriptional regulator
compare
SMc01454
+0.8
4.0
hypothetical protein
compare
SMc01806
+0.8
2.0
enoyl-CoA hydratase
compare
SMc00090
+0.8
3.4
sulfate adenylyltransferase
compare
SMc00976
+0.8
1.2
enoyl-CoA hydratase
compare
SMc02614
+0.8
1.7
hypothetical protein
compare
SMc04043
+0.8
3.6
hypothetical protein
compare
SMc03932
+0.8
1.5
sarcosine oxidase subunit delta
compare
SMc02384
+0.8
2.4
glycosyltransferase transmembrane protein
compare
SM
_b21471
+0.8
1.9
hypothetical protein
compare
SMc02520
+0.8
3.7
glycerol-3-phosphate dehydrogenase (EC 1.1.5.3)
(from data)
compare
SMc04327
+0.8
0.7
hypothetical protein
compare
SMc00425
+0.8
1.1
transcriptional regulator
compare
SM
_b21269
+0.8
4.6
ABC transporter ATPase
compare
SM
_b20684
+0.8
5.8
hypothetical protein
compare
SMc00060
+0.8
2.8
hypothetical protein
compare
SM
_b20571
+0.8
2.8
aliphatic sulfonate ABC transporter permease
compare
SM
_b20210
+0.8
1.0
oxidoreductase
compare
SM
_b21265
+0.8
4.7
glycosyltransferase
compare
SM
_b20261
+0.8
1.6
malate dehydrogenase
compare
SMc00812
+0.8
1.8
hypothetical protein
compare
SM
_b20320
+0.8
0.7
TRAP-type large permease component
compare
SMc00482
+0.8
3.9
hypothetical protein
compare
SM
_b21225
+0.7
1.3
inositol monophosphatase
compare
SM
_b20117
+0.7
1.1
sugar transferase
compare
SM
_b20131
+0.7
1.2
oxidoreductase
compare
SMc01698
+0.7
2.8
oxidoreductase
compare
SMc01177
+0.7
1.9
hypothetical protein
compare
SMa5007
+0.7
2.4
transcriptional regulator
compare
SM
_b21026
+0.7
2.3
exopeptide
compare
SMc02765
+0.7
4.1
tryptophan synthase subunit alpha
compare
SMc00044
+0.7
2.2
amino acid efflux protein
compare
SM
_b21304
+0.7
2.6
NG,NG-dimethylarginine dimethylaminohydrolase (dimethylargininase) protein
compare
SM
_b20921
+0.7
1.2
hypothetical protein
compare
SMc00799
+0.7
2.3
hypothetical protein
compare
SMa1210
+0.7
2.6
nitrogen fixation protein FixH
compare
SM
_b20050
+0.7
1.2
hypothetical protein
compare
SMc00727
+0.7
3.4
3-hydroxybutyryl-CoA dehydrogenase
compare
SMc02112
+0.7
3.4
hypothetical protein
compare
SMc03182
+0.7
2.4
pH adaptation potassium efflux system E transmembrane protein
compare
SMc04232
+0.7
1.0
glycine rich transmembrane protein
compare
SMc00414
+0.7
5.2
hypothetical protein
compare
SM
_b20834
+0.7
4.2
surface saccharide synthesis protein
compare
SMc04404
+0.7
0.8
amino acid efflux transmembrane protein
compare
SMc01139
+0.7
1.9
RNA polymerase factor sigma-54
compare
SMc01232
+0.7
1.6
hypothetical protein
compare
SMc02270
+0.7
4.9
capsular polysaccharide biosynthesis\export transmembrane protein
compare
SMc03972
+0.7
3.3
multidrug efflux system transmembrane protein
compare
SMc03787
+0.7
2.4
hypothetical protein
compare
Specific Phenotypes
For 3 genes in this experiment