Experiment set12IT032 for Klebsiella michiganensis M5al

Compare to:

RCH2_defined_glucose with 2,2'-Dipyridyl 100 uM

200 most important genes:

  gene name fitness t score description  
BWI76_RS09755 -6.0 -9.1 phosphoserine transaminase compare
BWI76_RS20355 -5.1 -5.1 colicin V production protein compare
BWI76_RS00400 -5.0 -3.4 glutamine synthetase compare
BWI76_RS04160 -4.9 -7.8 phosphoserine phosphatase compare
BWI76_RS10990 -4.8 -4.7 dihydroorotase compare
BWI76_RS01615 -4.7 -13.3 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/inosine monophosphate cyclohydrolase compare
BWI76_RS07070 -4.6 -5.2 5-(carboxyamino)imidazole ribonucleotide mutase compare
BWI76_RS04470 -4.5 -11.9 carbamoyl phosphate synthase large subunit compare
BWI76_RS23360 -4.5 -6.1 diaminopimelate decarboxylase compare
BWI76_RS04465 -4.5 -4.8 carbamoyl-phosphate synthase small subunit compare
BWI76_RS04645 -4.4 -6.4 3-dehydroquinase compare
BWI76_RS17720 -4.4 -1.9 muramoyltetrapeptide carboxypeptidase compare
BWI76_RS07065 -4.3 -6.6 5-(carboxyamino)imidazole ribonucleotide synthase compare
BWI76_RS23240 -4.3 -3.0 exonuclease V subunit gamma compare
BWI76_RS23920 -4.3 -8.2 D-3-phosphoglycerate dehydrogenase compare
BWI76_RS11965 -4.1 -6.9 orotidine-5'-phosphate decarboxylase compare
BWI76_RS20350 -4.1 -5.1 amidophosphoribosyltransferase compare
BWI76_RS21265 -4.1 -13.2 phosphoribosylformylglycinamidine synthase compare
BWI76_RS20965 -4.1 -5.6 phosphoribosylformylglycinamidine cyclo-ligase compare
BWI76_RS09910 -4.0 -17.1 dihydroorotate dehydrogenase (quinone) compare
BWI76_RS09760 -3.9 -4.9 3-phosphoshikimate 1-carboxyvinyltransferase compare
BWI76_RS18950 -3.9 -7.4 imidazole glycerol phosphate synthase cyclase subunit compare
BWI76_RS20895 -3.9 -6.0 phosphoribosylaminoimidazolesuccinocarboxamide synthase compare
BWI76_RS02995 -3.9 -6.1 aspartate carbamoyltransferase compare
BWI76_RS01610 -3.7 -8.0 phosphoribosylamine--glycine ligase compare
BWI76_RS20435 -3.7 -2.2 chorismate synthase compare
BWI76_RS05835 -3.6 -3.1 gamma-glutamyl-phosphate reductase compare
BWI76_RS23230 -3.5 -3.4 exodeoxyribonuclease V subunit beta compare
BWI76_RS18935 -3.5 -8.3 bifunctional imidazole glycerol-phosphate dehydratase/histidinol phosphatase compare
BWI76_RS08385 -3.5 -5.8 citrate (Si)-synthase compare
BWI76_RS27390 -3.5 -6.1 ribonuclease PH compare
BWI76_RS00990 -3.4 -8.6 ketol-acid reductoisomerase compare
BWI76_RS04255 -3.4 -12.8 threonine synthase compare
BWI76_RS27385 -3.2 -4.6 orotate phosphoribosyltransferase compare
BWI76_RS23265 -3.2 -5.0 hypothetical protein compare
BWI76_RS26085 -3.2 -2.0 3-dehydroquinate synthase compare
BWI76_RS00855 -3.2 -9.9 argininosuccinate lyase compare
BWI76_RS23365 -3.2 -6.4 LysR family transcriptional regulator compare
BWI76_RS00975 -3.1 -8.7 dihydroxy-acid dehydratase compare
BWI76_RS23220 -3.1 -8.5 amino-acid N-acetyltransferase compare
BWI76_RS25115 -3.1 -9.7 argininosuccinate synthase compare
BWI76_RS21475 -3.0 -6.5 bifunctional chorismate mutase/prephenate dehydrogenase compare
BWI76_RS09660 -3.0 -2.0 DNA translocase FtsK compare
BWI76_RS05840 -3.0 -5.9 glutamate 5-kinase compare
BWI76_RS04305 -3.0 -1.8 molecular chaperone DnaJ compare
BWI76_RS04250 -2.9 -7.5 homoserine kinase compare
BWI76_RS00850 -2.9 -9.1 acetylglutamate kinase compare
BWI76_RS18920 -2.9 -4.4 ATP phosphoribosyltransferase compare
BWI76_RS00835 -2.8 -13.5 phosphoenolpyruvate carboxylase compare
BWI76_RS22755 -2.8 -8.8 phosphoadenosine phosphosulfate reductase compare
BWI76_RS22765 -2.8 -14.4 sulfite reductase subunit alpha compare
BWI76_RS04245 -2.8 -14.6 bifunctional aspartate kinase/homoserine dehydrogenase I compare
BWI76_RS00845 -2.7 -7.3 N-acetyl-gamma-glutamyl-phosphate reductase compare
BWI76_RS18940 -2.7 -6.5 imidazole glycerol phosphate synthase subunit HisH compare
BWI76_RS00980 -2.7 -10.8 PLP-dependent threonine dehydratase compare
BWI76_RS03010 -2.7 -11.3 ornithine carbamoyltransferase compare
BWI76_RS08380 -2.6 -2.3 endonuclease VIII compare
BWI76_RS22760 -2.5 -7.0 sulfite reductase subunit beta compare
BWI76_RS26000 -2.5 -10.6 aspartate aminotransferase family protein compare
BWI76_RS01655 -2.5 -8.3 homoserine O-succinyltransferase compare
BWI76_RS18955 -2.4 -7.8 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase compare
BWI76_RS25645 -2.4 -9.3 shikimate dehydrogenase compare
BWI76_RS27430 -2.4 -2.3 (p)ppGpp synthetase compare
BWI76_RS01210 -2.4 -1.5 tyrosine recombinase XerC compare
BWI76_RS20650 -2.4 -3.2 phosphoenolpyruvate--protein phosphotransferase compare
BWI76_RS00785 -2.4 -7.4 cystathionine gamma-synthase compare
BWI76_RS19870 -2.3 -3.1 malate:quinone oxidoreductase compare
BWI76_RS20970 -2.3 -2.6 phosphoribosylglycinamide formyltransferase compare
BWI76_RS22690 -2.3 -3.9 adenylyl-sulfate kinase compare
BWI76_RS00805 -2.3 -5.8 5,10-methylenetetrahydrofolate reductase compare
BWI76_RS24285 -2.3 -6.9 cystathionine beta-lyase compare
BWI76_RS04665 -2.2 -16.2 3-isopropylmalate dehydratase small subunit compare
BWI76_RS18930 -2.2 -7.7 histidinol-phosphate transaminase compare
BWI76_RS18925 -2.2 -4.3 histidinol dehydrogenase compare
BWI76_RS00180 -2.2 -2.5 F0F1 ATP synthase subunit epsilon compare
BWI76_RS02735 -2.2 -4.6 3'(2'),5'-bisphosphate nucleotidase CysQ compare
BWI76_RS21465 -2.1 -6.3 bifunctional chorismate mutase/prephenate dehydratase compare
BWI76_RS04670 -2.1 -7.4 3-isopropylmalate dehydratase large subunit compare
BWI76_RS04715 -2.1 -2.6 division/cell wall cluster transcriptional repressor MraZ compare
BWI76_RS04510 -2.1 -2.9 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) compare
BWI76_RS04240 -2.1 -3.8 thr operon leader peptide compare
BWI76_RS04680 -2.1 -11.9 2-isopropylmalate synthase compare
BWI76_RS22805 -2.0 -9.4 GTP diphosphokinase compare
BWI76_RS04685 -2.0 -8.7 putative leucine operon leader peptide compare
BWI76_RS02530 -2.0 -2.8 tRNA dimethylallyltransferase compare
BWI76_RS20900 -2.0 -1.7 outer membrane protein assembly factor BamC compare
BWI76_RS05015 -2.0 -4.1 transcriptional regulator compare
BWI76_RS01200 -2.0 -1.8 diaminopimelate epimerase compare
BWI76_RS17980 -1.9 -5.8 RNA chaperone ProQ compare
BWI76_RS12090 -1.9 -2.9 HNH endonuclease compare
BWI76_RS17975 -1.9 -5.2 tail-specific protease compare
BWI76_RS05200 -1.8 -3.7 bifunctional uridylyltransferase/uridylyl-removing protein compare
BWI76_RS09655 -1.8 -5.0 leucine-responsive regulatory protein compare
BWI76_RS15215 -1.7 -1.6 N-acetyltransferase compare
BWI76_RS26395 -1.7 -2.8 cell division protein FtsE compare
BWI76_RS20640 -1.7 -6.0 cysteine synthase A compare
BWI76_RS25320 -1.6 -8.1 glutamate synthase compare
BWI76_RS04675 -1.6 -5.6 3-isopropylmalate dehydrogenase compare
BWI76_RS25315 -1.6 -9.3 glutamate synthase large subunit compare
BWI76_RS26460 -1.6 -3.0 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE compare
BWI76_RS18065 -1.6 -2.6 DNA polymerase III subunit theta compare
BWI76_RS20380 -1.6 -1.8 tRNA pseudouridine(38-40) synthase TruA compare
BWI76_RS11850 -1.6 -7.6 bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase compare
BWI76_RS11845 -1.6 -4.9 tryptophan synthase subunit beta compare
BWI76_RS08525 -1.6 -2.9 colicin transporter compare
BWI76_RS26570 -1.6 -3.2 anion permease compare
BWI76_RS26390 -1.5 -2.6 cell division protein FtsX compare
BWI76_RS00390 -1.5 -3.8 two-component system sensor histidine kinase NtrB compare
BWI76_RS01800 -1.5 -4.1 glucose-6-phosphate isomerase compare
BWI76_RS11860 -1.5 -6.3 anthranilate synthase component I compare
BWI76_RS16485 -1.5 -1.9 ribonuclease T compare
BWI76_RS11235 -1.5 -1.6 hypothetical protein compare
BWI76_RS09645 -1.4 -1.3 thioredoxin-disulfide reductase compare
BWI76_RS11840 -1.4 -2.5 tryptophan synthase subunit alpha compare
BWI76_RS00385 -1.4 -6.2 nitrogen assimilation regulatory protein compare
BWI76_RS26470 -1.4 -5.8 4-deoxy-4-formamido-L-arabinose- phosphoundecaprenol deformylase compare
BWI76_RS00965 -1.4 -1.4 acetolactate synthase 2 small subunit compare
BWI76_RS26055 -1.4 -6.1 siroheme synthase compare
BWI76_RS00760 -1.3 -3.9 cell division protein FtsN compare
BWI76_RS08535 -1.3 -1.7 translocation protein TolB compare
BWI76_RS06905 -1.3 -6.8 Cu+ exporting ATPase compare
BWI76_RS14410 -1.2 -3.3 hypothetical protein compare
BWI76_RS11855 -1.2 -4.3 bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase compare
BWI76_RS21480 -1.2 -4.9 phospho-2-dehydro-3-deoxyheptonate aldolase compare
BWI76_RS08530 -1.2 -2.4 protein TolA compare
BWI76_RS00985 -1.2 -5.0 transcriptional regulator IlvY compare
BWI76_RS25335 -1.2 -2.9 stringent starvation protein A compare
BWI76_RS21345 -1.2 -2.2 sigma-E factor regulatory protein RseB compare
BWI76_RS20995 -1.2 -3.4 RNA degradosome polyphosphate kinase compare
BWI76_RS07730 -1.2 -1.7 iron-enterobactin transporter membrane protein compare
BWI76_RS25600 -1.2 -1.3 tRNA-Thr compare
BWI76_RS19845 -1.1 -4.4 phosphatase compare
BWI76_RS02580 -1.1 -1.8 23S rRNA (guanosine(2251)-2'-O)-methyltransferase compare
BWI76_RS23885 -1.1 -2.0 2-octaprenylphenol hydroxylase compare
BWI76_RS16965 -1.1 -2.2 murein lipoprotein compare
BWI76_RS26455 -1.1 -2.6 4-amino-4-deoxy-L-arabinose-phospho-UDP flippase compare
BWI76_RS27425 -1.1 -2.0 DNA-directed RNA polymerase subunit omega compare
BWI76_RS24900 -1.1 -1.6 DeoR family transcriptional regulator compare
BWI76_RS00355 -1.1 -2.1 DNA polymerase I compare
BWI76_RS21370 -1.1 -1.6 ATP-dependent RNA helicase SrmB compare
BWI76_RS04270 -1.1 -3.3 transaldolase compare
BWI76_RS07465 -1.1 -2.5 TetR family transcriptional regulator compare
BWI76_RS20440 -1.1 -1.0 50S ribosomal protein L3 N(5)-glutamine methyltransferase compare
BWI76_RS15680 -1.0 -2.7 hypothetical protein compare
BWI76_RS27440 -1.0 -3.4 DNA helicase RecG compare
BWI76_RS09255 -1.0 -2.2 hypothetical protein compare
BWI76_RS13645 -1.0 -2.0 N-hydroxyarylamine O-acetyltransferase compare
BWI76_RS23480 -1.0 -5.6 EAL domain-containing protein compare
BWI76_RS13785 -1.0 -1.6 ABC transporter permease compare
BWI76_RS07740 -1.0 -1.9 Fe2+-enterobactin ABC transporter substrate-binding protein compare
BWI76_RS27235 -1.0 -6.0 murein hydrolase activator EnvC compare
BWI76_RS15290 -1.0 -1.4 transcriptional regulator compare
BWI76_RS14390 -1.0 -1.9 hypothetical protein compare
BWI76_RS07645 -0.9 -1.6 short-chain dehydrogenase/reductase compare
BWI76_RS06765 -0.9 -1.9 transcriptional regulator compare
BWI76_RS08665 -0.9 -4.8 6-phosphogluconolactonase compare
BWI76_RS26200 -0.9 -3.6 starch synthase compare
BWI76_RS18770 -0.9 -1.2 DNA gyrase inhibitor compare
BWI76_RS01350 -0.9 -1.0 NAD(P)H-flavin reductase compare
BWI76_RS09650 -0.9 -3.5 hypothetical protein compare
BWI76_RS21565 -0.9 -1.0 outer membrane protein assembly factor BamE compare
BWI76_RS00345 -0.9 -1.9 protein disulfide oxidoreductase DsbA compare
BWI76_RS13970 -0.9 -1.7 ABC transporter compare
BWI76_RS19685 -0.9 -4.3 lysine transporter compare
BWI76_RS19840 -0.8 -1.2 hypothetical protein compare
BWI76_RS22450 -0.8 -1.7 selenoprotein W-related protein compare
BWI76_RS09635 -0.8 -1.4 amino acid ABC transporter ATP-binding protein compare
BWI76_RS09870 -0.8 -3.9 aromatic amino acid aminotransferase compare
BWI76_RS00960 -0.8 -2.1 acetolactate synthase 2 catalytic subunit compare
BWI76_RS04955 -0.8 -1.7 hypoxanthine phosphoribosyltransferase compare
BWI76_RS15835 -0.8 -0.8 hypothetical protein compare
BWI76_RS11300 -0.8 -1.0 cupin compare
BWI76_RS01685 -0.8 -4.5 methionine synthase compare
BWI76_RS16000 -0.8 -1.1 multidrug transporter subunit MdtI compare
BWI76_RS01890 -0.7 -1.9 transcriptional regulator Zur compare
BWI76_RS05235 -0.7 -0.9 hypothetical protein compare
BWI76_RS22700 -0.7 -3.2 sulfate adenylyltransferase subunit 2 compare
BWI76_RS01135 -0.7 -3.0 lipopolysaccharide N-acetylmannosaminouronosyltransferase compare
BWI76_RS22300 -0.7 -1.6 hydrogenase 3 maturation endopeptidase HyCI compare
BWI76_RS20050 -0.7 -1.2 hypothetical protein compare
BWI76_RS01330 -0.7 -1.3 twin-arginine translocase subunit TatC compare
BWI76_RS27225 -0.7 -1.9 rhodanese-like domain-containing protein compare
BWI76_RS01790 -0.7 -5.6 lysine-sensitive aspartokinase 3 compare
BWI76_RS25505 -0.7 -3.8 RNase E specificity factor CsrD compare
BWI76_RS17180 -0.7 -1.5 hypothetical protein compare
BWI76_RS13045 -0.7 -3.0 hypothetical protein compare
BWI76_RS12460 -0.7 -2.0 envelope stress response membrane protein PspC compare
BWI76_RS01070 -0.7 -3.4 thiol reductase thioredoxin compare
BWI76_RS26075 -0.7 -2.4 DNA adenine methylase compare
BWI76_RS25070 -0.7 -1.1 hypothetical protein compare
BWI76_RS23485 -0.7 -3.0 hypothetical protein compare
BWI76_RS17195 -0.7 -1.8 hypothetical protein compare
BWI76_RS00940 -0.7 -2.0 transcriptional regulator HdfR compare
BWI76_RS00025 -0.7 -0.7 hypothetical protein compare
BWI76_RS25870 -0.7 -1.3 elongation factor Tu compare
BWI76_RS17045 -0.7 -1.1 hypothetical protein compare
BWI76_RS18055 -0.6 -1.2 copper resistance protein D compare
BWI76_RS04835 -0.6 -2.3 type II secretion system protein GspE compare
BWI76_RS05450 -0.6 -0.7 ribonuclease HI compare
BWI76_RS01870 -0.6 -2.7 diacylglycerol kinase compare


Specific Phenotypes

For 1 genes in this experiment

For stress 2,2'-Dipyridyl in Klebsiella michiganensis M5al

For stress 2,2'-Dipyridyl across organisms