Protein Info for RR42_RS05665 in Cupriavidus basilensis FW507-4G11

Annotation: urease accessory protein UreJ

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 210 signal peptide" amino acids 1 to 32 (32 residues), see Phobius details transmembrane" amino acids 47 to 70 (24 residues), see Phobius details amino acids 79 to 98 (20 residues), see Phobius details amino acids 104 to 122 (19 residues), see Phobius details amino acids 128 to 145 (18 residues), see Phobius details amino acids 159 to 181 (23 residues), see Phobius details amino acids 191 to 209 (19 residues), see Phobius details PF04955: HupE_UreJ" amino acids 22 to 207 (186 residues), 189.9 bits, see alignment E=1.5e-60

Best Hits

KEGG orthology group: K03192, urease accessory protein (inferred from 74% identity to reh:H16_A1082)

Predicted SEED Role

"HupE-UreJ family metal transporter" in subsystem Transport of Nickel and Cobalt or Urea decomposition

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0C4YCZ8 at UniProt or InterPro

Protein Sequence (210 amino acids)

>RR42_RS05665 urease accessory protein UreJ (Cupriavidus basilensis FW507-4G11)
MNHAEHANRSRAVRLATVGASLALASAAAVAHPGHDATTVGASLFAGLLHPFTGMDHLLA
MVGVGVWSALGARSPREALRMPFAFVALMLAGAVLGLAGMSLALVEPMIAASLLVIGLLV
ALRAKLPAWAGMAIVGGFAVFHGYAHGSELPATAGALPAVAAYVGGFSVATMVLHAAGIG
LGGALRRHAGWLARLAGAGVALYGVGLMVA