Protein Info for RR42_RS04270 in Cupriavidus basilensis FW507-4G11

Annotation: MFS transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 434 transmembrane" amino acids 23 to 41 (19 residues), see Phobius details amino acids 61 to 80 (20 residues), see Phobius details amino acids 92 to 112 (21 residues), see Phobius details amino acids 118 to 141 (24 residues), see Phobius details amino acids 153 to 174 (22 residues), see Phobius details amino acids 186 to 208 (23 residues), see Phobius details amino acids 251 to 272 (22 residues), see Phobius details amino acids 287 to 307 (21 residues), see Phobius details amino acids 318 to 336 (19 residues), see Phobius details amino acids 342 to 362 (21 residues), see Phobius details amino acids 369 to 395 (27 residues), see Phobius details amino acids 410 to 429 (20 residues), see Phobius details PF07690: MFS_1" amino acids 31 to 393 (363 residues), 165.4 bits, see alignment E=9.1e-53

Best Hits

Swiss-Prot: 39% identical to RHMT_ECOLI: Inner membrane transport protein RhmT (rhmT) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 89% identity to reu:Reut_A2617)

Predicted SEED Role

"Nitrate/nitrite transporter" in subsystem Nitrate and nitrite ammonification

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0C4Y5M2 at UniProt or InterPro

Protein Sequence (434 amino acids)

>RR42_RS04270 MFS transporter (Cupriavidus basilensis FW507-4G11)
MTTTAVHSGAADPAFEDATYRKVTLRLVPFLLLCYVVAYLDRVNVGFAKLQMLGDLKFSE
TIYGLGAGIFFIGYFLFEVPSNVILHKVGARIWIARIMITWGVISAAMMFVTTPTMFYVL
RFLLGIAEAGFFPGIILYLTYWYPSHRRGRTTTFFMTAIALSGVIGGPLSGWMMQSFDGR
NGWSGWQWMFLLEGIPSVLVGLVVLAYLDDRIVHAKWLSNEEKALLQRNIAAEDMHKEDA
PIGKVLSSPRVWLMSAIYFSFVMGLYGVSFWLPTIIKQTGVKSPLDIGLLTAIPYGCAVA
GMVLVAYSADRTRERRWHIAIPALLGAVGLVLSVQWHNNTVLALLGLTLATIGILTTLPL
FWSLPTAFLAGTGAAAGIALINSLGNLAGFISPYAVGWLKDMTQSTDSGMYLLAACLVAG
AALTVSVPARMVNK