Protein Info for Psyr_4408 in Pseudomonas syringae pv. syringae B728a

Annotation: Response regulator receiver:ATP-binding region, ATPase-like:Histidine kinase A, N-terminal:Histidine kinase:Histidine kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 900 929 signal peptide" amino acids 1 to 26 (26 residues), see Phobius details transmembrane" amino acids 172 to 189 (18 residues), see Phobius details amino acids 201 to 221 (21 residues), see Phobius details amino acids 234 to 254 (21 residues), see Phobius details amino acids 265 to 282 (18 residues), see Phobius details amino acids 288 to 309 (22 residues), see Phobius details amino acids 320 to 343 (24 residues), see Phobius details amino acids 349 to 369 (21 residues), see Phobius details PF07696: 7TMR-DISMED2" amino acids 29 to 158 (130 residues), 75.7 bits, see alignment E=9.2e-25 PF07695: 7TMR-DISM_7TM" amino acids 172 to 372 (201 residues), 68.1 bits, see alignment E=2.7e-22 PF00512: HisKA" amino acids 396 to 461 (66 residues), 71.2 bits, see alignment 1.5e-23 PF02518: HATPase_c" amino acids 508 to 623 (116 residues), 51.7 bits, see alignment E=2.8e-17 PF00072: Response_reg" amino acids 643 to 759 (117 residues), 69.6 bits, see alignment E=6.3e-23 amino acids 792 to 906 (115 residues), 78.9 bits, see alignment E=8.1e-26

Best Hits

KEGG orthology group: None (inferred from 100% identity to psb:Psyr_4408)

Predicted SEED Role

"Sensor histidine kinase/response regulator"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q4ZN34 at UniProt or InterPro

Protein Sequence (929 amino acids)

>Psyr_4408 Response regulator receiver:ATP-binding region, ATPase-like:Histidine kinase A, N-terminal:Histidine kinase:Histidine kinase (Pseudomonas syringae pv. syringae B728a)
MRWLRIAIASTVGLLTLLFMLSAQAEHGAGWSTLLDEKAHLTLDEIRSARYQNQFSPIEL
ERVTAADRDSALWLHYRLQPTQHEQLLRIFAPDLSSADMYVMDGDRQIDHVRTGNDVPIE
DQRLPSNDFLLPVPQSSAPLDIYLRLVSAQKMRPSITLEPAIASAANETQPLLFGLLFGA
LSMLIVQNLTRYGHTRSRSNLWLAACESLLGLSALLLLNLLRPIDPWNIAQTPSAHLALL
LAAVAGLIYTYCFFVHRNARKLDRLLLGNAVLMGIGALLVLFDEKLPINFLTFGLVSLTT
LSILAVSMWHWQKGYRSARLFVLGMITFNIGYMVVLPGLLWLSLVPPQWLILALLSVFCI
SGVLMSLALSERHRSITEDRFSISRDQAASTAEINAKAEFLAKISHEIRTPMNGVLGMTE
LLLGTPLSVKQRDYVQTIHSAGNELLTLINEILDITKLESGQIELDDVQFDIGALVEDCL
NIFRAKAEQQQVELISQIQPQVPRVINGDPTRLRQTLLSLLENALKKTDEGEILLAVSLE
SSKSGNTRLRISVQDSGESLSDEEREELLHAELHSRNFLASSRLGGHLGLVIARQLIVLM
DGEFGIQNTGAQGNTLWLNLPLDAKLLEQPTIDLDSPLKDARVLVVDDNDTCRKVLVQQC
SAWGLNVSAVASGKEALALLRTKAHLRDYFDVVLLDQNMPGMTGMQLAAKIKEDPSLNHD
ILLIMLTGISNAPSKIIARNSGIKRILAKPVAGYTLKTTLADELTQLNKGVVSNKPGPVV
TPPVNVPGDFRILVAEDNSISTKVIRGMLGKLNLNPDTASNGEEALRAMKAQRYDLVLMD
CEMPILDGFSATEQLRAWEVGNQRVRTPVVALTAHILTEHKDRARQAGMDGHMAKPIELS
QLRELVEHWVAHRDKARGLTSDGEHYRQN