Protein Info for Pf6N2E2_4396 in Pseudomonas fluorescens FW300-N2E2

Annotation: Acetyl-CoA hydrolase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 640 PF13336: AcetylCoA_hyd_C" amino acids 361 to 524 (164 residues), 127.6 bits, see alignment E=2.1e-41

Best Hits

KEGG orthology group: None (inferred from 98% identity to pba:PSEBR_a5503)

Predicted SEED Role

"Acetyl-CoA hydrolase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A160A1P0 at UniProt or InterPro

Protein Sequence (640 amino acids)

>Pf6N2E2_4396 Acetyl-CoA hydrolase (Pseudomonas fluorescens FW300-N2E2)
MVQLCSIEQAVDDVLERLPAHIHLGMPLGLGKPNLFANALYRRIAQLPERQLTIYTALSL
GRPKLGDGLQKRFLEPFVERVFGDYPELDYLADLHQDSLPPNIRVEQFFMQPGSLLHSAS
AQQSYVSSNYSHAARDINAAGLNLVAQLVASDPEHPDRLSLSCNPDITLDLLPMIAKRRA
AGETILLVGQVHNDLPYMPGDAEVGIDAFDLLIDEKDSHTLFSTPNMPVGFQDHLIGLHA
STLVRDGGTLQIGIGAMGDALTAALLARQADNAGYQALLADLNLSQWAQLIEREGGVEPF
AKGLYGCSEMFVNGLLVLAEAGIVRRKVYPDVPTQERANAGTLDEAAQPDGICIHGGFFL
GPRSFYERLRELPQSRLLEFNMTRISYINELYGQEQLKRLQRLDARFINTVFIMTLMGAG
VADQLEDGRVLSGVGGQYNFVAQGHALEGGRSILLLRSWREAGGEISSNIVWDYGHCTIP
RHLRDIVVTEYGIADLRGKTDAAVIEALLNISDSRFQPGLIEQAQKAGKLPKDFRLDPRF
ADNTSERLQAIQARHPNLFPEYPLGCDFDDVERDLLRALNWLKSKFKLTEILELGKAALD
APEPWEFAGHLGRMQLTSPEGLKEELFQRLLLAGLKATAP