Protein Info for MPMX19_06131 in Azospirillum sp. SherDot2

Annotation: Ribose-phosphate pyrophosphokinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR01251: ribose-phosphate diphosphokinase
  • amino acids 16 to 297 (282 residues), 154.7 bits, E=1.3e-49
• PF13793: Pribosyltran_N
  • amino acids 17 to 118 (102 residues), 54.8 bits, E=8.6e-19
• PF00156: Pribosyltran
  • amino acids 161 to 251 (91 residues), 30.4 bits, E=2.4e-11

Best Hits

KEGG orthology group: K00948, ribose-phosphate pyrophosphokinase [EC: 2.7.6.1] (inferred from 90% identity to azl:AZL_e01800)

Predicted SEED Role

"Ribose-phosphate pyrophosphokinase (EC 2.7.6.1)" in subsystem De Novo Purine Biosynthesis or Pentose phosphate pathway (EC 2.7.6.1)

MetaCyc Pathways

• superpathway of histidine, purine, and pyrimidine biosynthesis (44/46 steps found)
• PRPP biosynthesis (1/1 steps found)

KEGG Metabolic Maps

• Biosynthesis of alkaloids derived from histidine and purine
• Biosynthesis of plant hormones
• Pentose phosphate pathway
• Purine metabolism

Isozymes

Compare fitness of predicted isozymes for: 2.7.6.1

Use Curated BLAST to search for 2.7.6.1

Protein Sequence (303 amino acids)

>MPMX19_06131 Ribose-phosphate pyrophosphokinase (Azospirillum sp. SherDot2)
MARNTGNYTAVYGFPESADAARRLAQALEIPCHIAELHRFPDGESLVRLPEPVERAIVYR
SLDRPNDKLVELTLAASVLRRQGATDLCLVAPYMAYMRQDAIFRPGEPVSQTVVGDWLGR
CFDRFVCVEPHLHRTHTLDEVFVGRPSVALSGAAPIAEHLRANGVASGTVIVGPDEESAP
LVEAVAGPLGLTGIVGRKERRGDRDVTVALPPDAPIHGRPVVIVDDVISSGETIFSCARA
ARVLGASRVQVYGVHALFGDIVAERFTAEGLGRPLSCDGVPHPSNALSLSGLLADAIGSL
CTP