Protein Info for MPMX19_02908 in Azospirillum sp. SherDot2

Annotation: Cytochrome c oxidase subunit 1-beta

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 547 transmembrane" amino acids 41 to 62 (22 residues), see Phobius details amino acids 82 to 107 (26 residues), see Phobius details amino acids 123 to 144 (22 residues), see Phobius details amino acids 163 to 187 (25 residues), see Phobius details amino acids 207 to 231 (25 residues), see Phobius details amino acids 256 to 278 (23 residues), see Phobius details amino acids 288 to 310 (23 residues), see Phobius details amino acids 317 to 338 (22 residues), see Phobius details amino acids 359 to 381 (23 residues), see Phobius details amino acids 395 to 416 (22 residues), see Phobius details amino acids 429 to 451 (23 residues), see Phobius details amino acids 470 to 492 (23 residues), see Phobius details TIGR02891: cytochrome c oxidase, subunit I" amino acids 31 to 531 (501 residues), 672.7 bits, see alignment E=1.6e-206 PF00115: COX1" amino acids 39 to 479 (441 residues), 486.9 bits, see alignment E=3e-150

Best Hits

Swiss-Prot: 47% identical to COX1_SYNY3: Cytochrome c oxidase subunit 1 (ctaD) from Synechocystis sp. (strain PCC 6803 / Kazusa)

KEGG orthology group: K02274, cytochrome c oxidase subunit I [EC: 1.9.3.1] (inferred from 70% identity to mpo:Mpop_0025)

MetaCyc: 45% identical to cytochrome c oxidase subunit I (Parasynechococcus marenigrum WH 8102)
RXN-21237 [EC: 7.1.1.9]; 7.1.1.9 [EC: 7.1.1.9]

Predicted SEED Role

"Cytochrome c oxidase polypeptide I (EC 1.9.3.1)" in subsystem Terminal cytochrome C oxidases (EC 1.9.3.1)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.9.3.1

Use Curated BLAST to search for 1.9.3.1 or 7.1.1.9

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (547 amino acids)

>MPMX19_02908 Cytochrome c oxidase subunit 1-beta (Azospirillum sp. SherDot2)
MTTATVTGKPEEPVVATKNYLTEGGVTLRSWLLTRDHKRIAILYTLSITFFFFVGGAAAA
LIRLNLVTPPGIFTPDIYNRLFTLHGVIMVWFFLIPSIPNTMGNFLIPLMIGAKDLAFPR
LNLLSWYLYVGAGFLALFAILIGGVDTGWTFYTPFSSLYSNGYVVLALAAVLAVGFSSIL
TGLNFIVTTHRMRAPGMTWYRLPVFVWSNYATSVIMVLATPVLAITLILVAAERLLKVGI
FDPALGGDPLLFQHLFWFYSHPAVYIMILPGFGVISEIVPCFARKPLFGYKFVVWSSIAI
SVIGFFVWAHHMFVAGISLYAGLVFSLLSYVIAVPSAIKVFNWTATLHKGWISFDAPMLY
ALGFIGLFTIGGLTGLFVANLAFDVHVTDTYFVVAHFHYIMVGGMVSAYFGGLHYWWPKV
TGRLYPEWWARIAALLIFFGFNLTFFPQFILGYLGMERRYYSYPPEFQAWNIFSSAGASV
LAVGYALPFFYLGWSLFRGKRAGANPWAATGLEWQTPSPPPTHNFDRTPTVTRPPYQYRP
EPEPQDV