Protein Info for MPMX19_00966 in Azospirillum sp. SherDot2

Annotation: ATP-dependent zinc metalloprotease FtsH

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 593 signal peptide" amino acids 1 to 27 (27 residues), see Phobius details transmembrane" amino acids 115 to 136 (22 residues), see Phobius details TIGR01241: ATP-dependent metallopeptidase HflB" amino acids 132 to 581 (450 residues), 607.1 bits, see alignment E=1.3e-186 PF00004: AAA" amino acids 190 to 320 (131 residues), 154.8 bits, see alignment E=3.5e-49 PF17862: AAA_lid_3" amino acids 348 to 386 (39 residues), 38.5 bits, see alignment 1.3e-13 PF01434: Peptidase_M41" amino acids 403 to 580 (178 residues), 192.4 bits, see alignment E=1.5e-60

Best Hits

KEGG orthology group: None (inferred from 91% identity to azl:AZL_016470)

Predicted SEED Role

"Cell division protein FtsH (EC 3.4.24.-)" in subsystem Bacterial Cell Division (EC 3.4.24.-)

Isozymes

Compare fitness of predicted isozymes for: 3.4.24.-

Use Curated BLAST to search for 3.4.24.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (593 amino acids)

>MPMX19_00966 ATP-dependent zinc metalloprotease FtsH (Azospirillum sp. SherDot2)
MPTLPKRPLIALAVLAALLAVWLGFAAWYDHHQRADERPATYSALIEQAGRGELGSITFA
NGTGHAVGTDGSRYRVVMPVTDDLLKEMRAHKVAIAFDEGPGGLMAQTVGVLDRAAPFVV
VALLIGGLLMSGGQFFGMGRATRVRPEDTKTVFADVAGVDEAKEELRETVQFLKDPRRFA
MAGARVPKGILLVGPPGTGKTMLAKAAAGEAGVPFFAASGSDFVEMFVGLGAARVRSLFK
TARANAPCILFIDEIDALAGKRGESTSHSEREQTLNQLLVEMDGIVEGGEVVVIAATNRS
EMLDPAVLRPGRFDRHIHVSLPDVAGREAILGVHAGRLTLAPDVCARTVARGTPGFSGAE
LANLTNEAALSAARQGRVIVTMADYEAAKDRVLMGTERRSLALTAHERRLIAVHEAGHAL
VSLRCPQADPIHKATIIPRGGALGMVVRLPEGDRVSVSRAKLMADIAVAMAGRAAEEIAF
GADQVTTGAEADFRAATDLARRMVTAWGMSEEIGFVAHAAAEPGARSERTAWRIDEEVRR
ITDEGMEHARRLLRTDRTALDGIAQALLERETLTGGEIAALADAQTERATEAA