Protein Info for GFF890 in Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868

Annotation: Inosose dehydratase (EC 4.2.1.44)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 301 TIGR04379: myo-inosose-2 dehydratase" amino acids 8 to 296 (289 residues), 387.6 bits, see alignment E=2.2e-120 PF01261: AP_endonuc_2" amino acids 41 to 295 (255 residues), 92.8 bits, see alignment E=1.5e-30

Best Hits

Swiss-Prot: 100% identical to IOLE_SALA4: Inosose dehydratase (iolE) from Salmonella agona (strain SL483)

KEGG orthology group: K03335, inosose dehydratase [EC: 4.2.1.44] (inferred from 100% identity to sea:SeAg_B4706)

MetaCyc: 62% identical to scyllo-inosose dehydratase (Bacillus subtilis subtilis 168)
Myo-inosose-2 dehydratase. [EC: 4.2.1.44]

Predicted SEED Role

"Inosose dehydratase (EC 4.2.1.44)" in subsystem Inositol catabolism (EC 4.2.1.44)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 4.2.1.44

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (301 amino acids)

>GFF890 Inosose dehydratase (EC 4.2.1.44) (Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868)
MYNVKKSIKLGIAPIGWRNDDIPEIGKENTYKQILSDAALTGFSGTEVGGCYPQDPAELN
KELMLRGLEIPGQWFSSFIIRDGIASAMNAFEQHCAYLQAIHAYVAVVSEQTYSIQGIID
KCVYTEKPNFSDSEWQLLCEGLNALGKIANAHGLKLAFHHHMGTGVQTLPEVDRLMENTD
PQFVHLLFDTGHIYVSDGDVMPLLSKHFDRIKHVHFKDVRNEKLKACRLAKKSFLNSFLD
GVFTVPGDGNIDFKSVLAYLVGHQYSGWIVVEAEQDPKKYNPLEYAQKGKKHIDELLKNY
L