Protein Info for GFF5278 in Sphingobium sp. HT1-2

Annotation: GNAT family acetyltransferase PA5433

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 224 PF13302: Acetyltransf_3" amino acids 24 to 161 (138 residues), 64.4 bits, see alignment E=1.9e-21 PF00583: Acetyltransf_1" amino acids 52 to 161 (110 residues), 26.1 bits, see alignment E=8.9e-10

Best Hits

Swiss-Prot: 41% identical to YIW2_YEAST: Uncharacterized protein YIR042C (YIR042C) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c)

KEGG orthology group: None (inferred from 67% identity to mno:Mnod_6844)

Predicted SEED Role

"Protein export cytoplasm protein SecA ATPase RNA helicase (TC 3.A.5.1.1)" (TC 3.A.5.1.1)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (224 amino acids)

>GFF5278 GNAT family acetyltransferase PA5433 (Sphingobium sp. HT1-2)
MSMADWNGAPRPRSVALDGRYARLEPLEPKHSKDLLRSALEAGAEERFRYLFDQPPIDEK
EFADWIERSAASTDPLFFAVVDKATGRAEGRQSLMRIDTTHGVIEIGNILWGPALARTRA
ATEAFYLFASYAFDQLGYRRLEWKCDDRNQPSKRAALRFGFIFEGVFRQHMVVKGENRDT
AWFAITDTEWPGVSAGLQAWLDPANFDDEGGQGRRLEEFQGNEA