Protein Info for ECD_02816 in Escherichia coli BL21

Annotation: KpsD protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 558 signal peptide" amino acids 1 to 21 (21 residues), see Phobius details PF02563: Poly_export" amino acids 88 to 159 (72 residues), 59.7 bits, see alignment E=3.8e-20 PF10531: SLBB" amino acids 461 to 507 (47 residues), 25.1 bits, see alignment 1.9e-09

Best Hits

Swiss-Prot: 99% identical to KPSD1_ECOLX: Polysialic acid transport protein KpsD (kpsD) from Escherichia coli

KEGG orthology group: None (inferred from 99% identity to ecz:ECS88_3323)

Predicted SEED Role

"Capsular polysaccharide export system periplasmic protein KpsD" in subsystem Capsular Polysaccharide (CPS) of Campylobacter

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (558 amino acids)

>ECD_02816 KpsD protein (Escherichia coli BL21)
MKLFKSILLIAACHAAQASAAIDINADPNLTGAAPLTGILNGQQSDTQNMSGFDNTPPPA
PPVVMSRMFGAQLFNGTSADSGATVGFNPDYILNPGDSIQVRLWGAFTFDGALQIDPKGN
IFLPNVGPVKVAGVSNSQLNTLVTSKVKEVYQSNVNVYASLLQAQPVKVYVTGFVRNPGL
YGGVTSDSLLNYLIKAGGVDPERGSYVDIVVKRGNRVRSNVNLYDFLLNGKLGLSQFADG
DTIIVGPRQHTFSVQGDVFNSYDFEFRESSIPVTEALSWARPKPGATHITIMRKQGLQKR
SEYYPISSAPGRMLQNGDTLIVSTDRYAGTIQVRVEGAHSGEHAMVLPYGSTMRAVLEKV
RPNSMSQMNAVQLYRPSVAQRQKEMLNLSLQKLEEASLSAQSSTKEEASLRMQEAQLISR
FVAKARTVVPKGEVILNESNIDSVLLEDGDVINIPEKTSLIMVHGEVLFPNAVSWQKGMT
TEDYIEKCGGLTQKSGNARIIVIRQNGAAVNAEDVDSLKPGDEIMVLPKYESKNIEVTRG
ISTILYQLAVGAKVILSL