Protein Info for BWI76_RS12095 in Klebsiella michiganensis M5al

Annotation: hypothetical protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 306 PF04492: Phage_rep_O" amino acids 20 to 118 (99 residues), 85 bits, see alignment E=2.1e-28 TIGR01610: phage replication protein O, N-terminal domain" amino acids 22 to 118 (97 residues), 120.6 bits, see alignment E=1.5e-39

Best Hits

Swiss-Prot: 66% identical to VG15_BPPH8: Replication protein 15 (15) from Enterobacteria phage phi80

KEGG orthology group: None (inferred from 66% identity to ecd:ECDH10B_1331)

Predicted SEED Role

"Primosomal protein I" in subsystem DNA-replication

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (306 amino acids)

>BWI76_RS12095 hypothetical protein (Klebsiella michiganensis M5al)
MSNTAEVINFPIKTERSGGQMADLANGYTKIANEIQKLKPRLRMSGREWQCLEAVIWLTY
GWNKKQDRVTNTVIAELTDLGESHISDTIKSLAERKIIFAHKQGVMKIVGINTELSEWIL
DKPKTGKLFPESGKVLPKTGKPFPETGDTQYKNKNNSKRSSSSRNSKESRNEETLKFLSR
HPEAAYGIYTPAGKSWGTADDLKAARWIFDKALTVNASLSEPNWVEWANTIRLMRMQDKR
SHYEICELFKWANEDDFWQKNILSPSKLRKQWDQLTTKRLRSPGLSKTTSGASALDNTDW
IDGVLE