Protein Info for ABZR87_RS01400 in Ralstonia sp. UNC404CL21Col

Annotation: DNA polymerase III subunit delta

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 358 TIGR01128: DNA polymerase III, delta subunit" amino acids 20 to 349 (330 residues), 271.5 bits, see alignment E=5.1e-85 PF06144: DNA_pol3_delta" amino acids 24 to 138 (115 residues), 38.5 bits, see alignment E=1.6e-13 PF21694: DNA_pol3_delta_C" amino acids 225 to 326 (102 residues), 36.9 bits, see alignment E=5e-13 PF14840: DNA_pol3_delt_C" amino acids 227 to 326 (100 residues), 36.1 bits, see alignment E=1.1e-12

Best Hits

KEGG orthology group: K02340, DNA polymerase III subunit delta [EC: 2.7.7.7] (inferred from 99% identity to rpi:Rpic_2981)

Predicted SEED Role

"DNA polymerase III delta subunit (EC 2.7.7.7)" in subsystem DNA-replication (EC 2.7.7.7)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.7.7.7

Use Curated BLAST to search for 2.7.7.7

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (358 amino acids)

>ABZR87_RS01400 DNA polymerase III subunit delta (Ralstonia sp. UNC404CL21Col)
MQLRLDALEGHLKQATAKGLAPLYVVHGDEHLLALEAVDALRQAARAQGFTEREVMSVER
GFSWSRVTEARQSMSLFGDRKIVELRIPSGKPGKDGGEALRALAAGTPSGPATDTVTLIT
LPRLDFATAKSAWFAALEGAGVSIKVDSVDRTKLPGWIGERLARQQQRVEPGEPGRRALQ
FIADRVEGNLLAAHQEIQKLGLLHPSGVLTFDDVHDAVLNVARYDVFKLSEAMLAGDVPR
LVRMLEGLRGEGEATVLVLWTLTEEIRVLSKIASGAAQGKPVASMLRELRVWGPRERLVP
QAAQRLSQRELEGALSMAAKLDRQVKGLREPSLPAEPWDGLLQLAMRIARPGSLPVPA