Protein Info for Shew_1021 in Shewanella loihica PV-4

Annotation: peptidase M23B (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 491 transmembrane" amino acids 12 to 33 (22 residues), see Phobius details PF04225: LysM_OapA" amino acids 135 to 195 (61 residues), 27 bits, see alignment E=7.9e-10 PF19425: Csd3_N2" amino acids 228 to 344 (117 residues), 63.8 bits, see alignment E=3e-21 PF01551: Peptidase_M23" amino acids 356 to 450 (95 residues), 109.2 bits, see alignment E=1.9e-35

Best Hits

KEGG orthology group: None (inferred from 100% identity to slo:Shew_1021)

Predicted SEED Role

"Peptidase, M23/M37 family"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A3QBP4 at UniProt or InterPro

Protein Sequence (491 amino acids)

>Shew_1021 peptidase M23B (RefSeq) (Shewanella loihica PV-4)
MGKIITLLKLLPRLHQIILSVLVMITIGAIFIPSDDAEASRSTNTSLTGKIRLGEQAGSG
ASGENTTNDTKTNGYAYPVPLAFRTPEPPSADEIARNTQESGSLDLNGSLDLNESALTQV
TDNPVVEPEEERESSEEFTVRSGDTLAALFKRAGLTARDVYEITQLPKAKKNLLKIMPGE
EIIIVKDDAGQLKRVVYHLDPISTLKICKDDKGYSEEIIKKTVESRTKFASATISSNFWN
AGVGAGLTPNQIMQLATIFGWDIDFALDLRQGDNFAILFEEEYADGEFLRNGNILAAEFY
NQGDRYTAVRYKDGNYYSDEGRSMRKAFLRSPVDFKYVSSSFNPRRLHPVTGQVKAHRGV
DYVAAVGTPIKAAGKGRVIKSGYNQYNGNYVFIKHNETYTTKYLHLKKRKVKQGQTVKQG
QIIGTLGSTGRVTGAHLHYEFIVNGVHRNPRTVKLPQSLPIDSKEKSSFLALSKQLMAKL
EQNKQVQLASQ