Protein Info for Psyr_2968 in Pseudomonas syringae pv. syringae B728a

Annotation: Hydrophobe/amphiphile efflux-1 HAE1

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1063 signal peptide" amino acids 1 to 29 (29 residues), see Phobius details transmembrane" amino acids 342 to 362 (21 residues), see Phobius details amino acids 369 to 389 (21 residues), see Phobius details amino acids 395 to 416 (22 residues), see Phobius details amino acids 440 to 462 (23 residues), see Phobius details amino acids 472 to 499 (28 residues), see Phobius details amino acids 549 to 567 (19 residues), see Phobius details amino acids 881 to 899 (19 residues), see Phobius details amino acids 906 to 928 (23 residues), see Phobius details amino acids 934 to 957 (24 residues), see Phobius details amino acids 982 to 1002 (21 residues), see Phobius details amino acids 1011 to 1037 (27 residues), see Phobius details TIGR00915: RND transporter, hydrophobe/amphiphile efflux-1 (HAE1) family" amino acids 3 to 1054 (1052 residues), 1177.7 bits, see alignment E=0 PF00873: ACR_tran" amino acids 3 to 1038 (1036 residues), 1264.8 bits, see alignment E=0 PF02355: SecD_SecF_C" amino acids 343 to 498 (156 residues), 21.6 bits, see alignment E=2e-08 PF03176: MMPL" amino acids 349 to 498 (150 residues), 37.1 bits, see alignment E=2.8e-13

Best Hits

KEGG orthology group: None (inferred from 84% identity to avn:Avin_33870)

Predicted SEED Role

"Multidrug efflux transporter MexF"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q4ZS70 at UniProt or InterPro

Protein Sequence (1063 amino acids)

>Psyr_2968 Hydrophobe/amphiphile efflux-1 HAE1 (Pseudomonas syringae pv. syringae B728a)
MNFSKFFISRPIFAAVLSLLILIAGAISLFQLPISEYPEVVPPTVVVRANFPGANPKVIG
ETVASPLEQAITGVEGMLYMSSQATADGKLTLTITFALGTDLDNAQVQVQNRVTRSEPKL
PEEVTRIGITVDKASPDLTMVVHLTSPDKRYDMLYLSNYAVLNIKDELARLGGVGDVQLF
GMGDYSLRVWLDPNKTASRNLTATDVVNAIREQNRQVAAGQLGSPPSPNATSFQMSINTQ
GRLVSEEEFENVVVRAGADGEITRLKDIARIELGSSQYALRSLLNNQPAVAIPIFQRPGS
NAIDISNDVRARMAELKQSFPEGMDYSIVYDPTIFVRGSIEAVIHTLFEALILVVLVVIL
FLQTWRASIIPLVAVPVSLIGTFAVMHMFGFSLNALSLFGLVLAIGIVVDDAIVVVENVE
RNIELGLEPVAATHKAMAEVTGPIIATALVLCAVFVPAAFISGLSGQFYKQFALTIAIST
VISAFNSLTLSPALAAVLLKGHDAPKDRFSRFLDKMLGSWLFRPFNRFFEKASHGYVGTV
ARVIRSSGIALLVYAGLMVLTWMGFASTPTGFVPSQDKQYLVAFAQLPDAASLDRTEDVI
KRMSELALKQPGVQDAIAFPGLSINGFTNSPNNGVVFVTLKPFDERKDPSLSANAIAGAL
NGQFASIQEAYMAIFPPPPVQGLGTIGGFRLQIEDRGNLGYDELYKETQNIIAKSRSVPE
LAGLFTSYTVNVPQVDAAIDREKAKTHGVAVSDIFDTLQVYLGSLYANDFNRFGRTYQVN
VQAEQQFRQDADQIGQLKVRNNLGEMIPLATFVKVSDTAGPDRVMHYNGFITAEINGAAA
PGYSSGQAQAAVEKLLREELPTGMIYEWTDLTYQQILSGNTALFVFPLCVLLAFLVLAAQ
YESWSLPLAVILIVPMTLLSAIAGVMIAGSDNNIFTQIGLIVLVGLACKNAILIVEFAKD
KQAEGMSPLDAVLEACRLRLRPILMTSFAFIMGVVPLVLSSGAGAEMRHAMGVAVFSGML
GVTFFGLLLTPVFYVLIRNYVERQEARKAARVNSQQNLPAEMH