Protein Info for GFF3402 in Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868

Annotation: N-acetyl-D-glucosamine kinase (EC 2.7.1.59)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF00480: ROK
  • amino acids 2 to 300 (299 residues), 237.6 bits, E=2.3e-74
• PF02685: Glucokinase
  • amino acids 6 to 255 (250 residues), 27.7 bits, E=1.5e-10

Best Hits

Swiss-Prot: 100% identical to NAGK_SALNS: N-acetyl-D-glucosamine kinase (nagK) from Salmonella newport (strain SL254)

KEGG orthology group: K00884, N-acetylglucosamine kinase [EC: 2.7.1.59] (inferred from 99% identity to stt:t1700)

MetaCyc: 93% identical to N-acetyl-D-glucosamine kinase (Escherichia coli K-12 substr. MG1655)
N-acetylglucosamine kinase. [EC: 2.7.1.59]

Predicted SEED Role

"N-acetyl-D-glucosamine kinase (EC 2.7.1.59)" (EC 2.7.1.59)

MetaCyc Pathways

• N-acetylglucosamine degradation II (3/3 steps found)
• chitin derivatives degradation (4/8 steps found)

KEGG Metabolic Maps

• Aminosugars metabolism
• Nucleotide sugars metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.7.1.59

Protein Sequence (303 amino acids)

>GFF3402 N-acetyl-D-glucosamine kinase (EC 2.7.1.59) (Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868)
MYYGFDIGGTKIALGVFDSTRRLQWEKRVPTPHTSYSAFLDAVCELVEEADQRFGVKGSV
GIGIPGMPETEDGTLYAANVPAASGKPLRADLSARLDRDVRLDNDANCFALSEAWDDEFT
QYPLVMGLILGTGVGGGLVLNGKPITGQSYITGEFGHMRLPVDALTLMGFDFPLRRCGCG
QMGCIENYLSGRGFAWLYQHYYDQSLQAPEIIALWEQGDEQAHAHVERYLDLLAVCLGNI
LTIVDPDLLVIGGGLSNFTAITTQLAERLPRHLLPVARAPRIERARHGDAGGMRGAAFLH
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