Protein Info for EX28DRAFT_1811 in Enterobacter asburiae PDN3

Annotation: Transcriptional regulator/sugar kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF00480: ROK
  • amino acids 2 to 300 (299 residues), 242.6 bits, E=6.7e-76
• PF02685: Glucokinase
  • amino acids 6 to 255 (250 residues), 29.2 bits, E=4.8e-11

Best Hits

Swiss-Prot: 86% identical to NAGK_SALPK: N-acetyl-D-glucosamine kinase (nagK) from Salmonella paratyphi A (strain AKU_12601)

KEGG orthology group: K00884, N-acetylglucosamine kinase [EC: 2.7.1.59] (inferred from 98% identity to enc:ECL_02517)

MetaCyc: 85% identical to N-acetyl-D-glucosamine kinase (Escherichia coli K-12 substr. MG1655)
N-acetylglucosamine kinase. [EC: 2.7.1.59]

Predicted SEED Role

"N-acetyl-D-glucosamine kinase (EC 2.7.1.59)" (EC 2.7.1.59)

MetaCyc Pathways

• N-acetylglucosamine degradation II (3/3 steps found)
• chitin derivatives degradation (4/8 steps found)

KEGG Metabolic Maps

• Aminosugars metabolism
• Nucleotide sugars metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.7.1.59

Protein Sequence (303 amino acids)

>EX28DRAFT_1811 Transcriptional regulator/sugar kinase (Enterobacter asburiae PDN3)
MYYGFDIGGTKIALGVFDKDLRLQWETRVPTPRESYDEFLTAIAALVAQADERFGVKGSV
GIGIPGMPETDDGTLYAANVPAASGKPLRADLSALLERDVRLDNDANCFALSEAWDDEFR
QYPLVMGLILGTGVGGGIVINGKPITGRSYITGEFGHIRLPVDALEVVGRDFPLTRCGCG
QHGCIENYLSGRGFAWLYEHFYHQKLEAPQIITLWEQGDAQACEHVERYLDLLAVCLGNI
LTIVDPDLLVIGGGLSNFTAITERLSGRLPRHLLPVARVPRIERARHGDAGGMRGAAFLH
LTD