Protein Info for BWI76_RS13515 in Klebsiella michiganensis M5al

Annotation: amino acid permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 485 transmembrane" amino acids 37 to 56 (20 residues), see Phobius details amino acids 62 to 85 (24 residues), see Phobius details amino acids 107 to 133 (27 residues), see Phobius details amino acids 145 to 164 (20 residues), see Phobius details amino acids 172 to 193 (22 residues), see Phobius details amino acids 218 to 239 (22 residues), see Phobius details amino acids 260 to 281 (22 residues), see Phobius details amino acids 302 to 325 (24 residues), see Phobius details amino acids 351 to 373 (23 residues), see Phobius details amino acids 380 to 401 (22 residues), see Phobius details amino acids 422 to 442 (21 residues), see Phobius details amino acids 448 to 468 (21 residues), see Phobius details PF13520: AA_permease_2" amino acids 35 to 449 (415 residues), 128.5 bits, see alignment E=3.5e-41 PF00324: AA_permease" amino acids 35 to 475 (441 residues), 460.8 bits, see alignment E=5e-142

Best Hits

Swiss-Prot: 92% identical to ANSP_SALTY: L-asparagine permease (ansP) from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)

KEGG orthology group: K11738, L-asparagine permease (inferred from 96% identity to kpn:KPN_01906)

Predicted SEED Role

"L-asparagine permease"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A285B3C4 at UniProt or InterPro

Protein Sequence (485 amino acids)

>BWI76_RS13515 amino acid permease (Klebsiella michiganensis M5al)
MNTKHSSVAEQHAAKRHWLNSQESGYHKAMGNRQVQMIAIGGAIGTGLFLGAGARLQMAG
PALALVYLVCGLFSFFILRALGELVLHRPSSGSFVSYAREFLGEKAAYVAGWMYFVNWAM
TGIVDITAVALYMHYWGAFGDVPQWVFALGALAIVGTMNMIGVKWFAEMEFWFALVKVLA
IVAFLVVGTIFLGSGKPLDGNATGFHLITDNGGLFPHGLLPALVLVQGVVFAFASIELVG
TAAGECKDPQTMVPRAINSVIWRIGLFYVGSVLLLVLLLPWNAYQAGQSPFVTFFSKLGV
PYIGSVMNIVVLTAALSSLNSGLYCTGRILRSMSMGGSAPKFMSKMSRHHVPYAGILATL
GVYVVGVFLNYLVPSQVFEIVLNVASLGIIASWGFIVVCQMRLRKAIKEGKAADVSFKMP
GAPFTSWLTLLFLLSVLVLMAFDYPNGTYTIGSIPLIAVLLVAGWFGVRKRVHDIHSTAP
NIEKP