Protein Info for ABZR87_RS01545 in Ralstonia sp. UNC404CL21Col

Annotation: L-arabinose ABC transporter ATP-binding protein AraG

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 509 PF00005: ABC_tran" amino acids 35 to 184 (150 residues), 111.6 bits, see alignment E=4.7e-36 amino acids 286 to 438 (153 residues), 75.3 bits, see alignment E=7.8e-25

Best Hits

Swiss-Prot: 76% identical to ARAG2_BURCA: Arabinose import ATP-binding protein AraG 2 (araG2) from Burkholderia cenocepacia (strain AU 1054)

KEGG orthology group: K10539, L-arabinose transport system ATP-binding protein [EC: 3.6.3.17] (inferred from 97% identity to rpf:Rpic12D_2599)

MetaCyc: 52% identical to arabinose ABC transporter ATP binding subunit (Escherichia coli K-12 substr. MG1655)
ABC-2-RXN [EC: 7.5.2.12, 7.5.2.13]

Predicted SEED Role

"L-arabinose transport ATP-binding protein AraG (TC 3.A.1.2.2)" in subsystem L-Arabinose utilization (TC 3.A.1.2.2)

Isozymes

Compare fitness of predicted isozymes for: 3.6.3.17

Use Curated BLAST to search for 3.6.3.17 or 7.5.2.12 or 7.5.2.13

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (509 amino acids)

>ABZR87_RS01545 L-arabinose ABC transporter ATP-binding protein AraG (Ralstonia sp. UNC404CL21Col)
MTVQSLDASGPPDASAGAYLKLDGITVRFPGVLALDHVSLDIRRGEVHGLMGENGAGKST
LLKVLSGVNQPEDGTLSLDGVPQQFTNTRAAIAAGIAIIYQELHLVPELTVAENLMLGAL
PNRFGVLDEKTLIARALRELERLGEKLDPAQAVKHLSIGQRQMIEIGKALMRDARVIAFD
EPTSSLSSRETTQLFRIIRALKAEGRAVIYVTHRMEEVYELCDRVTVFRDGRHIDTFNAG
ANLDRERLIRCMVGRSIQDVYGYKPRPLGGVKVDVRGLIGPGLSEPASFRAHAGEIVGFF
GLVGAGRSELMKLLYGAVKPTAGEIRLNGKRVQFNSPRDAVRAGVALCPEDRKQEGIVAI
ASVSDNLNISCRRHFSRFSVLNNRQEARTTQSFIDKLAIKTRNGETPIGKLSGGNQQKVI
LSRWLAEDIDVFLMDEPTRGIDVGARSEIYSLLYGLAEAGRTVIVVSSDLAEVIGVADRV
LVMKQGRIVGDLPREHASPDTLIKLALPR