Negative cofitness for Rv0444c from Mycobacterium tuberculosis H37Rv

Anti-sigma factor RskA (regulator of sigma K)
SEED: FIG111991: hypothetical protein

Computing cofitness values with 236 experiments...

Genes with the strongest negative cofitness:

Rank	Hit	Name	Description	Cofit
1	Rv3824c		Conserved polyketide synthase associated protein PapA1	-0.33
2	Rv3826		Probable fatty-acid-AMP ligase FadD23 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase)	-0.32
3	Rv2427c		Probable gamma-glutamyl phosphate reductase protein ProA (GPR) (glutamate-5-semialdehyde dehydrogenase) (glutamyl-gamma-semialdehyde dehydrogenase)	-0.31
4	Rv3820c		Possible conserved polyketide synthase associated protein PapA2	-0.31
5	Rv2181		Alpha(1->2)mannosyltransferase	-0.30
6	Rv1564c		Probable maltooligosyltrehalose synthase TreX	-0.30
7	Rv1820		Probable acetolactate synthase IlvG (acetohydroxy-acid synthase)(ALS)	-0.30
8	Rv0474		Probable transcriptional regulatory protein	-0.30
9	Rv0470c		Mycolic acid synthase PcaA (cyclopropane synthase)	-0.30
10	Rv3825c		Polyketide synthase Pks2	-0.29
11	Rv1181		Probable polyketide beta-ketoacyl synthase Pks4	-0.28
12	Rv2557		Conserved protein	-0.27
13	Rv2569c		Conserved hypothetical protein	-0.27
14	Rv2994		Probable conserved integral membrane protein	-0.26
15	Rv1359		Probable transcriptional regulatory protein	-0.26
16	Rv1644		Possible 23S rRNA methyltransferase TsnR	-0.25
17	Rv0448c		Conserved hypothetical protein	-0.25
18	Rv2506		Probable transcriptional regulatory protein (probably TetR-family)	-0.25
19	Rv0353		Probable heat shock protein transcriptional repressor HspR (MerR family)	-0.25
20	Rv1145		Probable conserved transmembrane transport protein MmpL13a	-0.25

Or look for positive cofitness