Negative cofitness for Rv0278c from Mycobacterium tuberculosis H37Rv

PE-PGRS family protein PE_PGRS3
SEED: PE-PGRS FAMILY PROTEIN

Computing cofitness values with 236 experiments...

Genes with the strongest negative cofitness:

Rank Hit Name Description Cofit  
1 Rv1114 Possible toxin VapC32. Contains PIN domain. -0.47
2 Rv0937c DNA end-binding protein, Mku -0.41
3 Rv3450c ESX conserved component EccB4. ESX-4 type VII secretion system protein. Probable membrane protein. -0.39
4 Rv0961 Probable integral membrane protein -0.39
5 Rv2099c PE family protein PE21 -0.37
6 Rv0039c Possible conserved transmembrane protein -0.36
7 Rv2513 Hypothetical protein -0.36
8 Rv0491 Two component sensory transduction protein RegX3 (transcriptional regulatory protein) (probably LuxR-family) -0.35
9 Rv3290c Probable L-lysine-epsilon aminotransferase Lat (L-lysine aminotransferase) (lysine 6-aminotransferase) -0.35
10 Rv1288 Conserved protein -0.34
11 Rv1020 Probable transcription-repair coupling factor Mfd (TRCF) -0.34
12 Rv1527c Probable polyketide synthase Pks5 -0.34
13 Rv0457c Probable peptidase -0.34
14 Rv2315c Conserved protein -0.34
15 Rv2408 Possible PE family-related protein PE24 -0.34
16 Rv1492 Probable methylmalonyl-CoA mutase small subunit MutA (MCM) -0.34
17 Rv0612 Conserved hypothetical protein -0.34
18 Rv1266c Probable transmembrane serine/threonine-protein kinase H PknH (protein kinase H) (STPK H) -0.34
19 Rv0621 Possible membrane protein -0.34
20 Rv0420c Possible transmembrane protein -0.33

Or look for positive cofitness