Conservation of cofitness between Rv0208c and Rv3419c in Mycobacterium tuberculosis H37Rv

83 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Mycobacterium tuberculosis H37Rv 1.0 Rv0208c Hypothetical methlytransferase (methylase) 1.0 Rv3419c Probable O-sialoglycoprotein endopeptidase Gcp (glycoprotease) 0.32 5
Burkholderia phytofirmans PsJN 0.30 BPHYT_RS15470 tRNA (guanine-N(7)-)-methyltransferase 0.32 BPHYT_RS33565 tRNA threonylcarbamoyladenosine modification protein TsaD — —
Paraburkholderia bryophila 376MFSha3.1 0.30 H281DRAFT_04036 tRNA (guanine-N(7)-)-methyltransferase (EC 2.1.1.33) 0.32 H281DRAFT_06013 O-sialoglycoprotein endopeptidase — —
Paraburkholderia graminis OAS925 0.29 ABIE53_003260 tRNA (guanine-N7-)-methyltransferase 0.32 ABIE53_004861 N6-L-threonylcarbamoyladenine synthase — —
Erwinia tracheiphila HP pepo 2.2 0.29 IJEDHG_03485 trmB tRNA (guanosine(46)-N7)-methyltransferase TrmB 0.36 IJEDHG_14345 tsaD tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD — —
Erwinia tracheiphila SCR3 0.29 LU632_RS05425 trmB tRNA (guanosine(46)-N7)-methyltransferase TrmB 0.36 LU632_RS20710 tsaD tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD — —
Castellaniella sp019104865 MT123 0.28 ABCV34_RS08995 tRNA (guanosine(46)-N7)-methyltransferase TrmB 0.32 ABCV34_RS03020 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD — —
Dechlorosoma suillum PS 0.28 Dsui_1016 tRNA (guanine-N(7)-)-methyltransferase 0.37 Dsui_1213 putative glycoprotease GCP — —
Paraburkholderia sabiae LMG 24235 0.28 QEN71_RS03220 tRNA (guanosine(46)-N7)-methyltransferase TrmB 0.33 QEN71_RS15215 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD — —
Rhodanobacter denitrificans MT42 0.28 LRK55_RS11710 tRNA (guanosine(46)-N7)-methyltransferase TrmB 0.36 LRK55_RS06770 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD — —
Pantoea agglomerans CFBP13505 P0401 0.28 PagCFBP13505_RS16130 tRNA (guanosine(46)-N7)-methyltransferase TrmB 0.37 PagCFBP13505_RS11885 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD — —
Rhodanobacter denitrificans FW104-10B01 0.28 LRK54_RS11985 tRNA (guanosine(46)-N7)-methyltransferase TrmB 0.36 LRK54_RS07030 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD — —
Pantoea sp. MT58 0.28 IAI47_03565 tRNA (guanosine(46)-N7)-methyltransferase TrmB 0.37 IAI47_03065 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD — —
Klebsiella pneumoniae MKP103 0.27 KDGMDA_04650 tRNA (guanosine(46)-N7)-methyltransferase TrmB 0.36 KDGMDA_05350 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD — —
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.27 GFF3064 tRNA (guanine46-N7-)-methyltransferase (EC 2.1.1.33) 0.36 GFF3174 TsaD/Kae1/Qri7 protein, required for threonylcarbamoyladenosine t(6)A37 formation in tRNA — —
Klebsiella michiganensis M5al 0.27 BWI76_RS24150 tRNA (guanosine(46)-N7)-methyltransferase TrmB 0.36 BWI76_RS24535 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD — —
Enterobacter asburiae PDN3 0.27 EX28DRAFT_2997 tRNA (guanine-N(7)-)-methyltransferase 0.36 EX28DRAFT_3099 tRNA threonylcarbamoyl adenosine modification protein TsaD — —
Erwinia amylovora T8 0.27 OLJFJH_08500 tRNA (guanosine(46)-N7)-methyltransferase TrmB 0.37 OLJFJH_07600 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD — —
Serratia liquefaciens MT49 0.27 IAI46_21460 tRNA (guanosine(46)-N7)-methyltransferase TrmB 0.36 IAI46_22110 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD — —
Shewanella loihica PV-4 0.27 Shew_1124 trmB tRNA (guanine-N(7))-methyltransferase (RefSeq) 0.36 Shew_1000 metalloendopeptidase glycoprotease family (RefSeq) — —
Shewanella amazonensis SB2B 0.27 Sama_2489 trmB tRNA (guanine-N(7)-)-methyltransferase (RefSeq) 0.34 Sama_0827 O-sialoglycoprotein endopeptidase (RefSeq) — —
Dickeya dadantii 3937 0.27 DDA3937_RS04905 tRNA (guanosine(46)-N7)-methyltransferase TrmB 0.37 DDA3937_RS02960 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD — —
Rhodanobacter sp000427505 FW510-R12 0.27 LRK53_RS16550 tRNA (guanosine(46)-N7)-methyltransferase TrmB 0.36 LRK53_RS01370 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD — —
Rhodanobacter sp. FW510-T8 0.27 OKGIIK_11900 trmB tRNA (guanosine(46)-N7)-methyltransferase TrmB 0.37 OKGIIK_16605 tsaD tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD — —
Rahnella sp. WP5 0.27 EX31_RS02730 tRNA (guanosine(46)-N7)-methyltransferase TrmB 0.36 EX31_RS08180 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD — —
Pseudomonas fluorescens SBW25-INTG 0.26 PFLU_RS28415 tRNA (guanosine(46)-N7)-methyltransferase TrmB 0.36 PFLU_RS27520 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD — —
Pseudomonas fluorescens SBW25 0.26 PFLU_RS28415 tRNA (guanosine(46)-N7)-methyltransferase TrmB 0.36 PFLU_RS27520 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD — —
Enterobacter sp. TBS_079 0.26 MPMX20_03817 tRNA (guanine-N(7)-)-methyltransferase 0.36 MPMX20_03906 tRNA N6-adenosine threonylcarbamoyltransferase — —
Variovorax sp. OAS795 0.26 ABID97_RS18030 tRNA (guanosine(46)-N7)-methyltransferase TrmB 0.32 ABID97_RS20550 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD — —
Dickeya dianthicola 67-19 0.26 HGI48_RS04915 tRNA (guanosine(46)-N7)-methyltransferase TrmB 0.36 HGI48_RS03125 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD — —
Shewanella sp. ANA-3 0.26 Shewana3_1182 trmB tRNA (guanine-N(7)-)-methyltransferase (RefSeq) 0.35 Shewana3_3083 O-sialoglycoprotein endopeptidase (RefSeq) — —
Dickeya dianthicola ME23 0.26 DZA65_RS05250 tRNA (guanosine(46)-N7)-methyltransferase TrmB 0.36 DZA65_RS03120 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD — —
Vibrio cholerae E7946 ATCC 55056 0.26 CSW01_02415 tRNA (guanosine(46)-N7)-methyltransferase TrmB 0.36 CSW01_02765 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD — —
Alteromonas macleodii MIT1002 0.26 MIT1002_00237 tRNA (guanine-N(7)-)-methyltransferase 0.34 MIT1002_00738 t(6)A37 threonylcarbamoyladenosine biosynthesis protein — —
Pseudomonas stutzeri RCH2 0.26 Psest_0268 tRNA (guanine-N(7)-)-methyltransferase 0.37 Psest_3679 putative glycoprotease GCP — —
Herbaspirillum seropedicae SmR1 0.26 HSERO_RS02470 tRNA (guanine-N7)-methyltransferase 0.32 HSERO_RS04280 tRNA threonylcarbamoyladenosine modification protein TsaD — —
Pectobacterium carotovorum WPP14 0.26 HER17_RS16620 tRNA (guanosine(46)-N7)-methyltransferase TrmB 0.37 HER17_RS18400 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD — —
Pseudomonas fluorescens FW300-N1B4 0.26 Pf1N1B4_2332 tRNA (guanine46-N7-)-methyltransferase (EC 2.1.1.33) 0.36 Pf1N1B4_2516 TsaD/Kae1/Qri7 protein, required for threonylcarbamoyladenosine t(6)A37 formation in tRNA — —
Escherichia fergusonii Becca 0.26 EFB2_00942 tRNA (guanine-N(7)-)-methyltransferase 0.35 EFB2_00747 tRNA N6-adenosine threonylcarbamoyltransferase — —
Escherichia coli ECRC102 0.26 NIAGMN_16970 trmB tRNA (guanosine(46)-N7)-methyltransferase TrmB 0.36 NIAGMN_16435 tsaD tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD — —
Escherichia coli HS(pFamp)R (ATCC 700891) 0.26 OHPLBJKB_00756 tRNA (guanine-N(7)-)-methyltransferase 0.36 OHPLBJKB_00638 tRNA N6-adenosine threonylcarbamoyltransferase — —
Escherichia coli ECRC100 0.26 OKFHMN_19205 trmB tRNA (guanosine(46)-N7)-methyltransferase TrmB 0.36 OKFHMN_18670 tsaD tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD — —
Escherichia coli ECRC62 0.26 BNILDI_09650 trmB tRNA (guanosine(46)-N7)-methyltransferase TrmB 0.36 BNILDI_01055 tsaD tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD — —
Escherichia coli ECRC99 0.26 KEDOAH_08935 trmB tRNA (guanosine(46)-N7)-methyltransferase TrmB 0.36 KEDOAH_09475 tsaD tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD — —
Escherichia coli BL21 0.26 ECD_02790 tRNA m(7)G46 methyltransferase, SAM-dependent 0.36 ECD_02934 tRNA(ANN) t(6)A37 threonylcarbamoyladenosine modification protein; glycation binding protein — —
Escherichia coli BW25113 0.26 b2960 yggH tRNA(m7G46)-methyltransferase (NCBI) 0.36 b3064 ygjD O-sialoglycoprotein endopeptidase (NCBI) — —
Escherichia coli Nissle 1917 0.26 ECOLIN_RS16465 tRNA (guanosine(46)-N7)-methyltransferase TrmB 0.36 ECOLIN_RS17690 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD — —
Escherichia coli ECOR27 0.26 NOLOHH_11065 trmB tRNA (guanosine(46)-N7)-methyltransferase TrmB 0.36 NOLOHH_10460 tsaD tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD — —
Shewanella oneidensis MR-1 0.26 SO3367 conserved hypothetical protein TIGR00091 (NCBI ptt file) 0.35 SO1289 gcp O-sialoglycoprotein endopeptidase (NCBI ptt file) — —
Escherichia coli ECRC98 0.26 JDDGAC_22835 trmB tRNA (guanosine(46)-N7)-methyltransferase TrmB 0.36 JDDGAC_22305 tsaD tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD — —
Escherichia coli ECRC101 0.26 MCAODC_09725 trmB tRNA (guanosine(46)-N7)-methyltransferase TrmB 0.36 MCAODC_09185 tsaD tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD — —
Pseudomonas syringae pv. syringae B728a 0.26 Psyr_4739 tRNA (guanine-N(7)-)-methyltransferase 0.35 Psyr_4638 O-sialoglycoprotein endopeptidase — —
Pseudomonas fluorescens GW456-L13 0.26 PfGW456L13_1001 tRNA (guanine46-N7-)-methyltransferase (EC 2.1.1.33) 0.36 PfGW456L13_1189 TsaD/Kae1/Qri7 protein, required for threonylcarbamoyladenosine t(6)A37 formation in tRNA — —
Pseudomonas syringae pv. syringae B728a ΔmexB 0.26 Psyr_4739 tRNA (guanine-N(7)-)-methyltransferase 0.35 Psyr_4638 O-sialoglycoprotein endopeptidase — —
Lysobacter sp. OAE881 0.26 ABIE51_RS16550 tRNA (guanosine(46)-N7)-methyltransferase TrmB 0.35 ABIE51_RS19125 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD — —
Pseudomonas fluorescens FW300-N2E2 0.26 Pf6N2E2_4591 tRNA (guanine46-N7-)-methyltransferase (EC 2.1.1.33) 0.36 Pf6N2E2_4794 TsaD/Kae1/Qri7 protein, required for threonylcarbamoyladenosine t(6)A37 formation in tRNA — —
Pseudomonas fluorescens FW300-N2C3 0.26 AO356_13380 tRNA (guanine-N7)-methyltransferase 0.35 AO356_14280 tRNA threonylcarbamoyl adenosine modification protein TsaD — —
Pseudomonas sp. DMC3 0.25 GFF218 tRNA (guanine-N(7)-)-methyltransferase 0.35 GFF48 tRNA N6-adenosine threonylcarbamoyltransferase — —
Pseudomonas aeruginosa PA14 0.25 IKLFDK_23515 tRNA (guanosine(46)-N7)-methyltransferase TrmB 0.36 IKLFDK_22510 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD — —
Pseudomonas fluorescens FW300-N2E3 0.25 AO353_08210 tRNA (guanine-N7)-methyltransferase 0.36 AO353_07370 tRNA threonylcarbamoyl adenosine modification protein TsaD — —
Kangiella aquimarina DSM 16071 0.25 B158DRAFT_0203 tRNA (guanine-N(7)-)-methyltransferase 0.35 B158DRAFT_0823 putative glycoprotease GCP — —
Pseudomonas simiae WCS417 0.25 PS417_26770 tRNA (guanine-N7)-methyltransferase 0.36 PS417_25865 UGMP family protein — —
Cupriavidus basilensis FW507-4G11 0.25 RR42_RS15625 tRNA (guanine-N7)-methyltransferase 0.32 RR42_RS14995 tRNA threonylcarbamoyladenosine modification protein TsaD — —
Pseudomonas sp. RS175 0.25 PFR28_04251 tRNA (guanine-N(7)-)-methyltransferase 0.35 PFR28_04075 tRNA N6-adenosine threonylcarbamoyltransferase — —
Pseudomonas lactucae CFBP13502 0.25 GEMAOFIL_05491 tRNA (guanine-N(7)-)-methyltransferase 0.35 GEMAOFIL_05293 tRNA N6-adenosine threonylcarbamoyltransferase — —
Escherichia coli ECOR38 0.25 HEPCGN_18475 trmB tRNA (guanosine(46)-N7)-methyltransferase TrmB 0.36 HEPCGN_17525 tsaD tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD — —
Methylophilus sp. DMC18 0.25 GFF1545 tRNA (guanine-N(7)-)-methyltransferase 0.34 GFF2345 tRNA N6-adenosine threonylcarbamoyltransferase — —
Pseudomonas segetis P6 0.25 MPMX49_04406 tRNA (guanine-N(7)-)-methyltransferase 0.35 MPMX49_00867 tRNA N6-adenosine threonylcarbamoyltransferase — —
Marinobacter adhaerens HP15 0.24 HP15_278 tRNA (guanine-N(7)-)-methyltransferase 0.34 HP15_318 metalloendopeptidase, glycoprotease family — —
Acidovorax sp. GW101-3H11 0.24 Ac3H11_4163 tRNA (guanine46-N7-)-methyltransferase (EC 2.1.1.33) 0.33 Ac3H11_3215 TsaD/Kae1/Qri7 protein, required for threonylcarbamoyladenosine t(6)A37 formation in tRNA — —
Variovorax sp. SCN45 0.24 GFF593 tRNA (guanine(46)-N(7))-methyltransferase (EC 2.1.1.33) 0.31 GFF4739 N(6)-L-threonylcarbamoyladenine synthase (EC 2.3.1.234) — —
Dyella japonica UNC79MFTsu3.2 0.24 ABZR86_RS11650 tRNA (guanosine(46)-N7)-methyltransferase TrmB 0.35 ABZR86_RS12800 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD — —
Pseudomonas sp. S08-1 0.24 OH686_14290 tRNA (guanine-N(7)-)-methyltransferase 0.37 OH686_14985 tRNA threonylcarbamoyl adenosine modification protein TsaD — —
Hydrogenophaga sp. GW460-11-11-14-LB1 0.23 GFF5184 tRNA (guanine46-N7-)-methyltransferase (EC 2.1.1.33) 0.34 GFF3673 TsaD/Kae1/Qri7 protein, required for threonylcarbamoyladenosine t(6)A37 formation in tRNA — —
Ralstonia solanacearum UW163 0.23 UW163_RS00810 tRNA (guanosine(46)-N7)-methyltransferase TrmB 0.34 UW163_RS09975 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD — —
Ralstonia solanacearum IBSBF1503 0.23 RALBFv3_RS12755 tRNA (guanosine(46)-N7)-methyltransferase TrmB 0.34 RALBFv3_RS03695 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD — —
Ralstonia sp. UNC404CL21Col 0.22 ABZR87_RS08805 tRNA (guanosine(46)-N7)-methyltransferase TrmB 0.33 ABZR87_RS15625 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD — —
Ralstonia solanacearum GMI1000 0.22 RS_RS03535 tRNA (guanosine(46)-N7)-methyltransferase TrmB 0.34 RS_RS11140 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD — —
Ralstonia solanacearum PSI07 0.22 RPSI07_RS20505 tRNA (guanosine(46)-N7)-methyltransferase TrmB 0.34 RPSI07_RS13535 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD — —
Sphingobium sp. HT1-2 0.18 GFF1611 tRNA (guanine(46)-N(7))-methyltransferase (EC 2.1.1.33) 0.34 GFF3292 N(6)-L-threonylcarbamoyladenine synthase (EC 2.3.1.234) — —
Brevundimonas sp. GW460-12-10-14-LB2 0.16 A4249_RS13980 tRNA (guanosine(46)-N7)-methyltransferase TrmB 0.33 A4249_RS15445 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD — —
Caulobacter crescentus NA1000 0.16 CCNA_00047 tRNA m7-G46 methyltransferase 0.32 CCNA_00069 O-sialoglycoprotein endopeptidase — —
Caulobacter crescentus NA1000 Δfur 0.16 CCNA_00047 tRNA m7-G46 methyltransferase 0.32 CCNA_00069 O-sialoglycoprotein endopeptidase — —
Agrobacterium fabrum C58 0.13 Atu0363 putative tRNA (guanine-N(7)-)-methyltransferase 0.32 Atu2651 O-sialoglycoprotein endopeptidase — —

Not shown: 0 genomes with orthologs for Rv0208c only; 35 genomes with orthologs for Rv3419c only