Conservation of cofitness between Psyr_4683 and Psyr_4684 in Pseudomonas syringae pv. syringae B728a

79 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Pseudomonas syringae pv. syringae B728a 1.0 Psyr_4683 dethiobiotin synthase 1.0 Psyr_4684 biotin synthesis protein BioC 0.72 4
Pseudomonas syringae pv. syringae B728a ΔmexB 1.00 Psyr_4683 dethiobiotin synthase 1.00 Psyr_4684 biotin synthesis protein BioC 0.64 4
Pseudomonas simiae WCS417 0.83 PS417_25985 dethiobiotin synthetase 0.70 PS417_25990 malonyl-CoA O-methyltransferase 0.60 4
Pseudomonas fluorescens SBW25-INTG 0.82 PFLU_RS27630 dethiobiotin synthase 0.72 PFLU_RS27635 malonyl-ACP O-methyltransferase BioC 0.87 3
Pseudomonas fluorescens SBW25 0.82 PFLU_RS27630 dethiobiotin synthase 0.72 PFLU_RS27635 malonyl-ACP O-methyltransferase BioC 0.72 4
Pseudomonas fluorescens FW300-N2E3 0.81 AO353_07505 dethiobiotin synthetase 0.73 AO353_07510 malonyl-[acyl-carrier protein] O-methyltransferase BioC 0.97 1
Pseudomonas orientalis W4I3 0.81 QF045_RS00395 dethiobiotin synthase 0.69 QF045_RS00400 malonyl-ACP O-methyltransferase BioC low > 93
Pseudomonas fluorescens GW456-L13 0.81 PfGW456L13_1151 Dethiobiotin synthetase (EC 6.3.3.3) 0.72 PfGW456L13_1150 Biotin synthesis protein BioC 0.96 3
Pseudomonas lactucae CFBP13502 0.81 GEMAOFIL_05318 ATP-dependent dethiobiotin synthetase BioD 1 0.68 GEMAOFIL_05319 Malonyl-[acyl-carrier protein] O-methyltransferase low > 96
Pseudomonas sp. DMC3 0.80 GFF72 ATP-dependent dethiobiotin synthetase BioD 1 0.70 GFF73 Malonyl-[acyl-carrier protein] O-methyltransferase low > 89
Pseudomonas fluorescens FW300-N1B4 0.80 Pf1N1B4_2491 Dethiobiotin synthetase (EC 6.3.3.3) 0.73 Pf1N1B4_2490 Biotin synthesis protein BioC 0.90 2
Pseudomonas fluorescens FW300-N2E2 0.80 Pf6N2E2_4764 Dethiobiotin synthetase (EC 6.3.3.3) 0.75 Pf6N2E2_4763 Biotin synthesis protein BioC 0.93 1
Pseudomonas fluorescens FW300-N2C3 0.80 AO356_14155 dethiobiotin synthetase 0.75 AO356_14150 malonyl-[acyl-carrier protein] O-methyltransferase BioC 0.88 4
Pseudomonas sp. RS175 0.79 PFR28_04099 ATP-dependent dethiobiotin synthetase BioD 1 0.70 PFR28_04100 Malonyl-[acyl-carrier protein] O-methyltransferase — —
Pseudomonas sp. SVBP6 0.77 COO64_RS22705 bioD dethiobiotin synthase 0.69 COO64_RS22710 bioC malonyl-ACP O-methyltransferase BioC 0.90 29
Pseudomonas segetis P6 0.74 MPMX49_00763 ATP-dependent dethiobiotin synthetase BioD 1 0.69 MPMX49_00762 Malonyl-[acyl-carrier protein] O-methyltransferase 0.87 4
Pseudomonas sp. BP01 0.73 JOY50_RS17950 bioD dethiobiotin synthase 0.65 JOY50_RS17945 bioC malonyl-ACP O-methyltransferase BioC 0.95 13
Pseudomonas putida KT2440 0.72 PP_0366 dethiobiotin synthetase 0.66 PP_0365 Malonyl-[acyl-carrier protein] O-methyltransferase 0.91 3
Pseudomonas sp. S08-1 0.72 OH686_10335 dethiobiotin synthase 0.69 OH686_10340 malonyl-acyl carrier protein O-methyltransferase BioC 0.97 3
Pseudomonas stutzeri RCH2 0.65 Psest_0415 dethiobiotin synthase 0.69 Psest_0414 biotin biosynthesis protein BioC 0.79 5
Pseudomonas aeruginosa MRSN321 0.64 DY961_RS22525 bioD;go_function=dethiobiotin dethiobiotin synthase 0.62 DY961_RS22520 bioC;go_function=malonyl-CoA malonyl-ACP O-methyltransferase BioC — —
Pseudomonas aeruginosa PUPa3 0.64 DQ20_RS36805 bioD;go_function=dethiobiotin dethiobiotin synthase 0.62 DQ20_RS36810 bioC;go_function=malonyl-CoA malonyl-ACP O-methyltransferase BioC — —
Pseudomonas aeruginosa PA14 0.64 IKLFDK_22915 dethiobiotin synthase 0.62 IKLFDK_22920 malonyl-ACP O-methyltransferase BioC 0.85 4
Shewanella loihica PV-4 0.55 Shew_1722 dethiobiotin synthase (RefSeq) 0.18 Shew_1721 methyltransferase type 11 (RefSeq) — —
Shewanella sp. ANA-3 0.53 Shewana3_2516 bioD dithiobiotin synthetase (RefSeq) 0.18 Shewana3_2517 biotin biosynthesis protein BioC (RefSeq) — —
Shewanella oneidensis MR-1 0.52 SO2737 bioD dethiobiotin synthase (NCBI ptt file) 0.18 SO2738 bioC biotin synthesis protein BioC (NCBI ptt file) — —
Marinobacter adhaerens HP15 0.49 HP15_2482 dethiobiotin synthetase 0.25 HP15_2483 protein containing methyltransferase type 11 domain low > 73
Dickeya dianthicola 67-19 0.49 HGI48_RS08690 ATP-dependent dethiobiotin synthetase BioD 0.29 HGI48_RS08685 malonyl-ACP O-methyltransferase BioC low > 71
Dickeya dianthicola ME23 0.49 DZA65_RS08980 ATP-dependent dethiobiotin synthetase BioD 0.29 DZA65_RS08975 malonyl-ACP O-methyltransferase BioC low > 75
Serratia liquefaciens MT49 0.48 IAI46_06540 ATP-dependent dethiobiotin synthetase BioD 0.32 IAI46_06535 malonyl-ACP O-methyltransferase BioC low > 87
Dickeya dadantii 3937 0.48 DDA3937_RS08525 ATP-dependent dethiobiotin synthetase BioD 0.29 DDA3937_RS08520 malonyl-ACP O-methyltransferase BioC low > 74
Pectobacterium carotovorum WPP14 0.48 HER17_RS13445 dethiobiotin synthase 0.29 HER17_RS13450 malonyl-ACP O-methyltransferase BioC low > 75
Enterobacter asburiae PDN3 0.47 EX28DRAFT_2213 dethiobiotin synthase 0.21 EX28DRAFT_2214 malonyl-acyl carrier protein O-methyltransferase BioC low > 76
Enterobacter sp. TBS_079 0.47 MPMX20_01406 ATP-dependent dethiobiotin synthetase BioD 1 0.21 MPMX20_01405 Malonyl-[acyl-carrier protein] O-methyltransferase low > 85
Escherichia coli ECRC99 0.47 KEDOAH_21525 bioD dethiobiotin synthase 0.25 KEDOAH_21520 bioC malonyl-ACP O-methyltransferase BioC — —
Escherichia coli ECRC101 0.47 MCAODC_25600 bioD dethiobiotin synthase 0.25 MCAODC_25605 bioC malonyl-ACP O-methyltransferase BioC 0.38 28
Escherichia coli ECRC98 0.47 JDDGAC_10020 bioD dethiobiotin synthase 0.25 JDDGAC_10025 bioC malonyl-ACP O-methyltransferase BioC low > 87
Escherichia coli ECRC100 0.47 OKFHMN_06385 bioD dethiobiotin synthase 0.25 OKFHMN_06390 bioC malonyl-ACP O-methyltransferase BioC low > 79
Escherichia coli ECRC102 0.47 NIAGMN_04430 bioD dethiobiotin synthase 0.25 NIAGMN_04435 bioC malonyl-ACP O-methyltransferase BioC 0.91 4
Escherichia coli HS(pFamp)R (ATCC 700891) 0.47 OHPLBJKB_02935 ATP-dependent dethiobiotin synthetase BioD 1 0.24 OHPLBJKB_02936 Malonyl-[acyl-carrier protein] O-methyltransferase low > 74
Escherichia coli BL21 0.47 ECD_00745 dethiobiotin synthetase 0.24 ECD_00744 malonyl-ACP O-methyltransferase, SAM-dependent low > 61
Escherichia fergusonii Becca 0.46 EFB2_03327 ATP-dependent dethiobiotin synthetase BioD 1 0.24 EFB2_03328 Malonyl-[acyl-carrier protein] O-methyltransferase low > 86
Escherichia coli Nissle 1917 0.46 ECOLIN_RS04145 dethiobiotin synthase 0.24 ECOLIN_RS04140 malonyl-ACP O-methyltransferase BioC — —
Escherichia coli BW25113 0.46 b0778 bioD dethiobiotin synthetase (NCBI) 0.24 b0777 bioC predicted methltransferase, enzyme of biotin synthesis (NCBI) 0.35 5
Pantoea agglomerans CFBP13505 P0401 0.46 PagCFBP13505_RS03785 ATP-dependent dethiobiotin synthetase BioD 0.28 PagCFBP13505_RS03780 malonyl-ACP O-methyltransferase BioC low > 74
Escherichia coli ECOR38 0.46 HEPCGN_01655 bioD dethiobiotin synthase 0.24 HEPCGN_01650 bioC malonyl-ACP O-methyltransferase BioC low > 88
Pantoea sp. MT58 0.46 IAI47_13515 ATP-dependent dethiobiotin synthetase BioD 0.26 IAI47_13520 malonyl-ACP O-methyltransferase BioC low > 76
Escherichia coli ECOR27 0.46 NOLOHH_22755 bioD dethiobiotin synthase 0.23 NOLOHH_22760 bioC malonyl-ACP O-methyltransferase BioC low > 76
Escherichia coli ECRC62 0.45 BNILDI_21025 bioD dethiobiotin synthase 0.24 BNILDI_21030 bioC malonyl-ACP O-methyltransferase BioC 0.55 61
Klebsiella pneumoniae MKP103 0.45 KDGMDA_17040 dethiobiotin synthase 0.23 KDGMDA_17035 malonyl-ACP O-methyltransferase BioC 0.34 57
Shewanella amazonensis SB2B 0.44 Sama_1441 bioD dithiobiotin synthetase (RefSeq) 0.18 Sama_1440 biotin synthesis protein BioC (RefSeq) — —
Klebsiella michiganensis M5al 0.44 BWI76_RS08775 dethiobiotin synthase 0.22 BWI76_RS08770 malonyl-ACP O-methyltransferase BioC 0.19 56
Dyella japonica UNC79MFTsu3.2 0.44 ABZR86_RS12700 dethiobiotin synthase 0.28 ABZR86_RS15820 malonyl-ACP O-methyltransferase BioC — —
Rahnella sp. WP5 0.44 EX31_RS23710 ATP-dependent dethiobiotin synthetase BioD 0.29 EX31_RS23705 malonyl-ACP O-methyltransferase BioC low > 89
Erwinia tracheiphila SCR3 0.44 LU632_RS09145 bioD dethiobiotin synthase 0.26 LU632_RS09140 bioC malonyl-ACP O-methyltransferase BioC — —
Erwinia tracheiphila HP pepo 2.2 0.43 IJEDHG_19580 bioD dethiobiotin synthase 0.26 IJEDHG_19575 bioC malonyl-ACP O-methyltransferase BioC — —
Lysobacter sp. OAE881 0.43 ABIE51_RS17990 dethiobiotin synthase 0.28 ABIE51_RS01160 malonyl-ACP O-methyltransferase BioC — —
Rhodanobacter sp. FW510-T8 0.42 OKGIIK_16455 bioD dethiobiotin synthase 0.30 OKGIIK_13670 bioC malonyl-ACP O-methyltransferase BioC — —
Rhodanobacter sp000427505 FW510-R12 0.42 LRK53_RS01195 dethiobiotin synthase 0.30 LRK53_RS03020 malonyl-ACP O-methyltransferase BioC — —
Rhodanobacter denitrificans FW104-10B01 0.42 LRK54_RS07180 dethiobiotin synthase 0.29 LRK54_RS10240 malonyl-ACP O-methyltransferase BioC — —
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.41 GFF674 Dethiobiotin synthetase (EC 6.3.3.3) 0.23 GFF673 Biotin synthesis protein BioC low > 78
Dechlorosoma suillum PS 0.41 Dsui_2884 dethiobiotin synthase 0.26 Dsui_2883 biotin biosynthesis protein BioC 0.91 1
Rhodanobacter denitrificans MT42 0.41 LRK55_RS06915 dethiobiotin synthase 0.29 LRK55_RS09880 malonyl-ACP O-methyltransferase BioC — —
Erwinia amylovora T8 0.41 OLJFJH_16745 dethiobiotin synthase 0.23 OLJFJH_16750 malonyl-ACP O-methyltransferase BioC low > 58
Kangiella aquimarina DSM 16071 0.40 B158DRAFT_0869 dethiobiotin synthase 0.31 B158DRAFT_0867 biotin biosynthesis protein BioC — —
Vibrio cholerae E7946 ATCC 55056 0.38 CSW01_05660 dethiobiotin synthase 0.30 CSW01_05655 malonyl-[acyl-carrier protein] O-methyltransferase BioC low > 62
Burkholderia phytofirmans PsJN 0.37 BPHYT_RS02155 dithiobiotin synthetase 0.13 BPHYT_RS02630 amidophosphoribosyltransferase — —
Herbaspirillum seropedicae SmR1 0.36 HSERO_RS12255 dethiobiotin synthetase 0.14 HSERO_RS20805 methyltransferase — —
Ralstonia sp. UNC404CL21Col 0.35 ABZR87_RS12345 dethiobiotin synthase 0.12 ABZR87_RS06785 methyltransferase domain-containing protein — —
Ralstonia solanacearum PSI07 0.35 RPSI07_RS16695 dethiobiotin synthase 0.12 RPSI07_RS22375 SAM-dependent methyltransferase — —
Paraburkholderia bryophila 376MFSha3.1 0.35 H281DRAFT_02096 dethiobiotin synthetase 0.14 H281DRAFT_01996 malonyl-CoA O-methyltransferase — —
Ralstonia solanacearum IBSBF1503 0.35 RALBFv3_RS00825 dethiobiotin synthase 0.13 RALBFv3_RS10935 SAM-dependent methyltransferase — —
Ralstonia solanacearum UW163 0.35 UW163_RS14160 dethiobiotin synthase 0.13 UW163_RS02645 SAM-dependent methyltransferase — —
Xanthomonas campestris pv. campestris strain 8004 0.34 Xcc-8004.4530.1 Dethiobiotin synthetase (EC 6.3.3.3) 0.23 Xcc-8004.498.1 Biotin synthesis protein BioC — —
Ralstonia solanacearum GMI1000 0.34 RS_RS07440 ATP-dependent dethiobiotin synthetase BioD 0.12 RS_RS01775 SAM-dependent methyltransferase — —
Methylophilus sp. DMC18 0.32 GFF1686 ATP-dependent dethiobiotin synthetase BioD 1 0.32 GFF1685 Malonyl-[acyl-carrier protein] O-methyltransferase — —
Paraburkholderia sabiae LMG 24235 0.29 QEN71_RS01090 dethiobiotin synthase 0.15 QEN71_RS01485 methyltransferase domain-containing protein — —
Cupriavidus basilensis FW507-4G11 0.27 RR42_RS00935 dethiobiotin synthetase 0.16 RR42_RS01865 amidophosphoribosyltransferase — —
Sphingobium sp. HT1-2 0.17 GFF3209 Dethiobiotin synthase BioD (EC 6.3.3.3) 0.14 GFF2407 Malonyl-[acyl-carrier protein] O-methyltransferase (EC 2.1.1.197) low > 95
Phaeobacter inhibens DSM 17395 0.16 PGA1_c09140 dethiobiotin synthetase BioD 0.11 PGA1_c09170 putative biotin synthesis protein BioC 0.54 3

Not shown: 20 genomes with orthologs for Psyr_4683 only; 6 genomes with orthologs for Psyr_4684 only