| Organism | Ratio1 | Gene1 | Name1 | Description1 | Ratio2 | Gene2 | Name2 | Description2 | Cofit | Rank |
| Azospirillum sp. SherDot2 | 1.0 | MPMX19_00635 | | 5,10-methylenetetrahydrofolate reductase | 1.0 | MPMX19_00653 | | hypothetical protein | 0.85 | 11 |
| Azospirillum brasilense Sp245 | 0.90 | AZOBR_RS09540 | | 5 10-methylenetetrahydrofolate reductase | 0.79 | AZOBR_RS10120 | | hypothetical protein | — | — |
| Xanthobacter sp. DMC5 | 0.64 | GFF4147 | | 5,10-methylenetetrahydrofolate reductase | 0.35 | GFF2388 | | hypothetical protein | — | — |
| Rhodopseudomonas palustris CGA009 | 0.57 | TX73_019175 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.34 | TX73_021835 | | DUF934 domain-containing protein | low | > 86 |
| Caulobacter crescentus NA1000 Δfur | 0.57 | CCNA_02224 | | methylenetetrahydrofolate reductase | 0.34 | CCNA_01178 | | conserved hypothetical protein, DUF934 | low | > 67 |
| Caulobacter crescentus NA1000 | 0.57 | CCNA_02224 | | methylenetetrahydrofolate reductase | 0.34 | CCNA_01178 | | conserved hypothetical protein, DUF934 | 0.87 | 58 |
| Marinobacter adhaerens HP15 | 0.39 | HP15_2917 | | 5,10-methylenetetrahydrofolate reductase-like protein | 0.27 | HP15_1796 | | required for sulfate utilization, putative electron transport protein for sulfite reductase (from data) | 0.73 | 42 |
| Pseudomonas stutzeri RCH2 | 0.39 | Psest_0313 | | 5,10-methylenetetrahydrofolate reductase, prokaryotic form | 0.31 | Psest_2088 | | Uncharacterized protein conserved in bacteria | 0.58 | 44 |
| Pseudomonas fluorescens FW300-N1B4 | 0.38 | Pf1N1B4_2384 | | 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) | 0.31 | Pf1N1B4_5666 | | Oxidoreductase probably involved in sulfite reduction | 0.84 | 24 |
| Pseudomonas aeruginosa PA14 | 0.38 | IKLFDK_23270 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.35 | IKLFDK_08935 | | DUF934 domain-containing protein | low | > 100 |
| Ralstonia sp. UNC404CL21Col | 0.38 | ABZR87_RS04865 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.29 | ABZR87_RS00205 | | DUF934 domain-containing protein | 0.60 | 43 |
| Pseudomonas sp. DMC3 | 0.38 | GFF171 | | 5,10-methylenetetrahydrofolate reductase | 0.30 | GFF3693 | | hypothetical protein | 0.86 | 68 |
| Pseudomonas fluorescens SBW25-INTG | 0.38 | PFLU_RS28165 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.31 | PFLU_RS12975 | | DUF934 domain-containing protein | 0.53 | 29 |
| Ralstonia solanacearum UW163 | 0.38 | UW163_RS03705 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.26 | UW163_RS09075 | | DUF934 domain-containing protein | — | — |
| Pseudomonas fluorescens SBW25 | 0.38 | PFLU_RS28165 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.31 | PFLU_RS12975 | | DUF934 domain-containing protein | low | > 109 |
| Ralstonia solanacearum IBSBF1503 | 0.38 | RALBFv3_RS09875 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.26 | RALBFv3_RS04595 | | DUF934 domain-containing protein | — | — |
| Paraburkholderia bryophila 376MFSha3.1 | 0.38 | H281DRAFT_05801 | | 5,10-methylenetetrahydrofolate reductase (NAD(P)) | 0.32 | H281DRAFT_00115 | | Uncharacterized conserved protein, DUF934 family | 0.47 | 35 |
| Pseudomonas lactucae CFBP13502 | 0.38 | GEMAOFIL_05433 | | 5,10-methylenetetrahydrofolate reductase | 0.31 | GEMAOFIL_02702 | | hypothetical protein | low | > 93 |
| Pseudomonas fluorescens GW456-L13 | 0.38 | PfGW456L13_1050 | | 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) | 0.30 | PfGW456L13_2842 | | required for sulfate utilization, putative electron transport protein for sulfite reductase (from data) | 0.93 | 9 |
| Pseudomonas putida KT2440 | 0.37 | PP_4977 | | 5,10-methylenetetrahydrofolate reductase | 0.31 | PP_2370 | | conserved protein of unknown function | 0.43 | 56 |
| Pseudomonas simiae WCS417 | 0.37 | PS417_26510 | | 5,10-methylenetetrahydrofolate reductase | 0.31 | PS417_12285 | | oxidoreductase | — | — |
| Pseudomonas fluorescens FW300-N2E2 | 0.37 | Pf6N2E2_4638 | | 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) | 0.29 | Pf6N2E2_2074 | | required for sulfate utilization, putative electron transport protein for sulfite reductase (from data) | 0.46 | 50 |
| Pseudomonas fluorescens FW300-N2E3 | 0.37 | AO353_08015 | | 5,10-methylenetetrahydrofolate reductase | 0.31 | AO353_22795 | | oxidoreductase | — | — |
| Pseudomonas sp. S08-1 | 0.37 | OH686_10820 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.29 | OH686_03475 | | Oxidoreductase putative | low | > 80 |
| Pseudomonas syringae pv. syringae B728a ΔmexB | 0.37 | Psyr_0459 | | 5,10-methylenetetrahydrofolate reductase | 0.32 | Psyr_2461 | | Uncharacterized conserved protein UCP030820 | — | — |
| Pseudomonas syringae pv. syringae B728a | 0.37 | Psyr_0459 | | 5,10-methylenetetrahydrofolate reductase | 0.32 | Psyr_2461 | | Uncharacterized conserved protein UCP030820 | 0.43 | 59 |
| Pseudomonas sp. SVBP6 | 0.37 | COO64_RS17485 | metF | methylenetetrahydrofolate reductase [NAD(P)H] | 0.28 | COO64_RS24890 | | DUF934 domain-containing protein | 0.73 | 86 |
| Pseudomonas sp. BP01 | 0.37 | JOY50_RS09810 | metF | methylenetetrahydrofolate reductase [NAD(P)H] | 0.31 | JOY50_RS10740 | | DUF934 domain-containing protein | 0.85 | 80 |
| Paraburkholderia graminis OAS925 | 0.37 | ABIE53_000061 | | methylenetetrahydrofolate reductase (NADPH) | 0.33 | ABIE53_001227 | | uncharacterized protein (DUF934 family) | 0.74 | 19 |
| Dechlorosoma suillum PS | 0.37 | Dsui_0640 | | 5,10-methylenetetrahydrofolate reductase | 0.30 | Dsui_1985 | | hypothetical protein | — | — |
| Pseudomonas sp. RS175 | 0.37 | PFR28_04202 | | 5,10-methylenetetrahydrofolate reductase | 0.30 | PFR28_01365 | | hypothetical protein | 0.63 | 18 |
| Pseudomonas fluorescens FW300-N2C3 | 0.37 | AO356_13605 | | 5,10-methylenetetrahydrofolate reductase | 0.29 | AO356_00560 | | required for sulfate utilization, putative electron transport protein for sulfite reductase (from data) | 0.86 | 37 |
| Burkholderia phytofirmans PsJN | 0.37 | BPHYT_RS18705 | | 5,10-methylenetetrahydrofolate reductase | 0.31 | BPHYT_RS04730 | | required for sulfate utilization, putative electron transport protein for sulfite reductase (from data) | 0.54 | 16 |
| Pseudomonas segetis P6 | 0.37 | MPMX49_00645 | | 5,10-methylenetetrahydrofolate reductase | 0.31 | MPMX49_02598 | | hypothetical protein | low | > 75 |
| Herbaspirillum seropedicae SmR1 | 0.33 | HSERO_RS21425 | | 5,10-methylenetetrahydrofolate reductase | 0.31 | HSERO_RS15555 | | oxidoreductase | low | > 78 |
| Acinetobacter baumannii LAC-4 | 0.33 | RR41_RS05725 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.17 | RR41_RS03250 | | DUF934 domain-containing protein | low | > 55 |
Not shown: 80 genomes with orthologs for MPMX19_00635 only; 0 genomes with orthologs for MPMX19_00653 only