Conservation of cofitness between GFF403 and GFF952 in Sphingobium sp. HT1-2

82 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Sphingobium sp. HT1-2 1.0 GFF403 Aspartate aminotransferase (EC 2.6.1.1) 1.0 GFF952 Gamma-glutamyl phosphate reductase (EC 1.2.1.41) 0.79 45
Sphingomonas koreensis DSMZ 15582 0.73 Ga0059261_2226 Aspartate/tyrosine/aromatic aminotransferase 0.67 Ga0059261_2506 glutamate-5-semialdehyde dehydrogenase (EC 1.2.1.41) 0.97 31
Caulobacter crescentus NA1000 Δfur 0.62 CCNA_01603 aspartate aminotransferase 0.51 CCNA_03543 gamma-glutamyl phosphate reductase low > 67
Caulobacter crescentus NA1000 0.62 CCNA_01603 aspartate aminotransferase 0.51 CCNA_03543 gamma-glutamyl phosphate reductase low > 66
Azospirillum sp. SherDot2 0.62 MPMX19_02392 Aspartate/prephenate aminotransferase 0.56 MPMX19_01943 Gamma-glutamyl phosphate reductase — —
Azospirillum brasilense Sp245 0.62 AZOBR_RS12970 aspartate aminotransferase 0.56 AZOBR_RS04075 gamma-glutamyl phosphate reductase — —
Xanthobacter sp. DMC5 0.60 GFF4663 Aspartate/prephenate aminotransferase 0.57 GFF3946 Gamma-glutamyl phosphate reductase — —
Brevundimonas sp. GW460-12-10-14-LB2 0.59 A4249_RS04680 pyridoxal phosphate-dependent aminotransferase 0.46 A4249_RS16120 glutamate-5-semialdehyde dehydrogenase — —
Dinoroseobacter shibae DFL-12 0.59 Dshi_0762 aminotransferase class I and II (RefSeq) 0.50 Dshi_1469 gamma-glutamyl phosphate reductase (RefSeq) — —
Rhodospirillum rubrum S1H 0.59 Rru_A1135 Aminotransferase, class I and II (NCBI) 0.57 Rru_A1238 Gamma-glutamyl phosphate reductase GPR (NCBI) — —
Phaeobacter inhibens DSM 17395 0.58 PGA1_c21250 aspartate aminotransferase AatA 0.49 PGA1_c15520 gamma-glutamyl phosphate reductase ProA 0.48 50
Rhodopseudomonas palustris CGA009 0.58 TX73_022440 pyridoxal phosphate-dependent aminotransferase 0.56 TX73_000855 glutamate-5-semialdehyde dehydrogenase — —
Rhizobium sp. OAE497 0.57 ABIE40_RS12925 pyridoxal phosphate-dependent aminotransferase 0.55 ABIE40_RS18925 glutamate-5-semialdehyde dehydrogenase 0.91 6
Sinorhizobium meliloti 1021 0.57 SMc01578 aspartate aminotransferase 0.56 SMc03777 gamma-glutamyl phosphate reductase 0.74 5
Bosea sp. OAE506 0.56 ABIE41_RS11765 pyridoxal phosphate-dependent aminotransferase 0.47 ABIE41_RS07580 glutamate-5-semialdehyde dehydrogenase — —
Agrobacterium fabrum C58 0.56 Atu2196 aspartate aminotransferase A 0.55 Atu2779 gamma-glutamyl phosphate reductase — —
Magnetospirillum magneticum AMB-1 0.53 AMB_RS02875 pyridoxal phosphate-dependent aminotransferase 0.62 AMB_RS20640 glutamate-5-semialdehyde dehydrogenase — —
Pseudomonas fluorescens SBW25-INTG 0.53 PFLU_RS15480 pyridoxal phosphate-dependent aminotransferase 0.47 PFLU_RS26675 glutamate-5-semialdehyde dehydrogenase — —
Pseudomonas fluorescens SBW25 0.53 PFLU_RS15480 pyridoxal phosphate-dependent aminotransferase 0.47 PFLU_RS26675 glutamate-5-semialdehyde dehydrogenase — —
Pseudomonas fluorescens FW300-N1B4 0.52 Pf1N1B4_5070 Aspartate aminotransferase (EC 2.6.1.1) 0.49 Pf1N1B4_2688 Gamma-glutamyl phosphate reductase (EC 1.2.1.41) low > 87
Pseudomonas fluorescens FW300-N2C3 0.52 AO356_25355 aspartate aminotransferase 0.49 AO356_15290 gamma-glutamyl phosphate reductase low > 104
Ralstonia solanacearum GMI1000 0.52 RS_RS23085 pyridoxal phosphate-dependent aminotransferase 0.46 RS_RS13715 gamma-glutamyl-phosphate reductase — —
Variovorax sp. SCN45 0.51 GFF5025 Aspartate aminotransferase (EC 2.6.1.1) 0.45 GFF6326 Gamma-glutamyl phosphate reductase (EC 1.2.1.41) low > 127
Acidovorax sp. GW101-3H11 0.51 Ac3H11_1602 Aspartate aminotransferase (EC 2.6.1.1) 0.43 Ac3H11_704 Gamma-glutamyl phosphate reductase (EC 1.2.1.41) low > 79
Ralstonia solanacearum PSI07 0.51 RPSI07_RS05665 pyridoxal phosphate-dependent aminotransferase 0.47 RPSI07_RS11475 glutamate-5-semialdehyde dehydrogenase low > 81
Cupriavidus basilensis FW507-4G11 0.50 RR42_RS35305 aspartate aminotransferase 0.44 RR42_RS17530 gamma-glutamyl phosphate reductase low > 128
Variovorax sp. OAS795 0.50 ABID97_RS04080 pyridoxal phosphate-dependent aminotransferase 0.44 ABID97_RS04600 glutamate-5-semialdehyde dehydrogenase — —
Pseudomonas sp. BP01 0.50 JOY50_RS13660 pyridoxal phosphate-dependent aminotransferase 0.45 JOY50_RS17680 glutamate-5-semialdehyde dehydrogenase low > 84
Ralstonia solanacearum UW163 0.49 UW163_RS21205 pyridoxal phosphate-dependent aminotransferase 0.47 UW163_RS07800 glutamate-5-semialdehyde dehydrogenase — —
Ralstonia solanacearum IBSBF1503 0.49 RALBFv3_RS17935 pyridoxal phosphate-dependent aminotransferase 0.47 RALBFv3_RS05825 glutamate-5-semialdehyde dehydrogenase low > 76
Rahnella sp. WP5 0.48 EX31_RS17525 pyridoxal phosphate-dependent aminotransferase 0.39 EX31_RS20975 glutamate-5-semialdehyde dehydrogenase low > 89
Acinetobacter baumannii LAC-4 0.48 RR41_RS04925 pyridoxal phosphate-dependent aminotransferase 0.49 RR41_RS16505 glutamate-5-semialdehyde dehydrogenase low > 55
Pseudomonas simiae WCS417 0.48 PS417_19025 aspartate aminotransferase 0.46 PS417_24745 gamma-glutamyl phosphate reductase low > 88
Bacteroides thetaiotaomicron VPI-5482 0.47 BT2415 aspartate aminotransferase (NCBI ptt file) 0.38 BT3718 gamma-glutamyl phosphate reductase (NCBI ptt file) 0.62 59
Phocaeicola vulgatus CL09T03C04 0.47 HMPREF1058_RS00785 pyridoxal phosphate-dependent aminotransferase 0.34 HMPREF1058_RS08645 glutamate-5-semialdehyde dehydrogenase — —
Parabacteroides merdae CL09T00C40 0.47 HMPREF1078_RS12080 pyridoxal phosphate-dependent aminotransferase 0.35 HMPREF1078_RS10655 glutamate-5-semialdehyde dehydrogenase 0.84 41
Dickeya dianthicola ME23 0.47 DZA65_RS19800 pyridoxal phosphate-dependent aminotransferase 0.38 DZA65_RS17690 glutamate-5-semialdehyde dehydrogenase low > 75
Phocaeicola dorei CL03T12C01 0.47 ABI39_RS00770 pyridoxal phosphate-dependent aminotransferase 0.34 ABI39_RS02875 glutamate-5-semialdehyde dehydrogenase 0.82 15
Bacteroides stercoris CC31F 0.47 HMPREF1181_RS03765 pyridoxal phosphate-dependent aminotransferase 0.37 HMPREF1181_RS03320 glutamate-5-semialdehyde dehydrogenase 0.77 36
Dickeya dianthicola 67-19 0.47 HGI48_RS18665 pyridoxal phosphate-dependent aminotransferase 0.39 HGI48_RS16600 glutamate-5-semialdehyde dehydrogenase low > 71
Acinetobacter radioresistens SK82 0.46 MPMX26_02146 Aspartate/prephenate aminotransferase 0.51 MPMX26_00417 Gamma-glutamyl phosphate reductase low > 36
Methylophilus sp. DMC18 0.46 GFF1121 Aspartate/prephenate aminotransferase 0.50 GFF254 Gamma-glutamyl phosphate reductase — —
Klebsiella michiganensis M5al 0.46 BWI76_RS10245 aspartate aminotransferase 0.40 BWI76_RS05835 gamma-glutamyl-phosphate reductase low > 92
Marinobacter adhaerens HP15 0.46 HP15_1371 aspartate aminotransferase 0.50 HP15_601 gamma-glutamyl phosphate reductase — —
Bacteroides ovatus ATCC 8483 0.46 BACOVA_03005 aminotransferase, class I/II 0.38 BACOVA_03534 glutamate-5-semialdehyde dehydrogenase 0.68 55
Dickeya dadantii 3937 0.46 DDA3937_RS08230 pyridoxal phosphate-dependent aminotransferase 0.39 DDA3937_RS16530 glutamate-5-semialdehyde dehydrogenase low > 74
Cellulophaga baltica 18 0.45 M666_RS08600 pyridoxal phosphate-dependent aminotransferase 0.29 M666_RS02645 glutamate-5-semialdehyde dehydrogenase low > 67
Kangiella aquimarina DSM 16071 0.45 B158DRAFT_2340 Aspartate/tyrosine/aromatic aminotransferase 0.39 B158DRAFT_1470 glutamate-5-semialdehyde dehydrogenase (EC 1.2.1.41) low > 40
Pseudomonas lactucae CFBP13502 0.45 GEMAOFIL_01711 Aspartate/prephenate aminotransferase 0.47 GEMAOFIL_05102 Gamma-glutamyl phosphate reductase — —
Pseudomonas fluorescens FW300-N2E2 0.42 Pf6N2E2_1496 Aspartate aminotransferase (EC 2.6.1.1) 0.49 Pf6N2E2_4993 Gamma-glutamyl phosphate reductase (EC 1.2.1.41) low > 103
Synechococcus elongatus PCC 7942 0.42 Synpcc7942_2545 aspC aspartate aminotransferase 0.33 Synpcc7942_2265 proA glutamate-5-semialdehyde dehydrogenase — —
Mucilaginibacter yixingensis YX-36 DSM 26809 0.40 ABZR88_RS15900 pyridoxal phosphate-dependent aminotransferase 0.36 ABZR88_RS22165 glutamate-5-semialdehyde dehydrogenase 0.89 3
Desulfovibrio vulgaris Miyazaki F 0.39 DvMF_2204 aminotransferase class I and II (RefSeq) 0.40 DvMF_0612 proA gamma-glutamyl phosphate reductase (RefSeq) low > 51
Echinicola vietnamensis KMM 6221, DSM 17526 0.38 Echvi_0675 Aspartate/tyrosine/aromatic aminotransferase 0.28 Echvi_2633 gamma-glutamylphosphate reductase (EC 1.2.1.41) (from data) — —
Pedobacter sp. GW460-11-11-14-LB5 0.38 CA265_RS07515 pyridoxal phosphate-dependent aminotransferase 0.37 CA265_RS20850 glutamate-5-semialdehyde dehydrogenase 0.72 7
Synechocystis sp000284455 PCC 6803 0.38 SGL_RS13785 pyridoxal phosphate-dependent aminotransferase 0.35 SGL_RS14505 glutamate-5-semialdehyde dehydrogenase — —
Desulfovibrio vulgaris Hildenborough JW710 0.37 DVU3223 aspB aspartate aminotransferase (TIGR) 0.40 DVU1953 proA gamma-glutamyl phosphate reductase (TIGR) low > 55
Pontibacter actiniarum KMM 6156, DSM 19842 0.37 CA264_01120 aspartate aminotransferase 0.38 CA264_07720 gamma-glutamyl-phosphate reductase — —
Bifidobacterium breve UCC2003 0.33 BBR_RS19435 pyridoxal phosphate-dependent aminotransferase 0.38 BBR_RS14075 glutamate-5-semialdehyde dehydrogenase low > 34
Lysobacter sp. OAE881 0.31 ABIE51_RS06000 pyridoxal phosphate-dependent aminotransferase 0.43 ABIE51_RS13365 glutamate-5-semialdehyde dehydrogenase low > 62
Rhodanobacter denitrificans FW104-10B01 0.31 LRK54_RS00725 pyridoxal phosphate-dependent aminotransferase 0.43 LRK54_RS02370 glutamate-5-semialdehyde dehydrogenase low > 59
Rhodanobacter denitrificans MT42 0.31 LRK55_RS00500 pyridoxal phosphate-dependent aminotransferase 0.43 LRK55_RS02125 glutamate-5-semialdehyde dehydrogenase low > 63
Rhodanobacter sp. FW510-T8 0.31 OKGIIK_06525 aspB aminotransferase 0.40 OKGIIK_09415 proA glutamate-5-semialdehyde dehydrogenase low > 53
Dyella japonica UNC79MFTsu3.2 0.30 ABZR86_RS08550 pyridoxal phosphate-dependent aminotransferase 0.43 ABZR86_RS08680 glutamate-5-semialdehyde dehydrogenase low > 74
Rhodanobacter sp000427505 FW510-R12 0.29 LRK53_RS09430 aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme 0.42 LRK53_RS07575 glutamate-5-semialdehyde dehydrogenase low > 59
Pseudomonas sp. RS175 0.22 PFR28_02468 Arginine--pyruvate transaminase AruH 0.49 PFR28_03872 Gamma-glutamyl phosphate reductase — —
Pseudomonas putida KT2440 0.22 PP_3721 arginine:pyruvate transaminase AruH (EC 2.6.1.84) (from data) 0.47 PP_4811 Gamma-glutamyl phosphate reductase 0.13 90
Pseudomonas fluorescens GW456-L13 0.22 PfGW456L13_3206 Aspartate aminotransferase (EC 2.6.1.1) 0.48 PfGW456L13_1356 Gamma-glutamyl phosphate reductase (EC 1.2.1.41) low > 87
Pseudomonas aeruginosa PA14 0.21 IKLFDK_28660 Arginine--pyruvate transaminase AruH 0.46 IKLFDK_20665 glutamate-5-semialdehyde dehydrogenase low > 100
Burkholderia phytofirmans PsJN 0.21 BPHYT_RS27000 aspartate aminotransferase 0.46 BPHYT_RS16770 gamma-glutamyl phosphate reductase — —
Pseudomonas sp. SVBP6 0.21 COO64_RS20990 pyridoxal phosphate-dependent aminotransferase 0.48 COO64_RS15630 glutamate-5-semialdehyde dehydrogenase low > 93
Pseudomonas sp. DMC3 0.21 GFF2929 Arginine--pyruvate transaminase AruH 0.48 GFF3876 Gamma-glutamyl phosphate reductase low > 89
Mycobacterium tuberculosis H37Rv 0.17 Rv0337c Probable aspartate aminotransferase AspC (transaminase A) (ASPAT) 0.37 Rv2427c Probable gamma-glutamyl phosphate reductase protein ProA (GPR) (glutamate-5-semialdehyde dehydrogenase) (glutamyl-gamma-semialdehyde dehydrogenase) — —
Alteromonas macleodii MIT1002 0.16 MIT1002_02306 Glutamate-pyruvate aminotransferase AlaA 0.41 MIT1002_01885 Gamma-glutamyl phosphate reductase 0.79 36
Erwinia amylovora T8 0.15 OLJFJH_11400 Glutamate-pyruvate aminotransferase AlaA 0.39 OLJFJH_18405 glutamate-5-semialdehyde dehydrogenase low > 58
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.15 GFF1894 Aspartate aminotransferase (EC 2.6.1.1) 0.41 GFF4115 Gamma-glutamyl phosphate reductase (EC 1.2.1.41) low > 78
Erwinia tracheiphila SCR3 0.14 LU632_RS07955 pyridoxal phosphate-dependent aminotransferase 0.38 LU632_RS01190 proA glutamate-5-semialdehyde dehydrogenase 0.80 11
Vibrio cholerae E7946 ATCC 55056 0.14 CSW01_09870 pyridoxal phosphate-dependent aminotransferase 0.40 CSW01_11570 glutamate-5-semialdehyde dehydrogenase low > 62
Erwinia tracheiphila HP pepo 2.2 0.14 IJEDHG_18035 aspB aminotransferase 0.38 IJEDHG_15495 proA glutamate-5-semialdehyde dehydrogenase low > 61
Shewanella amazonensis SB2B 0.13 Sama_1697 aminotransferase AlaT (RefSeq) 0.37 Sama_2515 proA gamma-glutamyl phosphate reductase (RefSeq) 0.49 51
Shewanella sp. ANA-3 0.12 Shewana3_2145 aminotransferase AlaT (RefSeq) 0.42 Shewana3_4057 glutamate-5-semialdehyde dehydrogenase (RefSeq) low > 73
Shewanella oneidensis MR-1 0.12 SO2483 aspartate aminotransferase, putative (NCBI ptt file) 0.39 SO1122 proA gamma-glutamyl phosphate reductase (NCBI ptt file) 0.42 45
Shewanella loihica PV-4 0.12 Shew_1914 aminotransferase AlaT (RefSeq) 0.40 Shew_2847 proA gamma-glutamyl phosphate reductase (RefSeq) low > 60

Not shown: 2 genomes with orthologs for GFF403 only; 35 genomes with orthologs for GFF952 only