Conservation of cofitness between GFF403 and GFF3455 in Sphingobium sp. HT1-2

76 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Sphingobium sp. HT1-2 1.0 GFF403 Aspartate aminotransferase (EC 2.6.1.1) 1.0 GFF3455 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) @ O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) 0.83 29
Sphingomonas koreensis DSMZ 15582 0.73 Ga0059261_2226 Aspartate/tyrosine/aromatic aminotransferase 0.80 Ga0059261_3194 O-acetylhomoserine sulfhydrylase (EC:2.5.1.49) (from data) 0.90 54
Caulobacter crescentus NA1000 Δfur 0.62 CCNA_01603 aspartate aminotransferase 0.50 CCNA_02321 O-succinylhomoserine sulfhydrylase low > 67
Caulobacter crescentus NA1000 0.62 CCNA_01603 aspartate aminotransferase 0.50 CCNA_02321 O-succinylhomoserine sulfhydrylase 0.81 62
Azospirillum sp. SherDot2 0.62 MPMX19_02392 Aspartate/prephenate aminotransferase 0.47 MPMX19_01364 O-succinylhomoserine sulfhydrylase low > 112
Azospirillum brasilense Sp245 0.62 AZOBR_RS12970 aspartate aminotransferase 0.45 AZOBR_RS02140 O-succinylhomoserine sulfhydrylase — —
Xanthobacter sp. DMC5 0.60 GFF4663 Aspartate/prephenate aminotransferase 0.51 GFF4634 O-succinylhomoserine sulfhydrylase — —
Brevundimonas sp. GW460-12-10-14-LB2 0.59 A4249_RS04680 pyridoxal phosphate-dependent aminotransferase 0.29 A4249_RS08315 cystathionine gamma-synthase — —
Dinoroseobacter shibae DFL-12 0.59 Dshi_0762 aminotransferase class I and II (RefSeq) 0.47 Dshi_2410 O-succinylhomoserine sulfhydrylase (RefSeq) — —
Rhodospirillum rubrum S1H 0.59 Rru_A1135 Aminotransferase, class I and II (NCBI) 0.50 Rru_A3214 O-succinylhomoserine sulfhydrylase (NCBI) — —
Phaeobacter inhibens DSM 17395 0.58 PGA1_c21250 aspartate aminotransferase AatA 0.48 PGA1_c23540 O-succinylhomoserine sulfhydrylase MetZ 0.50 44
Rhodopseudomonas palustris CGA009 0.58 TX73_022440 pyridoxal phosphate-dependent aminotransferase 0.50 TX73_024775 O-succinylhomoserine sulfhydrylase — —
Rhizobium sp. OAE497 0.57 ABIE40_RS12925 pyridoxal phosphate-dependent aminotransferase 0.53 ABIE40_RS02340 O-succinylhomoserine sulfhydrylase 0.89 14
Sinorhizobium meliloti 1021 0.57 SMc01578 aspartate aminotransferase 0.54 SMc02217 O-succinylhomoserine sulfhydrylase 0.69 32
Bosea sp. OAE506 0.56 ABIE41_RS11765 pyridoxal phosphate-dependent aminotransferase 0.50 ABIE41_RS03970 O-succinylhomoserine sulfhydrylase — —
Agrobacterium fabrum C58 0.56 Atu2196 aspartate aminotransferase A 0.53 Atu0432 O-succinylhomoserine sulfhydrylase — —
Magnetospirillum magneticum AMB-1 0.53 AMB_RS02875 pyridoxal phosphate-dependent aminotransferase 0.56 AMB_RS21365 O-succinylhomoserine sulfhydrylase — —
Pseudomonas fluorescens SBW25 0.53 PFLU_RS15480 pyridoxal phosphate-dependent aminotransferase 0.41 PFLU_RS20510 O-succinylhomoserine sulfhydrylase low > 109
Pseudomonas fluorescens SBW25-INTG 0.53 PFLU_RS15480 pyridoxal phosphate-dependent aminotransferase 0.41 PFLU_RS20510 O-succinylhomoserine sulfhydrylase low > 109
Pseudomonas fluorescens FW300-N2C3 0.52 AO356_25355 aspartate aminotransferase 0.40 AO356_21470 O-succinylhomoserine sulfhydrylase low > 104
Ralstonia solanacearum GMI1000 0.52 RS_RS23085 pyridoxal phosphate-dependent aminotransferase 0.31 RS_RS07865 O-acetylhomoserine aminocarboxypropyltransferase low > 80
Variovorax sp. SCN45 0.51 GFF5025 Aspartate aminotransferase (EC 2.6.1.1) 0.42 GFF3088 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) @ O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) — —
Acidovorax sp. GW101-3H11 0.51 Ac3H11_1602 Aspartate aminotransferase (EC 2.6.1.1) 0.32 Ac3H11_2928 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) low > 79
Ralstonia solanacearum PSI07 0.51 RPSI07_RS05665 pyridoxal phosphate-dependent aminotransferase 0.31 RPSI07_RS15620 O-acetylhomoserine aminocarboxypropyltransferase low > 81
Cupriavidus basilensis FW507-4G11 0.50 RR42_RS35305 aspartate aminotransferase 0.44 RR42_RS14320 O-succinylhomoserine sulfhydrylase low > 128
Variovorax sp. OAS795 0.50 ABID97_RS04080 pyridoxal phosphate-dependent aminotransferase 0.42 ABID97_RS21630 O-succinylhomoserine sulfhydrylase — —
Pseudomonas sp. BP01 0.50 JOY50_RS13660 pyridoxal phosphate-dependent aminotransferase 0.40 JOY50_RS16560 O-succinylhomoserine sulfhydrylase low > 84
Ralstonia solanacearum IBSBF1503 0.49 RALBFv3_RS17935 pyridoxal phosphate-dependent aminotransferase 0.31 RALBFv3_RS01870 O-acetylhomoserine aminocarboxypropyltransferase low > 76
Ralstonia solanacearum UW163 0.49 UW163_RS21205 pyridoxal phosphate-dependent aminotransferase 0.31 UW163_RS15180 O-acetylhomoserine aminocarboxypropyltransferase — —
Rahnella sp. WP5 0.48 EX31_RS17525 pyridoxal phosphate-dependent aminotransferase 0.34 EX31_RS04985 PLP-dependent transferase low > 89
Acinetobacter baumannii LAC-4 0.48 RR41_RS04925 pyridoxal phosphate-dependent aminotransferase 0.42 RR41_RS12630 O-succinylhomoserine sulfhydrylase low > 55
Pseudomonas simiae WCS417 0.48 PS417_19025 aspartate aminotransferase 0.40 PS417_18530 O-succinylhomoserine sulfhydrylase low > 88
Bacteroides thetaiotaomicron VPI-5482 0.47 BT2415 aspartate aminotransferase (NCBI ptt file) 0.36 BT2387 O-acetylhomoserine (thiol)-lyase (NCBI ptt file) low > 81
Phocaeicola vulgatus CL09T03C04 0.47 HMPREF1058_RS00785 pyridoxal phosphate-dependent aminotransferase 0.35 HMPREF1058_RS17635 O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase — —
Parabacteroides merdae CL09T00C40 0.47 HMPREF1078_RS12080 pyridoxal phosphate-dependent aminotransferase 0.29 HMPREF1078_RS07330 O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase low > 61
Dickeya dianthicola ME23 0.47 DZA65_RS19800 pyridoxal phosphate-dependent aminotransferase 0.27 DZA65_RS21470 cystathionine gamma-synthase low > 75
Phocaeicola dorei CL03T12C01 0.47 ABI39_RS00770 pyridoxal phosphate-dependent aminotransferase 0.36 ABI39_RS13825 O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase low > 72
Bacteroides stercoris CC31F 0.47 HMPREF1181_RS03765 pyridoxal phosphate-dependent aminotransferase 0.35 HMPREF1181_RS05290 O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase low > 56
Dickeya dianthicola 67-19 0.47 HGI48_RS18665 pyridoxal phosphate-dependent aminotransferase 0.28 HGI48_RS20425 cystathionine gamma-synthase low > 71
Acinetobacter radioresistens SK82 0.46 MPMX26_02146 Aspartate/prephenate aminotransferase 0.42 MPMX26_01645 O-succinylhomoserine sulfhydrylase low > 36
Methylophilus sp. DMC18 0.46 GFF1121 Aspartate/prephenate aminotransferase 0.41 GFF662 O-succinylhomoserine sulfhydrylase — —
Klebsiella michiganensis M5al 0.46 BWI76_RS10245 aspartate aminotransferase 0.29 BWI76_RS24210 cystathionine gamma-lyase low > 92
Bacteroides ovatus ATCC 8483 0.46 BACOVA_03005 aminotransferase, class I/II 0.36 BACOVA_03030 O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase low > 96
Marinobacter adhaerens HP15 0.46 HP15_1371 aspartate aminotransferase 0.36 HP15_1820 methionine gamma-lyase — —
Dickeya dadantii 3937 0.46 DDA3937_RS08230 pyridoxal phosphate-dependent aminotransferase 0.27 DDA3937_RS00950 cystathionine gamma-synthase low > 74
Cellulophaga baltica 18 0.45 M666_RS08600 pyridoxal phosphate-dependent aminotransferase 0.40 M666_RS08150 aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme low > 67
Kangiella aquimarina DSM 16071 0.45 B158DRAFT_2340 Aspartate/tyrosine/aromatic aminotransferase 0.39 B158DRAFT_1522 methionine gamma-lyase low > 40
Pseudomonas lactucae CFBP13502 0.45 GEMAOFIL_01711 Aspartate/prephenate aminotransferase 0.40 GEMAOFIL_03934 O-succinylhomoserine sulfhydrylase low > 93
Pseudomonas fluorescens FW300-N2E2 0.42 Pf6N2E2_1496 Aspartate aminotransferase (EC 2.6.1.1) 0.40 Pf6N2E2_77 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) low > 103
Synechococcus elongatus PCC 7942 0.42 Synpcc7942_2545 aspC aspartate aminotransferase 0.26 Synpcc7942_0370 metY O-acetylhomoserine/O-acetylserine sulfhydrylase — —
Pedobacter sp. GW460-11-11-14-LB5 0.38 CA265_RS07515 pyridoxal phosphate-dependent aminotransferase 0.41 CA265_RS13080 O-succinylhomoserine sulfhydrylase 0.70 26
Echinicola vietnamensis KMM 6221, DSM 17526 0.38 Echvi_0675 Aspartate/tyrosine/aromatic aminotransferase 0.41 Echvi_2283 Cystathionine beta-lyases/cystathionine gamma-synthases — —
Pontibacter actiniarum KMM 6156, DSM 19842 0.37 CA264_01120 aspartate aminotransferase 0.40 CA264_02530 O-succinylhomoserine sulfhydrylase — —
Bifidobacterium breve UCC2003 0.33 BBR_RS19435 pyridoxal phosphate-dependent aminotransferase 0.30 BBR_RS14595 O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase low > 34
Lysobacter sp. OAE881 0.31 ABIE51_RS06000 pyridoxal phosphate-dependent aminotransferase 0.30 ABIE51_RS04295 cystathionine gamma-synthase low > 62
Rhodanobacter denitrificans MT42 0.31 LRK55_RS00500 pyridoxal phosphate-dependent aminotransferase 0.28 LRK55_RS05410 cystathionine gamma-synthase low > 63
Rhodanobacter denitrificans FW104-10B01 0.31 LRK54_RS00725 pyridoxal phosphate-dependent aminotransferase 0.27 LRK54_RS05660 PLP-dependent aspartate aminotransferase family protein low > 59
Rhodanobacter sp. FW510-T8 0.31 OKGIIK_06525 aspB aminotransferase 0.28 OKGIIK_01180 metC cystathionine beta-lyase low > 53
Dyella japonica UNC79MFTsu3.2 0.30 ABZR86_RS08550 pyridoxal phosphate-dependent aminotransferase 0.29 ABZR86_RS18745 PLP-dependent aspartate aminotransferase family protein — —
Rhodanobacter sp000427505 FW510-R12 0.29 LRK53_RS09430 aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme 0.28 LRK53_RS04370 cystathionine gamma-synthase low > 59
Pseudomonas sp. RS175 0.22 PFR28_02468 Arginine--pyruvate transaminase AruH 0.40 PFR28_02810 O-succinylhomoserine sulfhydrylase low > 88
Pseudomonas putida KT2440 0.22 PP_3721 arginine:pyruvate transaminase AruH (EC 2.6.1.84) (from data) 0.39 PP_2001 O-succinylhomoserine sulfhydrylase low > 96
Pseudomonas fluorescens GW456-L13 0.22 PfGW456L13_3206 Aspartate aminotransferase (EC 2.6.1.1) 0.40 PfGW456L13_3934 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) low > 87
Pseudomonas aeruginosa PA14 0.21 IKLFDK_28660 Arginine--pyruvate transaminase AruH 0.40 IKLFDK_15810 O-succinylhomoserine sulfhydrylase low > 100
Burkholderia phytofirmans PsJN 0.21 BPHYT_RS27000 aspartate aminotransferase 0.47 BPHYT_RS33835 O-succinylhomoserine sulfhydrylase low > 109
Pseudomonas sp. SVBP6 0.21 COO64_RS20990 pyridoxal phosphate-dependent aminotransferase 0.40 COO64_RS05595 O-succinylhomoserine sulfhydrylase low > 93
Pseudomonas sp. DMC3 0.21 GFF2929 Arginine--pyruvate transaminase AruH 0.41 GFF799 O-succinylhomoserine sulfhydrylase low > 89
Mycobacterium tuberculosis H37Rv 0.17 Rv0337c Probable aspartate aminotransferase AspC (transaminase A) (ASPAT) 0.44 Rv0391 Probable O-succinylhomoserine sulfhydrylase MetZ (OSH sulfhydrylase) — —
Alteromonas macleodii MIT1002 0.16 MIT1002_02306 Glutamate-pyruvate aminotransferase AlaA 0.25 MIT1002_02266 Methionine gamma-lyase 0.76 44
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.15 GFF1894 Aspartate aminotransferase (EC 2.6.1.1) 0.26 GFF2323 Cystathionine gamma-synthase (EC 2.5.1.48) low > 78
Erwinia tracheiphila SCR3 0.14 LU632_RS07955 pyridoxal phosphate-dependent aminotransferase 0.26 LU632_RS19640 metB cystathionine gamma-synthase 0.82 7
Vibrio cholerae E7946 ATCC 55056 0.14 CSW01_09870 pyridoxal phosphate-dependent aminotransferase 0.27 CSW01_13550 O-succinylhomoserine (thiol)-lyase low > 62
Erwinia tracheiphila HP pepo 2.2 0.14 IJEDHG_18035 aspB aminotransferase 0.26 IJEDHG_13020 metB cystathionine gamma-synthase low > 61
Shewanella amazonensis SB2B 0.13 Sama_1697 aminotransferase AlaT (RefSeq) 0.39 Sama_1242 methionine gamma-lyase (RefSeq) low > 62
Shewanella sp. ANA-3 0.12 Shewana3_2145 aminotransferase AlaT (RefSeq) 0.39 Shewana3_2643 methionine gamma-lyase (RefSeq) low > 73
Shewanella oneidensis MR-1 0.12 SO2483 aspartate aminotransferase, putative (NCBI ptt file) 0.40 SO1812 mdeA Methionine gamma-lyase (EC 4.4.1.11) (from data) low > 76
Shewanella loihica PV-4 0.12 Shew_1914 aminotransferase AlaT (RefSeq) 0.39 Shew_2491 methionine gamma-lyase (RefSeq) low > 60

Not shown: 8 genomes with orthologs for GFF403 only; 35 genomes with orthologs for GFF3455 only