Conservation of cofitness between GFF4271 and GFF2842 in Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868

35 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 1.0 GFF4271 Penicillin-binding protein AmpH 1.0 GFF2842 Transcriptional regulator KdgR, KDG operon repressor 0.43 15
Escherichia coli Nissle 1917 0.93 ECOLIN_RS02290 D-alanyl-D-alanine- carboxypeptidase/endopeptidase AmpH 0.96 ECOLIN_RS10175 DNA-binding transcriptional regulator KdgR — —
Escherichia fergusonii Becca 0.93 EFB2_03681 D-alanyl-D-alanine- carboxypeptidase/endopeptidase AmpH 0.96 EFB2_02174 Transcriptional regulator KdgR low > 86
Escherichia coli ECRC101 0.93 MCAODC_27890 ampH D-alanyl-D-alanine-carboxypeptidase/endopeptidase AmpH 0.96 MCAODC_18925 kdgR DNA-binding transcriptional regulator KdgR low > 88
Escherichia coli ECRC100 0.93 OKFHMN_08665 ampH D-alanyl-D-alanine-carboxypeptidase/endopeptidase AmpH 0.96 OKFHMN_26480 kdgR DNA-binding transcriptional regulator KdgR low > 79
Escherichia coli ECOR38 0.93 HEPCGN_07305 ampH D-alanyl-D-alanine-carboxypeptidase/endopeptidase AmpH 0.96 HEPCGN_04880 kdgR DNA-binding transcriptional regulator KdgR low > 88
Escherichia coli ECRC98 0.93 JDDGAC_12320 ampH D-alanyl-D-alanine-carboxypeptidase/endopeptidase AmpH 0.96 JDDGAC_01055 kdgR DNA-binding transcriptional regulator KdgR low > 87
Escherichia coli ECRC102 0.93 NIAGMN_06720 ampH D-alanyl-D-alanine-carboxypeptidase/endopeptidase AmpH 0.96 NIAGMN_01580 kdgR DNA-binding transcriptional regulator KdgR low > 80
Escherichia coli ECRC99 0.93 KEDOAH_19305 ampH D-alanyl-D-alanine-carboxypeptidase/endopeptidase AmpH 0.96 KEDOAH_01625 kdgR DNA-binding transcriptional regulator KdgR — —
Escherichia coli ECRC62 0.93 BNILDI_23000 ampH D-alanyl-D-alanine-carboxypeptidase/endopeptidase AmpH 0.96 BNILDI_15785 kdgR DNA-binding transcriptional regulator KdgR low > 75
Escherichia coli BW25113 0.93 b0376 ampH beta-lactamase/D-alanine carboxypeptidase (NCBI) 0.96 b1827 kdgR predicted DNA-binding transcriptional regulator (NCBI) low > 76
Escherichia coli HS(pFamp)R (ATCC 700891) 0.93 OHPLBJKB_03299 D-alanyl-D-alanine- carboxypeptidase/endopeptidase AmpH 0.96 OHPLBJKB_01904 Transcriptional regulator KdgR low > 74
Escherichia coli BL21 0.92 ECD_00323 D-alanyl-D-alanine- carboxypeptidase/endopeptidase; penicillin-binding protein; weak beta-lactamase 0.96 ECD_01798 KDG regulon transcriptional repressor low > 61
Klebsiella michiganensis M5al 0.88 BWI76_RS06095 D-alanyl-D-alanine- carboxypeptidase/endopeptidase AmpH 0.94 BWI76_RS17960 DNA-binding transcriptional regulator KdgR — —
Enterobacter sp. TBS_079 0.87 MPMX20_00963 D-alanyl-D-alanine- carboxypeptidase/endopeptidase AmpH 0.94 MPMX20_02734 Transcriptional regulator KdgR low > 85
Enterobacter asburiae PDN3 0.87 EX28DRAFT_2598 Beta-lactamase class C and other penicillin binding proteins 0.95 EX28DRAFT_0729 transcriptional regulator, IclR family low > 76
Klebsiella pneumoniae MKP103 0.85 KDGMDA_14190 D-alanyl-D-alanine-carboxypeptidase/endopeptidase AmpH 0.94 KDGMDA_25230 DNA-binding transcriptional regulator KdgR low > 95
Pantoea sp. MT58 0.74 IAI47_05345 D-alanyl-D-alanine- carboxypeptidase/endopeptidase AmpH 0.85 IAI47_08720 DNA-binding transcriptional regulator KdgR low > 76
Pantoea agglomerans CFBP13505 P0401 0.74 PagCFBP13505_RS19890 D-alanyl-D-alanine- carboxypeptidase/endopeptidase AmpH 0.85 PagCFBP13505_RS02550 DNA-binding transcriptional regulator KdgR low > 74
Erwinia tracheiphila SCR3 0.69 LU632_RS21660 ampH D-alanyl-D-alanine- carboxypeptidase/endopeptidase AmpH 0.80 LU632_RS13230 kdgR DNA-binding transcriptional regulator KdgR low > 74
Erwinia tracheiphila HP pepo 2.2 0.69 IJEDHG_13340 ampH D-alanyl-D-alanine-carboxypeptidase/endopeptidase AmpH 0.80 IJEDHG_22355 kdgR DNA-binding transcriptional regulator KdgR low > 61
Erwinia amylovora T8 0.67 OLJFJH_07570 D-alanyl-D-alanine-carboxypeptidase/endopeptidase AmpH 0.12 OLJFJH_18260 IclR family transcriptional regulator low > 58
Serratia liquefaciens MT49 0.61 IAI46_02780 D-alanyl-D-alanine- carboxypeptidase/endopeptidase AmpH 0.80 IAI46_10820 DNA-binding transcriptional regulator KdgR low > 86
Rahnella sp. WP5 0.60 EX31_RS04370 D-alanyl-D-alanine- carboxypeptidase/endopeptidase AmpH 0.84 EX31_RS24895 DNA-binding transcriptional regulator KdgR low > 89
Pseudomonas fluorescens FW300-N2E2 0.10 Pf6N2E2_2130 Beta-lactamase (EC 3.5.2.6) 0.25 Pf6N2E2_2839 Pca regulon regulatory protein PcaR low > 103
Pseudomonas fluorescens FW300-N2C3 0.09 AO356_01295 class C beta-lactamase 0.50 AO356_28560 transcriptional regulator low > 104
Variovorax sp. SCN45 0.09 GFF5954 Beta-lactamase class C-like and penicillin binding proteins (PBPs) superfamily 0.26 GFF3166 Transcriptional regulator, IclR family low > 127
Pseudomonas segetis P6 0.08 MPMX49_01917 Beta-lactamase 0.20 MPMX49_02735 Pca regulon regulatory protein low > 75
Pseudomonas lactucae CFBP13502 0.08 GEMAOFIL_03296 Beta-lactamase 0.25 GEMAOFIL_01498 Pca regulon regulatory protein low > 93
Dickeya dianthicola ME23 0.07 DZA65_RS21670 serine hydrolase 0.89 DZA65_RS11830 DNA-binding transcriptional regulator KdgR low > 75
Pseudomonas fluorescens SBW25-INTG 0.07 PFLU_RS16915 class C beta-lactamase 0.25 PFLU_RS06715 IclR family transcriptional regulator low > 109
Pseudomonas fluorescens SBW25 0.07 PFLU_RS16915 class C beta-lactamase 0.25 PFLU_RS06715 IclR family transcriptional regulator low > 109
Dickeya dianthicola 67-19 0.07 HGI48_RS20655 serine hydrolase 0.89 HGI48_RS11490 DNA-binding transcriptional regulator KdgR low > 71
Acinetobacter baumannii LAC-4 0.07 RR41_RS05565 ADC family extended-spectrum class C beta-lactamase 0.17 RR41_RS08655 IclR family transcriptional regulator low > 55
Pseudomonas fluorescens FW300-N1B4 0.07 Pf1N1B4_73 Beta-lactamase (EC 3.5.2.6) 0.25 Pf1N1B4_3230 Pca regulon regulatory protein PcaR low > 87
Pseudomonas fluorescens GW456-L13 0.07 PfGW456L13_2479 Beta-lactamase (EC 3.5.2.6) 0.25 PfGW456L13_4594 Pca regulon regulatory protein PcaR low > 87

Not shown: 5 genomes with orthologs for GFF4271 only; 34 genomes with orthologs for GFF2842 only