Conservation of cofitness between GFF4764 and GFF2630 in Sphingobium sp. HT1-2

108 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Sphingobium sp. HT1-2 1.0 GFF4764 Threonine synthase (EC 4.2.3.1) 1.0 GFF2630 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) 0.86 5
Sphingomonas koreensis DSMZ 15582 0.79 Ga0059261_1999 threonine synthase 0.77 Ga0059261_4223 3-isopropylmalate dehydratase, large subunit 0.98 5
Azospirillum sp. SherDot2 0.58 MPMX19_00671 Threonine synthase 0.66 MPMX19_01998 3-isopropylmalate dehydratase large subunit
Azospirillum brasilense Sp245 0.57 AZOBR_RS10545 threonine synthase 0.66 AZOBR_RS03545 isopropylmalate isomerase
Magnetospirillum magneticum AMB-1 0.57 AMB_RS17140 threonine synthase 0.65 AMB_RS20560 3-isopropylmalate dehydratase large subunit
Pseudomonas aeruginosa PA14 0.55 IKLFDK_19070 threonine synthase 0.59 IKLFDK_15880 3-isopropylmalate dehydratase large subunit low > 100
Dinoroseobacter shibae DFL-12 0.55 Dshi_1146 threonine synthase (RefSeq) 0.60 Dshi_0085 3-isopropylmalate dehydratase, large subunit (RefSeq)
Rhodospirillum rubrum S1H 0.54 Rru_A3233 Threonine synthase (NCBI) 0.64 Rru_A1189 3-isopropylmalate dehydratase large subunit region (NCBI)
Pseudomonas stutzeri RCH2 0.54 Psest_3125 threonine synthase 0.60 Psest_2591 3-isopropylmalate dehydratase, large subunit
Pseudomonas fluorescens FW300-N2E3 0.54 AO353_04350 threonine synthase 0.61 AO353_20620 isopropylmalate isomerase
Pseudomonas sp. RS175 0.54 PFR28_00334 Threonine synthase 0.60 PFR28_02824 3-isopropylmalate dehydratase large subunit
Pseudomonas fluorescens FW300-N1B4 0.54 Pf1N1B4_3014 Threonine synthase (EC 4.2.3.1) 0.61 Pf1N1B4_15 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)
Pseudomonas sp. S08-1 0.54 OH686_17765 threonine synthase 0.60 OH686_04480 3-isopropylmalate dehydratase large subunit low > 80
Marinobacter adhaerens HP15 0.53 HP15_765 threonine synthase 0.58 HP15_1834 protein containing 3-isopropylmalate dehydratase, large subunit region domain
Pseudomonas segetis P6 0.53 MPMX49_01578 Threonine synthase 0.59 MPMX49_03074 3-isopropylmalate dehydratase large subunit 0.88 6
Pseudomonas sp. BP01 0.53 JOY50_RS11715 thrC threonine synthase 0.60 JOY50_RS16630 leuC 3-isopropylmalate dehydratase large subunit
Pseudomonas fluorescens GW456-L13 0.53 PfGW456L13_1724 Threonine synthase (EC 4.2.3.1) 0.61 PfGW456L13_3948 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)
Pseudomonas putida KT2440 0.53 PP_1471 Threonine synthase 0.60 PP_1985 3-isopropylmalate dehydratase large subunit
Pseudomonas fluorescens FW300-N2E2 0.53 Pf6N2E2_3142 Threonine synthase (EC 4.2.3.1) 0.60 Pf6N2E2_63 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)
Pseudomonas sp. DMC3 0.53 GFF1990 Threonine synthase 0.60 GFF785 3-isopropylmalate dehydratase large subunit
Pseudomonas fluorescens FW300-N2C3 0.53 AO356_06370 threonine synthase 0.61 AO356_21400 isopropylmalate isomerase
Pseudomonas simiae WCS417 0.53 PS417_22880 threonine synthase 0.61 PS417_18600 isopropylmalate isomerase
Pseudomonas lactucae CFBP13502 0.53 GEMAOFIL_04726 Threonine synthase 0.61 GEMAOFIL_03948 3-isopropylmalate dehydratase large subunit low > 93
Pseudomonas sp. SVBP6 0.53 COO64_RS04940 thrC threonine synthase 0.61 COO64_RS05665 leuC 3-isopropylmalate dehydratase large subunit
Pseudomonas syringae pv. syringae B728a ΔmexB 0.52 Psyr_1291 L-threonine synthase 0.60 Psyr_1983 3-isopropylmalate dehydratase, large subunit
Pseudomonas syringae pv. syringae B728a 0.52 Psyr_1291 L-threonine synthase 0.60 Psyr_1983 3-isopropylmalate dehydratase, large subunit
Pseudomonas fluorescens SBW25-INTG 0.52 PFLU_RS24545 threonine synthase 0.61 PFLU_RS20580 3-isopropylmalate dehydratase large subunit
Pseudomonas fluorescens SBW25 0.52 PFLU_RS24545 threonine synthase 0.61 PFLU_RS20580 3-isopropylmalate dehydratase large subunit low > 109
Phaeobacter inhibens DSM 17395 0.52 PGA1_c06310 threonine synthase ThrC 0.61 PGA1_c29780 3-isopropylmalate dehydratase large subunit
Rhizobium sp. OAE497 0.50 ABIE40_RS04230 threonine synthase 0.60 ABIE40_RS18380 3-isopropylmalate dehydratase large subunit
Sinorhizobium meliloti 1021 0.50 SMc00077 threonine synthase 0.63 SMc03823 isopropylmalate isomerase large subunit
Bosea sp. OAE506 0.50 ABIE41_RS22985 threonine synthase 0.65 ABIE41_RS11660 3-isopropylmalate dehydratase large subunit
Xanthobacter sp. DMC5 0.49 GFF1319 Threonine synthase 0.59 GFF1852 3-isopropylmalate dehydratase large subunit
Rhodopseudomonas palustris CGA009 0.49 TX73_004325 threonine synthase 0.62 TX73_001245 3-isopropylmalate dehydratase large subunit
Agrobacterium fabrum C58 0.49 Atu0787 threonine synthase 0.62 Atu2709 3-isopropylmalate dehydratase, large subunit
Caulobacter crescentus NA1000 0.48 CCNA_03510 threonine synthase 0.60 CCNA_00196 3-isopropylmalate dehydratase large subunit
Caulobacter crescentus NA1000 Δfur 0.48 CCNA_03510 threonine synthase 0.60 CCNA_00196 3-isopropylmalate dehydratase large subunit
Acidovorax sp. GW101-3H11 0.36 Ac3H11_1505 Threonine synthase (EC 4.2.3.1) 0.58 Ac3H11_1525 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)
Variovorax sp. SCN45 0.36 GFF2800 Threonine synthase (EC 4.2.3.1) 0.58 GFF3890 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)
Ralstonia sp. UNC404CL21Col 0.35 ABZR87_RS11450 threonine synthase 0.58 ABZR87_RS14540 3-isopropylmalate dehydratase large subunit
Brevundimonas sp. GW460-12-10-14-LB2 0.35 A4249_RS00020 threonine synthase 0.48 A4249_RS10005 3-isopropylmalate dehydratase large subunit 0.99 9
Methylophilus sp. DMC18 0.35 GFF1164 Threonine synthase 0.61 GFF646 3-isopropylmalate dehydratase large subunit
Dechlorosoma suillum PS 0.35 Dsui_2904 threonine synthase 0.57 Dsui_3201 3-isopropylmalate dehydratase, large subunit
Variovorax sp. OAS795 0.35 ABID97_RS10895 threonine synthase 0.59 ABID97_RS08465 3-isopropylmalate dehydratase large subunit
Ralstonia solanacearum GMI1000 0.35 RS_RS06660 threonine synthase 0.58 RS_RS10000 3-isopropylmalate dehydratase large subunit
Ralstonia solanacearum UW163 0.35 UW163_RS13325 threonine synthase 0.58 UW163_RS11105 3-isopropylmalate dehydratase large subunit
Ralstonia solanacearum IBSBF1503 0.35 RALBFv3_RS15880 threonine synthase 0.58 RALBFv3_RS02620 3-isopropylmalate dehydratase large subunit
Ralstonia solanacearum PSI07 0.34 RPSI07_RS17485 threonine synthase 0.58 RPSI07_RS14695 3-isopropylmalate dehydratase large subunit
Cupriavidus basilensis FW507-4G11 0.34 RR42_RS12535 threonine synthase 0.58 RR42_RS14400 isopropylmalate isomerase
Paraburkholderia sabiae LMG 24235 0.34 QEN71_RS22400 threonine synthase 0.57 QEN71_RS17605 3-isopropylmalate dehydratase large subunit 0.74 48
Paraburkholderia graminis OAS925 0.34 ABIE53_002027 threonine synthase 0.58 ABIE53_004801 3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit
Burkholderia phytofirmans PsJN 0.34 BPHYT_RS08960 threonine synthase 0.57 BPHYT_RS33915 isopropylmalate isomerase 0.63 58
Herbaspirillum seropedicae SmR1 0.34 HSERO_RS10470 threonine synthase 0.58 HSERO_RS16515 isopropylmalate isomerase
Paraburkholderia bryophila 376MFSha3.1 0.34 H281DRAFT_00811 L-threonine synthase 0.58 H281DRAFT_06075 3-isopropylmalate dehydratase, large subunit
Castellaniella sp019104865 MT123 0.33 ABCV34_RS02300 threonine synthase 0.60 ABCV34_RS04290 3-isopropylmalate dehydratase large subunit
Hydrogenophaga sp. GW460-11-11-14-LB1 0.33 GFF3936 Threonine synthase (EC 4.2.3.1) 0.58 GFF3363 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)
Phocaeicola dorei CL03T12C01 0.27 ABI39_RS10440 threonine synthase 0.51 ABI39_RS10200 3-isopropylmalate dehydratase large subunit 0.88 4
Phocaeicola vulgatus CL09T03C04 0.27 HMPREF1058_RS14730 threonine synthase 0.50 HMPREF1058_RS14550 3-isopropylmalate dehydratase large subunit 0.81 30
Bifidobacterium breve UCC2003 0.26 BBR_RS14070 threonine synthase (EC 4.2.3.1) (from data) 0.53 BBR_RS19630 3-isopropylmalate dehydratase large subunit low > 34
Parabacteroides merdae CL09T00C40 0.26 HMPREF1078_RS10395 threonine synthase 0.50 HMPREF1078_RS16660 3-isopropylmalate dehydratase large subunit 0.92 23
Bacteroides stercoris CC31F 0.26 HMPREF1181_RS00050 threonine synthase 0.50 HMPREF1181_RS14145 3-isopropylmalate dehydratase large subunit 0.92 28
Bacteroides thetaiotaomicron VPI-5482 0.26 BT2401 threonine synthase (NCBI ptt file) 0.50 BT1860 3-isopropylmalate dehydratase large subunit (NCBI ptt file) 0.90 29
Bacteroides ovatus ATCC 8483 0.26 BACOVA_03023 threonine synthase 0.50 BACOVA_04603 3-isopropylmalate dehydratase, large subunit 0.94 20
Echinicola vietnamensis KMM 6221, DSM 17526 0.25 Echvi_2002 threonine synthase 0.48 Echvi_2059 3-isopropylmalate dehydratase, large subunit 0.73 48
Alteromonas macleodii MIT1002 0.25 MIT1002_03084 Threonine synthase 0.57 MIT1002_00947 3-isopropylmalate dehydratase large subunit 0.92 34
Shewanella sp. ANA-3 0.25 Shewana3_1141 threonine synthase (RefSeq) 0.57 Shewana3_3759 isopropylmalate isomerase large subunit (RefSeq) 0.93 19
Cellulophaga baltica 18 0.25 M666_RS11605 threonine synthase 0.51 M666_RS15060 3-isopropylmalate dehydratase large subunit low > 67
Shewanella oneidensis MR-1 0.24 SO3413 thrC threonine synthase (NCBI ptt file) 0.56 SO4234 leuC 3-isopropylmalate dehydratase, large subunit (NCBI ptt file) 0.97 11
Pantoea agglomerans CFBP13505 P0401 0.24 PagCFBP13505_RS21900 threonine synthase 0.57 PagCFBP13505_RS12990 3-isopropylmalate dehydratase large subunit low > 74
Enterobacter asburiae PDN3 0.24 EX28DRAFT_3616 threonine synthase 0.57 EX28DRAFT_3668 3-isopropylmalate dehydratase, large subunit 0.51 32
Enterobacter sp. TBS_079 0.24 MPMX20_00712 Threonine synthase 0.57 MPMX20_00767 3-isopropylmalate dehydratase large subunit 1 0.91 20
Dickeya dadantii 3937 0.24 DDA3937_RS18405 threonine synthase 0.59 DDA3937_RS18125 3-isopropylmalate dehydratase large subunit 0.67 72
Dickeya dianthicola 67-19 0.24 HGI48_RS18335 threonine synthase 0.58 HGI48_RS18065 3-isopropylmalate dehydratase large subunit 0.81 1
Dickeya dianthicola ME23 0.24 DZA65_RS19475 threonine synthase 0.58 DZA65_RS19210 3-isopropylmalate dehydratase large subunit 0.71 8
Erwinia amylovora T8 0.24 OLJFJH_01485 threonine synthase 0.55 OLJFJH_01295 3-isopropylmalate dehydratase large subunit 0.93 7
Klebsiella pneumoniae MKP103 0.24 KDGMDA_12520 threonine synthase 0.58 KDGMDA_12900 3-isopropylmalate dehydratase large subunit 1 low > 95
Lysobacter sp. OAE881 0.24 ABIE51_RS17530 threonine synthase 0.48 ABIE51_RS17575 3-isopropylmalate dehydratase large subunit 0.92 47
Serratia liquefaciens MT49 0.24 IAI46_03040 threonine synthase 0.56 IAI46_03345 3-isopropylmalate dehydratase large subunit 0.76 34
Pantoea sp. MT58 0.24 IAI47_16205 threonine synthase 0.57 IAI47_16010 3-isopropylmalate dehydratase large subunit 0.94 8
Mucilaginibacter yixingensis YX-36 DSM 26809 0.24 ABZR88_RS18960 threonine synthase 0.51 ABZR88_RS11595 3-isopropylmalate dehydratase large subunit
Shewanella loihica PV-4 0.24 Shew_1081 threonine synthase (RefSeq) 0.56 Shew_3470 isopropylmalate isomerase large subunit (RefSeq) 0.98 11
Pedobacter sp. GW460-11-11-14-LB5 0.23 CA265_RS23465 threonine synthase 0.51 CA265_RS15830 3-isopropylmalate dehydratase large subunit 0.88 5
Rahnella sp. WP5 0.23 EX31_RS03935 threonine synthase 0.58 EX31_RS03690 3-isopropylmalate dehydratase large subunit 0.99 3
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.23 GFF1080 Threonine synthase (EC 4.2.3.1) 0.57 GFF166 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) low > 78
Erwinia tracheiphila HP pepo 2.2 0.23 IJEDHG_06290 thrC threonine synthase 0.53 IJEDHG_06005 leuC 3-isopropylmalate dehydratase large subunit
Erwinia tracheiphila SCR3 0.23 LU632_RS02620 thrC threonine synthase 0.53 LU632_RS02870 leuC 3-isopropylmalate dehydratase large subunit
Klebsiella michiganensis M5al 0.23 BWI76_RS04255 threonine synthase 0.57 BWI76_RS04670 3-isopropylmalate dehydratase large subunit 0.93 12
Escherichia coli ECRC99 0.23 KEDOAH_17055 thrC threonine synthase 0.57 KEDOAH_17430 leuC1 3-isopropylmalate dehydratase large subunit 1
Escherichia coli BL21 0.23 ECD_00004 L-threonine synthase 0.57 ECD_00074 3-isopropylmalate dehydratase large subunit 0.95 10
Escherichia coli ECRC62 0.23 BNILDI_08170 thrC threonine synthase 0.57 BNILDI_08540 leuC1 3-isopropylmalate dehydratase large subunit 1 0.92 13
Escherichia coli Nissle 1917 0.23 ECOLIN_RS00020 threonine synthase 0.57 ECOLIN_RS00390 3-isopropylmalate dehydratase large subunit low > 55
Escherichia fergusonii Becca 0.23 EFB2_04039 Threonine synthase 0.58 EFB2_03973 3-isopropylmalate dehydratase large subunit low > 86
Escherichia coli BW25113 0.23 b0004 thrC threonine synthase (NCBI) 0.57 b0072 leuC isopropylmalate isomerase large subunit (NCBI) 0.89 32
Escherichia coli ECRC101 0.23 MCAODC_01615 thrC threonine synthase 0.57 MCAODC_01240 leuC1 3-isopropylmalate dehydratase large subunit 1 0.78 36
Escherichia coli ECRC102 0.23 NIAGMN_08950 thrC threonine synthase 0.57 NIAGMN_08575 leuC1 3-isopropylmalate dehydratase large subunit 1 0.96 39
Escherichia coli ECRC100 0.23 OKFHMN_11100 thrC threonine synthase 0.57 OKFHMN_10725 leuC1 3-isopropylmalate dehydratase large subunit 1 0.98 29
Escherichia coli ECRC98 0.23 JDDGAC_14695 thrC threonine synthase 0.57 JDDGAC_14320 leuC1 3-isopropylmalate dehydratase large subunit 1 0.85 21
Escherichia coli ECOR27 0.23 NOLOHH_03430 thrC threonine synthase 0.57 NOLOHH_03070 leuC1 3-isopropylmalate dehydratase large subunit 1 0.98 1
Escherichia coli HS(pFamp)R (ATCC 700891) 0.23 OHPLBJKB_03656 Threonine synthase 0.57 OHPLBJKB_03585 3-isopropylmalate dehydratase large subunit low > 74
Shewanella amazonensis SB2B 0.23 Sama_0907 threonine synthase (RefSeq) 0.55 Sama_0337 isopropylmalate isomerase large subunit (RefSeq) 0.94 15
Escherichia coli ECOR38 0.23 HEPCGN_09105 thrC threonine synthase 0.57 HEPCGN_08705 leuC1 3-isopropylmalate dehydratase large subunit 1 0.90 21
Vibrio cholerae E7946 ATCC 55056 0.23 CSW01_11965 threonine synthase 0.54 CSW01_12605 3-isopropylmalate dehydratase large subunit low > 62
Pectobacterium carotovorum WPP14 0.23 HER17_RS02805 threonine synthase 0.58 HER17_RS03075 3-isopropylmalate dehydratase large subunit 0.95 5
Xanthomonas campestris pv. campestris strain 8004 0.22 Xcc-8004.2954.1 Threonine synthase (EC 4.2.3.1) 0.61 Xcc-8004.1049.1 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) 0.79 29
Rhodanobacter sp. FW510-T8 0.22 OKGIIK_13570 thrC threonine synthase 0.47 OKGIIK_13585 leuC 3-isopropylmalate dehydratase large subunit low > 53
Dyella japonica UNC79MFTsu3.2 0.22 ABZR86_RS15975 threonine synthase (EC 4.2.3.1) (from data) 0.48 ABZR86_RS15960 3-isopropylmalate dehydratase large subunit 0.96 21
Rhodanobacter sp000427505 FW510-R12 0.22 LRK53_RS03155 threonine synthase 0.50 LRK53_RS16375 3-isopropylmalate dehydratase large subunit low > 59
Rhodanobacter denitrificans FW104-10B01 0.21 LRK54_RS10355 threonine synthase 0.55 LRK54_RS07375 3-isopropylmalate dehydratase large subunit low > 59
Rhodanobacter denitrificans MT42 0.20 LRK55_RS09995 threonine synthase 0.55 LRK55_RS07105 3-isopropylmalate dehydratase large subunit low > 63

Not shown: 0 genomes with orthologs for GFF4764 only; 11 genomes with orthologs for GFF2630 only