| Organism | Ratio1 | Gene1 | Name1 | Description1 | Ratio2 | Gene2 | Name2 | Description2 | Cofit | Rank |
| Sphingobium sp. HT1-2 | 1.0 | GFF216 | | 5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13), N-terminal domain | 1.0 | GFF2370 | | Anthranilate synthase, aminase component (EC 4.1.3.27) | 0.85 | 7 |
| Sphingomonas koreensis DSMZ 15582 | 0.63 | Ga0059261_0991 | | Methionine synthase I (cobalamin-dependent), methyltransferase domain | 0.72 | Ga0059261_0256 | | anthranilate synthase component I, non-proteobacterial lineages | 0.68 | 48 |
| Brevundimonas sp. GW460-12-10-14-LB2 | 0.52 | A4249_RS07930 | | homocysteine S-methyltransferase family protein | 0.42 | A4249_RS06155 | | anthranilate synthase component I | low | > 48 |
| Caulobacter crescentus NA1000 | 0.52 | CCNA_02222 | | 5-methyltetrahydrofolate--homocysteine methyltransferase homocysteine-binding subunit | 0.45 | CCNA_01972 | | anthranilate synthase component I | low | > 66 |
| Caulobacter crescentus NA1000 Δfur | 0.52 | CCNA_02222 | | 5-methyltetrahydrofolate--homocysteine methyltransferase homocysteine-binding subunit | 0.45 | CCNA_01972 | | anthranilate synthase component I | low | > 67 |
| Lysobacter sp. OAE881 | 0.52 | ABIE51_RS09090 | | homocysteine S-methyltransferase family protein | 0.36 | ABIE51_RS04150 | | anthranilate synthase component I | 0.84 | 56 |
| Paraburkholderia sabiae LMG 24235 | 0.52 | QEN71_RS01195 | | homocysteine S-methyltransferase family protein | 0.34 | QEN71_RS27550 | | anthranilate synthase component I | low | > 153 |
| Paraburkholderia bryophila 376MFSha3.1 | 0.51 | H281DRAFT_02075 | | methionine synthase (B12-dependent) | 0.34 | H281DRAFT_05715 | | anthranilate synthase, component I | — | — |
| Burkholderia phytofirmans PsJN | 0.51 | BPHYT_RS02310 | | 5-methyltetrahydrofolate--homocysteine methyltransferase | 0.34 | BPHYT_RS17390 | | anthranilate synthase subunit I | 0.62 | 25 |
| Paraburkholderia graminis OAS925 | 0.51 | ABIE53_000604 | | 5-methyltetrahydrofolate--homocysteine methyltransferase | 0.34 | ABIE53_003640 | | anthranilate synthase component 1 | — | — |
| Ralstonia solanacearum GMI1000 | 0.50 | RS_RS01450 | | 5-methyltetrahydrofolate--homocysteine methyltransferase | 0.35 | RS_RS14430 | | anthranilate synthase component I | low | > 80 |
| Hydrogenophaga sp. GW460-11-11-14-LB1 | 0.50 | GFF1952 | | 5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13) | 0.35 | GFF3106 | | Anthranilate synthase, aminase component (EC 4.1.3.27) | — | — |
| Ralstonia sp. UNC404CL21Col | 0.50 | ABZR87_RS06420 | | homocysteine S-methyltransferase family protein | 0.35 | ABZR87_RS02140 | | anthranilate synthase component I | low | > 80 |
| Rhodanobacter denitrificans MT42 | 0.50 | LRK55_RS01890 | | homocysteine S-methyltransferase family protein | 0.37 | LRK55_RS11145 | | anthranilate synthase component I | low | > 63 |
| Xanthomonas campestris pv. campestris strain 8004 | 0.50 | Xcc-8004.3380.1 | | 5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13) | 0.36 | Xcc-8004.608.1 | | Anthranilate synthase, aminase component (EC 4.1.3.27) | low | > 74 |
| Rhodanobacter denitrificans FW104-10B01 | 0.50 | LRK54_RS02115 | | homocysteine S-methyltransferase family protein | 0.37 | LRK54_RS11415 | | anthranilate synthase component I | low | > 59 |
| Acidovorax sp. GW101-3H11 | 0.50 | Ac3H11_3297 | | 5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13) | 0.35 | Ac3H11_767 | | Anthranilate synthase, aminase component (EC 4.1.3.27) | low | > 79 |
| Variovorax sp. OAS795 | 0.50 | ABID97_RS03450 | | homocysteine S-methyltransferase family protein | 0.34 | ABID97_RS05250 | | anthranilate synthase component I | 0.38 | 77 |
| Ralstonia solanacearum PSI07 | 0.50 | RPSI07_RS22705 | | 5-methyltetrahydrofolate--homocysteine methyltransferase | 0.35 | RPSI07_RS10755 | | anthranilate synthase component I | — | — |
| Cupriavidus basilensis FW507-4G11 | 0.50 | RR42_RS00770 | | 5-methyltetrahydrofolate--homocysteine methyltransferase | 0.35 | RR42_RS18295 | | anthranilate synthase component I | low | > 128 |
| Ralstonia solanacearum IBSBF1503 | 0.49 | RALBFv3_RS10615 | | 5-methyltetrahydrofolate--homocysteine methyltransferase | 0.34 | RALBFv3_RS06485 | | anthranilate synthase component I | low | > 76 |
| Variovorax sp. SCN45 | 0.49 | GFF6399 | | 5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13), N-terminal domain | 0.34 | GFF5896 | | Anthranilate synthase, aminase component (EC 4.1.3.27) | low | > 127 |
| Ralstonia solanacearum UW163 | 0.49 | UW163_RS02965 | | 5-methyltetrahydrofolate--homocysteine methyltransferase | 0.34 | UW163_RS07140 | | anthranilate synthase component I | — | — |
| Cellulophaga baltica 18 | 0.48 | M666_RS08200 | | homocysteine S-methyltransferase family protein | 0.23 | M666_RS09090 | | anthranilate synthase component I family protein | low | > 67 |
| Rhodanobacter sp000427505 FW510-R12 | 0.48 | LRK53_RS07920 | | homocysteine S-methyltransferase family protein | 0.36 | LRK53_RS17085 | | anthranilate synthase component I | 0.79 | 5 |
| Dyella japonica UNC79MFTsu3.2 | 0.48 | ABZR86_RS07585 | | homocysteine S-methyltransferase family protein | 0.37 | ABZR86_RS12180 | | anthranilate synthase component I | 0.91 | 49 |
| Rhodanobacter sp. FW510-T8 | 0.48 | OKGIIK_09185 | metH1 | 5-methyltetrahydrofolate--homocysteine methyltransferase | 0.36 | OKGIIK_12405 | trpE | anthranilate synthase component I | low | > 53 |
| Echinicola vietnamensis KMM 6221, DSM 17526 | 0.47 | Echvi_3639 | | Methionine synthase I (cobalamin-dependent), methyltransferase domain | 0.24 | Echvi_2504 | | Anthranilate/para-aminobenzoate synthases component I | 0.56 | 69 |
| Phaeobacter inhibens DSM 17395 | 0.14 | PGA1_c13370 | | Methionine synthase component, methyltransferase domain (EC:2.1.1.13) (from data) | 0.44 | PGA1_c16860 | | anthranilate synthase component 1 | — | — |
| Dinoroseobacter shibae DFL-12 | 0.13 | Dshi_1074 | | homocysteine S-methyltransferase (RefSeq) | 0.45 | Dshi_1796 | | anthranilate synthase component I (RefSeq) | — | — |
Not shown: 1 genomes with orthologs for GFF216 only; 50 genomes with orthologs for GFF2370 only