| Organism | Ratio1 | Gene1 | Name1 | Description1 | Ratio2 | Gene2 | Name2 | Description2 | Cofit | Rank |
| Sphingobium sp. HT1-2 | 1.0 | GFF4076 | | Two-component transcriptional response regulator, LuxR family | 1.0 | GFF1484 | | Free methionine-(R)-sulfoxide reductase, contains GAF domain | low | > 95 |
| Sphingomonas koreensis DSMZ 15582 | 0.90 | Ga0059261_1369 | | Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain | 0.64 | Ga0059261_3708 | | GAF domain-containing protein | low | > 68 |
| Rhizobium sp. OAE497 | 0.71 | ABIE40_RS05660 | | response regulator transcription factor | 0.61 | ABIE40_RS12595 | | GAF domain-containing protein | low | > 107 |
| Brevundimonas sp. GW460-12-10-14-LB2 | 0.63 | A4249_RS15665 | | response regulator transcription factor | 0.44 | A4249_RS01025 | | GAF domain-containing protein | low | > 48 |
| Castellaniella sp019104865 MT123 | 0.62 | ABCV34_RS15610 | | response regulator transcription factor | 0.58 | ABCV34_RS14700 | | GAF domain-containing protein | low | > 48 |
| Caulobacter crescentus NA1000 Δfur | 0.61 | CCNA_02854 | | two-component response regulator | 0.46 | CCNA_02362 | | GAF domain-containing protein | low | > 67 |
| Caulobacter crescentus NA1000 | 0.61 | CCNA_02854 | | two-component response regulator | 0.46 | CCNA_02362 | | GAF domain-containing protein | low | > 66 |
| Shewanella amazonensis SB2B | 0.55 | Sama_3303 | | response regulator receiver protein (RefSeq) | 0.55 | Sama_1583 | | GAF domain-containing protein (RefSeq) | low | > 62 |
| Shewanella oneidensis MR-1 | 0.54 | SO4647 | | DNA-binding response regulator (NCBI ptt file) | 0.52 | SO2603 | | conserved hypothetical protein (NCBI ptt file) | low | > 76 |
| Shewanella loihica PV-4 | 0.53 | Shew_2695 | | two component transcriptional regulator (RefSeq) | 0.55 | Shew_1800 | | putative GAF sensor protein (RefSeq) | low | > 60 |
| Shewanella sp. ANA-3 | 0.53 | Shewana3_4025 | | two component transcriptional regulator (RefSeq) | 0.54 | Shewana3_1776 | | putative GAF sensor protein (RefSeq) | low | > 73 |
| Rhodanobacter sp000427505 FW510-R12 | 0.52 | LRK53_RS17390 | | response regulator transcription factor | 0.55 | LRK53_RS01185 | | GAF domain-containing protein | — | — |
| Alteromonas macleodii MIT1002 | 0.51 | MIT1002_01421 | | Transcriptional regulatory protein PhoP | 0.54 | MIT1002_02022 | | Free methionine-R-sulfoxide reductase | low | > 70 |
| Rhodanobacter denitrificans MT42 | 0.51 | LRK55_RS05740 | | response regulator transcription factor | 0.54 | LRK55_RS06935 | | GAF domain-containing protein | — | — |
| Rhodanobacter denitrificans FW104-10B01 | 0.51 | LRK54_RS05985 | | response regulator transcription factor | 0.54 | LRK54_RS07200 | | GAF domain-containing protein | low | > 59 |
| Xanthomonas campestris pv. campestris strain 8004 | 0.51 | Xcc-8004.5008.1 | | Two-component system regulatory protein | 0.49 | Xcc-8004.4532.1 | | Free methionine-(R)-sulfoxide reductase, contains GAF domain | — | — |
| Lysobacter sp. OAE881 | 0.51 | ABIE51_RS03940 | | response regulator transcription factor | 0.54 | ABIE51_RS17995 | | GAF domain-containing protein | low | > 62 |
| Rhodanobacter sp. FW510-T8 | 0.50 | OKGIIK_00635 | ompR | DNA-binding response regulator | 0.55 | OKGIIK_16450 | msrC | diguanylate cyclase | — | — |
| Dyella japonica UNC79MFTsu3.2 | 0.50 | ABZR86_RS18360 | | response regulator transcription factor | 0.58 | ABZR86_RS12705 | | GAF domain-containing protein | low | > 74 |
| Kangiella aquimarina DSM 16071 | 0.50 | B158DRAFT_1560 | | Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain | 0.52 | B158DRAFT_1416 | | GAF domain-containing protein | low | > 40 |
| Pseudomonas segetis P6 | 0.50 | MPMX49_02578 | | Transcriptional regulatory protein QseB | 0.55 | MPMX49_02276 | | Free methionine-R-sulfoxide reductase | low | > 75 |
| Pseudomonas aeruginosa PA14 | 0.48 | IKLFDK_13340 | | two-component system response regulator CarR | 0.53 | IKLFDK_14335 | | GAF domain-containing protein | low | > 100 |
| Pseudomonas sp. SVBP6 | 0.47 | COO64_RS17260 | | response regulator transcription factor | 0.56 | COO64_RS05955 | | GAF domain-containing protein | low | > 93 |
| Pseudomonas sp. DMC3 | 0.47 | GFF1365 | | Transcriptional regulatory protein QseB | 0.56 | GFF4590 | | Free methionine-R-sulfoxide reductase | low | > 89 |
| Pseudomonas fluorescens FW300-N2E3 | 0.47 | AO353_19775 | | transcriptional regulator | 0.53 | AO353_19180 | | GAF domain-containing protein | low | > 101 |
| Pseudomonas fluorescens GW456-L13 | 0.47 | PfGW456L13_2451 | | Two-component system response regulator QseB | 0.56 | PfGW456L13_2258 | | Free methionine-(R)-sulfoxide reductase, contains GAF domain | low | > 87 |
| Pseudomonas sp. S08-1 | 0.46 | OH686_00055 | | Two-component system response regulator QseB | 0.56 | OH686_22605 | | Free methionine-(R)-sulfoxide reductase, contains GAF domain | low | > 80 |
| Pseudomonas fluorescens SBW25 | 0.46 | PFLU_RS10435 | | response regulator transcription factor | 0.56 | PFLU_RS08545 | | GAF domain-containing protein | low | > 109 |
| Pseudomonas fluorescens SBW25-INTG | 0.46 | PFLU_RS10435 | | response regulator transcription factor | 0.56 | PFLU_RS08545 | | GAF domain-containing protein | low | > 109 |
| Pseudomonas putida KT2440 | 0.46 | PP_2347 | | DNA-binding response regulator | 0.55 | PP_1877 | | free methionine-(R)-sulfoxide reductase | low | > 96 |
| Pseudomonas lactucae CFBP13502 | 0.46 | GEMAOFIL_02165 | | Transcriptional regulatory protein QseB | 0.55 | GEMAOFIL_01850 | | Free methionine-R-sulfoxide reductase | low | > 93 |
| Pseudomonas sp. BP01 | 0.46 | JOY50_RS10885 | | response regulator transcription factor | 0.56 | JOY50_RS16960 | | GAF domain-containing protein | low | > 84 |
| Pseudomonas sp. RS175 | 0.46 | PFR28_02847 | | Transcriptional regulatory protein QseB | 0.54 | PFR28_00990 | | Free methionine-R-sulfoxide reductase | low | > 88 |
| Pseudomonas simiae WCS417 | 0.46 | PS417_10270 | | transcriptional regulator | 0.56 | PS417_08590 | | hypothetical protein | low | > 88 |
| Pseudomonas fluorescens FW300-N1B4 | 0.46 | Pf1N1B4_105 | | Two-component system response regulator QseB | 0.56 | Pf1N1B4_255 | | Free methionine-(R)-sulfoxide reductase, contains GAF domain | — | — |
| Pseudomonas syringae pv. syringae B728a | 0.46 | Psyr_3212 | | Response regulator receiver:Transcriptional regulatory protein, C-terminal | 0.55 | Psyr_3610 | | GAF | low | > 86 |
| Pseudomonas syringae pv. syringae B728a ΔmexB | 0.46 | Psyr_3212 | | Response regulator receiver:Transcriptional regulatory protein, C-terminal | 0.55 | Psyr_3610 | | GAF | — | — |
| Pseudomonas fluorescens FW300-N2E2 | 0.46 | Pf6N2E2_41 | | Two-component system response regulator QseB | 0.56 | Pf6N2E2_2440 | | Free methionine-(R)-sulfoxide reductase, contains GAF domain | low | > 103 |
| Pseudomonas fluorescens FW300-N2C3 | 0.46 | AO356_21280 | | transcriptional regulator | 0.56 | AO356_03060 | | GAF domain-containing protein | low | > 104 |
| Enterobacter asburiae PDN3 | 0.44 | EX28DRAFT_3057 | | Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain | 0.53 | EX28DRAFT_0724 | | GAF domain-containing protein | low | > 76 |
| Erwinia amylovora T8 | 0.44 | OLJFJH_07175 | | two-component system response regulator PmrA | 0.50 | OLJFJH_13000 | | Free methionine-R-sulfoxide reductase | low | > 58 |
| Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | 0.44 | GFF3138 | | Two-component system response regulator QseB | 0.48 | GFF2847 | | Free methionine-(R)-sulfoxide reductase, contains GAF domain | low | > 78 |
| Rahnella sp. WP5 | 0.43 | EX31_RS08605 | | two-component system response regulator PmrA | 0.50 | EX31_RS24870 | | GAF domain-containing protein | low | > 89 |
| Klebsiella michiganensis M5al | 0.43 | BWI76_RS24335 | | two-component system response regulator QseB | 0.50 | BWI76_RS17985 | | hypothetical protein | low | > 92 |
| Escherichia coli BW25113 | 0.42 | b3025 | qseB | DNA-binding response regulator in two-component regulatory system with QseC (NCBI) | 0.53 | b1832 | yebR | free methionine-(R)-sulfoxide reductase (RefSeq) | low | > 76 |
| Enterobacter sp. TBS_079 | 0.42 | MPMX20_03863 | | Transcriptional regulatory protein QseB | 0.53 | MPMX20_02739 | | Free methionine-R-sulfoxide reductase | low | > 85 |
| Erwinia tracheiphila HP pepo 2.2 | 0.42 | IJEDHG_13855 | pmrA | two-component system response regulator PmrA | 0.48 | IJEDHG_22315 | | Free methionine-R-sulfoxide reductase | low | > 61 |
| Erwinia tracheiphila SCR3 | 0.42 | LU632_RS21175 | pmrA | two-component system response regulator PmrA | 0.48 | LU632_RS13260 | | GAF domain-containing protein | low | > 74 |
| Pectobacterium carotovorum WPP14 | 0.42 | HER17_RS11640 | | two-component system response regulator PhoP | 0.49 | HER17_RS11700 | | GAF domain-containing protein | low | > 75 |
| Klebsiella pneumoniae MKP103 | 0.41 | KDGMDA_05180 | | two-component system response regulator QseB | 0.50 | KDGMDA_25255 | | Free methionine-R-sulfoxide reductase | 0.18 | 79 |
| Serratia liquefaciens MT49 | 0.41 | IAI46_10395 | | two-component system response regulator PhoP | 0.50 | IAI46_10790 | | GAF domain-containing protein | low | > 86 |
| Echinicola vietnamensis KMM 6221, DSM 17526 | 0.40 | Echvi_4209 | | Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain | 0.41 | Echvi_0965 | | GAF domain-containing protein | low | > 79 |
| Phocaeicola vulgatus CL09T03C04 | 0.31 | HMPREF1058_RS07665 | | response regulator transcription factor | 0.38 | HMPREF1058_RS05760 | | GAF domain-containing protein | — | — |
Not shown: 32 genomes with orthologs for GFF4076 only; 19 genomes with orthologs for GFF1484 only