| Organism | Ratio1 | Gene1 | Name1 | Description1 | Ratio2 | Gene2 | Name2 | Description2 | Cofit | Rank |
| Vibrio cholerae E7946 ATCC 55056 | 1.0 | CSW01_00430 | | NAD(P)/FAD-dependent oxidoreductase | 1.0 | CSW01_17160 | | TetR/AcrR family transcriptional regulator | 0.52 | 8 |
| Shewanella sp. ANA-3 | 0.62 | Shewana3_0055 | | hypothetical protein (RefSeq) | 0.42 | Shewana3_2864 | | TetR family transcriptional regulator (RefSeq) | low | > 73 |
| Shewanella loihica PV-4 | 0.61 | Shew_3802 | | hypothetical protein (RefSeq) | 0.43 | Shew_2729 | | TetR family transcriptional regulator (RefSeq) | — | — |
| Pantoea agglomerans CFBP13505 P0401 | 0.61 | PagCFBP13505_RS17875 | | NAD(P)/FAD-dependent oxidoreductase | 0.20 | PagCFBP13505_RS08185 | | TetR/AcrR family transcriptional regulator | low | > 74 |
| Shewanella oneidensis MR-1 | 0.61 | SO0054 | | conserved hypothetical protein TIGR00275 (NCBI ptt file) | 0.39 | SO1578 | | transcriptional regulator, TetR family (NCBI ptt file) | low | > 76 |
| Pantoea sp. MT58 | 0.60 | IAI47_01370 | | NAD(P)/FAD-dependent oxidoreductase | 0.18 | IAI47_19875 | | TetR/AcrR family transcriptional regulator | low | > 76 |
| Shewanella amazonensis SB2B | 0.60 | Sama_0064 | | hypothetical protein (RefSeq) | 0.37 | Sama_1089 | | TetR family transcriptional regulator (RefSeq) | low | > 62 |
| Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | 0.59 | GFF523 | | NAD(FAD)-utilizing dehydrogenases | 0.18 | GFF3394 | | putative transcriptional repressor | low | > 78 |
| Rahnella sp. WP5 | 0.59 | EX31_RS05140 | | NAD(P)/FAD-dependent oxidoreductase | 0.19 | EX31_RS01130 | | TetR/AcrR family transcriptional regulator | low | > 89 |
| Dickeya dianthicola ME23 | 0.59 | DZA65_RS22010 | | NAD(P)/FAD-dependent oxidoreductase | 0.12 | DZA65_RS08485 | | TetR/AcrR family transcriptional regulator | low | > 75 |
| Escherichia coli ECOR38 | 0.58 | HEPCGN_15360 | yhiN | Uncharacterized protein YhiN | 0.17 | HEPCGN_24000 | comR | TetR family copper-responsive transcriptional repressor ComR | low | > 88 |
| Enterobacter sp. TBS_079 | 0.58 | MPMX20_04392 | | hypothetical protein | 0.19 | MPMX20_02130 | | HTH-type transcriptional repressor ComR | low | > 85 |
| Escherichia coli BL21 | 0.58 | ECD_03341 | | putative oxidoreductase | 0.17 | ECD_01107 | | repressor for bhsA(ycfR) | low | > 61 |
| Escherichia coli Nissle 1917 | 0.58 | ECOLIN_RS19955 | | NAD(P)/FAD-dependent oxidoreductase | 0.17 | ECOLIN_RS06410 | | TetR family copper-responsive transcriptional repressor ComR | — | — |
| Enterobacter asburiae PDN3 | 0.58 | EX28DRAFT_4070 | | flavoprotein, HI0933 family | 0.18 | EX28DRAFT_1819 | | transcriptional regulator, TetR family | low | > 76 |
| Escherichia fergusonii Becca | 0.58 | EFB2_00323 | | hypothetical protein | 0.17 | EFB2_02864 | | HTH-type transcriptional repressor ComR | low | > 86 |
| Pseudomonas aeruginosa PA14 | 0.55 | IKLFDK_22630 | | NAD(P)/FAD-dependent oxidoreductase | 0.16 | IKLFDK_14890 | | TetR family transcriptional regulator | low | > 100 |
| Pseudomonas sp. RS175 | 0.54 | PFR28_04173 | | hypothetical protein | 0.18 | PFR28_02070 | | HTH-type transcriptional repressor ComR | low | > 88 |
| Pseudomonas simiae WCS417 | 0.54 | PS417_26375 | | membrane protein | 0.15 | PS417_19005 | | TetR family transcriptional regulator | — | — |
| Pseudomonas fluorescens FW300-N2E3 | 0.53 | AO353_07855 | | hypothetical protein | 0.22 | AO353_22630 | | TetR family transcriptional regulator | low | > 101 |
| Pseudomonas lactucae CFBP13502 | 0.53 | GEMAOFIL_05401 | | hypothetical protein | 0.16 | GEMAOFIL_04044 | | HTH-type transcriptional repressor ComR | low | > 93 |
| Sinorhizobium meliloti 1021 | 0.53 | SMc00763 | | hypothetical protein | 0.18 | SMa2381 | | hypothetical protein | low | > 103 |
| Pseudomonas syringae pv. syringae B728a ΔmexB | 0.52 | Psyr_0515 | | HI0933-like protein | 0.16 | Psyr_2927 | | transcriptional regulator, TetR family | low | > 86 |
| Pseudomonas syringae pv. syringae B728a | 0.52 | Psyr_0515 | | HI0933-like protein | 0.16 | Psyr_2927 | | transcriptional regulator, TetR family | low | > 86 |
| Rhizobium sp. OAE497 | 0.52 | ABIE40_RS03215 | | NAD(P)/FAD-dependent oxidoreductase | 0.22 | ABIE40_RS15965 | | TetR/AcrR family transcriptional regulator | 0.51 | 101 |
| Sphingomonas koreensis DSMZ 15582 | 0.48 | Ga0059261_3388 | | flavoprotein, HI0933 family | 0.18 | Ga0059261_3383 | | transcriptional regulator, TetR family | low | > 68 |
| Acinetobacter baumannii LAC-4 | 0.48 | RR41_RS15405 | | NAD(P)/FAD-dependent oxidoreductase | 0.18 | RR41_RS18100 | | TetR/AcrR family transcriptional regulator | low | > 55 |
| Herbaspirillum seropedicae SmR1 | 0.46 | HSERO_RS04345 | | membrane protein | 0.21 | HSERO_RS10085 | | transcriptional regulator | low | > 78 |
| Sphingobium sp. HT1-2 | 0.44 | GFF1279 | | Uncharacterized protein YhiN | 0.18 | GFF5241 | | Transcriptional regulator, AcrR family | low | > 95 |
| Paraburkholderia sabiae LMG 24235 | 0.44 | QEN71_RS15210 | | NAD(P)/FAD-dependent oxidoreductase | 0.18 | QEN71_RS10950 | | TetR/AcrR family transcriptional regulator | low | > 153 |
| Variovorax sp. OAS795 | 0.43 | ABID97_RS20650 | | NAD(P)/FAD-dependent oxidoreductase | 0.20 | ABID97_RS27540 | | TetR/AcrR family transcriptional regulator | — | — |
| Paraburkholderia graminis OAS925 | 0.43 | ABIE53_004862 | | putative Rossmann fold flavoprotein | 0.21 | ABIE53_004482 | | TetR/AcrR family transcriptional repressor of nem operon | low | > 113 |
| Burkholderia phytofirmans PsJN | 0.43 | BPHYT_RS33560 | | membrane protein | 0.22 | BPHYT_RS35800 | | TetR family transcriptional regulator | low | > 109 |
| Paraburkholderia bryophila 376MFSha3.1 | 0.43 | H281DRAFT_06012 | | hypothetical protein | 0.24 | H281DRAFT_05030 | | transcriptional regulator, TetR family | — | — |
| Dinoroseobacter shibae DFL-12 | 0.42 | Dshi_2710 | | HI0933 family protein (RefSeq) | 0.20 | Dshi_1874 | | transcriptional regulator, TetR family (RefSeq) | low | > 64 |
| Echinicola vietnamensis KMM 6221, DSM 17526 | 0.17 | Echvi_3335 | | flavoprotein, HI0933 family | 0.20 | Echvi_3929 | | Transcriptional regulator | low | > 79 |
| Cellulophaga baltica 18 | 0.14 | M666_RS02740 | | NAD(P)/FAD-dependent oxidoreductase | 0.18 | M666_RS10115 | | TetR/AcrR family transcriptional regulator | low | > 67 |
| Azospirillum sp. SherDot2 | 0.11 | MPMX19_00024 | | 3-dehydro-bile acid delta(4,6)-reductase | 0.19 | MPMX19_03586 | | HTH-type transcriptional repressor ComR | low | > 112 |
| Rhodopseudomonas palustris CGA009 | 0.10 | TX73_011285 | | NAD(P)/FAD-dependent oxidoreductase | 0.19 | TX73_015645 | | TetR/AcrR family transcriptional regulator | low | > 86 |
Not shown: 65 genomes with orthologs for CSW01_00430 only; 2 genomes with orthologs for CSW01_17160 only