Conservation of cofitness between CSW01_13550 and CSW01_13975 in Vibrio cholerae E7946 ATCC 55056

94 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Vibrio cholerae E7946 ATCC 55056 1.0 CSW01_13550 O-succinylhomoserine (thiol)-lyase 1.0 CSW01_13975 acetyl-CoA C-acyltransferase FadA 0.62 7
Pectobacterium carotovorum WPP14 0.60 HER17_RS00910 cystathionine gamma-synthase 0.79 HER17_RS20555 acetyl-CoA C-acyltransferase FadA low > 75
Enterobacter asburiae PDN3 0.59 EX28DRAFT_4411 cystathionine gamma-synthase (EC 2.5.1.48) 0.79 EX28DRAFT_4509 fatty oxidation complex, beta subunit FadA low > 76
Enterobacter sp. TBS_079 0.59 MPMX20_04531 Cystathionine gamma-synthase 0.79 MPMX20_04437 3-ketoacyl-CoA thiolase low > 85
Klebsiella pneumoniae MKP103 0.59 KDGMDA_09295 cystathionine gamma-synthase 0.78 KDGMDA_09850 acetyl-CoA C-acyltransferase FadA low > 95
Escherichia coli ECOR38 0.59 HEPCGN_12345 metB cystathionine gamma-synthase 0.78 HEPCGN_12880 fadA acetyl-CoA C-acyltransferase FadA low > 88
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.59 GFF2323 Cystathionine gamma-synthase (EC 2.5.1.48) 0.79 GFF272 3-ketoacyl-CoA thiolase (EC 2.3.1.16) @ Acetyl-CoA acetyltransferase (EC 2.3.1.9) low > 78
Escherichia coli Nissle 1917 0.59 ECOLIN_RS22725 cystathionine gamma-synthase 0.78 ECOLIN_RS22165 acetyl-CoA C-acyltransferase FadA low > 55
Escherichia coli BL21 0.59 ECD_03825 cystathionine gamma-synthase, PLP-dependent 0.78 ECD_03736 3-ketoacyl-CoA thiolase (thiolase I) low > 61
Escherichia coli HS(pFamp)R (ATCC 700891) 0.59 OHPLBJKB_04111 Cystathionine gamma-synthase 0.78 OHPLBJKB_04208 3-ketoacyl-CoA thiolase FadA low > 74
Escherichia coli BW25113 0.59 b3939 metB cystathionine gamma-synthase (NCBI) 0.78 b3845 fadA acetyl-CoA acetyltransferase (NCBI) low > 76
Escherichia fergusonii Becca 0.59 EFB2_04679 Cystathionine gamma-synthase 0.79 EFB2_04772 3-ketoacyl-CoA thiolase FadA low > 86
Shewanella sp. ANA-3 0.59 Shewana3_3614 cystathionine gamma-synthase (RefSeq) 0.79 Shewana3_0023 fadA Acetyl-CoA C-acyltransferase (EC 2.3.1.16) (from data) low > 73
Escherichia coli ECRC62 0.59 BNILDI_05715 metB cystathionine gamma-synthase 0.78 BNILDI_05150 fadA acetyl-CoA C-acyltransferase FadA low > 75
Serratia liquefaciens MT49 0.59 IAI46_24540 cystathionine gamma-synthase 0.81 IAI46_01125 acetyl-CoA C-acyltransferase FadA low > 87
Escherichia coli ECOR27 0.59 NOLOHH_05820 metB cystathionine gamma-synthase 0.78 NOLOHH_06380 fadA acetyl-CoA C-acyltransferase FadA low > 76
Shewanella amazonensis SB2B 0.59 Sama_3171 cystathionine gamma-synthase (RefSeq) 0.80 Sama_0031 fadA Acetyl-CoA C-acyltransferase (EC 2.3.1.16) (from data) low > 62
Escherichia coli ECRC98 0.59 JDDGAC_17300 metB cystathionine gamma-synthase 0.78 JDDGAC_17875 fadA acetyl-CoA C-acyltransferase FadA low > 87
Escherichia coli ECRC101 0.59 MCAODC_04175 metB cystathionine gamma-synthase 0.78 MCAODC_04755 fadA acetyl-CoA C-acyltransferase FadA low > 87
Escherichia coli ECRC99 0.59 KEDOAH_14485 metB cystathionine gamma-synthase 0.78 KEDOAH_13900 fadA acetyl-CoA C-acyltransferase FadA — —
Escherichia coli ECRC102 0.59 NIAGMN_11430 metB cystathionine gamma-synthase 0.78 NIAGMN_12005 fadA acetyl-CoA C-acyltransferase FadA low > 80
Escherichia coli ECRC100 0.59 OKFHMN_13675 metB cystathionine gamma-synthase 0.78 OKFHMN_14250 fadA acetyl-CoA C-acyltransferase FadA low > 79
Dickeya dadantii 3937 0.59 DDA3937_RS00950 cystathionine gamma-synthase 0.76 DDA3937_RS20255 acetyl-CoA C-acyltransferase FadA low > 74
Klebsiella michiganensis M5al 0.58 BWI76_RS00785 cystathionine gamma-synthase 0.78 BWI76_RS01360 acetyl-CoA C-acyltransferase FadA low > 92
Dickeya dianthicola 67-19 0.58 HGI48_RS20425 cystathionine gamma-synthase 0.76 HGI48_RS00970 acetyl-CoA C-acyltransferase FadA low > 71
Dickeya dianthicola ME23 0.58 DZA65_RS21470 cystathionine gamma-synthase 0.76 DZA65_RS01030 acetyl-CoA C-acyltransferase FadA low > 75
Kangiella aquimarina DSM 16071 0.58 B158DRAFT_2459 cystathionine gamma-synthase (EC 2.5.1.48) 0.69 B158DRAFT_0355 fatty oxidation complex, beta subunit FadA low > 40
Shewanella oneidensis MR-1 0.57 SO4056 metB cystathionine gamma-synthase (NCBI ptt file) 0.78 SO0020 fadA fatty oxidation complex, beta subunit (NCBI ptt file) low > 76
Shewanella loihica PV-4 0.56 Shew_0520 O-succinylhomoserine (thiol)-lyase (RefSeq) 0.80 Shew_0018 fadA 3-ketoacyl-CoA thiolase (RefSeq) low > 60
Rhodanobacter denitrificans MT42 0.56 LRK55_RS05085 cystathionine gamma-synthase 0.37 LRK55_RS18045 acetyl-CoA C-acyltransferase low > 63
Pantoea agglomerans CFBP13505 P0401 0.56 PagCFBP13505_RS18460 cystathionine gamma-synthase 0.78 PagCFBP13505_RS15210 acetyl-CoA C-acyltransferase FadA low > 74
Rahnella sp. WP5 0.56 EX31_RS14215 cystathionine gamma-synthase 0.82 EX31_RS14570 acetyl-CoA C-acyltransferase FadA low > 89
Pantoea sp. MT58 0.55 IAI47_00880 cystathionine gamma-synthase 0.77 IAI47_18235 acetyl-CoA C-acyltransferase FadA low > 76
Rhodanobacter denitrificans FW104-10B01 0.55 LRK54_RS05305 cystathionine gamma-synthase 0.37 LRK54_RS00050 acetyl-CoA C-acyltransferase low > 59
Rhodanobacter sp. FW510-T8 0.55 OKGIIK_01515 metB cystathionine gamma-synthase 0.36 OKGIIK_07160 paaJ acetyl-CoA C-acyltransferase low > 53
Dyella japonica UNC79MFTsu3.2 0.54 ABZR86_RS19030 cystathionine gamma-synthase 0.39 ABZR86_RS05475 acetyl-CoA C-acyltransferase low > 74
Rhodanobacter sp000427505 FW510-R12 0.54 LRK53_RS04700 cystathionine gamma-synthase 0.36 LRK53_RS11215 acetyl-CoA C-acyltransferase low > 59
Erwinia amylovora T8 0.54 OLJFJH_06095 cystathionine gamma-synthase 0.75 OLJFJH_06550 acetyl-CoA C-acyltransferase FadA low > 58
Brevundimonas sp. GW460-12-10-14-LB2 0.54 A4249_RS16160 cystathionine gamma-synthase 0.32 A4249_RS11165 acetyl-CoA C-acyltransferase low > 48
Xanthomonas campestris pv. campestris strain 8004 0.53 Xcc-8004.1596.1 hypothetical protein 0.38 Xcc-8004.2741.1 3-ketoacyl-CoA thiolase (EC 2.3.1.16) @ Acetyl-CoA acetyltransferase (EC 2.3.1.9) low > 74
Cellulophaga baltica 18 0.39 M666_RS03785 cystathionine gamma-synthase 0.36 M666_RS18280 acetyl-CoA C-acyltransferase low > 67
Pseudomonas fluorescens FW300-N2E3 0.38 AO353_23295 cystathionine beta-lyase 0.64 AO353_00505 3-ketoacyl-CoA thiolase low > 101
Pseudomonas sp. DMC3 0.38 GFF3060 Cystathionine beta-lyase 0.65 GFF1272 3-ketoacyl-CoA thiolase low > 89
Pseudomonas fluorescens FW300-N1B4 0.38 Pf1N1B4_4890 Cystathionine gamma-lyase (EC 4.4.1.1) 0.65 Pf1N1B4_3904 3-ketoacyl-CoA thiolase (EC 2.3.1.16) @ Acetyl-CoA acetyltransferase (EC 2.3.1.9) — —
Pseudomonas aeruginosa MRSN321 0.37 DY961_RS21980 cystathionine gamma-synthase 0.65 DY961_RS01900 fadA;go_function=acetyl-CoA acetyl-CoA C-acyltransferase FadA — —
Mycobacterium tuberculosis H37Rv 0.37 Rv1079 Cystathionine gamma-synthase MetB (CGS) (O-succinylhomoserine [thiol]-lyase) 0.36 Rv1074c Probable beta-ketoacyl CoA thiolase FadA3 low > 58
Pseudomonas sp. SVBP6 0.37 COO64_RS14890 cystathionine gamma-synthase 0.64 COO64_RS09400 fadA acetyl-CoA C-acyltransferase FadA low > 93
Pseudomonas aeruginosa PA14 0.37 IKLFDK_23420 cystathionine gamma-synthase 0.65 IKLFDK_15330 acetyl-CoA C-acyltransferase FadA — —
Pseudomonas aeruginosa PUPa3 0.37 DQ20_RS37320 cystathionine gamma-synthase 0.65 DQ20_RS33680 fadA;go_function=acetyl-CoA acetyl-CoA C-acyltransferase FadA — —
Pseudomonas lactucae CFBP13502 0.37 GEMAOFIL_02861 Cystathionine beta-lyase 0.64 GEMAOFIL_01648 3-ketoacyl-CoA thiolase low > 96
Pontibacter actiniarum KMM 6156, DSM 19842 0.37 CA264_20315 cystathionine gamma-synthase 0.41 CA264_17720 beta-ketoadipyl CoA thiolase low > 74
Pseudomonas orientalis W4I3 0.36 QF045_RS15175 cystathionine gamma-synthase 0.64 QF045_RS10220 acetyl-CoA C-acyltransferase FadA low > 93
Pseudomonas fluorescens SBW25 0.36 PFLU_RS16625 cystathionine gamma-synthase 0.64 PFLU_RS07655 acetyl-CoA C-acyltransferase FadA low > 109
Pseudomonas fluorescens SBW25-INTG 0.36 PFLU_RS16625 cystathionine gamma-synthase 0.64 PFLU_RS07655 acetyl-CoA C-acyltransferase FadA low > 109
Dechlorosoma suillum PS 0.35 Dsui_2042 cystathionine beta-lyase/cystathionine gamma-synthase 0.38 Dsui_0317 acetyl-CoA acetyltransferase low > 51
Rhodospirillum rubrum S1H 0.35 Rru_A0786 Cystathionine gamma-synthase (NCBI) 0.39 Rru_A1310 Acetyl-CoA C-acyltransferase (NCBI) low > 58
Pseudomonas putida KT2440 0.34 PP_4594 putative Cystathionine gamma-synthase 0.65 PP_2137 beta-ketoadipyl CoA thiolase, beta component low > 96
Pseudomonas sp. BP01 0.34 JOY50_RS01570 PLP-dependent aspartate aminotransferase family protein 0.65 JOY50_RS25040 fadA acetyl-CoA C-acyltransferase FadA low > 84
Pseudomonas segetis P6 0.33 ACVTMO_RS05450 trans-sulfuration enzyme family protein 0.64 ACVTMO_RS14830 fadA acetyl-CoA C-acyltransferase FadA low > 75
Pseudomonas stutzeri RCH2 0.32 Psest_2578 O-succinylhomoserine sulfhydrylase 0.64 Psest_2653 fatty oxidation complex, beta subunit FadA — —
Pseudomonas simiae WCS417 0.32 PS417_11735 methionine gamma-lyase 0.64 PS417_07580 3-ketoacyl-CoA thiolase — —
Acinetobacter radioresistens SK82 0.32 MPMX26_01645 O-succinylhomoserine sulfhydrylase 0.62 MPMX26_00225 3-ketoacyl-CoA thiolase low > 36
Azospirillum sp. SherDot2 0.32 MPMX19_06514 L-methionine gamma-lyase 0.40 MPMX19_06951 Beta-ketoadipyl-CoA thiolase — —
Acinetobacter baumannii LAC-4 0.31 RR41_RS12630 O-succinylhomoserine sulfhydrylase 0.62 RR41_RS17455 acetyl-CoA C-acyltransferase FadA low > 55
Pseudomonas sp. S08-1 0.31 OH686_04415 O-succinylhomoserine sulfhydrylase 0.64 OH686_21930 acetyl-CoA C-acyltransferase FadA low > 80
Acidovorax sp. GW101-3H11 0.31 Ac3H11_34 Methionine gamma-lyase (EC 4.4.1.11) 0.37 Ac3H11_3920 Acetyl-CoA acetyltransferase (EC 2.3.1.9) @ Beta-ketoadipyl CoA thiolase (EC 2.3.1.-) low > 79
Pseudomonas fluorescens GW456-L13 0.30 PfGW456L13_3934 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) 0.65 PfGW456L13_4040 3-ketoacyl-CoA thiolase (EC 2.3.1.16) @ Acetyl-CoA acetyltransferase (EC 2.3.1.9) low > 87
Pseudomonas sp. RS175 0.30 PFR28_02810 O-succinylhomoserine sulfhydrylase 0.65 PFR28_01111 3-ketoacyl-CoA thiolase low > 88
Pseudomonas fluorescens FW300-N2E2 0.30 Pf6N2E2_77 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) 0.64 Pf6N2E2_2289 3-ketoacyl-CoA thiolase (EC 2.3.1.16) @ Acetyl-CoA acetyltransferase (EC 2.3.1.9) — —
Pseudomonas fluorescens FW300-N2C3 0.30 AO356_21470 O-succinylhomoserine sulfhydrylase 0.65 AO356_02325 3-ketoacyl-CoA thiolase low > 104
Castellaniella sp019104865 MT123 0.30 ABCV34_RS15785 aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme 0.37 ABCV34_RS11125 acetyl-CoA C-acyltransferase low > 48
Pseudomonas syringae pv. syringae B728a 0.30 Psyr_1669 O-succinylhomoserine sulfhydrylase 0.65 Psyr_3289 3-ketoacyl-CoA thiolase low > 86
Pseudomonas syringae pv. syringae B728a ΔmexB 0.30 Psyr_1669 O-succinylhomoserine sulfhydrylase 0.65 Psyr_3289 3-ketoacyl-CoA thiolase low > 86
Rhodopseudomonas palustris CGA009 0.30 TX73_012185 PLP-dependent aspartate aminotransferase family protein 0.37 TX73_002660 3-oxoadipyl-CoA thiolase low > 86
Hydrogenophaga sp. GW460-11-11-14-LB1 0.29 GFF301 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) 0.37 GFF415 3-ketoacyl-CoA thiolase (EC 2.3.1.16) @ Acetyl-CoA acetyltransferase (EC 2.3.1.9) low > 90
Variovorax sp. SCN45 0.28 GFF3088 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) @ O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) 0.39 GFF2768 3-ketoacyl-CoA thiolase 2 [fadN-fadA-fadE operon] (EC 2.3.1.16) — —
Azospirillum brasilense Sp245 0.27 AZOBR_RS11340 O-acetylhomoserine aminocarboxypropyltransferase 0.40 AZOBR_RS20220 acetyl-CoA acetyltransferase low > 97
Magnetospirillum magneticum AMB-1 0.27 AMB_RS21365 O-succinylhomoserine sulfhydrylase 0.39 AMB_RS13850 3-oxoadipyl-CoA thiolase — —
Ralstonia sp. UNC404CL21Col 0.27 ABZR87_RS17575 aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme 0.38 ABZR87_RS15790 3-oxoadipyl-CoA thiolase low > 80
Marinobacter adhaerens HP15 0.27 HP15_1820 methionine gamma-lyase 0.66 HP15_1513 Acetyl-CoA C-acyltransferase (EC 2.3.1.16) (from data) low > 73
Variovorax sp. OAS795 0.27 ABID97_RS21630 O-succinylhomoserine sulfhydrylase 0.39 ABID97_RS20240 thiolase family protein — —
Sphingobium sp. HT1-2 0.27 GFF3455 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) @ O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) 0.40 GFF4747 3-ketoacyl-CoA thiolase 2 [fadN-fadA-fadE operon] (EC 2.3.1.16) low > 95
Agrobacterium fabrum C58 0.27 Atu0432 O-succinylhomoserine sulfhydrylase 0.35 Atu4549 beta-ketoadipyl CoA thiolase low > 89
Paraburkholderia bryophila 376MFSha3.1 0.26 H281DRAFT_06059 O-succinylhomoserine sulfhydrylase 0.38 H281DRAFT_05723 bifunctional thiolase PaaJ: 3-oxo-5,6-didehydrosuberyl-CoA thiolase (EC 2.3.1.223); 3-oxoadipyl-CoA thiolase (EC 2.3.1.174) (from data) low > 103
Dinoroseobacter shibae DFL-12 0.26 Dshi_1002 Cystathionine gamma-synthase (RefSeq) 0.34 Dshi_3817 beta-ketoadipyl CoA thiolase (RefSeq) low > 64
Burkholderia phytofirmans PsJN 0.26 BPHYT_RS33835 O-succinylhomoserine sulfhydrylase 0.37 BPHYT_RS17345 bifunctional thiolase PaaJ: 3-oxo-5,6-didehydrosuberyl-CoA thiolase (EC 2.3.1.223); 3-oxoadipyl-CoA thiolase (EC 2.3.1.174) (from data) low > 109
Cupriavidus basilensis FW507-4G11 0.26 RR42_RS06465 O-acetylhomoserine aminocarboxypropyltransferase 0.37 RR42_RS02515 acetyl-CoA acetyltransferase — —
Paraburkholderia graminis OAS925 0.26 ABIE53_004817 O-succinylhomoserine sulfhydrylase 0.37 ABIE53_003631 acetyl-CoA acyltransferase low > 113
Ralstonia solanacearum IBSBF1503 0.25 RALBFv3_RS01870 O-acetylhomoserine aminocarboxypropyltransferase 0.38 RALBFv3_RS03860 3-oxoadipyl-CoA thiolase low > 76
Ralstonia solanacearum UW163 0.25 UW163_RS15180 O-acetylhomoserine aminocarboxypropyltransferase 0.38 UW163_RS09810 3-oxoadipyl-CoA thiolase — —
Xanthobacter sp. DMC5 0.25 GFF697 O-acetyl-L-homoserine sulfhydrylase 0.41 GFF518 3-ketoacyl-CoA thiolase — —
Ralstonia solanacearum GMI1000 0.25 RS_RS07865 O-acetylhomoserine aminocarboxypropyltransferase 0.37 RS_RS11305 3-oxoadipyl-CoA thiolase low > 80
Ralstonia solanacearum PSI07 0.25 RPSI07_RS15620 O-acetylhomoserine aminocarboxypropyltransferase 0.37 RPSI07_RS13370 3-oxoadipyl-CoA thiolase low > 81
Herbaspirillum seropedicae SmR1 0.22 HSERO_RS18310 O-acetylhomoserine aminocarboxypropyltransferase 0.37 HSERO_RS20660 bifunctional thiolase PaaJ: 3-oxo-5,6-dehydrosuberyl-CoA thiolase (EC 2.3.1.223); 3-oxoadipyl-CoA thiolase (EC 2.3.1.174) (from data) low > 78
Alteromonas macleodii MIT1002 0.19 MIT1002_02266 Methionine gamma-lyase 0.73 MIT1002_00574 3-ketoacyl-CoA thiolase low > 70

Not shown: 24 genomes with orthologs for CSW01_13550 only; 0 genomes with orthologs for CSW01_13975 only