Conservation of cofitness between CSW01_09720 and CSW01_11560 in Vibrio cholerae E7946 ATCC 55056

115 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Vibrio cholerae E7946 ATCC 55056 1.0 CSW01_09720 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD 1.0 CSW01_11560 riboflavin biosynthesis protein RibD 0.80 13
Rahnella sp. WP5 0.69 EX31_RS22835 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD 0.53 EX31_RS22125 bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD
Klebsiella michiganensis M5al 0.68 BWI76_RS07100 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase 0.52 BWI76_RS06350 bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase
Serratia liquefaciens MT49 0.68 IAI46_05400 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD 0.53 IAI46_04895 bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD
Klebsiella pneumoniae MKP103 0.68 KDGMDA_15035 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD 0.53 KDGMDA_14440 bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD
Enterobacter asburiae PDN3 0.68 EX28DRAFT_2449 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase 0.53 EX28DRAFT_2556 diaminohydroxyphosphoribosylaminopyrimidine deaminase (EC 3.5.4.26)
Pantoea sp. MT58 0.68 IAI47_14320 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD 0.53 IAI47_14770 bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD
Shewanella amazonensis SB2B 0.68 Sama_1222 methylenetetrahydrofolate dehydrogenase (NADP(+)) (RefSeq) 0.48 Sama_1016 diaminohydroxyphosphoribosylaminopyrimidine deaminase., 5-amino-6-(5-phosphoribosylamino)uracil reductase (RefSeq)
Enterobacter sp. TBS_079 0.68 MPMX20_01107 Bifunctional protein FolD protein 0.51 MPMX20_01006 Riboflavin biosynthesis protein RibD
Escherichia coli BW25113 0.68 b0529 folD bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase (NCBI) 0.53 b0414 ribD fused diaminohydroxyphosphoribosylaminopyrimidine deaminase and 5-amino-6-(5-phosphoribosylamino) uracil reductase (NCBI)
Escherichia coli HS(pFamp)R (ATCC 700891) 0.68 OHPLBJKB_03152 Bifunctional protein FolD protein 0.53 OHPLBJKB_03262 Riboflavin biosynthesis protein RibD
Escherichia coli ECRC102 0.68 NIAGMN_05860 Bifunctional protein FolD 0.51 NIAGMN_06510 ribD bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD
Escherichia coli ECRC98 0.68 JDDGAC_11455 Bifunctional protein FolD 0.51 JDDGAC_12110 ribD bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD
Shewanella sp. ANA-3 0.68 Shewana3_2663 methenyltetrahydrofolate cyclohydrolase (RefSeq) 0.50 Shewana3_1096 5-amino-6-(5-phosphoribosylamino)uracil reductase / diaminohydroxyphosphoribosylaminopyrimidine deaminase (RefSeq)
Escherichia fergusonii Becca 0.68 EFB2_03532 Bifunctional protein FolD protein 0.51 EFB2_03643 Riboflavin biosynthesis protein RibD
Escherichia coli ECRC101 0.68 MCAODC_27025 Bifunctional protein FolD 0.51 MCAODC_27680 ribD bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD
Escherichia coli ECOR27 0.68 NOLOHH_00795 Bifunctional protein FolD 0.53 NOLOHH_01400 ribD bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.68 GFF4447 Methylenetetrahydrofolate dehydrogenase (NADP+) (EC 1.5.1.5) / Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9) 0.48 GFF4318 Diaminohydroxyphosphoribosylaminopyrimidine deaminase (EC 3.5.4.26) / 5-amino-6-(5-phosphoribosylamino)uracil reductase (EC 1.1.1.193)
Pantoea agglomerans CFBP13505 P0401 0.68 PagCFBP13505_RS10890 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD 0.54 PagCFBP13505_RS10425 bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD
Escherichia coli ECRC100 0.68 OKFHMN_07805 Bifunctional protein FolD 0.51 OKFHMN_08455 ribD bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD
Escherichia coli Nissle 1917 0.68 ECOLIN_RS03065 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD 0.51 ECOLIN_RS02505 bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD
Escherichia coli ECRC99 0.68 KEDOAH_20165 Bifunctional protein FolD 0.51 KEDOAH_19510 ribD bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD
Escherichia coli BL21 0.68 ECD_00479 bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase 0.53 ECD_00362 fused diaminohydroxyphosphoribosylaminopyrimidine deaminase and 5-amino-6-(5-phosphoribosylamino) uracil reductase
Escherichia coli ECOR38 0.67 HEPCGN_06445 Bifunctional protein FolD 0.52 HEPCGN_07080 ribD bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD
Escherichia coli ECRC62 0.67 BNILDI_22225 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD 0.53 BNILDI_22815 ribD bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD
Erwinia amylovora T8 0.67 OLJFJH_17600 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD 0.54 OLJFJH_18090 bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD
Dickeya dadantii 3937 0.67 DDA3937_RS15075 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD 0.50 DDA3937_RS05505 bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD
Pectobacterium carotovorum WPP14 0.67 HER17_RS06505 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD 0.55 HER17_RS15960 bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD
Shewanella loihica PV-4 0.67 Shew_2510 methylenetetrahydrofolate dehydrogenase (NADP(+)) (RefSeq) 0.52 Shew_1187 riboflavin biosynthesis protein RibD (RefSeq)
Alteromonas macleodii MIT1002 0.66 MIT1002_02770 hypothetical protein 0.44 MIT1002_02700 Riboflavin biosynthesis protein RibD
Dickeya dianthicola 67-19 0.66 HGI48_RS15155 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD 0.50 HGI48_RS05565 bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD
Shewanella oneidensis MR-1 0.66 SO1792 folD methylenetetrahydrofolate dehydrogenase/methylenetetrahydrofolate cyclohydrolase (NCBI ptt file) 0.50 SO3469 ribD riboflavin biosynthesis protein RibD (NCBI ptt file)
Erwinia tracheiphila SCR3 0.66 LU632_RS15195 folD bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD 0.51 LU632_RS18595 ribD bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD
Erwinia tracheiphila HP pepo 2.2 0.66 IJEDHG_00975 folD bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD 0.51 IJEDHG_25995 ribD bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD
Dickeya dianthicola ME23 0.66 DZA65_RS15960 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD 0.50 DZA65_RS05890 bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD
Pseudomonas simiae WCS417 0.62 PS417_17265 methenyltetrahydrofolate cyclohydrolase 0.44 PS417_25265 diaminohydroxyphosphoribosylaminopyrimidine deaminase
Pseudomonas sp. S08-1 0.62 OH686_03670 Methenyltetrahydrofolate cyclohydrolase / Methylenetetrahydrofolate dehydrogenase (NADP+) 0.46 OH686_15695 riboflavin biosynthesis protein RibD
Pseudomonas aeruginosa PUPa3 0.62 DQ20_RS54755 folD;go_function=methylenetetrahydrofolate bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD 0.47 DQ20_RS47900 ribD;go_function=5-amino-6-(5-phosphoribosylamino)uracil bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD
Pseudomonas aeruginosa PA14 0.62 IKLFDK_08690 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD 0.47 IKLFDK_20910 bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD
Pseudomonas orientalis W4I3 0.62 QF045_RS18930 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD 0.46 QF045_RS27230 bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD
Pseudomonas aeruginosa MRSN321 0.62 DY961_RS20675 folD;go_function=methylenetetrahydrofolate bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD 0.47 DY961_RS27745 ribD;go_function=5-amino-6-(5-phosphoribosylamino)uracil bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD
Pseudomonas fluorescens GW456-L13 0.62 PfGW456L13_2550 Methylenetetrahydrofolate dehydrogenase (NADP+) (EC 1.5.1.5) / Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9) 0.47 PfGW456L13_1313 Diaminohydroxyphosphoribosylaminopyrimidine deaminase (EC 3.5.4.26) / 5-amino-6-(5-phosphoribosylamino)uracil reductase (EC 1.1.1.193)
Pseudomonas sp. RS175 0.61 PFR28_01223 Bifunctional protein FolD protein 0.48 PFR28_03949 Riboflavin biosynthesis protein RibD
Pseudomonas fluorescens FW300-N2C3 0.61 AO356_01775 bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/5,10-methylene-tetrahydrofolate cyclohydrolase 0.48 AO356_14930 diaminohydroxyphosphoribosylaminopyrimidine deaminase
Marinobacter adhaerens HP15 0.61 HP15_2187 methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase 0.45 HP15_492 bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase
Pseudomonas fluorescens SBW25 0.61 PFLU_RS19200 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD 0.47 PFLU_RS26900 bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD
Pseudomonas putida KT2440 0.61 PP_2265 methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase 0.46 PP_0514 bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase
Pseudomonas fluorescens FW300-N2E2 0.61 Pf6N2E2_2221 Methylenetetrahydrofolate dehydrogenase (NADP+) (EC 1.5.1.5) / Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9) 0.48 Pf6N2E2_4919 Diaminohydroxyphosphoribosylaminopyrimidine deaminase (EC 3.5.4.26) / 5-amino-6-(5-phosphoribosylamino)uracil reductase (EC 1.1.1.193)
Pseudomonas lactucae CFBP13502 0.61 GEMAOFIL_03749 Bifunctional protein FolD protein 0.47 GEMAOFIL_05158 Riboflavin biosynthesis protein RibD
Pseudomonas fluorescens SBW25-INTG 0.61 PFLU_RS19200 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD 0.47 PFLU_RS26900 bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD
Pseudomonas fluorescens FW300-N1B4 0.61 Pf1N1B4_3943 Methylenetetrahydrofolate dehydrogenase (NADP+) (EC 1.5.1.5) / Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9) 0.47 Pf1N1B4_2649 Diaminohydroxyphosphoribosylaminopyrimidine deaminase (EC 3.5.4.26) / 5-amino-6-(5-phosphoribosylamino)uracil reductase (EC 1.1.1.193)
Pseudomonas sp. SVBP6 0.61 COO64_RS19115 folD bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD 0.47 COO64_RS15890 ribD bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD
Pseudomonas sp. DMC3 0.61 GFF1441 Bifunctional protein FolD protein 0.47 GFF3827 Riboflavin biosynthesis protein RibD
Pseudomonas sp. BP01 0.61 JOY50_RS25950 folD bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD 0.46 JOY50_RS20125 ribD bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD
Pseudomonas fluorescens FW300-N2E3 0.61 AO353_20145 bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/5,10-methylene-tetrahydrofolate cyclohydrolase 0.48 AO353_06715 diaminohydroxyphosphoribosylaminopyrimidine deaminase
Pseudomonas segetis P6 0.60 MPMX49_02256 Bifunctional protein FolD protein 0.47 MPMX49_00990 Riboflavin biosynthesis protein RibD
Pseudomonas syringae pv. syringae B728a ΔmexB 0.60 Psyr_1743 methenyltetrahydrofolate cyclohydrolase / 5,10-methylenetetrahydrofolate dehydrogenase (NADP+) 0.46 Psyr_4462 diaminohydroxyphosphoribosylaminopyrimidine deaminase / 5-amino-6-(5-phosphoribosylamino)uracil reductase
Pseudomonas syringae pv. syringae B728a 0.60 Psyr_1743 methenyltetrahydrofolate cyclohydrolase / 5,10-methylenetetrahydrofolate dehydrogenase (NADP+) 0.46 Psyr_4462 diaminohydroxyphosphoribosylaminopyrimidine deaminase / 5-amino-6-(5-phosphoribosylamino)uracil reductase
Pseudomonas stutzeri RCH2 0.58 Psest_2301 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase 0.47 Psest_3552 riboflavin biosynthesis protein RibD
Kangiella aquimarina DSM 16071 0.57 B158DRAFT_1028 methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)/5,10-methylenetetrahydrofolate dehydrogenase (NADP+) (EC 1.5.1.5) 0.43 B158DRAFT_1910 diaminohydroxyphosphoribosylaminopyrimidine deaminase (EC 3.5.4.26)
Rhodanobacter sp000427505 FW510-R12 0.56 LRK53_RS11165 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD 0.41 LRK53_RS05400 bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD
Rhodanobacter denitrificans FW104-10B01 0.55 LRK54_RS00100 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD 0.41 LRK54_RS04610 bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD
Rhodanobacter denitrificans MT42 0.55 LRK55_RS18095 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD 0.41 LRK55_RS04385 bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD
Rhodanobacter sp. FW510-T8 0.54 OKGIIK_07100 folD bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD 0.41 OKGIIK_11430 ribD bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD
Dyella japonica UNC79MFTsu3.2 0.54 ABZR86_RS05415 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD 0.40 ABZR86_RS10705 bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD
Lysobacter sp. OAE881 0.52 ABIE51_RS09470 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD 0.45 ABIE51_RS04630 bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD
Xanthomonas campestris pv. campestris strain 8004 0.51 Xcc-8004.2390.1 Methylenetetrahydrofolate dehydrogenase (NADP+) (EC 1.5.1.5) / Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9) 0.43 Xcc-8004.4395.1 Diaminohydroxyphosphoribosylaminopyrimidine deaminase (EC 3.5.4.26) / 5-amino-6-(5-phosphoribosylamino)uracil reductase (EC 1.1.1.193)
Castellaniella sp019104865 MT123 0.48 ABCV34_RS04175 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD 0.30 ABCV34_RS10545 bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD
Herbaspirillum seropedicae SmR1 0.46 HSERO_RS07295 bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase 0.39 HSERO_RS18235 diaminohydroxyphosphoribosylaminopyrimidine deaminase
Cupriavidus basilensis FW507-4G11 0.46 RR42_RS07345 methenyltetrahydrofolate cyclohydrolase 0.41 RR42_RS15555 diaminohydroxyphosphoribosylaminopyrimidine deaminase
Desulfovibrio vulgaris Hildenborough JW710 0.46 DVU0323 folD methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase (TIGR) 0.27 DVU1201 ribD riboflavin biosynthesis protein RibD (TIGR)
Dechlorosoma suillum PS 0.46 Dsui_0093 5,10-methylene-tetrahydrofolate dehydrogenase/methenyl tetrahydrofolate cyclohydrolase 0.37 Dsui_1267 riboflavin biosynthesis protein RibD
Hydrogenophaga sp. GW460-11-11-14-LB1 0.45 GFF4894 Methylenetetrahydrofolate dehydrogenase (NADP+) (EC 1.5.1.5) / Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9) 0.31 GFF5160 Diaminohydroxyphosphoribosylaminopyrimidine deaminase (EC 3.5.4.26) / 5-amino-6-(5-phosphoribosylamino)uracil reductase (EC 1.1.1.193)
Ralstonia solanacearum PSI07 0.45 RPSI07_RS15800 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD 0.42 RPSI07_RS20395 bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD
Ralstonia solanacearum UW163 0.45 UW163_RS14995 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD 0.42 UW163_RS00740 bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD
Ralstonia solanacearum IBSBF1503 0.45 RALBFv3_RS01685 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD 0.42 RALBFv3_RS12825 bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD
Ralstonia sp. UNC404CL21Col 0.45 ABZR87_RS13485 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD 0.43 ABZR87_RS08885 bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD
Ralstonia solanacearum GMI1000 0.45 RS_RS08040 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase 0.42 RS_RS03600 bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD
Magnetospirillum magneticum AMB-1 0.45 AMB_RS22130 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase 0.31 AMB_RS11825 bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD
Acidovorax sp. GW101-3H11 0.45 Ac3H11_4096 Methylenetetrahydrofolate dehydrogenase (NADP+) (EC 1.5.1.5) / Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9) 0.30 Ac3H11_1461 Diaminohydroxyphosphoribosylaminopyrimidine deaminase (EC 3.5.4.26) / 5-amino-6-(5-phosphoribosylamino)uracil reductase (EC 1.1.1.193)
Variovorax sp. SCN45 0.44 GFF964 Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9) / Methylenetetrahydrofolate dehydrogenase (NADP+) (EC 1.5.1.5) 0.35 GFF568 Diaminohydroxyphosphoribosylaminopyrimidine deaminase (EC 3.5.4.26) / 5-amino-6-(5-phosphoribosylamino)uracil reductase (EC 1.1.1.193)
Variovorax sp. OAS795 0.44 ABID97_RS14085 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD 0.38 ABID97_RS17935 bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD
Echinicola vietnamensis KMM 6221, DSM 17526 0.43 Echvi_4643 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase 0.28 Echvi_0964 riboflavin biosynthesis protein RibD
Synechococcus elongatus PCC 7942 0.43 Synpcc7942_0777 folD Methenyltetrahydrofolate cyclohydrolase 0.33 Synpcc7942_0203 ribD 5-amino-6-(5-phosphoribosylamino)uracil reductase / diaminohydroxyphosphoribosylaminopyrimidine deaminase
Paraburkholderia sabiae LMG 24235 0.43 QEN71_RS05700 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD 0.42 QEN71_RS03300 bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD
Desulfovibrio vulgaris Miyazaki F 0.43 DvMF_1809 Methenyltetrahydrofolate cyclohydrolase (RefSeq) 0.24 DvMF_3095 riboflavin biosynthesis protein RibD (RefSeq)
Pontibacter actiniarum KMM 6156, DSM 19842 0.43 CA264_07145 bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/5,10-methylene-tetrahydrofolate cyclohydrolase 0.27 CA264_17890 bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase
Synechocystis sp000284455 PCC 6803 0.43 SGL_RS13155 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD 0.30 SGL_RS13965 bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD
Phaeobacter inhibens DSM 17395 0.43 PGA1_c06010 bifunctional protein FolD 0.33 PGA1_c08870 riboflavin biosynthesis protein RibD
Burkholderia phytofirmans PsJN 0.42 BPHYT_RS12865 bifunctional protein FolD 0.40 BPHYT_RS15380 diaminohydroxyphosphoribosylaminopyrimidine deaminase
Paraburkholderia graminis OAS925 0.42 ABIE53_002796 methylenetetrahydrofolate dehydrogenase (NADP+)/methenyltetrahydrofolate cyclohydrolase 0.40 ABIE53_003242 diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase
Xanthobacter sp. DMC5 0.42 GFF1063 Bifunctional protein FolD protein 0.24 GFF577 Riboflavin biosynthesis protein RibD
Paraburkholderia bryophila 376MFSha3.1 0.42 H281DRAFT_00463 methenyltetrahydrofolate cyclohydrolase /5,10-methylenetetrahydrofolate dehydrogenase (NADP+) 0.40 H281DRAFT_04019 diaminohydroxyphosphoribosylaminopyrimidine deaminase
Rhodospirillum rubrum S1H 0.42 Rru_A0557 Methenyltetrahydrofolate cyclohydrolase (NCBI) 0.27 Rru_A1825 bifunctional deaminase-reductase (NCBI)
Parabacteroides merdae CL09T00C40 0.42 HMPREF1078_RS14700 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD 0.28 HMPREF1078_RS11285 bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD
Bosea sp. OAE506 0.42 ABIE41_RS08995 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD 0.23 ABIE41_RS19760 bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD
Sphingomonas koreensis DSMZ 15582 0.42 Ga0059261_2527 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase 0.26 Ga0059261_2336 diaminohydroxyphosphoribosylaminopyrimidine deaminase (EC 3.5.4.26)
Cellulophaga baltica 18 0.41 M666_RS00795 bifunctional 5,10-methylenetetrahydrofolate dehydrogenase/5,10-methenyltetrahydrofolate cyclohydrolase 0.24 M666_RS17750 bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD
Phocaeicola dorei CL03T12C01 0.41 ABI39_RS10870 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD 0.26 ABI39_RS07065 bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD
Phocaeicola vulgatus CL09T03C04 0.41 HMPREF1058_RS15075 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD 0.27 HMPREF1058_RS09615 bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD
Bacteroides thetaiotaomicron VPI-5482 0.41 BT1607 methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase (NCBI ptt file) 0.27 BT3728 riboflavin biosynthesis protein ribD (NCBI ptt file)
Bacteroides ovatus ATCC 8483 0.41 BACOVA_04344 tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain protein 0.27 BACOVA_03546 riboflavin biosynthesis protein RibD
Azospirillum brasilense Sp245 0.40 AZOBR_RS00650 5 10-methylene-tetrahydrofolate dehydrogenase 0.28 AZOBR_RS10025 5-amino-6-(5-phosphoribosylamino)uracil reductase
Bacteroides stercoris CC31F 0.40 HMPREF1181_RS11305 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD 0.24 HMPREF1181_RS03385 bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD
Azospirillum sp. SherDot2 0.40 MPMX19_02743 Bifunctional protein FolD protein 0.31 MPMX19_00736 Riboflavin biosynthesis protein RibD
Rhodopseudomonas palustris CGA009 0.39 TX73_002145 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD 0.31 TX73_014125 bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD
Mucilaginibacter yixingensis YX-36 DSM 26809 0.39 ABZR88_RS09400 bifunctional 5,10-methylenetetrahydrofolate dehydrogenase/5,10-methenyltetrahydrofolate cyclohydrolase 0.26 ABZR88_RS10210 bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD
Sphingobium sp. HT1-2 0.39 GFF2785 Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9) / Methylenetetrahydrofolate dehydrogenase (NADP+) (EC 1.5.1.5) 0.28 GFF3255 Diaminohydroxyphosphoribosylaminopyrimidine deaminase (EC 3.5.4.26) / 5-amino-6-(5-phosphoribosylamino)uracil reductase (EC 1.1.1.193)
Sinorhizobium meliloti 1021 0.38 SMc03059 bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase 0.26 SMc01772 riboflavin biosynthesis protein
Pedobacter sp. GW460-11-11-14-LB5 0.38 CA265_RS08950 bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/5,10-methylene-tetrahydrofolate cyclohydrolase 0.24 CA265_RS09530 riboflavin biosynthesis protein RibD
Dinoroseobacter shibae DFL-12 0.37 Dshi_1285 Methylenetetrahydrofolate dehydrogenase (NADP(+)) (RefSeq) 0.25 Dshi_2256 riboflavin biosynthesis protein RibD (RefSeq)
Agrobacterium fabrum C58 0.36 Atu0589 methylenetetrahydrofolate dehydrogenase 0.24 Atu8148 bifunctional riboflavin deaminase-reductase
Acinetobacter radioresistens SK82 0.35 MPMX26_00777 Bifunctional protein FolD protein 0.44 MPMX26_00152 Riboflavin biosynthesis protein RibD
Fusobacterium nucleatum SB010 0.35 HUW76_09060 bifunctional 5,10-methylenetetrahydrofolate dehydrogenase/5,10-methenyltetrahydrofolate cyclohydrolase 0.32 HUW76_09285 bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD
Acinetobacter baumannii LAC-4 0.35 RR41_RS04225 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD 0.42 RR41_RS17855 bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD
Mycobacterium tuberculosis H37Rv 0.34 Rv3356c Probable bifunctional protein FolD: methylenetetrahydrofolate dehydrogenase + methenyltetrahydrofolate cyclohydrolase 0.24 Rv1409 Probable bifunctional riboflavin biosynthesis protein RibG : diaminohydroxyphosphoribosylaminopyrimidine deaminase (riboflavin-specific deaminase) + 5-amino-6-(5-phosphoribosylamino) uracil reductase (HTP reductase)

Not shown: 5 genomes with orthologs for CSW01_09720 only; 1 genomes with orthologs for CSW01_11560 only