Conservation of cofitness between CSW01_12695 and CSW01_10460 in Vibrio cholerae E7946 ATCC 55056

46 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Vibrio cholerae E7946 ATCC 55056 1.0 CSW01_12695 lactate dehydrogenase 1.0 CSW01_10460 Nif3-like dinuclear metal center hexameric protein 0.47 16
Paraburkholderia sabiae LMG 24235 0.51 QEN71_RS12185 D-2-hydroxyacid dehydrogenase 0.44 QEN71_RS27790 Nif3-like dinuclear metal center hexameric protein low > 153
Burkholderia phytofirmans PsJN 0.49 BPHYT_RS30460 glycerate dehydrogenase 0.43 BPHYT_RS17635 metal-binding protein low > 109
Castellaniella sp019104865 MT123 0.47 ABCV34_RS03645 D-2-hydroxyacid dehydrogenase 0.47 ABCV34_RS12645 Nif3-like dinuclear metal center hexameric protein low > 48
Pectobacterium carotovorum WPP14 0.46 HER17_RS12825 2-hydroxyacid dehydrogenase 0.59 HER17_RS14990 type 2 GTP cyclohydrolase I low > 75
Dechlorosoma suillum PS 0.46 Dsui_0124 lactate dehydrogenase-like oxidoreductase 0.49 Dsui_1427 dinuclear metal center protein, YbgI/SA1388 family low > 51
Paraburkholderia bryophila 376MFSha3.1 0.44 H281DRAFT_03356 glycerate dehydrogenase 0.42 H281DRAFT_05668 dinuclear metal center protein, YbgI/SA1388 family low > 103
Pseudomonas sp. BP01 0.44 JOY50_RS06325 D-2-hydroxyacid dehydrogenase 0.50 JOY50_RS15280 Nif3-like dinuclear metal center hexameric protein low > 84
Acinetobacter radioresistens SK82 0.41 MPMX26_02760 Glycerate dehydrogenase 0.45 MPMX26_00997 GTP cyclohydrolase 1 type 2 low > 36
Pantoea agglomerans CFBP13505 P0401 0.41 PagCFBP13505_RS14205 D-2-hydroxyacid dehydrogenase 0.58 PagCFBP13505_RS03495 Nif3-like dinuclear metal center hexameric protein low > 74
Pantoea sp. MT58 0.40 IAI47_20620 D-2-hydroxyacid dehydrogenase 0.57 IAI47_13810 type 2 GTP cyclohydrolase I low > 76
Marinobacter adhaerens HP15 0.40 HP15_2931 glycerate dehydrogenase 0.47 HP15_2426 NGG1p interacting factor 3, NIF3 low > 73
Pseudomonas segetis P6 0.39 ACVTMO_RS18365 2-hydroxyacid dehydrogenase 0.50 ACVTMO_RS19035 Nif3-like dinuclear metal center hexameric protein low > 75
Pseudomonas sp. S08-1 0.39 OH686_06340 D-3-phosphoglycerate dehydrogenase 0.49 OH686_08455 GTP cyclohydrolase 1 type 2-related YbgI low > 80
Pseudomonas fluorescens FW300-N2E2 0.37 Pf6N2E2_3246 D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) 0.51 Pf6N2E2_5256 FIG137478: Hypothetical protein YbgI — —
Pseudomonas sp. DMC3 0.37 GFF4454 Glycerate dehydrogenase 0.50 GFF1847 GTP cyclohydrolase 1 type 2 low > 89
Pseudomonas lactucae CFBP13502 0.37 GEMAOFIL_01109 Putative 2-hydroxyacid dehydrogenase 0.51 GEMAOFIL_00948 GTP cyclohydrolase 1 type 2 low > 96
Pseudomonas fluorescens FW300-N2C3 0.36 AO356_06935 glycerate dehydrogenase 0.50 AO356_16660 metal-binding protein low > 104
Pseudomonas fluorescens SBW25-INTG 0.36 PFLU_RS04575 2-hydroxyacid dehydrogenase 0.50 PFLU_RS03760 Nif3-like dinuclear metal center hexameric protein low > 109
Pseudomonas simiae WCS417 0.36 PS417_04530 glycerate dehydrogenase 0.50 PS417_03710 metal-binding protein low > 88
Pseudomonas orientalis W4I3 0.36 QF045_RS07500 2-hydroxyacid dehydrogenase 0.50 QF045_RS06690 Nif3-like dinuclear metal center hexameric protein low > 93
Pseudomonas fluorescens SBW25 0.36 PFLU_RS04575 2-hydroxyacid dehydrogenase 0.50 PFLU_RS03760 Nif3-like dinuclear metal center hexameric protein low > 109
Pseudomonas sp. RS175 0.35 PFR28_03622 Putative 2-hydroxyacid dehydrogenase 0.50 PFR28_00192 GTP cyclohydrolase 1 type 2 — —
Pseudomonas fluorescens FW300-N2E3 0.35 AO353_15000 glycerate dehydrogenase 0.50 AO353_05085 metal-binding protein low > 101
Shewanella loihica PV-4 0.35 Shew_0887 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding (RefSeq) 0.55 Shew_1572 hypothetical protein (RefSeq) — —
Pseudomonas sp. SVBP6 0.35 COO64_RS03380 2-hydroxyacid dehydrogenase 0.51 COO64_RS11720 Nif3-like dinuclear metal center hexameric protein low > 93
Pseudomonas stutzeri RCH2 0.35 Psest_3223 Lactate dehydrogenase and related dehydrogenases 0.50 Psest_3295 dinuclear metal center protein, YbgI/SA1388 family — —
Pseudomonas fluorescens GW456-L13 0.34 PfGW456L13_1617 D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) 0.49 PfGW456L13_4997 FIG137478: Hypothetical protein YbgI low > 87
Pseudomonas putida KT2440 0.34 PP_0762 Glycerate dehydrogenase 0.50 PP_1302 putative metal-binding hydrolase-oxidase enzyme 0.16 7
Pseudomonas aeruginosa PUPa3 0.33 DQ20_RS55745 2-hydroxyacid dehydrogenase 0.50 DQ20_RS56710 Nif3-like dinuclear metal center hexameric protein low > 101
Alteromonas macleodii MIT1002 0.33 MIT1002_04054 Putative 2-hydroxyacid dehydrogenase 0.51 MIT1002_01972 metal-binding protein low > 70
Pseudomonas aeruginosa PA14 0.33 IKLFDK_00375 2-hydroxyacid dehydrogenase 0.50 IKLFDK_01865 Nif3-like dinuclear metal center hexameric protein low > 98
Pseudomonas aeruginosa MRSN321 0.33 DY961_RS28950 2-hydroxyacid dehydrogenase 0.50 DY961_RS24250 Nif3-like dinuclear metal center hexameric protein low > 100
Shewanella oneidensis MR-1 0.32 SO3631 hprA glycerate dehydrogenase (NCBI ptt file) 0.53 SO2621 conserved hypothetical protein TIGR00486 (NCBI ptt file) low > 76
Shewanella sp. ANA-3 0.32 Shewana3_3201 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding (RefSeq) 0.53 Shewana3_1758 hypothetical protein (RefSeq) low > 73
Shewanella amazonensis SB2B 0.31 Sama_2811 glycerate dehydrogenase (RefSeq) 0.54 Sama_2050 hypothetical protein (RefSeq) low > 62
Paraburkholderia graminis OAS925 0.23 ABIE53_003066 gluconate 2-dehydrogenase 0.42 ABIE53_003686 dinuclear metal center YbgI/SA1388 family protein low > 113
Fusobacterium nucleatum SB010 0.23 HUW76_05295 3-phosphoglycerate dehydrogenase 0.13 HUW76_03660 Nif3-like dinuclear metal center hexameric protein low > 35
Dickeya dianthicola ME23 0.23 DZA65_RS00195 glyoxylate/hydroxypyruvate reductase GhrB 0.54 DZA65_RS06800 type 2 GTP cyclohydrolase I low > 75
Hydrogenophaga sp. GW460-11-11-14-LB1 0.22 GFF3835 Glyoxylate reductase (EC 1.1.1.79) / Glyoxylate reductase (EC 1.1.1.26) / Hydroxypyruvate reductase (EC 1.1.1.81); 2-ketoaldonate reductase, broad specificity (EC 1.1.1.215) (EC 1.1.1.-) 0.41 GFF1298 FIG137478: Hypothetical protein YbgI low > 90
Dickeya dianthicola 67-19 0.22 HGI48_RS00175 glyoxylate/hydroxypyruvate reductase GhrB 0.53 HGI48_RS06455 type 2 GTP cyclohydrolase I low > 71
Dickeya dadantii 3937 0.21 DDA3937_RS21080 glyoxylate/hydroxypyruvate reductase GhrB 0.56 DDA3937_RS06410 type 2 GTP cyclohydrolase I low > 74
Ralstonia solanacearum PSI07 0.21 RPSI07_RS02805 D-glycerate dehydrogenase 0.46 RPSI07_RS10495 Nif3-like dinuclear metal center hexameric protein low > 81
Variovorax sp. SCN45 0.21 GFF2715 2-ketogluconate 6-phosphate reductase (EC 1.1.1.43) 0.39 GFF5367 GTP cyclohydrolase 1 type 2 homolog YbgI low > 127
Variovorax sp. OAS795 0.21 ABID97_RS10600 D-glycerate dehydrogenase 0.36 ABID97_RS23060 Nif3-like dinuclear metal center hexameric protein low > 91
Klebsiella michiganensis M5al 0.20 BWI76_RS27925 D-isomer specific 2-hydroxyacid dehydrogenase 0.53 BWI76_RS08345 Nif3-like dinuclear metal center protein low > 92
Klebsiella pneumoniae MKP103 0.20 KDGMDA_07690 glyoxylate/hydroxypyruvate reductase GhrB 0.53 KDGMDA_16665 type 2 GTP cyclohydrolase I low > 95

Not shown: 22 genomes with orthologs for CSW01_12695 only; 32 genomes with orthologs for CSW01_10460 only