Conservation of cofitness between CSW01_07190 and CSW01_01845 in Vibrio cholerae E7946 ATCC 55056

80 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Vibrio cholerae E7946 ATCC 55056 1.0 CSW01_07190 transcriptional regulator FNR 1.0 CSW01_01845 protease modulator HflK 0.76 11
Rahnella sp. WP5 0.86 EX31_RS07200 FNR family transcription factor 0.45 EX31_RS08810 FtsH protease activity modulator HflK low > 89
Pantoea agglomerans CFBP13505 P0401 0.86 PagCFBP13505_RS06575 fumarate/nitrate reduction transcriptional regulator Fnr 0.46 PagCFBP13505_RS11195 FtsH protease activity modulator HflK low > 74
Dickeya dianthicola 67-19 0.86 HGI48_RS10900 fumarate/nitrate reduction transcriptional regulator Fnr 0.48 HGI48_RS18535 FtsH protease activity modulator HflK low > 71
Dickeya dadantii 3937 0.86 DDA3937_RS10950 fumarate/nitrate reduction transcriptional regulator Fnr 0.48 DDA3937_RS18600 FtsH protease activity modulator HflK low > 74
Dickeya dianthicola ME23 0.86 DZA65_RS11360 fumarate/nitrate reduction transcriptional regulator Fnr 0.48 DZA65_RS19670 FtsH protease activity modulator HflK low > 75
Serratia liquefaciens MT49 0.86 IAI46_13260 FNR family transcription factor 0.45 IAI46_01635 FtsH protease activity modulator HflK low > 86
Pectobacterium carotovorum WPP14 0.86 HER17_RS10525 fumarate/nitrate reduction transcriptional regulator Fnr 0.46 HER17_RS02595 FtsH protease activity modulator HflK low > 75
Pantoea sp. MT58 0.85 IAI47_09580 FNR family transcription factor 0.47 IAI47_02600 FtsH protease activity modulator HflK low > 76
Escherichia coli HS(pFamp)R (ATCC 700891) 0.85 OHPLBJKB_02348 Fumarate and nitrate reduction regulatory protein 0.48 OHPLBJKB_03868 Modulator of FtsH protease HflK low > 74
Escherichia coli ECRC100 0.85 OKFHMN_02240 fnr fumarate/nitrate reduction transcriptional regulator Fnr 0.48 OKFHMN_12245 hflK FtsH protease activity modulator HflK low > 79
Escherichia fergusonii Becca 0.85 EFB2_02593 Fumarate and nitrate reduction regulatory protein 0.49 EFB2_04361 Modulator of FtsH protease HflK low > 86
Escherichia coli BW25113 0.85 b1334 fnr DNA-binding transcriptional dual regulator, global regulator of anaerobic growth (NCBI) 0.48 b4174 hflK modulator for HflB protease specific for phage lambda cII repressor (NCBI) low > 76
Escherichia coli ECRC102 0.85 NIAGMN_26410 fnr fumarate/nitrate reduction transcriptional regulator Fnr 0.48 NIAGMN_10095 hflK FtsH protease activity modulator HflK
Escherichia coli ECOR38 0.85 HEPCGN_25925 fnr fumarate/nitrate reduction transcriptional regulator Fnr 0.49 HEPCGN_10475 hflK FtsH protease activity modulator HflK low > 88
Escherichia coli ECRC99 0.85 KEDOAH_26530 fnr fumarate/nitrate reduction transcriptional regulator Fnr 0.48 KEDOAH_15910 hflK FtsH protease activity modulator HflK
Escherichia coli Nissle 1917 0.85 ECOLIN_RS08005 fumarate/nitrate reduction transcriptional regulator Fnr 0.49 ECOLIN_RS24240 FtsH protease activity modulator HflK low > 55
Escherichia coli ECRC62 0.85 BNILDI_18090 fnr fumarate/nitrate reduction transcriptional regulator Fnr 0.48 BNILDI_06980 hflK FtsH protease activity modulator HflK low > 75
Escherichia coli ECRC101 0.85 MCAODC_16030 fnr fumarate/nitrate reduction transcriptional regulator Fnr 0.48 MCAODC_02760 hflK FtsH protease activity modulator HflK low > 88
Escherichia coli ECOR27 0.85 NOLOHH_19940 fnr fumarate/nitrate reduction transcriptional regulator Fnr 0.48 NOLOHH_04510 hflK FtsH protease activity modulator HflK low > 76
Escherichia coli ECRC98 0.85 JDDGAC_04785 fnr fumarate/nitrate reduction transcriptional regulator Fnr 0.48 JDDGAC_15885 hflK FtsH protease activity modulator HflK low > 87
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.85 GFF2656 Fumarate and nitrate reduction regulatory protein 0.48 GFF827 HflK protein low > 78
Klebsiella michiganensis M5al 0.85 BWI76_RS16185 transcriptional regulator FNR 0.45 BWI76_RS02545 protease modulator HflK
Klebsiella pneumoniae MKP103 0.85 KDGMDA_21005 fumarate/nitrate reduction transcriptional regulator Fnr 0.48 KDGMDA_11045 FtsH protease activity modulator HflK low > 95
Enterobacter sp. TBS_079 0.85 MPMX20_02035 Fumarate and nitrate reduction regulatory protein 0.46 MPMX20_00455 Modulator of FtsH protease HflK low > 85
Enterobacter asburiae PDN3 0.84 EX28DRAFT_1540 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases 0.48 EX28DRAFT_3371 HflK protein low > 76
Erwinia tracheiphila SCR3 0.83 LU632_RS11420 FNR family transcription factor 0.46 LU632_RS02065 hflK FtsH protease activity modulator HflK low > 74
Erwinia tracheiphila HP pepo 2.2 0.83 IJEDHG_23150 crp transcriptional regulator FNR 0.46 IJEDHG_06855 hflK FtsH protease activity modulator HflK
Erwinia amylovora T8 0.83 OLJFJH_13925 transcriptional regulator FNR 0.44 OLJFJH_02490 FtsH protease activity modulator HflK low > 58
Shewanella sp. ANA-3 0.77 Shewana3_2115 fumarate/nitrate reduction transcriptional regulator (RefSeq) 0.51 Shewana3_0599 HflK protein (RefSeq)
Shewanella oneidensis MR-1 0.76 SO2356 etrA electron transport regulator a (NCBI ptt file) 0.50 SO0605 hflK hflK protein (NCBI ptt file) low > 76
Shewanella amazonensis SB2B 0.76 Sama_1799 fumarate/nitrate reduction transcriptional regulator (RefSeq) 0.47 Sama_3023 hflK protein (RefSeq) low > 62
Shewanella loihica PV-4 0.76 Shew_1993 fumarate/nitrate reduction transcriptional regulator (RefSeq) 0.50 Shew_0568 HflK protein (RefSeq)
Alteromonas macleodii MIT1002 0.57 MIT1002_02137 Fumarate and nitrate reduction regulatory protein 0.48 MIT1002_03786 Modulator of FtsH protease HflK low > 70
Kangiella aquimarina DSM 16071 0.56 B158DRAFT_1982 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases 0.31 B158DRAFT_1954 protease FtsH subunit HflK low > 40
Pseudomonas segetis P6 0.54 MPMX49_02303 Transcriptional activator protein Anr 0.36 MPMX49_04151 Modulator of FtsH protease HflK 0.65 11
Pseudomonas syringae pv. syringae B728a ΔmexB 0.54 Psyr_3425 Cyclic nucleotide-binding:Bacterial regulatory protein, Crp 0.35 Psyr_0574 protease FtsH subunit HflK
Pseudomonas syringae pv. syringae B728a 0.54 Psyr_3425 Cyclic nucleotide-binding:Bacterial regulatory protein, Crp 0.35 Psyr_0574 protease FtsH subunit HflK low > 86
Pseudomonas sp. DMC3 0.54 GFF711 Transcriptional activator protein Anr 0.35 GFF3222 Modulator of FtsH protease HflK
Pseudomonas fluorescens GW456-L13 0.54 PfGW456L13_4071 Fumarate and nitrate reduction regulatory protein 0.35 PfGW456L13_152 HflK protein low > 87
Pseudomonas simiae WCS417 0.53 PS417_20785 transcriptional regulator 0.35 PS417_02500 membrane protein
Pseudomonas sp. RS175 0.53 PFR28_01079 Transcriptional activator protein Anr 0.36 PFR28_05123 Modulator of FtsH protease HflK
Pseudomonas fluorescens SBW25 0.53 PFLU_RS22395 fumarate/nitrate reduction transcriptional regulator Fnr 0.36 PFLU_RS02580 FtsH protease activity modulator HflK low > 109
Pseudomonas fluorescens FW300-N1B4 0.53 Pf1N1B4_3867 Fumarate and nitrate reduction regulatory protein 0.37 Pf1N1B4_1410 HflK protein
Pseudomonas lactucae CFBP13502 0.53 GEMAOFIL_04302 Transcriptional activator protein Anr 0.35 GEMAOFIL_00738 Modulator of FtsH protease HflK
Pseudomonas fluorescens SBW25-INTG 0.53 PFLU_RS22395 fumarate/nitrate reduction transcriptional regulator Fnr 0.36 PFLU_RS02580 FtsH protease activity modulator HflK low > 109
Pseudomonas aeruginosa PA14 0.53 IKLFDK_07375 transcriptional regulator Anr 0.36 IKLFDK_28830 FtsH protease activity modulator HflK
Pseudomonas fluorescens FW300-N2E3 0.53 AO353_00660 transcriptional regulator 0.36 AO353_13155 hypothetical protein low > 101
Pseudomonas fluorescens FW300-N2E2 0.53 Pf6N2E2_2323 Fumarate and nitrate reduction regulatory protein 0.35 Pf6N2E2_3612 HflK protein low > 103
Pseudomonas sp. S08-1 0.53 OH686_02245 Fumarate and nitrate reduction regulatory protein 0.34 OH686_09460 HflK protein low > 80
Pseudomonas fluorescens FW300-N2C3 0.53 AO356_02485 transcriptional regulator 0.36 AO356_08645 hypothetical protein low > 104
Pseudomonas stutzeri RCH2 0.53 Psest_2538 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases 0.34 Psest_0685 HflK protein
Pseudomonas sp. SVBP6 0.52 COO64_RS18640 fnrA Crp/Fnr family transcriptional regulator FnrA 0.34 COO64_RS17910 hflK FtsH protease activity modulator HflK low > 93
Pseudomonas putida KT2440 0.52 PP_4265 DNA-binding transcriptional dual regulator 0.34 PP_4892 integral membrane ATP-dependent zinc metallopeptidase / HflK-HflC complex low > 96
Pseudomonas sp. BP01 0.52 JOY50_RS00125 fnrA Crp/Fnr family transcriptional regulator FnrA 0.34 JOY50_RS17240 hflK FtsH protease activity modulator HflK low > 84
Herbaspirillum seropedicae SmR1 0.41 HSERO_RS16020 transcriptional regulator 0.31 HSERO_RS14765 membrane protein
Marinobacter adhaerens HP15 0.41 HP15_634 transcriptional regulator, Crp/Fnr family 0.37 HP15_2497 HflK low > 73
Dechlorosoma suillum PS 0.40 Dsui_1646 cAMP-binding protein 0.35 Dsui_3135 HflK protein
Cupriavidus basilensis FW507-4G11 0.40 RR42_RS12875 transcriptional regulator 0.32 RR42_RS13105 membrane protein
Hydrogenophaga sp. GW460-11-11-14-LB1 0.39 GFF4142 transcriptional regulator, Crp/Fnr family 0.33 GFF4856 HflK protein low > 90
Ralstonia sp. UNC404CL21Col 0.39 ABZR87_RS11180 fumarate/nitrate reduction transcriptional regulator Fnr 0.32 ABZR87_RS10950 FtsH protease activity modulator HflK low > 80
Methylophilus sp. DMC18 0.38 GFF1089 Transcriptional activator protein Anr 0.32 GFF1223 hypothetical protein low > 43
Ralstonia solanacearum IBSBF1503 0.38 RALBFv3_RS15650 fumarate/nitrate reduction transcriptional regulator Fnr 0.33 RALBFv3_RS15310 FtsH protease activity modulator HflK low > 76
Ralstonia solanacearum UW163 0.38 UW163_RS13110 fumarate/nitrate reduction transcriptional regulator Fnr 0.33 UW163_RS12775 FtsH protease activity modulator HflK
Ralstonia solanacearum PSI07 0.38 RPSI07_RS17705 fumarate/nitrate reduction transcriptional regulator Fnr 0.34 RPSI07_RS18065 FtsH protease activity modulator HflK low > 81
Acidovorax sp. GW101-3H11 0.38 Ac3H11_975 transcriptional regulator, Crp/Fnr family 0.31 Ac3H11_1801 HflK protein
Ralstonia solanacearum GMI1000 0.38 RS_RS06430 fumarate/nitrate reduction transcriptional regulator Fnr 0.31 RS_RS06120 FtsH protease activity modulator HflK low > 80
Lysobacter sp. OAE881 0.37 ABIE51_RS03805 fumarate/nitrate reduction transcriptional regulator Fnr 0.24 ABIE51_RS06550 FtsH protease activity modulator HflK low > 62
Rhodanobacter sp. FW510-T8 0.37 OKGIIK_00820 CRP-like protein Clp 0.29 OKGIIK_06640 hflK FtsH protease activity modulator HflK low > 53
Rhodanobacter sp000427505 FW510-R12 0.35 LRK53_RS14515 cyclic nucleotide-binding domain-containing protein 0.28 LRK53_RS09535 FtsH protease activity modulator HflK low > 59
Rhodanobacter denitrificans FW104-10B01 0.35 LRK54_RS05830 helix-turn-helix domain-containing protein 0.28 LRK54_RS00620 FtsH protease activity modulator HflK low > 59
Rhodanobacter denitrificans MT42 0.35 LRK55_RS05585 helix-turn-helix domain-containing protein 0.28 LRK55_RS00390 FtsH protease activity modulator HflK low > 63
Castellaniella sp019104865 MT123 0.34 ABCV34_RS06835 helix-turn-helix domain-containing protein 0.33 ABCV34_RS02660 FtsH protease activity modulator HflK
Azospirillum sp. SherDot2 0.26 MPMX19_00212 Nitrogen fixation regulation protein FixK 0.23 MPMX19_01251 Modulator of FtsH protease HflK
Dyella japonica UNC79MFTsu3.2 0.25 ABZR86_RS04345 cyclic nucleotide-binding domain-containing protein 0.27 ABZR86_RS08355 FtsH protease activity modulator HflK low > 74
Xanthomonas campestris pv. campestris strain 8004 0.22 Xcc-8004.2952.1 transcriptional regulator, Crp/Fnr family 0.25 Xcc-8004.3955.1 HflK protein low > 74
Variovorax sp. SCN45 0.22 GFF6947 transcriptional regulator, Crp/Fnr family 0.33 GFF1002 HflK protein low > 127
Magnetospirillum magneticum AMB-1 0.22 AMB_RS22105 transcriptional regulator 0.25 AMB_RS17650 FtsH protease activity modulator HflK
Rhodospirillum rubrum S1H 0.22 Rru_A3322 Transcriptional Regulator, Crp/Fnr family (NCBI) 0.26 Rru_A2203 HflK (NCBI)
Agrobacterium fabrum C58 0.19 Atu1602 transcriptional activator, Crp family 0.22 Atu2045 HFLK protein low > 89
Dinoroseobacter shibae DFL-12 0.15 Dshi_0660 transcriptional regulator, Crp/Fnr family (RefSeq) 0.25 Dshi_2736 HflK protein (RefSeq) low > 64

Not shown: 12 genomes with orthologs for CSW01_07190 only; 6 genomes with orthologs for CSW01_01845 only