| Organism | Ratio1 | Gene1 | Name1 | Description1 | Ratio2 | Gene2 | Name2 | Description2 | Cofit | Rank |
| Vibrio cholerae E7946 ATCC 55056 | 1.0 | CSW01_07255 | | HlyD family type I secretion periplasmic adaptor subunit | 1.0 | CSW01_01485 | | transcriptional regulator | 0.71 | 9 |
| Pseudomonas syringae pv. syringae B728a ΔmexB | 0.30 | Psyr_3075 | | Type I secretion membrane fusion protein, HlyD | 0.32 | Psyr_3336 | | transcriptional regulator, LacI family | low | > 86 |
| Pseudomonas syringae pv. syringae B728a | 0.30 | Psyr_3075 | | Type I secretion membrane fusion protein, HlyD | 0.32 | Psyr_3336 | | transcriptional regulator, LacI family | low | > 86 |
| Hydrogenophaga sp. GW460-11-11-14-LB1 | 0.27 | GFF1395 | | HlyD family secretion protein | 0.30 | GFF5509 | | Gluconate utilization system Gnt-I transcriptional repressor | low | > 90 |
| Pseudomonas putida KT2440 | 0.26 | PP_4926 | | HlyD family secretion protein | 0.31 | PP_3415 | | Transcriptional regulator, LacI family | low | > 96 |
| Variovorax sp. SCN45 | 0.26 | GFF1931 | | RTX toxin transporter, determinant D | 0.30 | GFF7257 | | KEGG: LacI family transcriptional regulator, gluconate utilization system Gnt-I transcriptional repressor | low | > 127 |
| Escherichia coli ECRC98 | 0.24 | JDDGAC_29910 | ehxD | enterohemolysin T1SS ABC transporter subunit EhxD | 0.52 | JDDGAC_20465 | gntR | gluconate operon transcriptional repressor GntR | low | > 87 |
| Escherichia coli ECRC101 | 0.24 | MCAODC_15350 | ehxD | enterohemolysin T1SS ABC transporter subunit EhxD | 0.52 | MCAODC_07365 | gntR | gluconate operon transcriptional repressor GntR | low | > 88 |
| Escherichia coli ECRC102 | 0.24 | NIAGMN_28520 | ehxD | enterohemolysin T1SS ABC transporter subunit EhxD | 0.52 | NIAGMN_14605 | gntR | gluconate operon transcriptional repressor GntR | low | > 80 |
| Escherichia coli ECRC100 | 0.24 | OKFHMN_00200 | ehxD | enterohemolysin T1SS ABC transporter subunit EhxD | 0.52 | OKFHMN_16835 | gntR | gluconate operon transcriptional repressor GntR | low | > 79 |
| Escherichia fergusonii Becca | 0.24 | EFB2_00100 | | Hemolysin secretion protein D, chromosomal | 0.52 | EFB2_00382 | | HTH-type transcriptional regulator GntR | low | > 86 |
| Azospirillum sp. SherDot2 | 0.23 | MPMX19_05207 | | Hemolysin secretion protein D, plasmid | 0.29 | MPMX19_05332 | | HTH-type transcriptional regulator GntR | low | > 112 |
| Ralstonia solanacearum PSI07 | 0.22 | RPSI07_RS01225 | | HlyD family type I secretion periplasmic adaptor subunit | 0.26 | RPSI07_RS07575 | | LacI family DNA-binding transcriptional regulator | low | > 81 |
| Ralstonia solanacearum GMI1000 | 0.22 | RS_RS18560 | | HlyD family type I secretion periplasmic adaptor subunit | 0.26 | RS_RS24865 | | LacI family DNA-binding transcriptional regulator | low | > 80 |
| Ralstonia solanacearum IBSBF1503 | 0.22 | RALBFv3_RS20765 | | HlyD family type I secretion periplasmic adaptor subunit | 0.24 | RALBFv3_RS16125 | | GntR family transcriptional regulator | 0.38 | 3 |
| Ralstonia solanacearum UW163 | 0.22 | UW163_RS22520 | | HlyD family type I secretion periplasmic adaptor subunit | 0.24 | UW163_RS16860 | | GntR family transcriptional regulator | — | — |
| Herbaspirillum seropedicae SmR1 | 0.21 | HSERO_RS14450 | | membrane protein | 0.34 | HSERO_RS05460 | | LacI family transcription regulator | low | > 78 |
| Sinorhizobium meliloti 1021 | 0.17 | SMc02571 | | toxin secretion transmembrane protein | 0.29 | SM_b20667 | | LacI family transcriptional regulator | low | > 103 |
| Azospirillum brasilense Sp245 | 0.12 | AZOBR_RS33440 | | secretion protein | 0.31 | AZOBR_RS15720 | | LacI family transcription regulator | — | — |
| Paraburkholderia bryophila 376MFSha3.1 | 0.10 | H281DRAFT_03780 | | HlyD family secretion protein | 0.30 | H281DRAFT_05920 | | transcriptional regulator, LacI family | low | > 103 |
| Paraburkholderia sabiae LMG 24235 | 0.10 | QEN71_RS14530 | | HlyD family efflux transporter periplasmic adaptor subunit | 0.29 | QEN71_RS13585 | | LacI family DNA-binding transcriptional regulator | low | > 153 |
| Alteromonas macleodii MIT1002 | 0.09 | MIT1002_03652 | | Colicin V secretion protein CvaA | 0.31 | MIT1002_03475 | | Gluconate utilization system GNT-I transcriptional repressor | low | > 70 |
| Erwinia tracheiphila HP pepo 2.2 | 0.08 | IJEDHG_11755 | | Anibiotic ABC transporter | 0.54 | IJEDHG_08040 | gntR | gluconate operon transcriptional repressor GntR | low | > 61 |
| Erwinia tracheiphila SCR3 | 0.08 | LU632_RS23120 | | HlyD family efflux transporter periplasmic adaptor subunit | 0.53 | LU632_RS19160 | gntR | gluconate operon transcriptional repressor GntR | low | > 74 |
| Klebsiella pneumoniae MKP103 | 0.06 | KDGMDA_10860 | | HlyD family secretion protein | 0.51 | KDGMDA_07120 | | gluconate operon transcriptional repressor GntR | low | > 95 |
Not shown: 5 genomes with orthologs for CSW01_07255 only; 48 genomes with orthologs for CSW01_01485 only