Conservation of cofitness between CSW01_01000 and CSW01_01485 in Vibrio cholerae E7946 ATCC 55056

67 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Vibrio cholerae E7946 ATCC 55056 1.0 CSW01_01000 glutathione-disulfide reductase 1.0 CSW01_01485 transcriptional regulator 0.71 12
Serratia liquefaciens MT49 0.75 IAI46_24240 glutathione-disulfide reductase 0.54 IAI46_23965 gluconate operon transcriptional repressor GntR 0.96 30
Klebsiella michiganensis M5al 0.75 BWI76_RS26685 glutathione-disulfide reductase 0.51 BWI76_RS26245 transcriptional regulator low > 92
Klebsiella pneumoniae MKP103 0.75 KDGMDA_07440 glutathione-disulfide reductase 0.51 KDGMDA_07120 gluconate operon transcriptional repressor GntR 0.65 63
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.74 GFF513 Glutathione reductase (EC 1.8.1.7) 0.49 GFF570 Gluconate utilization system Gnt-I transcriptional repressor low > 78
Erwinia tracheiphila HP pepo 2.2 0.74 IJEDHG_12565 gorA glutathione-disulfide reductase 0.54 IJEDHG_08040 gntR gluconate operon transcriptional repressor GntR — —
Erwinia tracheiphila SCR3 0.74 LU632_RS19495 gorA glutathione-disulfide reductase 0.53 LU632_RS19160 gntR gluconate operon transcriptional repressor GntR low > 73
Pantoea sp. MT58 0.74 IAI47_01325 glutathione-disulfide reductase 0.52 IAI47_01650 gluconate operon transcriptional repressor GntR 0.42 60
Pantoea agglomerans CFBP13505 P0401 0.74 PagCFBP13505_RS17825 glutathione-disulfide reductase 0.50 PagCFBP13505_RS18155 gluconate operon transcriptional repressor GntR low > 74
Pectobacterium carotovorum WPP14 0.73 HER17_RS21240 glutathione-disulfide reductase 0.52 HER17_RS01450 gluconate operon transcriptional repressor GntR low > 75
Rahnella sp. WP5 0.73 EX31_RS05175 glutathione-disulfide reductase 0.54 EX31_RS05060 gluconate operon transcriptional repressor GntR low > 89
Erwinia amylovora T8 0.73 OLJFJH_04565 Glutathione oxidoreductase 0.56 OLJFJH_04280 gluconate operon transcriptional repressor GntR low > 58
Escherichia coli ECRC99 0.73 KEDOAH_11740 gorA glutathione-disulfide reductase 0.52 KEDOAH_11305 gntR gluconate operon transcriptional repressor GntR — —
Escherichia coli ECRC102 0.73 NIAGMN_14170 gorA glutathione-disulfide reductase 0.52 NIAGMN_14605 gntR gluconate operon transcriptional repressor GntR low > 80
Escherichia coli ECRC100 0.73 OKFHMN_16405 gorA glutathione-disulfide reductase 0.52 OKFHMN_16835 gntR gluconate operon transcriptional repressor GntR low > 79
Escherichia fergusonii Becca 0.73 EFB2_00315 Glutathione reductase 0.52 EFB2_00382 HTH-type transcriptional regulator GntR low > 86
Escherichia coli ECRC98 0.73 JDDGAC_20035 gorA glutathione-disulfide reductase 0.52 JDDGAC_20465 gntR gluconate operon transcriptional repressor GntR 0.49 60
Escherichia coli Nissle 1917 0.73 ECOLIN_RS19995 glutathione-disulfide reductase 0.52 ECOLIN_RS19675 gluconate operon transcriptional repressor GntR low > 55
Escherichia coli ECRC101 0.73 MCAODC_06920 gorA glutathione-disulfide reductase 0.52 MCAODC_07365 gntR gluconate operon transcriptional repressor GntR 0.48 81
Escherichia coli ECOR38 0.73 HEPCGN_15315 gorA glutathione-disulfide reductase 0.52 HEPCGN_15660 gntR gluconate operon transcriptional repressor GntR low > 88
Enterobacter sp. TBS_079 0.73 MPMX20_04399 Glutathione reductase 0.52 MPMX20_04319 HTH-type transcriptional regulator GntR low > 85
Escherichia coli HS(pFamp)R (ATCC 700891) 0.72 OHPLBJKB_00203 Glutathione reductase 0.52 OHPLBJKB_00264 HTH-type transcriptional regulator GntR low > 74
Escherichia coli BL21 0.72 ECD_03349 glutathione oxidoreductase 0.51 ECD_03289 d-gluconate inducible gluconate regulon transcriptional repressor low > 61
Escherichia coli ECOR27 0.72 NOLOHH_08340 gorA glutathione-disulfide reductase 0.51 NOLOHH_08635 gntR gluconate operon transcriptional repressor GntR low > 76
Escherichia coli ECRC62 0.72 BNILDI_03220 gorA glutathione-disulfide reductase 0.52 BNILDI_02870 gntR gluconate operon transcriptional repressor GntR 0.66 75
Dickeya dadantii 3937 0.72 DDA3937_RS21245 glutathione-disulfide reductase 0.55 DDA3937_RS19785 gluconate operon transcriptional repressor GntR low > 74
Escherichia coli BW25113 0.72 b3500 gor glutathione reductase (NCBI) 0.52 b3438 gntR DNA-binding transcriptional repressor (NCBI) low > 76
Enterobacter asburiae PDN3 0.72 EX28DRAFT_4061 NADPH-glutathione reductase (EC 1.8.1.7) 0.51 EX28DRAFT_4274 transcriptional regulator, LacI family low > 76
Dickeya dianthicola ME23 0.72 DZA65_RS00055 glutathione-disulfide reductase 0.55 DZA65_RS20970 gluconate operon transcriptional repressor GntR low > 75
Dickeya dianthicola 67-19 0.71 HGI48_RS00065 glutathione-disulfide reductase 0.55 HGI48_RS19900 gluconate operon transcriptional repressor GntR low > 71
Alteromonas macleodii MIT1002 0.66 MIT1002_03638 Glutathione reductase 0.31 MIT1002_03475 Gluconate utilization system GNT-I transcriptional repressor low > 70
Pseudomonas segetis P6 0.40 ACVTMO_RS12455 gorA glutathione-disulfide reductase 0.33 ACVTMO_RS11810 gntR HTH-type transcriptional regulator GntR low > 75
Pseudomonas fluorescens FW300-N2E3 0.39 AO353_24480 glutathione reductase 0.33 AO353_03255 LacI family transcriptional regulator low > 101
Pseudomonas sp. BP01 0.39 JOY50_RS04120 gorA glutathione-disulfide reductase 0.31 JOY50_RS23605 LacI family DNA-binding transcriptional regulator low > 84
Pseudomonas putida KT2440 0.39 PP_3819 glutathione reductase (NADPH) 0.31 PP_3415 Transcriptional regulator, LacI family low > 96
Pseudomonas sp. SVBP6 0.38 COO64_RS22975 gorA glutathione-disulfide reductase 0.34 COO64_RS25590 LacI family DNA-binding transcriptional regulator low > 93
Pseudomonas aeruginosa PA14 0.38 IKLFDK_09905 glutathione-disulfide reductase 0.36 IKLFDK_11375 LacI family DNA-binding transcriptional regulator GntR low > 98
Pseudomonas lactucae CFBP13502 0.38 GEMAOFIL_02927 Glutathione reductase 0.34 GEMAOFIL_04536 HTH-type transcriptional regulator GntR low > 96
Pseudomonas aeruginosa MRSN321 0.38 DY961_RS16315 gorA;go_function=glutathione-disulfide glutathione-disulfide reductase 0.36 DY961_RS17990 gntR;inference=COORDINATES LacI family DNA-binding transcriptional regulator GntR low > 100
Pseudomonas orientalis W4I3 0.38 QF045_RS15900 glutathione-disulfide reductase 0.34 QF045_RS24095 LacI family DNA-binding transcriptional regulator low > 93
Pseudomonas fluorescens GW456-L13 0.38 PfGW456L13_2924 Glutathione reductase (EC 1.8.1.7) 0.34 PfGW456L13_1925 Gluconate utilization system Gnt-I transcriptional repressor low > 87
Pseudomonas simiae WCS417 0.38 PS417_14060 glutathione reductase 0.33 PS417_21990 LacI family transcriptional regulator — —
Pseudomonas aeruginosa PUPa3 0.38 DQ20_RS38635 gorA;go_function=glutathione-disulfide glutathione-disulfide reductase 0.36 DQ20_RS59230 gntR;inference=COORDINATES LacI family DNA-binding transcriptional regulator GntR low > 101
Pseudomonas fluorescens FW300-N2C3 0.38 AO356_22800 glutathione reductase 0.34 AO356_05065 LacI family transcriptional regulator low > 104
Pseudomonas fluorescens SBW25-INTG 0.38 PFLU_RS14555 glutathione-disulfide reductase 0.34 PFLU_RS23595 LacI family DNA-binding transcriptional regulator low > 109
Pseudomonas fluorescens SBW25 0.38 PFLU_RS14555 glutathione-disulfide reductase 0.34 PFLU_RS23595 LacI family DNA-binding transcriptional regulator low > 109
Pseudomonas fluorescens FW300-N2E2 0.38 Pf6N2E2_446 Glutathione reductase (EC 1.8.1.7) 0.34 Pf6N2E2_2865 Gluconate utilization system Gnt-I transcriptional repressor low > 103
Pseudomonas fluorescens FW300-N1B4 0.38 Pf1N1B4_5014 Glutathione reductase (EC 1.8.1.7) 0.35 Pf1N1B4_558 Gluconate utilization system Gnt-I transcriptional repressor low > 87
Pseudomonas sp. RS175 0.37 PFR28_02483 Glutathione reductase 0.34 PFR28_00593 HTH-type transcriptional regulator GntR low > 88
Pseudomonas sp. DMC3 0.37 GFF2944 Glutathione amide reductase 0.33 GFF5268 HTH-type transcriptional regulator GntR low > 89
Variovorax sp. SCN45 0.37 GFF3591 Glutathione reductase (EC 1.8.1.7) 0.30 GFF7257 KEGG: LacI family transcriptional regulator, gluconate utilization system Gnt-I transcriptional repressor low > 127
Pseudomonas syringae pv. syringae B728a 0.37 Psyr_2979 NADPH-glutathione reductase 0.32 Psyr_3336 transcriptional regulator, LacI family low > 86
Pseudomonas stutzeri RCH2 0.37 Psest_2230 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes 0.34 Psest_2126 Transcriptional regulators low > 67
Pseudomonas syringae pv. syringae B728a ΔmexB 0.37 Psyr_2979 NADPH-glutathione reductase 0.32 Psyr_3336 transcriptional regulator, LacI family low > 86
Azospirillum brasilense Sp245 0.36 AZOBR_RS09745 glutathione reductase 0.31 AZOBR_RS15720 LacI family transcription regulator — —
Variovorax sp. OAS795 0.36 ABID97_RS00865 glutathione-disulfide reductase 0.29 ABID97_RS01205 LacI family DNA-binding transcriptional regulator low > 91
Azospirillum sp. SherDot2 0.36 MPMX19_04368 Glutathione amide reductase 0.29 MPMX19_05332 HTH-type transcriptional regulator GntR low > 112
Herbaspirillum seropedicae SmR1 0.35 HSERO_RS16580 glutathione reductase 0.34 HSERO_RS05460 LacI family transcription regulator low > 78
Hydrogenophaga sp. GW460-11-11-14-LB1 0.34 GFF372 Glutathione reductase (EC 1.8.1.7) 0.30 GFF5509 Gluconate utilization system Gnt-I transcriptional repressor low > 90
Phaeobacter inhibens DSM 17395 0.32 PGA1_c23720 glutathione reductase Gor 0.28 PGA1_c33870 putative HTH-type transcriptional regulator GntR low > 62
Dinoroseobacter shibae DFL-12 0.31 Dshi_2737 pyridine nucleotide-disulphide oxidoreductase dimerisation region (RefSeq) 0.27 Dshi_3322 transcriptional regulator, LacI family (RefSeq) low > 64
Agrobacterium fabrum C58 0.30 Atu1611 glutathione reductase 0.28 Atu4685 LacI family transcriptional regulator — —
Rhizobium sp. OAE497 0.30 ABIE40_RS10515 glutathione-disulfide reductase 0.25 ABIE40_RS04445 LacI family DNA-binding transcriptional regulator low > 107
Xanthobacter sp. DMC5 0.29 GFF3063 Glutathione amide reductase 0.31 GFF1533 HTH-type transcriptional regulator GntR — —
Sinorhizobium meliloti 1021 0.29 SMc00154 glutathione reductase 0.29 SM_b20667 LacI family transcriptional regulator — —
Cupriavidus basilensis FW507-4G11 0.25 RR42_RS20585 pyridine nucleotide-disulfide oxidoreductase 0.26 RR42_RS22645 GntR family transcriptional regulator low > 128
Ralstonia sp. UNC404CL21Col 0.21 ABZR87_RS05295 NAD(P)/FAD-dependent oxidoreductase 0.26 ABZR87_RS18255 LacI family DNA-binding transcriptional regulator low > 80
Ralstonia solanacearum PSI07 0.21 RPSI07_RS23885 NAD(P)/FAD-dependent oxidoreductase 0.26 RPSI07_RS07575 LacI family DNA-binding transcriptional regulator low > 81

Not shown: 25 genomes with orthologs for CSW01_01000 only; 8 genomes with orthologs for CSW01_01485 only