Conservation of cofitness between BWI76_RS04170 and BWI76_RS02550 in Klebsiella michiganensis M5al

29 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Klebsiella michiganensis M5al 1.0 BWI76_RS04170 trifunctional nicotinamide-nucleotide adenylyltransferase/ribosylnicotinamide kinase/transcriptional regulator NadR 1.0 BWI76_RS02550 protease modulator HflC 0.49 4
Klebsiella pneumoniae MKP103 0.97 KDGMDA_12440 multifunctional transcriptional regulator/nicotinamide-nucleotide adenylyltransferase/ribosylnicotinamide kinase NadR 0.91 KDGMDA_11050 protease modulator HflC low > 95
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.94 GFF1058 NadR transcriptional regulator / Nicotinamide-nucleotide adenylyltransferase, NadR family (EC 2.7.7.1) / Ribosylnicotinamide kinase (EC 2.7.1.22) 0.88 GFF828 HflC protein low > 78
Enterobacter asburiae PDN3 0.94 EX28DRAFT_3598 nicotinamide-nucleotide adenylyltransferase, NadR type 0.85 EX28DRAFT_3372 HflC protein low > 76
Enterobacter sp. TBS_079 0.93 MPMX20_00695 Trifunctional NAD biosynthesis/regulator protein NadR 0.88 MPMX20_00456 Modulator of FtsH protease HflC low > 85
Escherichia coli BW25113 0.92 b4390 nadR probable nadAB transcriptional regulator (VIMSS) 0.88 b4175 hflC modulator for HflB protease specific for phage lambda cII repressor (NCBI) 0.33 3
Escherichia coli ECOR38 0.92 HEPCGN_09190 nadR multifunctional transcriptional regulator/nicotinamide-nucleotide adenylyltransferase/ribosylnicotinamide kinase NadR 0.88 HEPCGN_10470 hflC protease modulator HflC low > 88
Escherichia coli Nissle 1917 0.92 ECOLIN_RS25195 multifunctional transcriptional regulator/nicotinamide-nucleotide adenylyltransferase/ribosylnicotinamide kinase NadR 0.88 ECOLIN_RS24245 protease modulator HflC — —
Escherichia coli ECRC99 0.92 KEDOAH_16965 nadR multifunctional transcriptional regulator/nicotinamide-nucleotide adenylyltransferase/ribosylnicotinamide kinase NadR 0.88 KEDOAH_15915 hflC protease modulator HflC — —
Escherichia coli ECRC102 0.92 NIAGMN_09040 nadR multifunctional transcriptional regulator/nicotinamide-nucleotide adenylyltransferase/ribosylnicotinamide kinase NadR 0.88 NIAGMN_10090 hflC protease modulator HflC low > 80
Escherichia coli ECRC98 0.92 JDDGAC_14785 nadR multifunctional transcriptional regulator/nicotinamide-nucleotide adenylyltransferase/ribosylnicotinamide kinase NadR 0.88 JDDGAC_15880 hflC protease modulator HflC low > 87
Escherichia coli ECRC101 0.92 MCAODC_01705 nadR multifunctional transcriptional regulator/nicotinamide-nucleotide adenylyltransferase/ribosylnicotinamide kinase NadR 0.88 MCAODC_02755 hflC protease modulator HflC low > 88
Escherichia coli ECRC100 0.92 OKFHMN_11190 nadR multifunctional transcriptional regulator/nicotinamide-nucleotide adenylyltransferase/ribosylnicotinamide kinase NadR 0.88 OKFHMN_12240 hflC protease modulator HflC low > 79
Escherichia coli ECRC62 0.92 BNILDI_08080 nadR multifunctional transcriptional regulator/nicotinamide-nucleotide adenylyltransferase/ribosylnicotinamide kinase NadR 0.88 BNILDI_06985 hflC protease modulator HflC low > 75
Escherichia coli HS(pFamp)R (ATCC 700891) 0.92 OHPLBJKB_03671 Trifunctional NAD biosynthesis/regulator protein NadR 0.88 OHPLBJKB_03867 Modulator of FtsH protease HflC low > 74
Escherichia coli ECOR27 0.92 NOLOHH_03515 nadR multifunctional transcriptional regulator/nicotinamide-nucleotide adenylyltransferase/ribosylnicotinamide kinase NadR 0.88 NOLOHH_04505 hflC protease modulator HflC low > 76
Escherichia fergusonii Becca 0.92 EFB2_04056 Trifunctional NAD biosynthesis/regulator protein NadR 0.88 EFB2_04360 Modulator of FtsH protease HflC low > 86
Escherichia coli BL21 0.92 ECD_04266 trifunctional protein: nicotinamide mononucleotide adenylyltransferase, ribosylnicotinamide kinase, transcriptional repressor 0.88 ECD_04042 HflB protease modulator specific for phage lambda cII repressor low > 61
Pantoea sp. MT58 0.89 IAI47_16340 multifunctional transcriptional regulator/nicotinamide-nucleotide adenylyltransferase/ribosylnicotinamide kinase NadR 0.81 IAI47_02605 protease modulator HflC 0.56 7
Pantoea agglomerans CFBP13505 P0401 0.89 PagCFBP13505_RS21760 multifunctional transcriptional regulator/nicotinamide-nucleotide adenylyltransferase/ribosylnicotinamide kinase NadR 0.80 PagCFBP13505_RS11200 protease modulator HflC low > 74
Rahnella sp. WP5 0.88 EX31_RS04025 multifunctional transcriptional regulator/nicotinamide-nucleotide adenylyltransferase/ribosylnicotinamide kinase NadR 0.79 EX31_RS08805 protease modulator HflC low > 89
Erwinia tracheiphila HP pepo 2.2 0.88 IJEDHG_06360 nadR multifunctional transcriptional regulator/nicotinamide-nucleotide adenylyltransferase/ribosylnicotinamide kinase NadR 0.84 IJEDHG_06850 hflC protease modulator HflC low > 61
Erwinia tracheiphila SCR3 0.88 LU632_RS02555 nadR multifunctional transcriptional regulator/nicotinamide-nucleotide adenylyltransferase/ribosylnicotinamide kinase NadR 0.82 LU632_RS02070 hflC protease modulator HflC low > 74
Dickeya dadantii 3937 0.88 DDA3937_RS02415 multifunctional transcriptional regulator/nicotinamide-nucleotide adenylyltransferase/ribosylnicotinamide kinase NadR 0.75 DDA3937_RS18595 protease modulator HflC — —
Erwinia amylovora T8 0.87 OLJFJH_01585 multifunctional transcriptional regulator/nicotinamide-nucleotide adenylyltransferase/ribosylnicotinamide kinase NadR 0.80 OLJFJH_02485 protease modulator HflC low > 58
Dickeya dianthicola ME23 0.87 DZA65_RS02480 multifunctional transcriptional regulator/nicotinamide-nucleotide adenylyltransferase/ribosylnicotinamide kinase NadR 0.75 DZA65_RS19665 protease modulator HflC low > 75
Dickeya dianthicola 67-19 0.87 HGI48_RS02375 multifunctional transcriptional regulator/nicotinamide-nucleotide adenylyltransferase/ribosylnicotinamide kinase NadR 0.75 HGI48_RS18530 protease modulator HflC low > 71
Pectobacterium carotovorum WPP14 0.87 HER17_RS19090 multifunctional transcriptional regulator/nicotinamide-nucleotide adenylyltransferase/ribosylnicotinamide kinase NadR 0.78 HER17_RS02600 protease modulator HflC low > 75
Serratia liquefaciens MT49 0.84 IAI46_02950 multifunctional transcriptional regulator/nicotinamide-nucleotide adenylyltransferase/ribosylnicotinamide kinase NadR 0.79 IAI46_01640 protease modulator HflC 0.62 7
Sphingobium sp. HT1-2 0.14 GFF1288 Ribosylnicotinamide kinase (EC 2.7.1.22) 0.15 GFF2901 HflC protein low > 95

Not shown: 2 genomes with orthologs for BWI76_RS04170 only; 69 genomes with orthologs for BWI76_RS02550 only