Conservation of cofitness between Atu3290 and Atu4097 in Agrobacterium fabrum C58

95 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Agrobacterium fabrum C58 1.0 Atu3290 phosphomethylpyrimidine kinase 1.0 Atu4097 L-aspartate oxidase 0.82 7
Sinorhizobium meliloti 1021 0.59 SM_b20962 phoshomethylpyrimidine kinase 0.38 SMc02599 L-aspartate oxidase low > 103
Xanthobacter sp. DMC5 0.55 GFF1029 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase 0.44 GFF1848 L-aspartate oxidase — —
Rhodopseudomonas palustris CGA009 0.53 TX73_020570 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.38 TX73_005420 L-aspartate oxidase — —
Enterobacter asburiae PDN3 0.51 EX28DRAFT_0469 hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.26 EX28DRAFT_0071 L-aspartate oxidase (EC 1.4.3.16) 0.64 4
Pectobacterium carotovorum WPP14 0.50 HER17_RS06265 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.26 HER17_RS05775 L-aspartate oxidase low > 75
Escherichia coli ECRC101 0.50 MCAODC_21085 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.27 MCAODC_11900 nadB L-aspartate oxidase 0.61 2
Klebsiella michiganensis M5al 0.50 BWI76_RS19375 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.27 BWI76_RS21360 L-aspartate oxidase 0.26 9
Escherichia coli ECOR27 0.50 NOLOHH_15415 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.27 NOLOHH_13045 nadB L-aspartate oxidase 0.69 12
Escherichia coli ECRC62 0.50 BNILDI_14330 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.27 BNILDI_11845 nadB L-aspartate oxidase 0.78 3
Escherichia coli BW25113 0.50 b2103 thiD phosphomethylpyrimidine kinase (NCBI) 0.27 b2574 nadB L-aspartate oxidase (NCBI) 0.55 14
Escherichia coli ECRC102 0.50 NIAGMN_22020 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.27 NIAGMN_19140 nadB L-aspartate oxidase 0.68 19
Escherichia coli ECRC99 0.50 KEDOAH_04075 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.27 KEDOAH_06850 nadB L-aspartate oxidase — —
Escherichia coli HS(pFamp)R (ATCC 700891) 0.50 OHPLBJKB_01607 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase 0.27 OHPLBJKB_01133 L-aspartate oxidase low > 74
Escherichia coli ECRC98 0.50 JDDGAC_28185 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.27 JDDGAC_25035 nadB L-aspartate oxidase low > 87
Escherichia coli ECRC100 0.50 OKFHMN_24075 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.27 OKFHMN_21370 nadB L-aspartate oxidase 0.85 25
Escherichia coli ECOR38 0.50 HEPCGN_02760 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.26 HEPCGN_20515 nadB L-aspartate oxidase 0.71 30
Escherichia coli BL21 0.50 ECD_02031 hydroxy-methylpyrimidine kinase and hydroxy-phosphomethylpyrimidine kinase 0.27 ECD_02468 quinolinate synthase, L-aspartate oxidase (B protein) subunit low > 61
Escherichia fergusonii Becca 0.50 EFB2_01754 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase 0.27 EFB2_01322 L-aspartate oxidase low > 86
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.50 GFF3834 Hydroxymethylpyrimidine phosphate kinase ThiD (EC 2.7.4.7) 0.27 GFF2106 L-aspartate oxidase (EC 1.4.3.16) low > 78
Enterobacter sp. TBS_079 0.50 MPMX20_03076 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase 0.26 MPMX20_03445 L-aspartate oxidase low > 85
Rahnella sp. WP5 0.50 EX31_RS20390 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.27 EX31_RS21795 L-aspartate oxidase 0.36 63
Serratia liquefaciens MT49 0.50 IAI46_19100 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.25 IAI46_19590 L-aspartate oxidase low > 86
Klebsiella pneumoniae MKP103 0.49 KDGMDA_26425 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.27 KDGMDA_28485 L-aspartate oxidase low > 95
Dickeya dadantii 3937 0.49 DDA3937_RS15335 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.28 DDA3937_RS15770 L-aspartate oxidase 0.72 27
Escherichia coli Nissle 1917 0.49 ECOLIN_RS12335 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.27 ECOLIN_RS14570 L-aspartate oxidase — —
Pantoea agglomerans CFBP13505 P0401 0.48 PagCFBP13505_RS00915 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.26 PagCFBP13505_RS14735 L-aspartate oxidase low > 74
Dickeya dianthicola 67-19 0.48 HGI48_RS15410 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.28 HGI48_RS15855 L-aspartate oxidase 0.78 32
Dickeya dianthicola ME23 0.48 DZA65_RS16235 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.28 DZA65_RS16935 L-aspartate oxidase 0.81 16
Pantoea sp. MT58 0.47 IAI47_06810 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.26 IAI47_04845 L-aspartate oxidase low > 76
Paraburkholderia sabiae LMG 24235 0.46 QEN71_RS06305 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.29 QEN71_RS03070 L-aspartate oxidase — —
Paraburkholderia bryophila 376MFSha3.1 0.46 H281DRAFT_00587 hydroxymethylpyrimidine kinase /phosphomethylpyrimidine kinase 0.29 H281DRAFT_04069 L-aspartate oxidase — —
Parabacteroides merdae CL09T00C40 0.45 HMPREF1078_RS03470 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.25 HMPREF1078_RS06605 L-aspartate oxidase — —
Burkholderia phytofirmans PsJN 0.45 BPHYT_RS12250 phosphomethylpyrimidine kinase 0.30 BPHYT_RS15640 L-aspartate oxidase — —
Vibrio cholerae E7946 ATCC 55056 0.44 CSW01_06545 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.26 CSW01_12495 L-aspartate oxidase low > 62
Bacteroides thetaiotaomicron VPI-5482 0.44 BT0790 phosphomethylpyrimidine kinase (NCBI ptt file) 0.27 BT3184 L-aspartate oxidase (NCBI ptt file) 0.43 16
Paraburkholderia graminis OAS925 0.43 ABIE53_002529 hydroxymethylpyrimidine/phosphomethylpyrimidine kinase 0.29 ABIE53_003292 L-aspartate oxidase — —
Rhizobium sp. OAE497 0.43 ABIE40_RS25930 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.59 ABIE40_RS23260 L-aspartate oxidase low > 107
Phocaeicola vulgatus CL09T03C04 0.43 HMPREF1058_RS06820 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.26 HMPREF1058_RS11085 L-aspartate oxidase — —
Phocaeicola dorei CL03T12C01 0.42 ABI39_RS20615 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.26 ABI39_RS05945 L-aspartate oxidase — —
Bacteroides stercoris CC31F 0.42 HMPREF1181_RS14705 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.26 HMPREF1181_RS01800 L-aspartate oxidase — —
Bacteroides ovatus ATCC 8483 0.42 BACOVA_02530 phosphomethylpyrimidine kinase 0.26 BACOVA_02888 L-aspartate oxidase 0.78 10
Castellaniella sp019104865 MT123 0.41 ABCV34_RS14505 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.28 ABCV34_RS03690 L-aspartate oxidase — —
Methylophilus sp. DMC18 0.41 GFF892 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase 0.27 GFF2729 L-aspartate oxidase — —
Hydrogenophaga sp. GW460-11-11-14-LB1 0.41 GFF249 Hydroxymethylpyrimidine phosphate kinase ThiD (EC 2.7.4.7) 0.27 GFF1214 L-aspartate oxidase (EC 1.4.3.16) low > 90
Pedobacter sp. GW460-11-11-14-LB5 0.40 CA265_RS24160 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.28 CA265_RS21185 L-aspartate oxidase low > 88
Acidovorax sp. GW101-3H11 0.39 Ac3H11_1063 Hydroxymethylpyrimidine phosphate kinase ThiD (EC 2.7.4.7) 0.28 Ac3H11_3824 L-aspartate oxidase (EC 1.4.3.16) — —
Rhodospirillum rubrum S1H 0.38 Rru_A1102 Phosphomethylpyrimidine kinase (NCBI) 0.36 Rru_A1433 L-aspartate oxidase (NCBI) — —
Rhodanobacter sp000427505 FW510-R12 0.38 LRK53_RS03825 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.28 LRK53_RS14705 FAD-dependent oxidoreductase low > 59
Mucilaginibacter yixingensis YX-36 DSM 26809 0.36 ABZR88_RS08810 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.28 ABZR88_RS20645 L-aspartate oxidase — —
Bifidobacterium breve UCC2003 0.36 BBR_RS17215 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.30 BBR_RS16725 L-aspartate oxidase low > 34
Desulfovibrio vulgaris Hildenborough JW710 0.36 DVU0931 thiD phosphomethylpyrimidine kinase (TIGR) 0.23 DVU1809 nadB L-aspartate oxidase (TIGR) — —
Variovorax sp. OAS795 0.35 ABID97_RS15330 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.28 ABID97_RS07440 L-aspartate oxidase — —
Azospirillum brasilense Sp245 0.35 AZOBR_RS07045 phosphomethylpyrimidine kinase 0.28 AZOBR_RS18685 L-aspartate oxidase — —
Ralstonia solanacearum IBSBF1503 0.35 RALBFv3_RS09905 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.30 RALBFv3_RS04725 L-aspartate oxidase — —
Ralstonia solanacearum UW163 0.35 UW163_RS03675 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.30 UW163_RS08945 L-aspartate oxidase — —
Ralstonia sp. UNC404CL21Col 0.35 ABZR87_RS04830 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.30 ABZR87_RS00345 L-aspartate oxidase — —
Ralstonia solanacearum GMI1000 0.34 RS_RS00495 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.30 RS_RS12285 L-aspartate oxidase — —
Caulobacter crescentus NA1000 0.34 CCNA_03331 phosphomethylpyrimidine kinase/hydroxymethylpyrimidine kinase 0.31 CCNA_03007 L-aspartate oxidase — —
Caulobacter crescentus NA1000 Δfur 0.34 CCNA_03331 phosphomethylpyrimidine kinase/hydroxymethylpyrimidine kinase 0.31 CCNA_03007 L-aspartate oxidase — —
Ralstonia solanacearum PSI07 0.34 RPSI07_RS23455 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.31 RPSI07_RS12660 L-aspartate oxidase — —
Azospirillum sp. SherDot2 0.33 MPMX19_06182 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase 0.34 MPMX19_05671 L-aspartate oxidase — —
Brevundimonas sp. GW460-12-10-14-LB2 0.33 A4249_RS15985 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.31 A4249_RS00630 L-aspartate oxidase — —
Sphingobium sp. HT1-2 0.33 GFF2573 Hydroxymethylpyrimidine phosphate kinase ThiD (EC 2.7.4.7) 0.25 GFF3783 L-aspartate oxidase (EC 1.4.3.16) low > 95
Desulfovibrio vulgaris Miyazaki F 0.32 DvMF_1376 phosphomethylpyrimidine kinase (RefSeq) 0.24 DvMF_0526 L-aspartate oxidase (RefSeq) — —
Cupriavidus basilensis FW507-4G11 0.31 RR42_RS01370 phosphomethylpyrimidine kinase 0.29 RR42_RS17010 L-aspartate oxidase — —
Synechococcus elongatus PCC 7942 0.30 Synpcc7942_2379 thiD phosphomethylpyrimidine kinase 0.28 Synpcc7942_1881 nadB L-aspartate oxidase low > 38
Magnetospirillum magneticum AMB-1 0.29 AMB_RS16155 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.24 AMB_RS19650 L-aspartate oxidase — —
Rhodanobacter sp. FW510-T8 0.29 OKGIIK_03835 Bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.23 OKGIIK_00935 L-aspartate oxidase low > 53
Acinetobacter radioresistens SK82 0.28 MPMX26_02438 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase 0.26 MPMX26_02162 L-aspartate oxidase — —
Acinetobacter baumannii LAC-4 0.28 RR41_RS15160 hydroxymethylpyrimidine/phosphomethylpyrimidine kinase 0.25 RR41_RS04820 L-aspartate oxidase — —
Pseudomonas aeruginosa PA14 0.27 IKLFDK_20515 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.27 IKLFDK_03260 L-aspartate oxidase low > 100
Sphingomonas koreensis DSMZ 15582 0.27 Ga0059261_1961 hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.25 Ga0059261_2248 L-aspartate oxidase (EC 1.4.3.16) — —
Dechlorosoma suillum PS 0.27 Dsui_0662 phosphomethylpyrimidine kinase 0.28 Dsui_2452 L-aspartate oxidase — —
Pseudomonas putida KT2440 0.27 PP_4782 Phosphomethylpyrimidine kinase 0.27 PP_1426 L-aspartate oxidase 0.52 26
Pseudomonas sp. BP01 0.27 JOY50_RS21745 hydroxymethylpyrimidine/phosphomethylpyrimidine kinase 0.27 JOY50_RS14660 nadB L-aspartate oxidase low > 84
Pseudomonas simiae WCS417 0.27 PS417_24600 hydrogenase 0.27 PS417_07115 L-aspartate oxidase low > 88
Pseudomonas fluorescens FW300-N2C3 0.27 AO356_15435 hydrogenase 0.26 AO356_04580 L-aspartate oxidase low > 104
Pseudomonas sp. SVBP6 0.26 COO64_RS15485 hydroxymethylpyrimidine/phosphomethylpyrimidine kinase 0.27 COO64_RS16520 nadB L-aspartate oxidase low > 93
Pseudomonas fluorescens SBW25-INTG 0.26 PFLU_RS26530 hydroxymethylpyrimidine/phosphomethylpyrimidine kinase 0.27 PFLU_RS07225 L-aspartate oxidase low > 109
Pseudomonas sp. S08-1 0.26 OH686_09185 Hydroxymethylpyrimidine phosphate kinase ThiD 0.27 OH686_20040 L-aspartate oxidase 0.65 14
Pseudomonas fluorescens FW300-N2E3 0.26 AO353_06350 hydrogenase 0.28 AO353_17620 L-aspartate oxidase 0.28 68
Pseudomonas fluorescens SBW25 0.26 PFLU_RS26530 hydroxymethylpyrimidine/phosphomethylpyrimidine kinase 0.27 PFLU_RS07225 L-aspartate oxidase low > 109
Mycobacterium tuberculosis H37Rv 0.26 Rv0422c Probable phosphomethylpyrimidine kinase ThiD (HMP-phosphate kinase) (HMP-P kinase) 0.29 Rv1595 Probable L-aspartate oxidase NadB — —
Pseudomonas fluorescens GW456-L13 0.26 PfGW456L13_1385 Hydroxymethylpyrimidine phosphate kinase ThiD (EC 2.7.4.7) 0.28 PfGW456L13_4517 L-aspartate oxidase (EC 1.4.3.16) low > 87
Pseudomonas sp. DMC3 0.26 GFF3905 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase 0.26 GFF2276 L-aspartate oxidase low > 89
Pseudomonas syringae pv. syringae B728a ΔmexB 0.26 Psyr_4340 phosphomethylpyrimidine kinase, putative 0.27 Psyr_3959 L-aspartate oxidase low > 86
Pseudomonas syringae pv. syringae B728a 0.26 Psyr_4340 phosphomethylpyrimidine kinase, putative 0.27 Psyr_3959 L-aspartate oxidase low > 86
Pseudomonas stutzeri RCH2 0.26 Psest_0537 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase 0.27 Psest_3101 L-aspartate oxidase low > 67
Pseudomonas segetis P6 0.25 MPMX49_01077 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase 0.26 MPMX49_01399 L-aspartate oxidase low > 75
Pseudomonas sp. RS175 0.24 PFR28_03843 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase 0.27 PFR28_00689 L-aspartate oxidase 0.40 25
Herbaspirillum seropedicae SmR1 0.24 HSERO_RS02135 phosphomethylpyrimidine kinase 0.28 HSERO_RS11085 L-aspartate oxidase 0.39 33
Pseudomonas fluorescens FW300-N1B4 0.23 Pf1N1B4_2718 Hydroxymethylpyrimidine phosphate kinase ThiD (EC 2.7.4.7) 0.27 Pf1N1B4_3322 L-aspartate oxidase (EC 1.4.3.16) low > 87
Pseudomonas fluorescens FW300-N2E2 0.23 Pf6N2E2_5024 Hydroxymethylpyrimidine phosphate kinase ThiD (EC 2.7.4.7) 0.25 Pf6N2E2_2758 L-aspartate oxidase (EC 1.4.3.16) low > 103
Pseudomonas lactucae CFBP13502 0.23 GEMAOFIL_05068 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase 0.28 GEMAOFIL_01571 L-aspartate oxidase low > 93
Phaeobacter inhibens DSM 17395 0.19 PGA1_c09030 phosphomethylpyrimidine kinase ThiD 0.32 PGA1_c27800 L-aspartate oxidase NadB low > 62

Not shown: 12 genomes with orthologs for Atu3290 only; 10 genomes with orthologs for Atu4097 only