Conservation of cofitness between SO2071 and SO4235 in Shewanella oneidensis MR-1

52 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Shewanella oneidensis MR-1 1.0 SO2071 hisB imidazoleglycerol-phosphate dehydratase/histidinol-phosphatase (NCBI ptt file) 1.0 SO4235 leuB 3-isopropylmalate dehydrogenase (NCBI ptt file) 0.98 6
Shewanella sp. ANA-3 0.98 Shewana3_1851 imidazole glycerol-phosphate dehydratase/histidinol phosphatase (RefSeq) 0.99 Shewana3_3760 3-isopropylmalate dehydrogenase (RefSeq) 0.95 22
Shewanella amazonensis SB2B 0.85 Sama_1944 imidazole glycerol-phosphate dehydratase/histidinol phosphatase (RefSeq) 0.89 Sama_0336 3-isopropylmalate dehydrogenase (RefSeq) 0.94 23
Shewanella loihica PV-4 0.82 Shew_2200 imidazole glycerol-phosphate dehydratase/histidinol phosphatase (RefSeq) 0.88 Shew_3471 3-isopropylmalate dehydrogenase (RefSeq) 0.99 4
Alteromonas macleodii MIT1002 0.69 MIT1002_02635 Histidine biosynthesis bifunctional protein HisB 0.67 MIT1002_00948 3-isopropylmalate dehydrogenase 0.95 40
Vibrio cholerae E7946 ATCC 55056 0.66 CSW01_05760 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase 0.71 CSW01_12600 3-isopropylmalate dehydrogenase low > 62
Pectobacterium carotovorum WPP14 0.64 HER17_RS12240 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.69 HER17_RS03080 3-isopropylmalate dehydrogenase 0.96 17
Serratia liquefaciens MT49 0.64 IAI46_08200 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.71 IAI46_03350 3-isopropylmalate dehydrogenase low > 86
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.63 GFF3910 Histidinol-phosphatase (EC 3.1.3.15) / Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) 0.70 GFF165 3-isopropylmalate dehydrogenase (EC 1.1.1.85) low > 78
Dickeya dadantii 3937 0.63 DDA3937_RS09725 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.70 DDA3937_RS18120 3-isopropylmalate dehydrogenase low > 74
Dickeya dianthicola 67-19 0.63 HGI48_RS09735 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.70 HGI48_RS18060 3-isopropylmalate dehydrogenase 0.67 52
Escherichia coli ECOR38 0.62 HEPCGN_03210 hisB bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.70 HEPCGN_08700 leuB 3-isopropylmalate dehydrogenase 0.96 16
Escherichia coli BW25113 0.62 b2022 hisB imidazoleglycerolphosphate dehydratase and histidinol-phosphate phosphatase (VIMSS) 0.69 b0073 leuB 3-isopropylmalate dehydrogenase (VIMSS) 0.96 9
Escherichia coli ECRC62 0.62 BNILDI_14730 hisB bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.69 BNILDI_08545 leuA 2-isopropylmalate synthase 0.90 17
Dickeya dianthicola ME23 0.62 DZA65_RS10045 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.70 DZA65_RS19205 3-isopropylmalate dehydrogenase 0.72 36
Escherichia coli ECRC100 0.62 OKFHMN_24505 hisB bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.70 OKFHMN_10720 leuB 3-isopropylmalate dehydrogenase 0.96 2
Escherichia coli ECOR27 0.62 NOLOHH_15820 hisB bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.69 NOLOHH_03065 leuA 2-isopropylmalate synthase 0.92 25
Escherichia coli ECRC101 0.62 MCAODC_20435 hisB bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.70 MCAODC_01235 leuB 3-isopropylmalate dehydrogenase 0.85 8
Escherichia coli ECRC102 0.62 NIAGMN_22450 hisB bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.70 NIAGMN_08570 leuB 3-isopropylmalate dehydrogenase 0.97 2
Escherichia coli Nissle 1917 0.62 ECOLIN_RS11955 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.70 ECOLIN_RS00395 3-isopropylmalate dehydrogenase — —
Escherichia coli ECRC99 0.62 KEDOAH_03645 hisB bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.70 KEDOAH_17435 leuB 3-isopropylmalate dehydrogenase — —
Escherichia coli ECRC98 0.62 JDDGAC_28615 hisB bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.70 JDDGAC_14315 leuB 3-isopropylmalate dehydrogenase 0.79 4
Erwinia amylovora T8 0.62 OLJFJH_12170 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.68 OLJFJH_01290 3-isopropylmalate dehydrogenase 0.88 23
Rahnella sp. WP5 0.62 EX31_RS11450 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.71 EX31_RS03685 3-isopropylmalate dehydrogenase 0.96 7
Escherichia fergusonii Becca 0.62 EFB2_01834 Histidine biosynthesis bifunctional protein HisB 0.70 EFB2_03972 3-isopropylmalate dehydrogenase low > 86
Escherichia coli HS(pFamp)R (ATCC 700891) 0.62 OHPLBJKB_01678 Histidine biosynthesis bifunctional protein HisB 0.69 OHPLBJKB_03584 3-isopropylmalate dehydrogenase low > 74
Escherichia coli BL21 0.62 ECD_01924 histidinol-phosphatase and imidazoleglycerol-phosphate dehydratase 0.69 ECD_00075 3-isopropylmalate dehydrogenase, NAD(+)-dependent 0.92 8
Klebsiella pneumoniae MKP103 0.62 KDGMDA_26105 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.69 KDGMDA_12905 3-isopropylmalate dehydrogenase low > 95
Erwinia tracheiphila SCR3 0.62 LU632_RS08935 hisB bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.67 LU632_RS02875 leuB 3-isopropylmalate dehydrogenase 0.81 22
Klebsiella michiganensis M5al 0.62 BWI76_RS18935 bifunctional imidazole glycerol-phosphate dehydratase/histidinol phosphatase 0.68 BWI76_RS04675 3-isopropylmalate dehydrogenase 0.87 31
Pantoea agglomerans CFBP13505 P0401 0.61 PagCFBP13505_RS01200 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.66 PagCFBP13505_RS12995 3-isopropylmalate dehydrogenase low > 74
Enterobacter asburiae PDN3 0.61 EX28DRAFT_0537 imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) 0.70 EX28DRAFT_3669 3-isopropylmalate dehydrogenase 0.93 6
Erwinia tracheiphila HP pepo 2.2 0.61 IJEDHG_19080 hisB bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.67 IJEDHG_06000 leuB 3-isopropylmalate dehydrogenase 0.81 13
Enterobacter sp. TBS_079 0.61 MPMX20_03004 Histidine biosynthesis bifunctional protein HisB 0.69 MPMX20_00768 3-isopropylmalate dehydrogenase 0.92 25
Pantoea sp. MT58 0.61 IAI47_07080 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.65 IAI47_16005 3-isopropylmalate dehydrogenase 0.97 14
Rhodanobacter sp. FW510-T8 0.52 OKGIIK_04960 hisB bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.41 OKGIIK_13595 leuB 3-isopropylmalate dehydrogenase low > 53
Lysobacter sp. OAE881 0.52 ABIE51_RS13315 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.42 ABIE51_RS17585 3-isopropylmalate dehydrogenase 0.82 40
Dyella japonica UNC79MFTsu3.2 0.52 ABZR86_RS06720 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.39 ABZR86_RS15950 3-isopropylmalate dehydrogenase 0.92 33
Rhodanobacter denitrificans MT42 0.51 LRK55_RS01375 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.42 LRK55_RS09965 3-isopropylmalate dehydrogenase low > 63
Rhodanobacter denitrificans FW104-10B01 0.51 LRK54_RS01595 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.41 LRK54_RS10325 3-isopropylmalate dehydrogenase 0.58 21
Rhodanobacter sp000427505 FW510-R12 0.51 LRK53_RS08470 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.44 LRK53_RS03100 3-isopropylmalate dehydrogenase 0.64 49
Xanthomonas campestris pv. campestris strain 8004 0.49 Xcc-8004.2946.1 Histidinol-phosphatase (EC 3.1.3.15) / Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) 0.47 Xcc-8004.1053.1 3-isopropylmalate dehydrogenase (EC 1.1.1.85) 0.93 6
Bacteroides stercoris CC31F 0.46 HMPREF1181_RS04850 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.39 HMPREF1181_RS14125 3-isopropylmalate dehydrogenase 0.89 29
Bacteroides ovatus ATCC 8483 0.46 BACOVA_01232 histidinol-phosphatase 0.39 BACOVA_04600 3-isopropylmalate dehydrogenase 0.91 25
Bacteroides thetaiotaomicron VPI-5482 0.46 BT0203 histidine biosynthesis bifunctional protein hisB (NCBI ptt file) 0.39 BT1857 3-isopropylmalate dehydrogenase (NCBI ptt file) 0.83 37
Pontibacter actiniarum KMM 6156, DSM 19842 0.45 CA264_05040 bifunctional imidazole glycerol-phosphate dehydratase/histidinol phosphatase 0.42 CA264_09445 3-isopropylmalate dehydrogenase low > 74
Echinicola vietnamensis KMM 6221, DSM 17526 0.45 Echvi_2457 histidinol-phosphatase 0.40 Echvi_2062 3-isopropylmalate dehydrogenase — —
Parabacteroides merdae CL09T00C40 0.44 HMPREF1078_RS02440 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.38 HMPREF1078_RS16640 3-isopropylmalate dehydrogenase 0.93 24
Phocaeicola vulgatus CL09T03C04 0.44 HMPREF1058_RS15885 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.39 HMPREF1058_RS14565 3-isopropylmalate dehydrogenase 0.83 30
Phocaeicola dorei CL03T12C01 0.44 ABI39_RS11845 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.39 ABI39_RS10215 3-isopropylmalate dehydrogenase 0.79 37
Cellulophaga baltica 18 0.43 M666_RS17145 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.38 M666_RS13575 3-isopropylmalate dehydrogenase low > 67
Mucilaginibacter yixingensis YX-36 DSM 26809 0.43 ABZR88_RS06870 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.40 ABZR88_RS11605 3-isopropylmalate dehydrogenase — —
Pedobacter sp. GW460-11-11-14-LB5 0.42 CA265_RS03625 bifunctional imidazole glycerol-phosphate dehydratase/histidinol phosphatase 0.39 CA265_RS15850 3-isopropylmalate dehydrogenase 0.92 19

Not shown: 0 genomes with orthologs for SO2071 only; 64 genomes with orthologs for SO4235 only