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  • Top cofit genes for Rv2761c from Mycobacterium tuberculosis H37Rv

    Possible type I restriction/modification system specificity determinant HsdS (S protein)
    SEED: Type I restriction-modification system, specificity subunit S (EC 3.1.21.3)

    Rank Hit Name Description Conserved? Cofitness  
    1 Rv3070 Probable conserved integral membrane protein no 0.29
    2 Rv0131c Probable acyl-CoA dehydrogenase FadE1 no 0.26
    3 Rv3519 Unknown protein no 0.25
    4 Rv0901 Possible conserved exported or membrane protein no 0.25
    5 Rv1097c Probable membrane glycine and proline rich protein no 0.24
    6 Rv3270 Probable metal cation-transporting P-type ATPase C CtpC no 0.24
    7 Rv2659c Probable PhiRv2 prophage integrase no 0.23
    8 Rv0274 Conserved protein no 0.22
    9 Rv1598c Conserved protein no 0.22
    10 Rv2872 Possible toxin VapC43. Contains PIN domain. no 0.22
    11 Rv3472 Conserved protein no 0.22
    12 Rv0275c Possible transcriptional regulatory protein (possibly TetR-family) no 0.22
    13 Rv2041c Probable sugar-binding lipoprotein no 0.22
    14 Rv2079 Conserved hypothetical protein no 0.22
    15 Rv2688c Antibiotic-transport ATP-binding protein ABC transporter no 0.21
    16 Rv2270 Probable lipoprotein LppN no 0.21
    17 Rv2378c Lysine-N-oxygenase MbtG (L-lysine 6-monooxygenase) (lysine N6-hydroxylase) no 0.21
    18 Rv2089c Dipeptidase PepE no 0.21
    19 Rv0771 Possible 4-carboxymuconolactone decarboxylase (CMD) no 0.21
    20 Rv0393 Conserved 13E12 repeat family protein no 0.21

    Or look for negative cofitness